Sleepiness in Idiopathic REM Sleep Behavior Disorder and Parkinson Disease.
Identifieur interne : 000294 ( PubMed/Corpus ); précédent : 000293; suivant : 000295Sleepiness in Idiopathic REM Sleep Behavior Disorder and Parkinson Disease.
Auteurs : Isabelle Arnulf ; Dulce Neutel ; Bastien Herlin ; Jean-Louis Golmard ; Smaranda Leu-Semenescu ; Valérie Cochen De Cock ; Marie VidailhetSource :
- Sleep [ 1550-9109 ] ; 2015.
English descriptors
- KwdEn :
- Aged, Arousal, Brain Stem (pathology), Dementia (complications), Female, Follow-Up Studies, Humans, Male, Middle Aged, Multiple System Atrophy (complications), Parkinson Disease (etiology), Parkinson Disease (physiopathology), Parkinsonian Disorders (complications), Polysomnography, REM Sleep Behavior Disorder (complications), REM Sleep Behavior Disorder (diagnosis), REM Sleep Behavior Disorder (physiopathology), Retrospective Studies, Sleep Stages (physiology), Time Factors.
- MESH :
- complications : Dementia, Multiple System Atrophy, Parkinsonian Disorders, REM Sleep Behavior Disorder.
- diagnosis : REM Sleep Behavior Disorder.
- etiology : Parkinson Disease.
- pathology : Brain Stem.
- physiology : Sleep Stages.
- physiopathology : Parkinson Disease, REM Sleep Behavior Disorder.
- Aged, Arousal, Female, Follow-Up Studies, Humans, Male, Middle Aged, Polysomnography, Retrospective Studies, Time Factors.
Abstract
To determine whether patients with idiopathic and symptomatic RBD were sleepier than controls, and if sleepiness in idiopathic RBD predicted earlier conversion to Parkinson disease.
DOI: 10.5665/sleep.5040
PubMed: 26085299
Links to Exploration step
pubmed:26085299Le document en format XML
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UPMC-Paris6), Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Cochen De Cock, Valerie" sort="Cochen De Cock, Valerie" uniqKey="Cochen De Cock V" first="Valérie" last="Cochen De Cock">Valérie Cochen De Cock</name><affiliation><nlm:affiliation>Sleep Disorders Unit, Pitié-Salpêtrière University Hospital, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name><affiliation><nlm:affiliation>Sorbonne Universities, UPMC Univ Paris 06, Paris, France.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:26085299</idno><idno type="pmid">26085299</idno><idno type="doi">10.5665/sleep.5040</idno><idno type="wicri:Area/PubMed/Corpus">000294</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000294</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Sleepiness in Idiopathic REM Sleep Behavior Disorder and Parkinson Disease.</title><author><name sortKey="Arnulf, Isabelle" sort="Arnulf, Isabelle" uniqKey="Arnulf I" first="Isabelle" last="Arnulf">Isabelle Arnulf</name><affiliation><nlm:affiliation>Sorbonne Universities, UPMC Univ Paris 06, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Neutel, Dulce" sort="Neutel, Dulce" uniqKey="Neutel D" first="Dulce" last="Neutel">Dulce Neutel</name><affiliation><nlm:affiliation>Sleep Disorders Unit, Pitié-Salpêtrière University Hospital, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Herlin, Bastien" sort="Herlin, Bastien" uniqKey="Herlin B" first="Bastien" last="Herlin">Bastien Herlin</name><affiliation><nlm:affiliation>Sleep Disorders Unit, Pitié-Salpêtrière University Hospital, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Golmard, Jean Louis" sort="Golmard, Jean Louis" uniqKey="Golmard J" first="Jean-Louis" last="Golmard">Jean-Louis Golmard</name><affiliation><nlm:affiliation>Department of Biostatistics, Salpêtrière Hospital, ER4, Sorbonne Universites, UPMC Univ Paris 06, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Leu Semenescu, Smaranda" sort="Leu Semenescu, Smaranda" uniqKey="Leu Semenescu S" first="Smaranda" last="Leu-Semenescu">Smaranda Leu-Semenescu</name><affiliation><nlm:affiliation>Brain Research Institute (CRICM - UPMC-Paris6), Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Cochen De Cock, Valerie" sort="Cochen De Cock, Valerie" uniqKey="Cochen De Cock V" first="Valérie" last="Cochen De Cock">Valérie Cochen De Cock</name><affiliation><nlm:affiliation>Sleep Disorders Unit, Pitié-Salpêtrière University Hospital, Paris, France.</nlm:affiliation></affiliation></author><author><name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name><affiliation><nlm:affiliation>Sorbonne Universities, UPMC Univ Paris 06, Paris, France.