[Myoclonus in the adult: diagnostic approach].
Identifieur interne : 001108 ( PubMed/Checkpoint ); précédent : 001107; suivant : 001109[Myoclonus in the adult: diagnostic approach].
Auteurs : L. Vercueil [France] ; J. KriegerSource :
- Neurophysiologie clinique = Clinical neurophysiology [ 0987-7053 ] ; 2001.
English descriptors
- KwdEn :
- Alzheimer Disease (complications), Brain Stem (physiopathology), Cerebral Cortex (physiopathology), Chorea (diagnosis), Diagnosis, Differential, Dystonia (diagnosis), Electroencephalography, Epilepsies, Myoclonic (classification), Epilepsies, Myoclonic (diagnosis), Epilepsies, Myoclonic (etiology), Evoked Potentials, Somatosensory, Fasciculation (diagnosis), Humans, Magnetoencephalography, Metabolism, Inborn Errors (complications), Myoclonus (diagnosis), Myoclonus (etiology), Myoclonus (genetics), Parkinson Disease (complications), Reflex, Abnormal, Spasm (diagnosis), Spinal Cord (physiopathology), Tics (diagnosis), Tremor (diagnosis).
- MESH :
- classification : Epilepsies, Myoclonic.
- complications : Alzheimer Disease, Metabolism, Inborn Errors, Parkinson Disease.
- diagnosis : Chorea, Dystonia, Epilepsies, Myoclonic, Fasciculation, Myoclonus, Spasm, Tics, Tremor.
- etiology : Epilepsies, Myoclonic, Myoclonus.
- genetics : Myoclonus.
- physiopathology : Brain Stem, Cerebral Cortex, Spinal Cord.
- Diagnosis, Differential, Electroencephalography, Evoked Potentials, Somatosensory, Humans, Magnetoencephalography, Reflex, Abnormal.
Abstract
Myoclonus, defined as shock-like involuntary movement, may be physiological or caused by a very wide variety of hereditary and acquired conditions. Because myoclonus can originate from different disorders and lesions affecting quite varied levels of the central and peripheral nervous systems, it represents from many points of view a diagnostic challenge. Moreover, new entities have been recently individualized, such as cortical tremor, which deserve renewed attention. The aim of this review is to propose a rationale for a diagnostic approach based on clinical and electrophysiological grounds. In this setting, we successively address 1) the clinical features allowing a positive diagnosis of myoclonus; 2) the clinical clues to the etiology; 3) the relevance of the clinical context to the diagnosis; and 4) the contribution of neurophysiology. Differentiating myoclonus from tics, spasm, chorea and dystonia can be difficult, and a careful reappraisal of clinical features allowing precise identification is presented. Moreover, the topographical distribution of myoclonus, the temporal pattern of muscle recruitment, the condition of occurrence and the rhythm of the event, may provide clinical clues relevant to the diagnosis. Myoclonus without associated epilepsy, myoclonus with epilepsy, myoclonus with encephalopathy, parkinsonism and/or dementia represent overlapping clinical categories, although they remain useful for the diagnostic approach. Using electrophysiology (including back-averaging EEG, MEG, SEP, C-reflex studies) to determine the origin of myoclonus may not allow us to focus on the underlying condition. Indeed, in many instances, the myoclonus is cortical in origin, but the pathology is found elsewhere.
PubMed: 11281067
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Krieger</name></author></analytic><series><title level="j">Neurophysiologie clinique = Clinical neurophysiology</title><idno type="ISSN">0987-7053</idno><imprint><date when="2001" type="published">2001</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Alzheimer Disease (complications)</term><term>Brain Stem (physiopathology)</term><term>Cerebral Cortex (physiopathology)</term><term>Chorea (diagnosis)</term><term>Diagnosis, Differential</term><term>Dystonia (diagnosis)</term><term>Electroencephalography</term><term>Epilepsies, Myoclonic (classification)</term><term>Epilepsies, Myoclonic (diagnosis)</term><term>Epilepsies, Myoclonic (etiology)</term><term>Evoked Potentials, Somatosensory</term><term>Fasciculation (diagnosis)</term><term>Humans</term><term>Magnetoencephalography</term><term>Metabolism, Inborn Errors (complications)</term><term>Myoclonus (diagnosis)</term><term>Myoclonus (etiology)</term><term>Myoclonus (genetics)</term><term>Parkinson Disease (complications)</term><term>Reflex, Abnormal</term><term>Spasm (diagnosis)</term><term>Spinal Cord (physiopathology)</term><term>Tics (diagnosis)</term><term>Tremor (diagnosis)</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Epilepsies, Myoclonic</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Alzheimer Disease</term><term>Metabolism, Inborn Errors</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Chorea</term><term>Dystonia</term><term>Epilepsies, Myoclonic</term><term>Fasciculation</term><term>Myoclonus</term><term>Spasm</term><term>Tics</term><term>Tremor</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Epilepsies, Myoclonic</term><term>Myoclonus</term></keywords><keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Myoclonus</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Brain Stem</term><term>Cerebral Cortex</term><term>Spinal Cord</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Diagnosis, Differential</term><term>Electroencephalography</term><term>Evoked Potentials, Somatosensory</term><term>Humans</term><term>Magnetoencephalography</term><term>Reflex, Abnormal</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Myoclonus, defined as shock-like involuntary movement, may be physiological or caused by a very wide variety of hereditary and acquired conditions. Because myoclonus can originate from different disorders and lesions affecting quite varied levels of the central and peripheral nervous systems, it represents from many points of view a diagnostic challenge. Moreover, new entities have been recently individualized, such as cortical tremor, which deserve renewed attention. The aim of this review is to propose a rationale for a diagnostic approach based on clinical and electrophysiological grounds. In this setting, we successively address 1) the clinical features allowing a positive diagnosis of myoclonus; 2) the clinical clues to the etiology; 3) the relevance of the clinical context to the diagnosis; and 4) the contribution of neurophysiology. Differentiating myoclonus from tics, spasm, chorea and dystonia can be difficult, and a careful reappraisal of clinical features allowing precise identification is presented. Moreover, the topographical distribution of myoclonus, the temporal pattern of muscle recruitment, the condition of occurrence and the rhythm of the event, may provide clinical clues relevant to the diagnosis. Myoclonus without associated epilepsy, myoclonus with epilepsy, myoclonus with encephalopathy, parkinsonism and/or dementia represent overlapping clinical categories, although they remain useful for the diagnostic approach. Using electrophysiology (including back-averaging EEG, MEG, SEP, C-reflex studies) to determine the origin of myoclonus may not allow us to focus on the underlying condition. Indeed, in many instances, the myoclonus is cortical in origin, but the pathology is found elsewhere.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">11281067</PMID><DateCreated><Year>2001</Year><Month>04</Month><Day>02</Day></DateCreated><DateCompleted><Year>2001</Year><Month>05</Month><Day>31</Day></DateCompleted><DateRevised><Year>2006</Year><Month>11</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0987-7053</ISSN><JournalIssue CitedMedium="Print"><Volume>31</Volume><Issue>1</Issue><PubDate><Year>2001</Year><Month>Feb</Month></PubDate></JournalIssue><Title>Neurophysiologie clinique = Clinical neurophysiology</Title><ISOAbbreviation>Neurophysiol Clin</ISOAbbreviation></Journal><ArticleTitle>[Myoclonus in the adult: diagnostic approach].</ArticleTitle><Pagination><MedlinePgn>3-17</MedlinePgn></Pagination><Abstract><AbstractText>Myoclonus, defined as shock-like involuntary movement, may be physiological or caused by a very wide variety of hereditary and acquired conditions. Because myoclonus can originate from different disorders and lesions affecting quite varied levels of the central and peripheral nervous systems, it represents from many points of view a diagnostic challenge. Moreover, new entities have been recently individualized, such as cortical tremor, which deserve renewed attention. The aim of this review is to propose a rationale for a diagnostic approach based on clinical and electrophysiological grounds. In this setting, we successively address 1) the clinical features allowing a positive diagnosis of myoclonus; 2) the clinical clues to the etiology; 3) the relevance of the clinical context to the diagnosis; and 4) the contribution of neurophysiology. Differentiating myoclonus from tics, spasm, chorea and dystonia can be difficult, and a careful reappraisal of clinical features allowing precise identification is presented. Moreover, the topographical distribution of myoclonus, the temporal pattern of muscle recruitment, the condition of occurrence and the rhythm of the event, may provide clinical clues relevant to the diagnosis. Myoclonus without associated epilepsy, myoclonus with epilepsy, myoclonus with encephalopathy, parkinsonism and/or dementia represent overlapping clinical categories, although they remain useful for the diagnostic approach. Using electrophysiology (including back-averaging EEG, MEG, SEP, C-reflex studies) to determine the origin of myoclonus may not allow us to focus on the underlying condition. Indeed, in many instances, the myoclonus is cortical in origin, but the pathology is found elsewhere.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Vercueil</LastName><ForeName>L</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>Service de neurologie, Hôpitaux universitaires de Grenoble, 38700 La Tronche, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Krieger</LastName><ForeName>J</ForeName><Initials>J</Initials></Author></AuthorList><Language>fre</Language><PublicationTypeList><PublicationType UI="D004740">English Abstract</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><VernacularTitle>Les myoclonies chez l'adulte: démarche diagnostique.</VernacularTitle></Article><MedlineJournalInfo><Country>France</Country><MedlineTA>Neurophysiol Clin</MedlineTA><NlmUniqueID>8804532</NlmUniqueID><ISSNLinking>0987-7053</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000544" MajorTopicYN="N">Alzheimer Disease</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001933" MajorTopicYN="N">Brain Stem</DescriptorName><QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002540" MajorTopicYN="N">Cerebral Cortex</DescriptorName><QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002819" MajorTopicYN="N">Chorea</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003937" MajorTopicYN="N">Diagnosis, Differential</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004421" MajorTopicYN="N">Dystonia</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D004569" MajorTopicYN="N">Electroencephalography</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004831" MajorTopicYN="N">Epilepsies, Myoclonic</DescriptorName><QualifierName UI="Q000145" MajorTopicYN="N">classification</QualifierName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005073" MajorTopicYN="N">Evoked Potentials, Somatosensory</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005207" MajorTopicYN="N">Fasciculation</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015225" MajorTopicYN="N">Magnetoencephalography</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008661" MajorTopicYN="N">Metabolism, Inborn Errors</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009207" MajorTopicYN="N">Myoclonus</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName><QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010300" MajorTopicYN="N">Parkinson Disease</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="N">complications</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012021" MajorTopicYN="N">Reflex, Abnormal</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D013035" MajorTopicYN="N">Spasm</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D013116" MajorTopicYN="N">Spinal Cord</DescriptorName><QualifierName UI="Q000503" MajorTopicYN="N">physiopathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D020323" MajorTopicYN="N">Tics</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014202" MajorTopicYN="N">Tremor</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName></MeshHeading></MeshHeadingList><NumberOfReferences>94</NumberOfReferences></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2001</Year><Month>4</Month><Day>3</Day><Hour>10</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2001</Year><Month>6</Month><Day>2</Day><Hour>10</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2001</Year><Month>4</Month><Day>3</Day><Hour>10</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">11281067</ArticleId><ArticleId IdType="pii">S0987705300002446</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>France</li></country><region><li>Auvergne-Rhône-Alpes</li><li>Rhône-Alpes</li></region><settlement><li>La Tronche</li></settlement></list><tree><noCountry><name sortKey="Krieger, J" sort="Krieger, J" uniqKey="Krieger J" first="J" last="Krieger">J. Krieger</name></noCountry><country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Vercueil, L" sort="Vercueil, L" uniqKey="Vercueil L" first="L" last="Vercueil">L. Vercueil</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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