ParkinsonFranceV1, PubMed, Checkpoint, bibRecord, 000995

Neurodegenerative dementia and parkinsonism.

Identifieur interne : 000995 ( PubMed/Checkpoint ); précédent : 000994; suivant : 000996

Neurodegenerative dementia and parkinsonism.

Auteurs : A. Gabelle [France] ; F. Portet ; C. Berr ; J. Touchon

Source :

The journal of nutrition, health & aging [ 1760-4788 ] ; 2010.

RBID : pubmed:20082052

English descriptors

KwdEn :
- Aged, Amyloid beta-Peptides (genetics), Amyloid beta-Peptides (metabolism), Brain (metabolism), Brain (pathology), Brain Chemistry, DNA-Binding Proteins (genetics), DNA-Binding Proteins (metabolism), Dementia (classification), Dementia (diagnosis), Dementia (genetics), Dementia (metabolism), Diagnosis, Differential, Humans, Parkinson Disease (classification), Parkinson Disease (diagnosis), Parkinson Disease (genetics), Parkinson Disease (metabolism), alpha-Synuclein (genetics), alpha-Synuclein (metabolism), tau Proteins (genetics), tau Proteins (metabolism).
MESH :
- chemical , genetics : Amyloid beta-Peptides, DNA-Binding Proteins, alpha-Synuclein, tau Proteins.
- chemical , metabolism : Amyloid beta-Peptides, DNA-Binding Proteins, alpha-Synuclein, tau Proteins.
- classification : Dementia, Parkinson Disease.
- diagnosis : Dementia, Parkinson Disease.
- genetics : Dementia, Parkinson Disease.
- metabolism : Brain, Dementia, Parkinson Disease.
- pathology : Brain.
- Aged, Brain Chemistry, Diagnosis, Differential, Humans.

Abstract

Dementia and Parkinsonism are two major neurodegenerative disorders. Accurate diagnosis can be difficult when patients have both syndromes because of a wide range of etiologies.

PubMed: 20082052

Affiliations:

France

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to stream PubMed, to step Corpus: 000B26
to stream PubMed, to step Curation: 000A86

