Microtubules: 50 years on from the discovery of tubulin
Identifieur interne : 000590 ( Pmc/Corpus ); précédent : 000589; suivant : 000591Microtubules: 50 years on from the discovery of tubulin
Auteurs : Gary BorisySource :
- Nature reviews. Molecular cell biology [ 1471-0072 ] ; 2016.
Abstract
Next year will be the 50th anniversary of the discovery of tubulin. To celebrate this discovery, six leaders in the field of microtubule research reflect on key findings and technological breakthroughs over the past five decades, discuss implications for therapeutic applications and provide their thoughts on what questions need to be addressed in the near future.
Url:
DOI: 10.1038/nrm.2016.45
PubMed: 27103327
PubMed Central: 5116387
Links to Exploration step
PMC:5116387Le document en format XML
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<front><div type="abstract" xml:lang="en"><p id="P1">Next year will be the 50th anniversary of the discovery of tubulin. To celebrate this discovery, six leaders in the field of microtubule research reflect on key findings and technological breakthroughs over the past five decades, discuss implications for therapeutic applications and provide their thoughts on what questions need to be addressed in the near future.</p>
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<title-group><article-title>Microtubules: 50 years on from the discovery of tubulin</article-title>
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<contrib-group><contrib contrib-type="author"><name><surname>Borisy</surname>
<given-names>Gary</given-names>
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<aff id="A1">Forsyth Institute, 245 First Street, Cambridge, Massachusetts 02142, USA.<email>gborisy@forsyth.org</email>
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<contrib-group><contrib contrib-type="author"><name><surname>Heald</surname>
<given-names>Rebecca</given-names>
</name>
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<aff id="A2">Division of Cell and Developmental Biology and Molecular and Cell Biology Department, University of California, Berkeley, California 94720, USA.<email>bheald@berkeley.edu</email>
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<contrib-group><contrib contrib-type="author"><name><surname>Howard</surname>
<given-names>Jonathon</given-names>
</name>
</contrib>
<aff id="A3">Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06510, USA.<email>jonathon.howard@yale.edu</email>
</aff>
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<contrib-group><contrib contrib-type="author"><name><surname>Janke</surname>
<given-names>Carsten</given-names>
</name>
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<aff id="A4">Institut Curie, PSL Research University, CNRS UMR3348, Centre Universitaire, Bâtiment 110, F-91405 Orsay, France.<email>carsten.janke@curie.fr</email>
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<contrib-group><contrib contrib-type="author"><name><surname>Musacchio</surname>
<given-names>Andrea</given-names>
</name>
</contrib>
<aff id="A5">Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany; and the Centre for Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Universitätsstrasse, 45141 Essen, Germany.<email>andrea.musacchio@mpi-dortmund.mpg.de</email>
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<contrib-group><contrib contrib-type="author"><name><surname>Nogales</surname>
<given-names>Eva</given-names>
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<aff id="A6">Biochemistry, Biophysics and Structural Biology Division, Molecular and Cell Biology Department, University of California, Berkeley, California 94720-3220, USA; the Howard Hughes Medical Institute, Maryland, USA; and the Lawrence Berkeley National Laboratory, USA.<email>enogales@lbl.gov</email>
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<pmc-comment>elocation-id from pubmed: 10.1038/nrm.2016.45</pmc-comment>
<abstract><p id="P1">Next year will be the 50th anniversary of the discovery of tubulin. To celebrate this discovery, six leaders in the field of microtubule research reflect on key findings and technological breakthroughs over the past five decades, discuss implications for therapeutic applications and provide their thoughts on what questions need to be addressed in the near future.</p>
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