Subthalamic nucleus stimulation affects orbitofrontal cortex in facial emotion recognition: a PET study.
Identifieur interne : 000B83 ( PubMed/Checkpoint ); précédent : 000B82; suivant : 000B84Subthalamic nucleus stimulation affects orbitofrontal cortex in facial emotion recognition: a PET study.
Auteurs : F. Le Jeune [France] ; J. Péron ; I. Biseul ; S. Fournier ; P. Sauleau ; S. Drapier ; C. Haegelen ; D. Drapier ; B. Millet ; E. Garin ; J-Y Herry ; C-H Malbert ; M. VérinSource :
- Brain : a journal of neurology [ 1460-2156 ] ; 2008.
English descriptors
- KwdEn :
- Case-Control Studies, Deep Brain Stimulation (adverse effects), Deep Brain Stimulation (methods), Facial Expression, Fear, Female, Fluorodeoxyglucose F18, Frontal Lobe (diagnostic imaging), Frontal Lobe (physiology), Glucose (metabolism), Humans, Male, Middle Aged, Neuropsychological Tests, Parkinson Disease (metabolism), Parkinson Disease (psychology), Parkinson Disease (therapy), Positron-Emission Tomography, Recognition (Psychology), Statistics, Nonparametric, Subthalamic Nucleus (diagnostic imaging), Subthalamic Nucleus (physiology).
- MESH :
- chemical , metabolism : Glucose.
- chemical : Fluorodeoxyglucose F18.
- adverse effects : Deep Brain Stimulation.
- diagnostic imaging : Frontal Lobe, Subthalamic Nucleus.
- metabolism : Parkinson Disease.
- methods : Deep Brain Stimulation.
- physiology : Frontal Lobe, Subthalamic Nucleus.
- psychology : Parkinson Disease.
- therapy : Parkinson Disease.
- Case-Control Studies, Facial Expression, Fear, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Positron-Emission Tomography, Recognition (Psychology), Statistics, Nonparametric.
Abstract
Deep brain stimulation (DBS) of the bilateral subthalamic nucleus (STN) in Parkinson's disease is thought to produce adverse events such as emotional disorders, and in a recent study, we found fear recognition to be impaired as a result. These changes have been attributed to disturbance of the STN's limbic territory and would appear to confirm that the negative emotion recognition network passes through the STN. In addition, it is now widely acknowledged that damage to the orbitofrontal cortex (OFC), especially the right side, can result in impaired recognition of facial emotions (RFE). In this context, we hypothesized that this reduced recognition of fear is correlated with modifications in the cerebral glucose metabolism of the right OFC. The objective of the present study was first, to reinforce our previous results by demonstrating reduced fear recognition in our Parkinson's disease patient group following STN DBS and, second, to correlate these emotional performances with glucose metabolism using (18)FDG-PET. The (18)FDG-PET and RFE tasks were both performed by a cohort of 13 Parkinson's disease patients 3 months before and 3 months after surgery for STN DBS. As predicted, we observed a significant reduction in fear recognition following surgery and obtained a positive correlation between these neuropsychological results and changes in glucose metabolism, especially in the right OFC. These results confirm the role of the STN as a key basal ganglia structure in limbic circuits.
DOI: 10.1093/brain/awn084
PubMed: 18490359
Affiliations:
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Links to Exploration step
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Le Jeune</name><affiliation wicri:level="3"><nlm:affiliation>Service de Médecine Nucléaire, Centre Eugène Marquis, rue de la Bataille Flandres Dunkerque, 35042 Rennes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Service de Médecine Nucléaire, Centre Eugène Marquis, rue de la Bataille Flandres Dunkerque, 35042 Rennes</wicri:regionArea><placeName><region type="region" nuts="2">Région Bretagne</region><settlement type="city">Rennes</settlement></placeName></affiliation></author><author><name sortKey="Peron, J" sort="Peron, J" uniqKey="Peron J" first="J" last="Péron">J. Péron</name></author><author><name sortKey="Biseul, I" sort="Biseul, I" uniqKey="Biseul I" first="I" last="Biseul">I. Biseul</name></author><author><name sortKey="Fournier, S" sort="Fournier, S" uniqKey="Fournier S" first="S" last="Fournier">S. Fournier</name></author><author><name sortKey="Sauleau, P" sort="Sauleau, P" uniqKey="Sauleau P" first="P" last="Sauleau">P. 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Vérin</name></author></analytic><series><title level="j">Brain : a journal of neurology</title><idno type="eISSN">1460-2156</idno><imprint><date when="2008" type="published">2008</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Case-Control Studies</term><term>Deep Brain Stimulation (adverse effects)</term><term>Deep Brain Stimulation (methods)</term><term>Facial Expression</term><term>Fear</term><term>Female</term><term>Fluorodeoxyglucose F18</term><term>Frontal Lobe (diagnostic imaging)</term><term>Frontal Lobe (physiology)</term><term>Glucose (metabolism)</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Neuropsychological Tests</term><term>Parkinson Disease (metabolism)</term><term>Parkinson Disease (psychology)</term><term>Parkinson Disease (therapy)</term><term>Positron-Emission Tomography</term><term>Recognition (Psychology)</term><term>Statistics, Nonparametric</term><term>Subthalamic Nucleus (diagnostic imaging)</term><term>Subthalamic Nucleus (physiology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Glucose</term></keywords><keywords scheme="MESH" type="chemical" xml:lang="en"><term>Fluorodeoxyglucose F18</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Deep Brain Stimulation</term></keywords><keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Frontal Lobe</term><term>Subthalamic Nucleus</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Deep Brain Stimulation</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Frontal Lobe</term><term>Subthalamic Nucleus</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Case-Control Studies</term><term>Facial Expression</term><term>Fear</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Neuropsychological Tests</term><term>Positron-Emission Tomography</term><term>Recognition (Psychology)</term><term>Statistics, Nonparametric</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Deep brain stimulation (DBS) of the bilateral subthalamic nucleus (STN) in Parkinson's disease is thought to produce adverse events such as emotional disorders, and in a recent study, we found fear recognition to be impaired as a result. These changes have been attributed to disturbance of the STN's limbic territory and would appear to confirm that the negative emotion recognition network passes through the STN. In addition, it is now widely acknowledged that damage to the orbitofrontal cortex (OFC), especially the right side, can result in impaired recognition of facial emotions (RFE). In this context, we hypothesized that this reduced recognition of fear is correlated with modifications in the cerebral glucose metabolism of the right OFC. The objective of the present study was first, to reinforce our previous results by demonstrating reduced fear recognition in our Parkinson's disease patient group following STN DBS and, second, to correlate these emotional performances with glucose metabolism using (18)FDG-PET. The (18)FDG-PET and RFE tasks were both performed by a cohort of 13 Parkinson's disease patients 3 months before and 3 months after surgery for STN DBS. As predicted, we observed a significant reduction in fear recognition following surgery and obtained a positive correlation between these neuropsychological results and changes in glucose metabolism, especially in the right OFC. These results confirm the role of the STN as a key basal ganglia structure in limbic circuits.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">18490359</PMID><DateCreated><Year>2008</Year><Month>06</Month><Day>04</Day></DateCreated><DateCompleted><Year>2008</Year><Month>11</Month><Day>13</Day></DateCompleted><DateRevised><Year>2016</Year><Month>11</Month><Day>24</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1460-2156</ISSN><JournalIssue CitedMedium="Internet"><Volume>131</Volume><Issue>Pt 6</Issue><PubDate><Year>2008</Year><Month>Jun</Month></PubDate></JournalIssue><Title>Brain : a journal of neurology</Title><ISOAbbreviation>Brain</ISOAbbreviation></Journal><ArticleTitle>Subthalamic nucleus stimulation affects orbitofrontal cortex in facial emotion recognition: a PET study.</ArticleTitle><Pagination><MedlinePgn>1599-608</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1093/brain/awn084</ELocationID><Abstract><AbstractText>Deep brain stimulation (DBS) of the bilateral subthalamic nucleus (STN) in Parkinson's disease is thought to produce adverse events such as emotional disorders, and in a recent study, we found fear recognition to be impaired as a result. These changes have been attributed to disturbance of the STN's limbic territory and would appear to confirm that the negative emotion recognition network passes through the STN. In addition, it is now widely acknowledged that damage to the orbitofrontal cortex (OFC), especially the right side, can result in impaired recognition of facial emotions (RFE). In this context, we hypothesized that this reduced recognition of fear is correlated with modifications in the cerebral glucose metabolism of the right OFC. The objective of the present study was first, to reinforce our previous results by demonstrating reduced fear recognition in our Parkinson's disease patient group following STN DBS and, second, to correlate these emotional performances with glucose metabolism using (18)FDG-PET. The (18)FDG-PET and RFE tasks were both performed by a cohort of 13 Parkinson's disease patients 3 months before and 3 months after surgery for STN DBS. As predicted, we observed a significant reduction in fear recognition following surgery and obtained a positive correlation between these neuropsychological results and changes in glucose metabolism, especially in the right OFC. These results confirm the role of the STN as a key basal ganglia structure in limbic circuits.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Le Jeune</LastName><ForeName>F</ForeName><Initials>F</Initials><AffiliationInfo><Affiliation>Service de Médecine Nucléaire, Centre Eugène Marquis, rue de la Bataille Flandres Dunkerque, 35042 Rennes, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Péron</LastName><ForeName>J</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Biseul</LastName><ForeName>I</ForeName><Initials>I</Initials></Author><Author ValidYN="Y"><LastName>Fournier</LastName><ForeName>S</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Sauleau</LastName><ForeName>P</ForeName><Initials>P</Initials></Author><Author ValidYN="Y"><LastName>Drapier</LastName><ForeName>S</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Haegelen</LastName><ForeName>C</ForeName><Initials>C</Initials></Author><Author ValidYN="Y"><LastName>Drapier</LastName><ForeName>D</ForeName><Initials>D</Initials></Author><Author ValidYN="Y"><LastName>Millet</LastName><ForeName>B</ForeName><Initials>B</Initials></Author><Author ValidYN="Y"><LastName>Garin</LastName><ForeName>E</ForeName><Initials>E</Initials></Author><Author ValidYN="Y"><LastName>Herry</LastName><ForeName>J-Y</ForeName><Initials>JY</Initials></Author><Author ValidYN="Y"><LastName>Malbert</LastName><ForeName>C-H</ForeName><Initials>CH</Initials></Author><Author ValidYN="Y"><LastName>Vérin</LastName><ForeName>M</ForeName><Initials>M</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D003160">Comparative Study</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2008</Year><Month>05</Month><Day>18</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Brain</MedlineTA><NlmUniqueID>0372537</NlmUniqueID><ISSNLinking>0006-8950</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0Z5B2CJX4D</RegistryNumber><NameOfSubstance UI="D019788">Fluorodeoxyglucose F18</NameOfSubstance></Chemical><Chemical><RegistryNumber>IY9XDZ35W2</RegistryNumber><NameOfSubstance UI="D005947">Glucose</NameOfSubstance></Chemical></ChemicalList><CitationSubset>AIM</CitationSubset><CitationSubset>IM</CitationSubset><CommentsCorrectionsList><CommentsCorrections RefType="Cites"><RefSource>Cortex. 1976 Dec;12(4):313-24</RefSource><PMID Version="1">1009768</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neuropsychologia. 1971 Mar;9(1):97-113</RefSource><PMID Version="1">5146491</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Brain Res. 1990 Apr 9;513(1):43-59</RefSource><PMID Version="1">2350684</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Acta Neurol Belg. 1990;90(4):207-17</RefSource><PMID Version="1">2124031</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Prog Brain Res. 1990;85:119-46</RefSource><PMID Version="1">2094891</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 1992;7(1):2-13</RefSource><PMID Version="1">1557062</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Neurol Neurosurg Psychiatry. 1992 Mar;55(3):181-4</RefSource><PMID Version="1">1564476</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Brain Res Brain Res Rev. 1995 Jan;20(1):128-54</RefSource><PMID Version="1">7711765</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Lancet. 1995 Nov 25;346(8987):1383-7</RefSource><PMID Version="1">7475819</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neuropsychologia. 1996 Apr;34(4):247-61</RefSource><PMID Version="1">8657356</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Neurosci. 1996 Dec 1;16(23):7678-87</RefSource><PMID Version="1">8922424</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Brain Res Brain Res Rev. 1997 Feb;23(1-2):62-78</RefSource><PMID Version="1">9063587</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neuropsychology. 1998 Apr;12(2):253-8</RefSource><PMID Version="1">9556771</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Proc Biol Sci. 1998 Oct 22;265(1409):1927-31</RefSource><PMID Version="1">9821359</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neuroscience. 2005;131(2):523-34</RefSource><PMID Version="1">15708493</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neuropsychologia. 2005;43(7):1054-9</RefSource><PMID Version="1">15769491</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Parkinsonism Relat Disord. 2006 Jun;12(5):265-72</RefSource><PMID Version="1">16621661</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Neurol. 2006 Aug;253(8):1083-91</RefSource><PMID Version="1">16607469</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neuroimage. 2007 Feb 1;34(3):905-23</RefSource><PMID Version="1">17126037</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Behav Cogn Neurosci Rev. 2002 Mar;1(1):21-62</RefSource><PMID Version="1">17715585</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Neurol. 1999 Sep;246 Suppl 2:II42-5</RefSource><PMID Version="1">10526001</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Psychopharmacology (Berl). 1999 Dec;147(3):335-8</RefSource><PMID Version="1">10639695</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Brain Cogn. 2000 Apr;42(3):324-47</RefSource><PMID Version="1">10753483</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 2000 Aug 8;55(3):411-8</RefSource><PMID Version="1">10932277</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Brain. 2000 Oct;123 ( Pt 10):2091-108</RefSource><PMID Version="1">11004126</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 2000;55(12 Suppl 6):S40-4</RefSource><PMID Version="1">11188974</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Rev Neurol (Paris). 2001 May;157(5):567-71</RefSource><PMID Version="1">11438780</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Brain. 2002 Mar;125(Pt 3):575-83</RefSource><PMID Version="1">11872614</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2002;17 Suppl 3:S188-97</RefSource><PMID Version="1">11948776</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Curr Opin Neurobiol. 2002 Apr;12(2):169-77</RefSource><PMID Version="1">12015233</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Neurol Neurosurg Psychiatry. 2002 Jun;72(6):701-7</RefSource><PMID Version="1">12023409</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Brain. 2002 Sep;125(Pt 9):1995-2004</RefSource><PMID Version="1">12183345</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 2002 Nov 12;59(9):1425-7</RefSource><PMID Version="1">12427896</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Mov Disord. 2003 Jan;18(1):41-8</RefSource><PMID Version="1">12518299</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neuroimage. 2003 Jul;19(3):601-12</RefSource><PMID Version="1">12880791</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Emotion. 2002 Mar;2(1):23-51</RefSource><PMID Version="1">12899365</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Ann Neurol. 2003 Oct;54(4):445-50</RefSource><PMID Version="1">14520655</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neuropsychologia. 2004;42(2):239-50</RefSource><PMID Version="1">14644109</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Cereb Blood Flow Metab. 2004 Jan;24(1):7-16</RefSource><PMID Version="1">14688612</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Neurol Neurosurg Psychiatry. 2004 Feb;75(2):202-8</RefSource><PMID Version="1">14742588</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>J Neurol Neurosurg Psychiatry. 2004 Apr;75(4):648-50</RefSource><PMID Version="1">15026519</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Neurology. 1967 May;17(5):427-42</RefSource><PMID Version="1">6067254</PMID></CommentsCorrections><CommentsCorrections RefType="Cites"><RefSource>Br J Psychiatry. 1979 Apr;134:382-9</RefSource><PMID Version="1">444788</PMID></CommentsCorrections></CommentsCorrectionsList><MeshHeadingList><MeshHeading><DescriptorName UI="D016022" MajorTopicYN="N">Case-Control Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D046690" MajorTopicYN="N">Deep Brain Stimulation</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005149" MajorTopicYN="Y">Facial Expression</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005239" MajorTopicYN="N">Fear</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D019788" MajorTopicYN="N">Fluorodeoxyglucose F18</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005625" MajorTopicYN="N">Frontal Lobe</DescriptorName><QualifierName UI="Q000000981" MajorTopicYN="Y">diagnostic imaging</QualifierName><QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005947" MajorTopicYN="N">Glucose</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009483" MajorTopicYN="N">Neuropsychological Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010300" MajorTopicYN="N">Parkinson Disease</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName><QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName><QualifierName UI="Q000628" MajorTopicYN="Y">therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D049268" MajorTopicYN="N">Positron-Emission Tomography</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D021641" MajorTopicYN="Y">Recognition (Psychology)</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018709" MajorTopicYN="N">Statistics, Nonparametric</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D020531" MajorTopicYN="N">Subthalamic Nucleus</DescriptorName><QualifierName UI="Q000000981" MajorTopicYN="Y">diagnostic imaging</QualifierName><QualifierName UI="Q000502" MajorTopicYN="N">physiology</QualifierName></MeshHeading></MeshHeadingList><OtherID Source="NLM">PMC2408938</OtherID></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2008</Year><Month>5</Month><Day>21</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2008</Year><Month>11</Month><Day>14</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2008</Year><Month>5</Month><Day>21</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">18490359</ArticleId><ArticleId IdType="pii">awn084</ArticleId><ArticleId IdType="doi">10.1093/brain/awn084</ArticleId><ArticleId IdType="pmc">PMC2408938</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>France</li></country><region><li>Région Bretagne</li></region><settlement><li>Rennes</li></settlement></list><tree><noCountry><name sortKey="Biseul, I" sort="Biseul, I" uniqKey="Biseul I" first="I" last="Biseul">I. Biseul</name><name sortKey="Drapier, D" sort="Drapier, D" uniqKey="Drapier D" first="D" last="Drapier">D. Drapier</name><name sortKey="Drapier, S" sort="Drapier, S" uniqKey="Drapier S" first="S" last="Drapier">S. Drapier</name><name sortKey="Fournier, S" sort="Fournier, S" uniqKey="Fournier S" first="S" last="Fournier">S. Fournier</name><name sortKey="Garin, E" sort="Garin, E" uniqKey="Garin E" first="E" last="Garin">E. Garin</name><name sortKey="Haegelen, C" sort="Haegelen, C" uniqKey="Haegelen C" first="C" last="Haegelen">C. Haegelen</name><name sortKey="Herry, J Y" sort="Herry, J Y" uniqKey="Herry J" first="J-Y" last="Herry">J-Y Herry</name><name sortKey="Malbert, C H" sort="Malbert, C H" uniqKey="Malbert C" first="C-H" last="Malbert">C-H Malbert</name><name sortKey="Millet, B" sort="Millet, B" uniqKey="Millet B" first="B" last="Millet">B. Millet</name><name sortKey="Peron, J" sort="Peron, J" uniqKey="Peron J" first="J" last="Péron">J. Péron</name><name sortKey="Sauleau, P" sort="Sauleau, P" uniqKey="Sauleau P" first="P" last="Sauleau">P. Sauleau</name><name sortKey="Verin, M" sort="Verin, M" uniqKey="Verin M" first="M" last="Vérin">M. Vérin</name></noCountry><country name="France"><region name="Région Bretagne"><name sortKey="Le Jeune, F" sort="Le Jeune, F" uniqKey="Le Jeune F" first="F" last="Le Jeune">F. Le Jeune</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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