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pubmed:20082052

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Neurodegenerative dementia and parkinsonism.</title>
<author><name sortKey="Gabelle, A" sort="Gabelle, A" uniqKey="Gabelle A" first="A" last="Gabelle">A. Gabelle</name>
<affiliation wicri:level="1"><nlm:affiliation>Service de Neurologie, CHRU Montpellier, Hopital Gui de Chauliac, Montpellier Cedex 5, France. a-gabelle@chu-montpellier.fr</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neurologie, CHRU Montpellier, Hopital Gui de Chauliac, Montpellier Cedex 5</wicri:regionArea>
<wicri:noRegion>Montpellier Cedex 5</wicri:noRegion>
<wicri:noRegion>Montpellier Cedex 5</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Portet, F" sort="Portet, F" uniqKey="Portet F" first="F" last="Portet">F. Portet</name>
</author>
<author><name sortKey="Berr, C" sort="Berr, C" uniqKey="Berr C" first="C" last="Berr">C. Berr</name>
</author>
<author><name sortKey="Touchon, J" sort="Touchon, J" uniqKey="Touchon J" first="J" last="Touchon">J. Touchon</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Neurodegenerative dementia and parkinsonism.</title>
<author><name sortKey="Gabelle, A" sort="Gabelle, A" uniqKey="Gabelle A" first="A" last="Gabelle">A. Gabelle</name>
<affiliation wicri:level="1"><nlm:affiliation>Service de Neurologie, CHRU Montpellier, Hopital Gui de Chauliac, Montpellier Cedex 5, France. a-gabelle@chu-montpellier.fr</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neurologie, CHRU Montpellier, Hopital Gui de Chauliac, Montpellier Cedex 5</wicri:regionArea>
<wicri:noRegion>Montpellier Cedex 5</wicri:noRegion>
<wicri:noRegion>Montpellier Cedex 5</wicri:noRegion>
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<author><name sortKey="Portet, F" sort="Portet, F" uniqKey="Portet F" first="F" last="Portet">F. Portet</name>
</author>
<author><name sortKey="Berr, C" sort="Berr, C" uniqKey="Berr C" first="C" last="Berr">C. Berr</name>
</author>
<author><name sortKey="Touchon, J" sort="Touchon, J" uniqKey="Touchon J" first="J" last="Touchon">J. Touchon</name>
</author>
</analytic>
<series><title level="j">The journal of nutrition, health & aging</title>
<idno type="eISSN">1760-4788</idno>
<imprint><date when="2010" type="published">2010</date>
</imprint>
</series>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Amyloid beta-Peptides (genetics)</term>
<term>Amyloid beta-Peptides (metabolism)</term>
<term>Brain (metabolism)</term>
<term>Brain (pathology)</term>
<term>Brain Chemistry</term>
<term>DNA-Binding Proteins (genetics)</term>
<term>DNA-Binding Proteins (metabolism)</term>
<term>Dementia (classification)</term>
<term>Dementia (diagnosis)</term>
<term>Dementia (genetics)</term>
<term>Dementia (metabolism)</term>
<term>Diagnosis, Differential</term>
<term>Humans</term>
<term>Parkinson Disease (classification)</term>
<term>Parkinson Disease (diagnosis)</term>
<term>Parkinson Disease (genetics)</term>
<term>Parkinson Disease (metabolism)</term>
<term>alpha-Synuclein (genetics)</term>
<term>alpha-Synuclein (metabolism)</term>
<term>tau Proteins (genetics)</term>
<term>tau Proteins (metabolism)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Amyloid beta-Peptides</term>
<term>DNA-Binding Proteins</term>
<term>alpha-Synuclein</term>
<term>tau Proteins</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Amyloid beta-Peptides</term>
<term>DNA-Binding Proteins</term>
<term>alpha-Synuclein</term>
<term>tau Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Dementia</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Dementia</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Dementia</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Brain</term>
<term>Dementia</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Brain</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Brain Chemistry</term>
<term>Diagnosis, Differential</term>
<term>Humans</term>
</keywords>
</textClass>
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<front><div type="abstract" xml:lang="en">Dementia and Parkinsonism are two major neurodegenerative disorders. Accurate diagnosis can be difficult when patients have both syndromes because of a wide range of etiologies.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">20082052</PMID>
<DateCreated><Year>2010</Year>
<Month>01</Month>
<Day>18</Day>
</DateCreated>
<DateCompleted><Year>2010</Year>
<Month>04</Month>
<Day>06</Day>
</DateCompleted>
<DateRevised><Year>2016</Year>
<Month>08</Month>
<Day>26</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1760-4788</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>14</Volume>
<Issue>1</Issue>
<PubDate><Year>2010</Year>
<Month>Jan</Month>
</PubDate>
</JournalIssue>
<Title>The journal of nutrition, health & aging</Title>
<ISOAbbreviation>J Nutr Health Aging</ISOAbbreviation>
</Journal>
<ArticleTitle>Neurodegenerative dementia and parkinsonism.</ArticleTitle>
<Pagination><MedlinePgn>37-44</MedlinePgn>
</Pagination>
<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Dementia and Parkinsonism are two major neurodegenerative disorders. Accurate diagnosis can be difficult when patients have both syndromes because of a wide range of etiologies.</AbstractText>
<AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">To improve clinical diagnosis, we propose a disease classification based on the pathological proteins which are involved in the neuropathological disease process.</AbstractText>
<AbstractText Label="DESIGN" NlmCategory="METHODS">Four neuropathological classes are proposed based on four major proteins, tau, A beta, alpha -synuclein and TDP43 : 1/ Tauopathy and amyloidopathy with possible Parkinsonism, 2/ Tauopathy with predominant Parkinsonism, 3/ Synucleinopathies with cognitive impairment/dementia and 4/ The TAR DNA binding protein 43 (TDP-43). This classification raises certain questions in clinical practice due to intriguing overlaps between clinical presentations despite the same pathological protein being involved.</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">The development of molecular and pathological protein research in neurodegenerative disorders can help classify the clinical association of dementia and Parkinsonism and improve therapeutic strategies against proteins involved in the degenerative process.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Gabelle</LastName>
<ForeName>A</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Service de Neurologie, CHRU Montpellier, Hopital Gui de Chauliac, Montpellier Cedex 5, France. a-gabelle@chu-montpellier.fr</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Portet</LastName>
<ForeName>F</ForeName>
<Initials>F</Initials>
</Author>
<Author ValidYN="Y"><LastName>Berr</LastName>
<ForeName>C</ForeName>
<Initials>C</Initials>
</Author>
<Author ValidYN="Y"><LastName>Touchon</LastName>
<ForeName>J</ForeName>
<Initials>J</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D016454">Review</PublicationType>
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</Article>
<MedlineJournalInfo><Country>France</Country>
<MedlineTA>J Nutr Health Aging</MedlineTA>
<NlmUniqueID>100893366</NlmUniqueID>
<ISSNLinking>1279-7707</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D016229">Amyloid beta-Peptides</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D004268">DNA-Binding Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D051844">alpha-Synuclein</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D016875">tau Proteins</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016229" MajorTopicYN="N">Amyloid beta-Peptides</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001921" MajorTopicYN="N">Brain</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
<QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D001923" MajorTopicYN="N">Brain Chemistry</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D004268" MajorTopicYN="N">DNA-Binding Proteins</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
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<MeshHeading><DescriptorName UI="D003704" MajorTopicYN="N">Dementia</DescriptorName>
<QualifierName UI="Q000145" MajorTopicYN="N">classification</QualifierName>
<QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003937" MajorTopicYN="N">Diagnosis, Differential</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010300" MajorTopicYN="N">Parkinson Disease</DescriptorName>
<QualifierName UI="Q000145" MajorTopicYN="N">classification</QualifierName>
<QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D051844" MajorTopicYN="N">alpha-Synuclein</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D016875" MajorTopicYN="N">tau Proteins</DescriptorName>
<QualifierName UI="Q000235" MajorTopicYN="N">genetics</QualifierName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
</MeshHeadingList>
<NumberOfReferences>77</NumberOfReferences>
</MedlineCitation>
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<Month>1</Month>
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<Hour>6</Hour>
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<name sortKey="Touchon, J" sort="Touchon, J" uniqKey="Touchon J" first="J" last="Touchon">J. Touchon</name>
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	La maladie de Parkinson en France (serveur d'exploration)
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La maladie de Parkinson en France (serveur d'exploration)

Neurodegenerative dementia and parkinsonism.

Neurodegenerative dementia and parkinsonism.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki