ParkinsonFranceV1, PubMed, Checkpoint, bibRecord, 001487

Magnetic resonance imaging evidence of decreased putamenal iron content in idiopathic Parkinson's disease.

Identifieur interne : 001487 ( PubMed/Checkpoint ); précédent : 001486; suivant : 001488

Magnetic resonance imaging evidence of decreased putamenal iron content in idiopathic Parkinson's disease.

Auteurs : P. Ryvlin [France] ; E. Broussolle ; H. Piollet ; F. Viallet ; Y. Khalfallah ; G. Chazot

Source :

Archives of neurology [ 0003-9942 ] ; 1995.

RBID : pubmed:7763206

English descriptors

KwdEn :
- Adult, Aged, Basal Ganglia (metabolism), Basal Ganglia (pathology), Female, Humans, Iron (metabolism), Magnetic Resonance Imaging, Male, Middle Aged, Parkinson Disease (diagnosis), Parkinson Disease (metabolism), Prospective Studies, Putamen (metabolism), Putamen (pathology).
MESH :
- chemical , metabolism : Iron.
- diagnosis : Parkinson Disease.
- metabolism : Basal Ganglia, Parkinson Disease, Putamen.
- pathology : Basal Ganglia, Putamen.
- Adult, Aged, Female, Humans, Magnetic Resonance Imaging, Male, Middle Aged, Prospective Studies.

Abstract

To determine the changes in basal ganglia iron content associated with various stages of idiopathic Parkinson's disease.

PubMed: 7763206

Affiliations:

