Links to Exploration step
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Proteomics in Immunity and Herpes Simplex Encephalitis</title><author><name sortKey="De Diego, Rebeca Perez" sort="De Diego, Rebeca Perez" uniqKey="De Diego R" first="Rebeca Pérez" last="De Diego">Rebeca Pérez De Diego</name><affiliation><nlm:aff id="A1">Immunology Unit, IdiPAZ Institute for Health Research, La Paz University Hospital, 261 P° Castellana, Madrid 28046, Spain, EU</nlm:aff></affiliation></author><author><name sortKey="Mulvey, Claire" sort="Mulvey, Claire" uniqKey="Mulvey C" first="Claire" last="Mulvey">Claire Mulvey</name><affiliation><nlm:aff id="A2">Division of Medicine, University College London, Centre for Nephrology, Royal Free Campus, Rowland Hill Street, London NW3 2PF, UK, EU</nlm:aff></affiliation></author><author><name sortKey="Casanova, Jean Laurent" sort="Casanova, Jean Laurent" uniqKey="Casanova J" first="Jean-Laurent" last="Casanova">Jean-Laurent Casanova</name><affiliation><nlm:aff id="A3">Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U980, Necker Medical School, Paris 75015, France, EU</nlm:aff></affiliation><affiliation><nlm:aff id="A4">University Paris Descartes, Paris 75015, France, EU</nlm:aff></affiliation><affiliation><nlm:aff id="A5">St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY 10065, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Prince NaifCenter for Immunology Research, Department of Pediatrics, College of Medicine, King Saud University, Riyadh 11451, Saudi Arabia</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Pediatric Hematology-Immunology Unit, Necker Hospital, Paris 75015, France, EU</nlm:aff></affiliation></author><author><name sortKey="Godovac Zimmermann, Jasminka" sort="Godovac Zimmermann, Jasminka" uniqKey="Godovac Zimmermann J" first="Jasminka" last="Godovac-Zimmermann">Jasminka Godovac-Zimmermann</name><affiliation><nlm:aff id="A2">Division of Medicine, University College London, Centre for Nephrology, Royal Free Campus, Rowland Hill Street, London NW3 2PF, UK, EU</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">24351021</idno><idno type="pmc">4070007</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4070007</idno><idno type="RBID">PMC:4070007</idno><idno type="doi">10.1586/14789450.2014.864954</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">000598</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000598</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Proteomics in Immunity and Herpes Simplex Encephalitis</title><author><name sortKey="De Diego, Rebeca Perez" sort="De Diego, Rebeca Perez" uniqKey="De Diego R" first="Rebeca Pérez" last="De Diego">Rebeca Pérez De Diego</name><affiliation><nlm:aff id="A1">Immunology Unit, IdiPAZ Institute for Health Research, La Paz University Hospital, 261 P° Castellana, Madrid 28046, Spain, EU</nlm:aff></affiliation></author><author><name sortKey="Mulvey, Claire" sort="Mulvey, Claire" uniqKey="Mulvey C" first="Claire" last="Mulvey">Claire Mulvey</name><affiliation><nlm:aff id="A2">Division of Medicine, University College London, Centre for Nephrology, Royal Free Campus, Rowland Hill Street, London NW3 2PF, UK, EU</nlm:aff></affiliation></author><author><name sortKey="Casanova, Jean Laurent" sort="Casanova, Jean Laurent" uniqKey="Casanova J" first="Jean-Laurent" last="Casanova">Jean-Laurent Casanova</name><affiliation><nlm:aff id="A3">Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U980, Necker Medical School, Paris 75015, France, EU</nlm:aff></affiliation><affiliation><nlm:aff id="A4">University Paris Descartes, Paris 75015, France, EU</nlm:aff></affiliation><affiliation><nlm:aff id="A5">St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY 10065, USA</nlm:aff></affiliation><affiliation><nlm:aff id="A6">Prince NaifCenter for Immunology Research, Department of Pediatrics, College of Medicine, King Saud University, Riyadh 11451, Saudi Arabia</nlm:aff></affiliation><affiliation><nlm:aff id="A7">Pediatric Hematology-Immunology Unit, Necker Hospital, Paris 75015, France, EU</nlm:aff></affiliation></author><author><name sortKey="Godovac Zimmermann, Jasminka" sort="Godovac Zimmermann, Jasminka" uniqKey="Godovac Zimmermann J" first="Jasminka" last="Godovac-Zimmermann">Jasminka Godovac-Zimmermann</name><affiliation><nlm:aff id="A2">Division of Medicine, University College London, Centre for Nephrology, Royal Free Campus, Rowland Hill Street, London NW3 2PF, UK, EU</nlm:aff></affiliation></author></analytic><series><title level="j">Expert review of proteomics</title><idno type="ISSN">1478-9450</idno><idno type="eISSN">1744-8387</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P1">The genetic theory of infectious diseases has proposed that susceptibility to life-threatening infectious diseases in childhood, occurring in the course of primary infection, results mostly from individually rare but collectively diverse single-gene variants. Recent evidence for an ever-expanding spectrum of genes involved in susceptibility to infectious disease indicates the paradigm has important implications for diagnosis and treatment. One such pathology is childhood herpes simplex encephalitis (HSE), which shows a pattern of rare, but diverse disease-disposing genetic variants. The present report shows how proteomics can help to understand susceptibility to childhood HSE and other viral infections, suggests proteomics may have a particularly important role to play, emphasizes that variation over the population is a critical issue for proteomics and notes some new challenges for proteomics and related bioinformatics tools in the context of rare, but diverse genetic defects.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">101223548</journal-id><journal-id journal-id-type="pubmed-jr-id">32340</journal-id><journal-id journal-id-type="nlm-ta">Expert Rev Proteomics</journal-id><journal-id journal-id-type="iso-abbrev">Expert Rev Proteomics</journal-id><journal-title-group><journal-title>Expert review of proteomics</journal-title></journal-title-group><issn pub-type="ppub">1478-9450</issn><issn pub-type="epub">1744-8387</issn></journal-meta><article-meta><article-id pub-id-type="pmid">24351021</article-id><article-id pub-id-type="pmc">4070007</article-id><article-id pub-id-type="doi">10.1586/14789450.2014.864954</article-id><article-id pub-id-type="manuscript">NIHMS587766</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Proteomics in Immunity and Herpes Simplex Encephalitis</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>de Diego</surname><given-names>Rebeca Pérez</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Mulvey</surname><given-names>Claire</given-names></name><xref ref-type="aff" rid="A2">2</xref><xref rid="FN2" ref-type="author-notes">‡</xref></contrib><contrib contrib-type="author"><name><surname>Casanova</surname><given-names>Jean-Laurent</given-names></name><xref ref-type="aff" rid="A3">3</xref><xref ref-type="aff" rid="A4">4</xref><xref ref-type="aff" rid="A5">5</xref><xref ref-type="aff" rid="A6">6</xref><xref ref-type="aff" rid="A7">7</xref></contrib><contrib contrib-type="author"><name><surname>Godovac-Zimmermann</surname><given-names>Jasminka</given-names></name><xref ref-type="aff" rid="A2">2</xref><xref rid="FN1" ref-type="author-notes">*</xref></contrib></contrib-group><aff id="A1"><label>1</label>Immunology Unit, IdiPAZ Institute for Health Research, La Paz University Hospital, 261 P° Castellana, Madrid 28046, Spain, EU</aff><aff id="A2"><label>2</label>Division of Medicine, University College London, Centre for Nephrology, Royal Free Campus, Rowland Hill Street, London NW3 2PF, UK, EU</aff><aff id="A3"><label>3</label>Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U980, Necker Medical School, Paris 75015, France, EU</aff><aff id="A4"><label>4</label>University Paris Descartes, Paris 75015, France, EU</aff><aff id="A5"><label>5</label>St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY 10065, USA</aff><aff id="A6"><label>6</label>Prince NaifCenter for Immunology Research, Department of Pediatrics, College of Medicine, King Saud University, Riyadh 11451, Saudi Arabia</aff><aff id="A7"><label>7</label>Pediatric Hematology-Immunology Unit, Necker Hospital, Paris 75015, France, EU</aff><author-notes><corresp id="FN1"><label>*</label>Corresponding author: Jasminka Godovac-Zimmermann <email>j.godovac-zimmermann@ucl.ac.uk</email></corresp><fn id="FN2" fn-type="present-address"><label>‡</label><p>Present Address: Cambridge Centre for Proteomics, Cambridge Systems Biology Centre, Department of Biochemistry, University of Cambridge, Tennis Court Road, CB2 1QR, Cambridge, UK, EU.</p></fn></author-notes><pub-date pub-type="nihms-submitted"><day>22</day><month>5</month><year>2014</year></pub-date><pub-date pub-type="epub"><day>18</day><month>12</month><year>2013</year></pub-date><pub-date pub-type="ppub"><month>2</month><year>2014</year></pub-date><pub-date pub-type="pmc-release"><day>01</day><month>2</month><year>2015</year></pub-date><volume>11</volume><issue>1</issue><fpage>21</fpage><lpage>29</lpage><pmc-comment>elocation-id from pubmed: 10.1586/14789450.2014.864954</pmc-comment>
<abstract><p id="P1">The genetic theory of infectious diseases has proposed that susceptibility to life-threatening infectious diseases in childhood, occurring in the course of primary infection, results mostly from individually rare but collectively diverse single-gene variants. Recent evidence for an ever-expanding spectrum of genes involved in susceptibility to infectious disease indicates the paradigm has important implications for diagnosis and treatment. One such pathology is childhood herpes simplex encephalitis (HSE), which shows a pattern of rare, but diverse disease-disposing genetic variants. The present report shows how proteomics can help to understand susceptibility to childhood HSE and other viral infections, suggests proteomics may have a particularly important role to play, emphasizes that variation over the population is a critical issue for proteomics and notes some new challenges for proteomics and related bioinformatics tools in the context of rare, but diverse genetic defects.</p></abstract><kwd-group><kwd>Infectious diseases</kwd><kwd>Herpes simplex encephalitis (HSE)</kwd><kwd>SILAC</kwd><kwd>herpes simplex virus 1 (HSV-1)</kwd><kwd>TLR3</kwd><kwd>interferon (IFN)</kwd><kwd>proteomics</kwd><kwd>genomics</kwd><kwd>systems biology</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 0005980 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 0005980 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonFranceV1
|flux= Pmc
|étape= Corpus
|type= RBID
|clé=
|texte=
}}
| This area was generated with Dilib version V0.6.29. |  |