La maladie de Parkinson en France (serveur d'exploration)

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Postural sway and effect of levodopa in early Parkinson's disease.

Identifieur interne : 000B96 ( PubMed/Checkpoint ); précédent : 000B95; suivant : 000B97

Postural sway and effect of levodopa in early Parkinson's disease.

Auteurs : Anne Beuter [France] ; Roberto Hernández ; Robert Rigal ; Julien Modolo ; Pierre J. Blanchet

Source :

RBID : pubmed:18380279

English descriptors

Abstract

To characterize postural stability control and levodopa responsiveness in early Parkinson's disease (PD).

PubMed: 18380279


Affiliations:


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pubmed:18380279

Le document en format XML

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<title xml:lang="en">Postural sway and effect of levodopa in early Parkinson's disease.</title>
<author>
<name sortKey="Beuter, Anne" sort="Beuter, Anne" uniqKey="Beuter A" first="Anne" last="Beuter">Anne Beuter</name>
<affiliation wicri:level="3">
<nlm:affiliation>Institut de Cognitique, Université Victor Segalen Bordeaux 2, Bordeaux, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut de Cognitique, Université Victor Segalen Bordeaux 2, Bordeaux</wicri:regionArea>
<placeName>
<region type="region">Nouvelle-Aquitaine</region>
<region type="old region">Aquitaine</region>
<settlement type="city">Bordeaux</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Hernandez, Roberto" sort="Hernandez, Roberto" uniqKey="Hernandez R" first="Roberto" last="Hernández">Roberto Hernández</name>
</author>
<author>
<name sortKey="Rigal, Robert" sort="Rigal, Robert" uniqKey="Rigal R" first="Robert" last="Rigal">Robert Rigal</name>
</author>
<author>
<name sortKey="Modolo, Julien" sort="Modolo, Julien" uniqKey="Modolo J" first="Julien" last="Modolo">Julien Modolo</name>
</author>
<author>
<name sortKey="Blanchet, Pierre J" sort="Blanchet, Pierre J" uniqKey="Blanchet P" first="Pierre J" last="Blanchet">Pierre J. Blanchet</name>
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<title xml:lang="en">Postural sway and effect of levodopa in early Parkinson's disease.</title>
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<name sortKey="Beuter, Anne" sort="Beuter, Anne" uniqKey="Beuter A" first="Anne" last="Beuter">Anne Beuter</name>
<affiliation wicri:level="3">
<nlm:affiliation>Institut de Cognitique, Université Victor Segalen Bordeaux 2, Bordeaux, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Institut de Cognitique, Université Victor Segalen Bordeaux 2, Bordeaux</wicri:regionArea>
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<region type="region">Nouvelle-Aquitaine</region>
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<name sortKey="Hernandez, Roberto" sort="Hernandez, Roberto" uniqKey="Hernandez R" first="Roberto" last="Hernández">Roberto Hernández</name>
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<author>
<name sortKey="Rigal, Robert" sort="Rigal, Robert" uniqKey="Rigal R" first="Robert" last="Rigal">Robert Rigal</name>
</author>
<author>
<name sortKey="Modolo, Julien" sort="Modolo, Julien" uniqKey="Modolo J" first="Julien" last="Modolo">Julien Modolo</name>
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<name sortKey="Blanchet, Pierre J" sort="Blanchet, Pierre J" uniqKey="Blanchet P" first="Pierre J" last="Blanchet">Pierre J. Blanchet</name>
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<series>
<title level="j">The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques</title>
<idno type="ISSN">0317-1671</idno>
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<date when="2008" type="published">2008</date>
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<term>Aged</term>
<term>Antiparkinson Agents (therapeutic use)</term>
<term>Dopamine (physiology)</term>
<term>Female</term>
<term>Humans</term>
<term>Levodopa (therapeutic use)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Parkinson Disease (drug therapy)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Postural Balance (drug effects)</term>
<term>Postural Balance (physiology)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="physiology" xml:lang="en">
<term>Dopamine</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en">
<term>Antiparkinson Agents</term>
<term>Levodopa</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en">
<term>Postural Balance</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en">
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en">
<term>Postural Balance</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en">
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
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<front>
<div type="abstract" xml:lang="en">To characterize postural stability control and levodopa responsiveness in early Parkinson's disease (PD).</div>
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<Year>2008</Year>
<Month>04</Month>
<Day>02</Day>
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<Year>2008</Year>
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<Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
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<ISSN IssnType="Print">0317-1671</ISSN>
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<Volume>35</Volume>
<Issue>1</Issue>
<PubDate>
<Year>2008</Year>
<Month>Mar</Month>
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<Title>The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques</Title>
<ISOAbbreviation>Can J Neurol Sci</ISOAbbreviation>
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<ArticleTitle>Postural sway and effect of levodopa in early Parkinson's disease.</ArticleTitle>
<Pagination>
<MedlinePgn>65-8</MedlinePgn>
</Pagination>
<Abstract>
<AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">To characterize postural stability control and levodopa responsiveness in early Parkinson's disease (PD).</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">Postural sway was studied during quiet stance in ten patients within six years of PD onset, both before (OFF) and after (ON) regular oral levodopa dosing. Postural sway was recorded using a force platform during 30 sec with eyes open, and six dependent variables were examined.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">Mild baseline subclinical changes in postural sway were recorded in our patients. Clear benefit was observed in five out of six characteristics (mean sway, transversal sway, sagittal sway, sway intensity, and sway area) in the ON condition.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Postural control mechanisms are affected early in PD and modulated by dopamine.</AbstractText>
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<LastName>Beuter</LastName>
<ForeName>Anne</ForeName>
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<Affiliation>Institut de Cognitique, Université Victor Segalen Bordeaux 2, Bordeaux, France.</Affiliation>
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<DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
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<DescriptorName UI="D007980" MajorTopicYN="N">Levodopa</DescriptorName>
<QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName>
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