Links to Exploration step
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">From epidemiology to pathophysiology: what about caffeine in Alzheimer’s disease?</title><author><name sortKey="Flaten, Vanessa" sort="Flaten, Vanessa" uniqKey="Flaten V" first="Vanessa" last="Flaten">Vanessa Flaten</name><affiliation><nlm:aff id="A1">Inserm U837, F-59045 Lille France</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Université Lille-Nord de France, UDSL, Jean-Pierre Aubert Research Centre, Institut de Médecine Prédictive et de Recherche Thérapeutique, F-59045 Lille, France</nlm:aff></affiliation></author><author><name sortKey="Laurent, Cyril" sort="Laurent, Cyril" uniqKey="Laurent C" first="Cyril" last="Laurent">Cyril Laurent</name><affiliation><nlm:aff id="A1">Inserm U837, F-59045 Lille France</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Université Lille-Nord de France, UDSL, Jean-Pierre Aubert Research Centre, Institut de Médecine Prédictive et de Recherche Thérapeutique, F-59045 Lille, France</nlm:aff></affiliation></author><author><name sortKey="Coelho, Joana E" sort="Coelho, Joana E" uniqKey="Coelho J" first="Joana E." last="Coelho">Joana E. Coelho</name><affiliation><nlm:aff id="A3">Instituto de Medicina Molecular, Lisbon, Portugal</nlm:aff></affiliation></author><author><name sortKey="Sandau, Ursula" sort="Sandau, Ursula" uniqKey="Sandau U" first="Ursula" last="Sandau">Ursula Sandau</name><affiliation><nlm:aff id="A4">Legacy Research Institute, Portland, OR 97232, USA</nlm:aff></affiliation></author><author><name sortKey="Batalha, Vania L" sort="Batalha, Vania L" uniqKey="Batalha V" first="Vânia L." last="Batalha">Vânia L. Batalha</name><affiliation><nlm:aff id="A3">Instituto de Medicina Molecular, Lisbon, Portugal</nlm:aff></affiliation></author><author><name sortKey="Burnouf, Sylvie" sort="Burnouf, Sylvie" uniqKey="Burnouf S" first="Sylvie" last="Burnouf">Sylvie Burnouf</name><affiliation><nlm:aff id="A1">Inserm U837, F-59045 Lille France</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Université Lille-Nord de France, UDSL, Jean-Pierre Aubert Research Centre, Institut de Médecine Prédictive et de Recherche Thérapeutique, F-59045 Lille, France</nlm:aff></affiliation><affiliation><nlm:aff id="A5">Max Planck Institute for Biology of Ageing, Köln, Germany</nlm:aff></affiliation></author><author><name sortKey="Hamdane, Malika" sort="Hamdane, Malika" uniqKey="Hamdane M" first="Malika" last="Hamdane">Malika Hamdane</name><affiliation><nlm:aff id="A1">Inserm U837, F-59045 Lille France</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Université Lille-Nord de France, UDSL, Jean-Pierre Aubert Research Centre, Institut de Médecine Prédictive et de Recherche Thérapeutique, F-59045 Lille, France</nlm:aff></affiliation><affiliation><nlm:aff id="A3">Instituto de Medicina Molecular, Lisbon, Portugal</nlm:aff></affiliation></author><author><name sortKey="Humez, Sandrine" sort="Humez, Sandrine" uniqKey="Humez S" first="Sandrine" last="Humez">Sandrine Humez</name><affiliation><nlm:aff id="A1">Inserm U837, F-59045 Lille France</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Université Lille-Nord de France, UDSL, Jean-Pierre Aubert Research Centre, Institut de Médecine Prédictive et de Recherche Thérapeutique, F-59045 Lille, France</nlm:aff></affiliation></author><author><name sortKey="Boison, Detlev" sort="Boison, Detlev" uniqKey="Boison D" first="Detlev" last="Boison">Detlev Boison</name><affiliation><nlm:aff id="A4">Legacy Research Institute, Portland, OR 97232, USA</nlm:aff></affiliation></author><author><name sortKey="Lopes, Luisa V" sort="Lopes, Luisa V" uniqKey="Lopes L" first="Luísa V." last="Lopes">Luísa V. Lopes</name><affiliation><nlm:aff id="A3">Instituto de Medicina Molecular, Lisbon, Portugal</nlm:aff></affiliation></author><author><name sortKey="Buee, Luc" sort="Buee, Luc" uniqKey="Buee L" first="Luc" last="Buée">Luc Buée</name><affiliation><nlm:aff id="A1">Inserm U837, F-59045 Lille France</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Université Lille-Nord de France, UDSL, Jean-Pierre Aubert Research Centre, Institut de Médecine Prédictive et de Recherche Thérapeutique, F-59045 Lille, France</nlm:aff></affiliation><affiliation><nlm:aff id="A6">CHRU, F-59037 Lille, France</nlm:aff></affiliation></author><author><name sortKey="Blum, David" sort="Blum, David" uniqKey="Blum D" first="David" last="Blum">David Blum</name><affiliation><nlm:aff id="A1">Inserm U837, F-59045 Lille France</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Université Lille-Nord de France, UDSL, Jean-Pierre Aubert Research Centre, Institut de Médecine Prédictive et de Recherche Thérapeutique, F-59045 Lille, France</nlm:aff></affiliation><affiliation><nlm:aff id="A6">CHRU, F-59037 Lille, France</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24646282</idno><idno type="pmc">4440674</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4440674</idno><idno type="RBID">PMC:4440674</idno><idno type="doi">10.1042/BST20130229</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">000620</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000620</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">From epidemiology to pathophysiology: what about caffeine in Alzheimer’s disease?</title><author><name sortKey="Flaten, Vanessa" sort="Flaten, Vanessa" uniqKey="Flaten V" first="Vanessa" last="Flaten">Vanessa Flaten</name><affiliation><nlm:aff id="A1">Inserm U837, F-59045 Lille France</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Université Lille-Nord de France, UDSL, Jean-Pierre Aubert Research Centre, Institut de Médecine Prédictive et de Recherche Thérapeutique, F-59045 Lille, France</nlm:aff></affiliation></author><author><name sortKey="Laurent, Cyril" sort="Laurent, Cyril" uniqKey="Laurent C" first="Cyril" last="Laurent">Cyril Laurent</name><affiliation><nlm:aff id="A1">Inserm U837, F-59045 Lille France</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Université Lille-Nord de France, UDSL, Jean-Pierre Aubert Research Centre, Institut de Médecine Prédictive et de Recherche Thérapeutique, F-59045 Lille, France</nlm:aff></affiliation></author><author><name sortKey="Coelho, Joana E" sort="Coelho, Joana E" uniqKey="Coelho J" first="Joana E." last="Coelho">Joana E. Coelho</name><affiliation><nlm:aff id="A3">Instituto de Medicina Molecular, Lisbon, Portugal</nlm:aff></affiliation></author><author><name sortKey="Sandau, Ursula" sort="Sandau, Ursula" uniqKey="Sandau U" first="Ursula" last="Sandau">Ursula Sandau</name><affiliation><nlm:aff id="A4">Legacy Research Institute, Portland, OR 97232, USA</nlm:aff></affiliation></author><author><name sortKey="Batalha, Vania L" sort="Batalha, Vania L" uniqKey="Batalha V" first="Vânia L." last="Batalha">Vânia L. Batalha</name><affiliation><nlm:aff id="A3">Instituto de Medicina Molecular, Lisbon, Portugal</nlm:aff></affiliation></author><author><name sortKey="Burnouf, Sylvie" sort="Burnouf, Sylvie" uniqKey="Burnouf S" first="Sylvie" last="Burnouf">Sylvie Burnouf</name><affiliation><nlm:aff id="A1">Inserm U837, F-59045 Lille France</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Université Lille-Nord de France, UDSL, Jean-Pierre Aubert Research Centre, Institut de Médecine Prédictive et de Recherche Thérapeutique, F-59045 Lille, France</nlm:aff></affiliation><affiliation><nlm:aff id="A5">Max Planck Institute for Biology of Ageing, Köln, Germany</nlm:aff></affiliation></author><author><name sortKey="Hamdane, Malika" sort="Hamdane, Malika" uniqKey="Hamdane M" first="Malika" last="Hamdane">Malika Hamdane</name><affiliation><nlm:aff id="A1">Inserm U837, F-59045 Lille France</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Université Lille-Nord de France, UDSL, Jean-Pierre Aubert Research Centre, Institut de Médecine Prédictive et de Recherche Thérapeutique, F-59045 Lille, France</nlm:aff></affiliation><affiliation><nlm:aff id="A3">Instituto de Medicina Molecular, Lisbon, Portugal</nlm:aff></affiliation></author><author><name sortKey="Humez, Sandrine" sort="Humez, Sandrine" uniqKey="Humez S" first="Sandrine" last="Humez">Sandrine Humez</name><affiliation><nlm:aff id="A1">Inserm U837, F-59045 Lille France</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Université Lille-Nord de France, UDSL, Jean-Pierre Aubert Research Centre, Institut de Médecine Prédictive et de Recherche Thérapeutique, F-59045 Lille, France</nlm:aff></affiliation></author><author><name sortKey="Boison, Detlev" sort="Boison, Detlev" uniqKey="Boison D" first="Detlev" last="Boison">Detlev Boison</name><affiliation><nlm:aff id="A4">Legacy Research Institute, Portland, OR 97232, USA</nlm:aff></affiliation></author><author><name sortKey="Lopes, Luisa V" sort="Lopes, Luisa V" uniqKey="Lopes L" first="Luísa V." last="Lopes">Luísa V. Lopes</name><affiliation><nlm:aff id="A3">Instituto de Medicina Molecular, Lisbon, Portugal</nlm:aff></affiliation></author><author><name sortKey="Buee, Luc" sort="Buee, Luc" uniqKey="Buee L" first="Luc" last="Buée">Luc Buée</name><affiliation><nlm:aff id="A1">Inserm U837, F-59045 Lille France</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Université Lille-Nord de France, UDSL, Jean-Pierre Aubert Research Centre, Institut de Médecine Prédictive et de Recherche Thérapeutique, F-59045 Lille, France</nlm:aff></affiliation><affiliation><nlm:aff id="A6">CHRU, F-59037 Lille, France</nlm:aff></affiliation></author><author><name sortKey="Blum, David" sort="Blum, David" uniqKey="Blum D" first="David" last="Blum">David Blum</name><affiliation><nlm:aff id="A1">Inserm U837, F-59045 Lille France</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Université Lille-Nord de France, UDSL, Jean-Pierre Aubert Research Centre, Institut de Médecine Prédictive et de Recherche Thérapeutique, F-59045 Lille, France</nlm:aff></affiliation><affiliation><nlm:aff id="A6">CHRU, F-59037 Lille, France</nlm:aff></affiliation></author></analytic><series><title level="j">Biochemical Society transactions</title><idno type="ISSN">0300-5127</idno><idno type="eISSN">1470-8752</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">Alzheimer’s disease (AD) is the most prevalent form of dementia in the aged population. Definitive diagnosis of AD is based on the presence of senile plaques and neurofibrillary tangles that are identified in post-mortem brain specimens. A third pathological component is inflammation. AD results from multiple genetic and environmental risk factors. Among other factors, epidemiological studies report beneficial effects of caffeine, a non-selective antagonist of adenosine receptors. In the present review, we discuss the impact of caffeine and the adenosinergic system in AD pathology as well as consequences in terms of pathology and therapeutics.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">7506897</journal-id><journal-id journal-id-type="pubmed-jr-id">3328</journal-id><journal-id journal-id-type="nlm-ta">Biochem Soc Trans</journal-id><journal-id journal-id-type="iso-abbrev">Biochem. Soc. Trans.</journal-id><journal-title-group><journal-title>Biochemical Society transactions</journal-title></journal-title-group><issn pub-type="ppub">0300-5127</issn><issn pub-type="epub">1470-8752</issn></journal-meta><article-meta><article-id pub-id-type="pmid">24646282</article-id><article-id pub-id-type="pmc">4440674</article-id><article-id pub-id-type="doi">10.1042/BST20130229</article-id><article-id pub-id-type="manuscript">NIHMS690166</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>From epidemiology to pathophysiology: what about caffeine in Alzheimer’s disease?</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Flaten</surname><given-names>Vanessa</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Laurent</surname><given-names>Cyril</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Coelho</surname><given-names>Joana E.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Sandau</surname><given-names>Ursula</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Batalha</surname><given-names>Vânia L.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Burnouf</surname><given-names>Sylvie</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A2">2</xref><xref ref-type="aff" rid="A5">5</xref></contrib><contrib contrib-type="author"><name><surname>Hamdane</surname><given-names>Malika</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A2">2</xref><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Humez</surname><given-names>Sandrine</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A2">2</xref></contrib><contrib contrib-type="author"><name><surname>Boison</surname><given-names>Detlev</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Lopes</surname><given-names>Luísa V.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Buée</surname><given-names>Luc</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A2">2</xref><xref ref-type="aff" rid="A6">6</xref></contrib><contrib contrib-type="author"><name><surname>Blum</surname><given-names>David</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A2">2</xref><xref ref-type="aff" rid="A6">6</xref></contrib></contrib-group><aff id="A1"><label>1</label>Inserm U837, F-59045 Lille France</aff><aff id="A2"><label>2</label>Université Lille-Nord de France, UDSL, Jean-Pierre Aubert Research Centre, Institut de Médecine Prédictive et de Recherche Thérapeutique, F-59045 Lille, France</aff><aff id="A3"><label>3</label>Instituto de Medicina Molecular, Lisbon, Portugal</aff><aff id="A4"><label>4</label>Legacy Research Institute, Portland, OR 97232, USA</aff><aff id="A5"><label>5</label>Max Planck Institute for Biology of Ageing, Köln, Germany</aff><aff id="A6"><label>6</label>CHRU, F-59037 Lille, France</aff><author-notes><corresp id="FN1">Corresponding author: David Blum, Inserm U837, 1 place de Verdun, 59045 Lille Cedex, France. Tel: +33320298858; <email>david.blum@inserm.fr</email></corresp></author-notes><pub-date pub-type="nihms-submitted"><day>14</day><month>5</month><year>2015</year></pub-date><pub-date pub-type="ppub"><month>4</month><year>2014</year></pub-date><pub-date pub-type="pmc-release"><day>21</day><month>5</month><year>2015</year></pub-date><volume>42</volume><issue>2</issue><fpage>587</fpage><lpage>592</lpage><pmc-comment>elocation-id from pubmed: 10.1042/BST20130229</pmc-comment>
<abstract><p id="P1">Alzheimer’s disease (AD) is the most prevalent form of dementia in the aged population. Definitive diagnosis of AD is based on the presence of senile plaques and neurofibrillary tangles that are identified in post-mortem brain specimens. A third pathological component is inflammation. AD results from multiple genetic and environmental risk factors. Among other factors, epidemiological studies report beneficial effects of caffeine, a non-selective antagonist of adenosine receptors. In the present review, we discuss the impact of caffeine and the adenosinergic system in AD pathology as well as consequences in terms of pathology and therapeutics.</p></abstract><kwd-group><kwd>Alzheimer’s disease</kwd><kwd>caffeine</kwd><kwd>adenosine receptors</kwd><kwd>adenosine</kwd><kwd>epidemiology</kwd><kwd>A2A</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000620 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 000620 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonFranceV1
|flux= Pmc
|étape= Corpus
|type= RBID
|clé=
|texte=
}}
| This area was generated with Dilib version V0.6.29. |  |