La maladie de Parkinson en France (serveur d'exploration)

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Effect of thalamic stimulation on gait in Parkinson disease.

Identifieur interne : 001454 ( PubMed/Checkpoint ); précédent : 001453; suivant : 001455

Effect of thalamic stimulation on gait in Parkinson disease.

Auteurs : L. Defebvre [France] ; J L Blatt ; S. Blond ; J L Bourriez ; J D Gieu ; A. Destée

Source :

RBID : pubmed:8815855

English descriptors

Abstract

To assess the influence of ventral intermediate thalamic nucleus stimulation on gait in idiopathic Parkinson disease.

PubMed: 8815855


Affiliations:


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pubmed:8815855

Le document en format XML

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<title xml:lang="en">Effect of thalamic stimulation on gait in Parkinson disease.</title>
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<name sortKey="Defebvre, L" sort="Defebvre, L" uniqKey="Defebvre L" first="L" last="Defebvre">L. Defebvre</name>
<affiliation wicri:level="3">
<nlm:affiliation>Department of Gait Analysis, University of Lille, Lille, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Gait Analysis, University of Lille, Lille</wicri:regionArea>
<placeName>
<region type="region">Hauts-de-France</region>
<region type="old region">Nord-Pas-de-Calais</region>
<settlement type="city">Lille</settlement>
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<author>
<name sortKey="Blatt, J L" sort="Blatt, J L" uniqKey="Blatt J" first="J L" last="Blatt">J L Blatt</name>
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<name sortKey="Blond, S" sort="Blond, S" uniqKey="Blond S" first="S" last="Blond">S. Blond</name>
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<name sortKey="Bourriez, J L" sort="Bourriez, J L" uniqKey="Bourriez J" first="J L" last="Bourriez">J L Bourriez</name>
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<name sortKey="Gieu, J D" sort="Gieu, J D" uniqKey="Gieu J" first="J D" last="Gieu">J D Gieu</name>
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<name sortKey="Destee, A" sort="Destee, A" uniqKey="Destee A" first="A" last="Destée">A. Destée</name>
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<term>Humans</term>
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<term>Male</term>
<term>Middle Aged</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Parkinson Disease (surgery)</term>
<term>Pelvis</term>
<term>Posture</term>
<term>Thalamic Nuclei (physiopathology)</term>
<term>Thalamus (surgery)</term>
<term>Walking</term>
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<term>Parkinson Disease</term>
<term>Thalamic Nuclei</term>
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<term>Thalamus</term>
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<term>Ankle Joint</term>
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<div type="abstract" xml:lang="en">To assess the influence of ventral intermediate thalamic nucleus stimulation on gait in idiopathic Parkinson disease.</div>
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<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To assess the influence of ventral intermediate thalamic nucleus stimulation on gait in idiopathic Parkinson disease.</AbstractText>
<AbstractText Label="DESIGN" NlmCategory="METHODS">Clinical and physiological assessments were compared in patients with and without ventral intermediate thalamic nucleus stimulation.</AbstractText>
<AbstractText Label="SETTING" NlmCategory="METHODS">The research clinic of a university department of gait analysis.</AbstractText>
<AbstractText Label="PATIENTS" NlmCategory="METHODS">Seven patients with idiopathic Parkinson disease who had long-term monopolar stimulation of the ventral intermediate thalamic nucleus to control a large-amplitude tremor.</AbstractText>
<AbstractText Label="MAIN OUTCOME MEASURES" NlmCategory="METHODS">Gait kinematic parameters were autonomically recorded using the Vicon optoelectric system for movement analysis. Measures of locomotor displacement (cadence, walking speed, stride and step times, single and double support times, and stride and step lengths) were computed successfully during 2 conditions: stimulation on and off. Traces of ankle joint position were also analyzed for the left and right lower limbs and for the affected and unaffected lower limbs.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">No difference in mean values was observed between the 2 conditions.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">This study seems to confirm that ventral intermediate thalamic nucleus stimulation, effective in reducing tremor, does not modify gait parameters in idiopathic Parkinson disease.</AbstractText>
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