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Sleep</title><idno type="eISSN">1550-9109</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Arousal</term><term>Brain Stem (pathology)</term><term>Dementia (complications)</term><term>Female</term><term>Follow-Up Studies</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Multiple System Atrophy (complications)</term><term>Parkinson Disease (etiology)</term><term>Parkinson Disease (physiopathology)</term><term>Parkinsonian Disorders (complications)</term><term>Polysomnography</term><term>REM Sleep Behavior Disorder (complications)</term><term>REM Sleep Behavior Disorder (diagnosis)</term><term>REM Sleep Behavior Disorder (physiopathology)</term><term>Retrospective Studies</term><term>Sleep Stages (physiology)</term><term>Time Factors</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Dementia</term><term>Multiple System Atrophy</term><term>Parkinsonian Disorders</term><term>REM Sleep Behavior Disorder</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>REM Sleep Behavior Disorder</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Brain Stem</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Sleep Stages</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Parkinson Disease</term><term>REM Sleep Behavior Disorder</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Arousal</term><term>Female</term><term>Follow-Up Studies</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Polysomnography</term><term>Retrospective Studies</term><term>Time Factors</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">To determine whether patients with idiopathic and symptomatic RBD were sleepier than controls, and if sleepiness in idiopathic RBD predicted earlier conversion to Parkinson disease.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26085299</PMID><DateCreated><Year>2015</Year><Month>10</Month><Day>14</Day></DateCreated><DateCompleted><Year>2016</Year><Month>03</Month><Day>10</Day></DateCompleted><DateRevised><Year>2016</Year><Month>04</Month><Day>01</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1550-9109</ISSN><JournalIssue CitedMedium="Internet"><Volume>38</Volume><Issue>10</Issue><PubDate><Year>2015</Year><Month>Oct</Month><Day>01</Day></PubDate></JournalIssue><Title>Sleep</Title><ISOAbbreviation>Sleep</ISOAbbreviation></Journal><ArticleTitle>Sleepiness in Idiopathic REM Sleep Behavior Disorder and Parkinson Disease.</ArticleTitle><Pagination><MedlinePgn>1529-35</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.5665/sleep.5040</ELocationID><Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To determine whether patients with idiopathic and symptomatic RBD were sleepier than controls, and if sleepiness in idiopathic RBD predicted earlier conversion to Parkinson disease.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">The Epworth Sleepiness Scale (ESS) and its determinants were compared at the time of a video-polysomnography for an RBD diagnosis in patients with idiopathic RBD, in patients with Parkinson disease, and in controls. Whether sleepiness at time of RBD diagnosis predicted an earlier conversion to neurodegenerative diseases was retrospectively analyzed in the followed-up patients.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">The 75 patients with idiopathic RBD were sleepier (ESS: 7.8 ± 4.6) at the time of RBD diagnosis than 74 age- and sex-matched controls (ESS: 5.0 ± 3.6, P < 0.0001). They reached the levels of 114 patients with Parkinson disease (ESS: 8.7 ± 4.8), whether they had (n = 78) or did not have (n = 36) concomitant RBD. The severity of sleepiness in idiopathic RBD correlated with younger age, but not with sleep measures. Among the 69 patients with idiopathic RBD who were followed up for a median 3 years (1-15 years), 16 (23.2%) developed parkinsonism (n = 6), dementia (n = 6), dementia plus parkinsonism (n = 2), and multiple system atrophy (n = 2). An ESS greater than 8 at time of RBD diagnosis predicted a shorter time to phenoconversion to parkinsonism and dementia, from RBD onset, and from RBD diagnosis (when adjusted for age and time between RBD onset and diagnosis).</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Sleepiness is associated with idiopathic REM sleep behavior disorder and predicts more rapid conversion to parkinsonism and dementia, suggesting it is an early marker of neuronal loss in brainstem arousal systems.</AbstractText><CopyrightInformation>© 2015 Associated Professional Sleep Societies, LLC.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Arnulf</LastName><ForeName>Isabelle</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Sorbonne Universities, UPMC Univ Paris 06, Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Brain Research Institute (CRICM - UPMC-Paris6), Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Sleep Disorders Unit, Pitié-Salpêtrière University Hospital, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Neutel</LastName><ForeName>Dulce</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Sleep Disorders Unit, Pitié-Salpêtrière University Hospital, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Herlin</LastName><ForeName>Bastien</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Sleep Disorders Unit, Pitié-Salpêtrière University Hospital, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Golmard</LastName><ForeName>Jean-Louis</ForeName><Initials>JL</Initials><AffiliationInfo><Affiliation>Department of Biostatistics, Salpêtrière Hospital, ER4, Sorbonne Universites, UPMC Univ Paris 06, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Leu-Semenescu</LastName><ForeName>Smaranda</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Brain Research Institute (CRICM - UPMC-Paris6), Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Sleep Disorders Unit, Pitié-Salpêtrière University Hospital, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cochen de Cock</LastName><ForeName>Valérie</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Sleep Disorders Unit, Pitié-Salpêtrière University Hospital, Paris, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Vidailhet</LastName><ForeName>Marie</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Sorbonne Universities, UPMC Univ Paris 06, Paris, France.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Brain Research Institute (CRICM - UPMC-Paris6), Paris, France.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>10</Month><Day>01</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>Sleep</MedlineTA><NlmUniqueID>7809084</NlmUniqueID><ISSNLinking>0161-8105</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Arch Neurol. 2005 Aug;62(8):1242-8</RefSource><PMID Version="1">16087765</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Sleep Med Rev. 2005 Jun;9(3):185-200</RefSource><PMID Version="1">15893249</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet Neurol. 2006 Jul;5(7):572-7</RefSource><PMID Version="1">16781987</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Brain. 2007 Feb;130(Pt 2):450-6</RefSource><PMID Version="1">17235126</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Sleep Res. 2007 Mar;16(1):102-9</RefSource><PMID Version="1">17309769</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Nat Clin Pract Neurol. 2008 May;4(5):254-66</RefSource><PMID Version="1">18398415</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 2008 Aug 26;71(9):670-6</RefSource><PMID Version="1">18725592</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Am Geriatr Soc. 2009 Feb;57(2):304-8</RefSource><PMID Version="1">19170786</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 2009 Apr 14;72(15):1296-300</RefSource><PMID Version="1">19109537</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Sleep. 2009 Jun;32(6):753-9</RefSource><PMID Version="1">19544751</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Parkinsonism Relat Disord. 2009 Dec;15 Suppl 3:S101-4</RefSource><PMID Version="1">20082966</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Am Geriatr Soc. 2010 Mar;58(3):480-6</RefSource><PMID Version="1">20398116</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2010 Dec 15;25(16):2704-16</RefSource><PMID Version="1">20931631</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Arch Neurol. 2011 Feb;68(2):223-30</RefSource><PMID Version="1">21320989</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 2011 Aug 30;77(9):875-82</RefSource><PMID Version="1">21849645</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2011 Aug 15;26(10):1931-4</RefSource><PMID Version="1">21656853</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2012 Mar;27(3):428-31</RefSource><PMID Version="1">22173891</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ann Neurol. 2012 Apr;71(4):560-8</RefSource><PMID Version="1">22522445</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2012 May;27(6):677-89</RefSource><PMID Version="1">22447623</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Sleep. 2012 Jun;35(6):835-47</RefSource><PMID Version="1">22654203</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Sleep. 2012 Sep;35(9):1201-7</RefSource><PMID Version="1">22942498</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet Neurol. 2013 May;12(5):443-53</RefSource><PMID Version="1">23562390</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Brain. 2013 Jul;136(Pt 7):2120-9</RefSource><PMID Version="1">23801736</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Sleep Med. 2013 Aug;14(8):744-8</RefSource><PMID Version="1">23347909</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Sleep Med. 2013 Aug;14(8):754-62</RefSource><PMID Version="1">23474058</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>PLoS One. 2014;9(2):e89741</RefSource><PMID Version="1">24587002</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Neurol Neurosurg Psychiatry. 2014 May;85(5):560-6</RefSource><PMID Version="1">24187013</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 2001 Oct 23;57(8):1392-6</RefSource><PMID Version="1">11673578</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>JAMA. 2002 Jan 23-30;287(4):455-63</RefSource><PMID Version="1">11798367</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 2002 Apr 9;58(7):1019-24</RefSource><PMID Version="1">11940685</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Neuropathol Exp Neurol. 2002 May;61(5):413-26</RefSource><PMID Version="1">12030260</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Arch Neurol. 2004 Jan;61(1):97-102</RefSource><PMID Version="1">14732626</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 2003 May 13;60(9):1553-4</RefSource><PMID Version="1">12743258</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Arch Neurol. 2002 Jun;59(6):986-9</RefSource><PMID Version="1">12056935</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Psychiatr Res. 1975 Nov;12(3):189-98</RefSource><PMID Version="1">1202204</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Sleep. 1991 Dec;14(6):540-5</RefSource><PMID Version="1">1798888</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Neurol Neurosurg Psychiatry. 1992 Mar;55(3):181-4</RefSource><PMID Version="1">1564476</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Sleep. 1994 Dec;17(8):703-10</RefSource><PMID Version="1">7701181</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 1996 Feb;46(2):388-93</RefSource><PMID Version="1">8614500</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 2005 Nov 8;65(9):1442-6</RefSource><PMID Version="1">16275833</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001143" MajorTopicYN="N">Arousal</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001933" MajorTopicYN="N">Brain Stem</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003704" MajorTopicYN="N">Dementia</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005500" MajorTopicYN="N">Follow-Up Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D019578" MajorTopicYN="N">Multiple System Atrophy</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010300" MajorTopicYN="N">Parkinson Disease</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName><QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020734" MajorTopicYN="N">Parkinsonian Disorders</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017286" MajorTopicYN="N">Polysomnography</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020187" MajorTopicYN="N">REM Sleep Behavior Disorder</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012189" MajorTopicYN="N">Retrospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012894" MajorTopicYN="N">Sleep Stages</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013997" MajorTopicYN="N">Time Factors</DescriptorName></MeshHeading></MeshHeadingList><OtherID Source="NLM">PMC4576326</OtherID><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">dementia</Keyword><Keyword MajorTopicYN="N">hypersomnolence</Keyword><Keyword MajorTopicYN="N">parkinsonism</Keyword><Keyword MajorTopicYN="N">synucleinopathy</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2014</Year><Month>10</Month><Day>20</Day></PubMedPubDate><PubMedPubDate PubStatus="received"><Year>2015</Year><Month>04</Month><Day>23</Day></PubMedPubDate><PubMedPubDate 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