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pubmed:7763206

Le document en format XML

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<author><name sortKey="Ryvlin, P" sort="Ryvlin, P" uniqKey="Ryvlin P" first="P" last="Ryvlin">P. Ryvlin</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, Hôpital Neurologique, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Neurology, Hôpital Neurologique, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
<settlement type="city">Lyon</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Broussolle, E" sort="Broussolle, E" uniqKey="Broussolle E" first="E" last="Broussolle">E. Broussolle</name>
</author>
<author><name sortKey="Piollet, H" sort="Piollet, H" uniqKey="Piollet H" first="H" last="Piollet">H. Piollet</name>
</author>
<author><name sortKey="Viallet, F" sort="Viallet, F" uniqKey="Viallet F" first="F" last="Viallet">F. Viallet</name>
</author>
<author><name sortKey="Khalfallah, Y" sort="Khalfallah, Y" uniqKey="Khalfallah Y" first="Y" last="Khalfallah">Y. Khalfallah</name>
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<author><name sortKey="Chazot, G" sort="Chazot, G" uniqKey="Chazot G" first="G" last="Chazot">G. Chazot</name>
</author>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Magnetic resonance imaging evidence of decreased putamenal iron content in idiopathic Parkinson's disease.</title>
<author><name sortKey="Ryvlin, P" sort="Ryvlin, P" uniqKey="Ryvlin P" first="P" last="Ryvlin">P. Ryvlin</name>
<affiliation wicri:level="3"><nlm:affiliation>Department of Neurology, Hôpital Neurologique, Lyon, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Neurology, Hôpital Neurologique, Lyon</wicri:regionArea>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Rhône-Alpes</region>
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<author><name sortKey="Broussolle, E" sort="Broussolle, E" uniqKey="Broussolle E" first="E" last="Broussolle">E. Broussolle</name>
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<author><name sortKey="Piollet, H" sort="Piollet, H" uniqKey="Piollet H" first="H" last="Piollet">H. Piollet</name>
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<author><name sortKey="Viallet, F" sort="Viallet, F" uniqKey="Viallet F" first="F" last="Viallet">F. Viallet</name>
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<author><name sortKey="Khalfallah, Y" sort="Khalfallah, Y" uniqKey="Khalfallah Y" first="Y" last="Khalfallah">Y. Khalfallah</name>
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<author><name sortKey="Chazot, G" sort="Chazot, G" uniqKey="Chazot G" first="G" last="Chazot">G. Chazot</name>
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<series><title level="j">Archives of neurology</title>
<idno type="ISSN">0003-9942</idno>
<imprint><date when="1995" type="published">1995</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Basal Ganglia (metabolism)</term>
<term>Basal Ganglia (pathology)</term>
<term>Female</term>
<term>Humans</term>
<term>Iron (metabolism)</term>
<term>Magnetic Resonance Imaging</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Parkinson Disease (diagnosis)</term>
<term>Parkinson Disease (metabolism)</term>
<term>Prospective Studies</term>
<term>Putamen (metabolism)</term>
<term>Putamen (pathology)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Iron</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Basal Ganglia</term>
<term>Parkinson Disease</term>
<term>Putamen</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Basal Ganglia</term>
<term>Putamen</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Magnetic Resonance Imaging</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prospective Studies</term>
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<front><div type="abstract" xml:lang="en">To determine the changes in basal ganglia iron content associated with various stages of idiopathic Parkinson's disease.</div>
</front>
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<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">7763206</PMID>
<DateCreated><Year>1995</Year>
<Month>06</Month>
<Day>29</Day>
</DateCreated>
<DateCompleted><Year>1995</Year>
<Month>06</Month>
<Day>29</Day>
</DateCompleted>
<DateRevised><Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
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<JournalIssue CitedMedium="Print"><Volume>52</Volume>
<Issue>6</Issue>
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<Month>Jun</Month>
</PubDate>
</JournalIssue>
<Title>Archives of neurology</Title>
<ISOAbbreviation>Arch. Neurol.</ISOAbbreviation>
</Journal>
<ArticleTitle>Magnetic resonance imaging evidence of decreased putamenal iron content in idiopathic Parkinson's disease.</ArticleTitle>
<Pagination><MedlinePgn>583-8</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To determine the changes in basal ganglia iron content associated with various stages of idiopathic Parkinson's disease.</AbstractText>
<AbstractText Label="DESIGN" NlmCategory="METHODS">Prospective magnetic resonance imaging study using a 2-T magnet.</AbstractText>
<AbstractText Label="SETTING" NlmCategory="METHODS">Ambulatory care referral center.</AbstractText>
<AbstractText Label="PATIENTS AND PARTICIPANTS" NlmCategory="METHODS">Forty-five patients suffering from levodopa-responsive Parkinson's disease and 45 age-matched controls.</AbstractText>
<AbstractText Label="MAIN OUTCOME MEASURES" NlmCategory="METHODS">The T2 relaxation time calculated in various regions of the basal ganglia, the duration of Parkinson's disease, and the age of subjects.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Patients with Parkinson's disease exhibited significantly decreased T2 relaxation time in the pars compacta of the substantia nigra compared with controls (P < .01), regardless of disease duration. Patients with a duration of illness above 10 years (n = 12) exhibited significantly increased T2 relaxation time in the anterior and posterior putamen (P < .005 and P < .01, respectively) and in the pallidum (P < .05) compared with age-matched controls. Putamental T2 relaxation time positively correlated with disease duration (P < .05).</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">These results suggest that more complex brain iron changes than those previously reported are associated with idiopathic Parkinson's disease, including increased nigral iron content and decreased putamenal and pallidal iron concentration in patients with a duration of illness above 10 years.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ryvlin</LastName>
<ForeName>P</ForeName>
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<AffiliationInfo><Affiliation>Department of Neurology, Hôpital Neurologique, Lyon, France.</Affiliation>
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<Author ValidYN="Y"><LastName>Piollet</LastName>
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<Author ValidYN="Y"><LastName>Viallet</LastName>
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<Author ValidYN="Y"><LastName>Khalfallah</LastName>
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<Author ValidYN="Y"><LastName>Chazot</LastName>
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<Language>eng</Language>
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<ChemicalList><Chemical><RegistryNumber>E1UOL152H7</RegistryNumber>
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<CitationSubset>AIM</CitationSubset>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
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<MeshHeading><DescriptorName UI="D001479" MajorTopicYN="N">Basal Ganglia</DescriptorName>
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<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
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<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<MeshHeading><DescriptorName UI="D007501" MajorTopicYN="N">Iron</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
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<MeshHeading><DescriptorName UI="D008279" MajorTopicYN="N">Magnetic Resonance Imaging</DescriptorName>
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<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
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<MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010300" MajorTopicYN="N">Parkinson Disease</DescriptorName>
<QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011699" MajorTopicYN="N">Putamen</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName>
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<settlement><li>Lyon</li>
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<name sortKey="Khalfallah, Y" sort="Khalfallah, Y" uniqKey="Khalfallah Y" first="Y" last="Khalfallah">Y. Khalfallah</name>
<name sortKey="Piollet, H" sort="Piollet, H" uniqKey="Piollet H" first="H" last="Piollet">H. Piollet</name>
<name sortKey="Viallet, F" sort="Viallet, F" uniqKey="Viallet F" first="F" last="Viallet">F. Viallet</name>
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<country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Ryvlin, P" sort="Ryvlin, P" uniqKey="Ryvlin P" first="P" last="Ryvlin">P. Ryvlin</name>
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Magnetic resonance imaging evidence of decreased putamenal iron content in idiopathic Parkinson's disease.

Magnetic resonance imaging evidence of decreased putamenal iron content in idiopathic Parkinson's disease.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki