La maladie de Parkinson en France (serveur d'exploration)

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Gut feelings about smoking and coffee in Parkinson's disease.

Identifieur interne : 000541 ( PubMed/Corpus ); précédent : 000540; suivant : 000542

Gut feelings about smoking and coffee in Parkinson's disease.

Auteurs : Pascal Derkinderen ; Kathleen M. Shannon ; Patrik Brundin

Source :

RBID : pubmed:24753353

English descriptors

Abstract

Strong epidemiologic evidence suggests that smokers and coffee drinkers have a lower risk of Parkinson's disease (PD). The explanation for this finding is still unknown, and the discussion has focused on two main hypotheses. The first suggests that PD patients have premorbid personality traits associated with dislike for coffee-drinking and smoking. The second posits that caffeine and nicotine are neuroprotective. We propose an alternative third hypothesis, in which both cigarette and coffee consumption change the composition of the microbiota in the gut in a way that mitigates intestinal inflammation. This, in turn, would lead to less misfolding of the protein alpha-synuclein in enteric nerves, reducing the risk of PD by minimizing propagation of the protein aggregates to the central nervous system, where they otherwise can induce neurodegeneration.

DOI: 10.1002/mds.25882
PubMed: 24753353

Links to Exploration step

pubmed:24753353

Le document en format XML

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<div type="abstract" xml:lang="en">Strong epidemiologic evidence suggests that smokers and coffee drinkers have a lower risk of Parkinson's disease (PD). The explanation for this finding is still unknown, and the discussion has focused on two main hypotheses. The first suggests that PD patients have premorbid personality traits associated with dislike for coffee-drinking and smoking. The second posits that caffeine and nicotine are neuroprotective. We propose an alternative third hypothesis, in which both cigarette and coffee consumption change the composition of the microbiota in the gut in a way that mitigates intestinal inflammation. This, in turn, would lead to less misfolding of the protein alpha-synuclein in enteric nerves, reducing the risk of PD by minimizing propagation of the protein aggregates to the central nervous system, where they otherwise can induce neurodegeneration.</div>
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<CommentsCorrectionsList>
<CommentsCorrections RefType="Cites">
<RefSource>Parkinsonism Relat Disord. 2011 Jul;17(6):446-50</RefSource>
<PMID Version="1">21458354</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Neurosci Lett. 2006 Mar 20;396(1):67-72</RefSource>
<PMID Version="1">16330147</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Neurogastroenterol Motil. 2012 Apr;24(4):e202-5</RefSource>
<PMID Version="1">22292943</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Eur J Neurol. 2012 Jun;19(6):864-9</RefSource>
<PMID Version="1">22248366</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Neurotoxicology. 2012 Jun;33(3):347-60</RefSource>
<PMID Version="1">22330755</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Mov Disord. 2012 May;27(6):716-9</RefSource>
<PMID Version="1">22550057</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>J Neurol. 2012 Jun;259(6):1029-38</RefSource>
<PMID Version="1">22083431</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Nature. 2012 Sep 13;489(7415):220-30</RefSource>
<PMID Version="1">22972295</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Nat Rev Microbiol. 2012 Nov;10(11):735-42</RefSource>
<PMID Version="1">23000955</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Curr Opin Gastroenterol. 2012 Nov;28(6):557-62</RefSource>
<PMID Version="1">23010679</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>PLoS One. 2012;7(10):e47387</RefSource>
<PMID Version="1">23082161</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Neurobiol Dis. 2013 Feb;50:42-8</RefSource>
<PMID Version="1">23017648</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Mol Neurobiol. 2013 Apr;47(2):561-74</RefSource>
<PMID Version="1">22544647</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>PLoS One. 2013;8(3):e59260</RefSource>
<PMID Version="1">23516617</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>FEMS Microbiol Lett. 2013 Jun;343(2):161-8</RefSource>
<PMID Version="1">23551139</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Mov Disord. 2013 Aug;28(9):1241-9</RefSource>
<PMID Version="1">23712625</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Acta Neuropathol. 2014 Feb;127(2):235-41</RefSource>
<PMID Version="1">24240814</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>J Neurosci. 2001 May 15;21(10):RC143</RefSource>
<PMID Version="1">11319241</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>J Virol. 2001 Oct;75(19):9320-7</RefSource>
<PMID Version="1">11533195</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Ann Neurol. 2002 Sep;52(3):276-84</RefSource>
<PMID Version="1">12205639</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Neurobiol Aging. 2003 Mar-Apr;24(2):197-211</RefSource>
<PMID Version="1">12498954</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Am J Epidemiol. 1968 Sep;88(2):149-58</RefSource>
<PMID Version="1">5673487</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Am J Physiol. 1987 Aug;253(2 Pt 2):R361-70</RefSource>
<PMID Version="1">3618835</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>J Neurochem. 1998 Dec;71(6):2439-46</RefSource>
<PMID Version="1">9832142</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>J Neurol Neurosurg Psychiatry. 2006 Mar;77(3):317-21</RefSource>
<PMID Version="1">16484638</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Neuropathol Appl Neurobiol. 2007 Dec;33(6):599-614</RefSource>
<PMID Version="1">17961138</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Neuroscience. 2008 May 15;153(3):733-50</RefSource>
<PMID Version="1">18407422</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Mov Disord. 2008 Jun 15;23(8):1065-75</RefSource>
<PMID Version="1">18442139</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Brain Behav Immun. 2009 Jan;23(1):55-63</RefSource>
<PMID Version="1">18678243</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>J Neurosci Methods. 2009 Mar 30;178(1):1-9</RefSource>
<PMID Version="1">19056424</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Int J Food Microbiol. 2009 Mar 31;130(2):117-21</RefSource>
<PMID Version="1">19217682</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Prog Brain Res. 2010;184:133-57</RefSource>
<PMID Version="1">20887873</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Lancet Neurol. 2010 Nov;9(11):1128-38</RefSource>
<PMID Version="1">20846907</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Mov Disord. 2011 Apr;26(5):889-92</RefSource>
<PMID Version="1">21520278</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Nature. 2011 Nov 24;479(7374):538-41</RefSource>
<PMID Version="1">22031325</PMID>
</CommentsCorrections>
<CommentsCorrections RefType="Cites">
<RefSource>Eur J Epidemiol. 2011 Jun;26 Suppl 1:S1-58</RefSource>
<PMID Version="1">21626386</PMID>
</CommentsCorrections>
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