ParkinsonFranceV1, PubMed, Checkpoint, bibRecord, 000885

Mutations in the glucocerebrosidase gene confer a risk for Parkinson disease in North Africa.

Identifieur interne : 000885 ( PubMed/Checkpoint ); précédent : 000884; suivant : 000886

Mutations in the glucocerebrosidase gene confer a risk for Parkinson disease in North Africa.

Auteurs : S. Lesage [France] ; C. Condroyer ; N. Hecham ; M. Anheim ; S. Belarbi ; E. Lohman ; F. Viallet ; P. Pollak ; M. Abada ; A. Dürr ; M. Tazir ; A. Brice

Source :

Neurology [ 1526-632X ] ; 2011.

RBID : pubmed:21242499

English descriptors

KwdEn :
- Adolescent, Adult, Africa, Northern (ethnology), Aged, Aged, 80 and over, Female, Glucosylceramidase (genetics), Humans, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Male, Middle Aged, Mutation, Parkinson Disease (ethnology), Parkinson Disease (genetics), Protein-Serine-Threonine Kinases (genetics), Risk Factors, Young Adult.
MESH :
- chemical , genetics : Glucosylceramidase, Protein-Serine-Threonine Kinases.
- ethnology : Africa, Northern, Parkinson Disease.
- genetics : Parkinson Disease.
- Adolescent, Adult, Aged, Aged, 80 and over, Female, Humans, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Male, Middle Aged, Mutation, Risk Factors, Young Adult.

DOI: 10.1212/WNL.0b013e318207b01e
PubMed: 21242499

Affiliations:

France

Links toward previous steps (curation, corpus...)

to stream PubMed, to step Corpus: 000A08
to stream PubMed, to step Curation: 000968

Links to Exploration step

pubmed:21242499

Le document en format XML

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<author><name sortKey="Anheim, M" sort="Anheim, M" uniqKey="Anheim M" first="M" last="Anheim">M. Anheim</name>
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<author><name sortKey="Viallet, F" sort="Viallet, F" uniqKey="Viallet F" first="F" last="Viallet">F. Viallet</name>
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<author><name sortKey="Pollak, P" sort="Pollak, P" uniqKey="Pollak P" first="P" last="Pollak">P. Pollak</name>
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<author><name sortKey="Abada, M" sort="Abada, M" uniqKey="Abada M" first="M" last="Abada">M. Abada</name>
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<series><title level="j">Neurology</title>
<idno type="eISSN">1526-632X</idno>
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<term>Aged, 80 and over</term>
<term>Female</term>
<term>Glucosylceramidase (genetics)</term>
<term>Humans</term>
<term>Leucine-Rich Repeat Serine-Threonine Protein Kinase-2</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Mutation</term>
<term>Parkinson Disease (ethnology)</term>
<term>Parkinson Disease (genetics)</term>
<term>Protein-Serine-Threonine Kinases (genetics)</term>
<term>Risk Factors</term>
<term>Young Adult</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Glucosylceramidase</term>
<term>Protein-Serine-Threonine Kinases</term>
</keywords>
<keywords scheme="MESH" qualifier="ethnology" xml:lang="en"><term>Africa, Northern</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adolescent</term>
<term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Female</term>
<term>Humans</term>
<term>Leucine-Rich Repeat Serine-Threonine Protein Kinase-2</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Mutation</term>
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<DateCreated><Year>2011</Year>
<Month>01</Month>
<Day>18</Day>
</DateCreated>
<DateCompleted><Year>2011</Year>
<Month>02</Month>
<Day>14</Day>
</DateCompleted>
<DateRevised><Year>2016</Year>
<Month>11</Month>
<Day>25</Day>
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<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1526-632X</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>76</Volume>
<Issue>3</Issue>
<PubDate><Year>2011</Year>
<Month>Jan</Month>
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</JournalIssue>
<Title>Neurology</Title>
<ISOAbbreviation>Neurology</ISOAbbreviation>
</Journal>
<ArticleTitle>Mutations in the glucocerebrosidase gene confer a risk for Parkinson disease in North Africa.</ArticleTitle>
<Pagination><MedlinePgn>301-3</MedlinePgn>
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<ELocationID EIdType="doi" ValidYN="Y">10.1212/WNL.0b013e318207b01e</ELocationID>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Lesage</LastName>
<ForeName>S</ForeName>
<Initials>S</Initials>
<AffiliationInfo><Affiliation>INSERM UMR_S975 (formerly UMR_S679), Hôpital de la Salpêtrière, Paris cedex 13, France. alexis.brice@upmc.fr</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Condroyer</LastName>
<ForeName>C</ForeName>
<Initials>C</Initials>
</Author>
<Author ValidYN="Y"><LastName>Hecham</LastName>
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</Author>
<Author ValidYN="Y"><LastName>Anheim</LastName>
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</Author>
<Author ValidYN="Y"><LastName>Belarbi</LastName>
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</Author>
<Author ValidYN="Y"><LastName>Lohman</LastName>
<ForeName>E</ForeName>
<Initials>E</Initials>
</Author>
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</Author>
<Author ValidYN="Y"><CollectiveName>French Parkinson Disease Genetic Group</CollectiveName>
</Author>
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</PublicationTypeList>
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<MedlineJournalInfo><Country>United States</Country>
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<NlmUniqueID>0401060</NlmUniqueID>
<ISSNLinking>0028-3878</ISSNLinking>
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<ChemicalList><Chemical><RegistryNumber>EC 2.7.11.1</RegistryNumber>
<NameOfSubstance UI="C495280">LRRK2 protein, human</NameOfSubstance>
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<Chemical><RegistryNumber>EC 2.7.11.1</RegistryNumber>
<NameOfSubstance UI="D000071158">Leucine-Rich Repeat Serine-Threonine Protein Kinase-2</NameOfSubstance>
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<CitationSubset>AIM</CitationSubset>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D000293" MajorTopicYN="N">Adolescent</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
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<MeshHeading><DescriptorName UI="D000071158" MajorTopicYN="N">Leucine-Rich Repeat Serine-Threonine Protein Kinase-2</DescriptorName>
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<MeshHeading><DescriptorName UI="D012307" MajorTopicYN="N">Risk Factors</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D055815" MajorTopicYN="N">Young Adult</DescriptorName>
</MeshHeading>
</MeshHeadingList>
<InvestigatorList><Investigator ValidYN="Y"><LastName>Agid</LastName>
<ForeName>Yves</ForeName>
<Initials>Y</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Anheim</LastName>
<ForeName>Mathieu</ForeName>
<Initials>M</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Bonnet</LastName>
<ForeName>A-M</ForeName>
<Initials>AM</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Borg</LastName>
<ForeName>Michel</ForeName>
<Initials>M</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Brice</LastName>
<ForeName>Alexis</ForeName>
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<ForeName>Emmanuel</ForeName>
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<Investigator ValidYN="Y"><LastName>Corvol</LastName>
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<Investigator ValidYN="Y"><LastName>Destée</LastName>
<ForeName>Alain</ForeName>
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<Investigator ValidYN="Y"><LastName>Dürr</LastName>
<ForeName>Alexandra</ForeName>
<Initials>A</Initials>
</Investigator>
<Investigator ValidYN="Y"><LastName>Durif</LastName>
<ForeName>Franck</ForeName>
<Initials>F</Initials>
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<Investigator ValidYN="Y"><LastName>Lesage</LastName>
<ForeName>Suzanne</ForeName>
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<Investigator ValidYN="Y"><LastName>Lohmann</LastName>
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<Investigator ValidYN="Y"><LastName>Martinez</LastName>
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<Investigator ValidYN="Y"><LastName>Penet</LastName>
<ForeName>Christiane</ForeName>
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<Investigator ValidYN="Y"><LastName>Tison</LastName>
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<Investigator ValidYN="Y"><LastName>Tranchant</LastName>
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<Initials>C</Initials>
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<Investigator ValidYN="Y"><LastName>Vérin</LastName>
<ForeName>Marc</ForeName>
<Initials>M</Initials>
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<Investigator ValidYN="Y"><LastName>Viallet</LastName>
<ForeName>François</ForeName>
<Initials>F</Initials>
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<Investigator ValidYN="Y"><LastName>Vidailhet</LastName>
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<name sortKey="Anheim, M" sort="Anheim, M" uniqKey="Anheim M" first="M" last="Anheim">M. Anheim</name>
<name sortKey="Belarbi, S" sort="Belarbi, S" uniqKey="Belarbi S" first="S" last="Belarbi">S. Belarbi</name>
<name sortKey="Brice, A" sort="Brice, A" uniqKey="Brice A" first="A" last="Brice">A. Brice</name>
<name sortKey="Condroyer, C" sort="Condroyer, C" uniqKey="Condroyer C" first="C" last="Condroyer">C. Condroyer</name>
<name sortKey="Durr, A" sort="Durr, A" uniqKey="Durr A" first="A" last="Dürr">A. Dürr</name>
<name sortKey="Hecham, N" sort="Hecham, N" uniqKey="Hecham N" first="N" last="Hecham">N. Hecham</name>
<name sortKey="Lohman, E" sort="Lohman, E" uniqKey="Lohman E" first="E" last="Lohman">E. Lohman</name>
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<country name="France"><noRegion><name sortKey="Lesage, S" sort="Lesage, S" uniqKey="Lesage S" first="S" last="Lesage">S. Lesage</name>
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	La maladie de Parkinson en France (serveur d'exploration)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

La maladie de Parkinson en France (serveur d'exploration)

Mutations in the glucocerebrosidase gene confer a risk for Parkinson disease in North Africa.

Mutations in the glucocerebrosidase gene confer a risk for Parkinson disease in North Africa.

Source :

English descriptors

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