Synchronisation in the beta frequency-band — The bad boy of parkinsonism or an innocent bystander?
Identifieur interne : 000792 ( Pmc/Checkpoint ); précédent : 000791; suivant : 000793Synchronisation in the beta frequency-band — The bad boy of parkinsonism or an innocent bystander?
Auteurs : Alexandre Eusebio [France, Royaume-Uni] ; Peter Brown [Royaume-Uni]Source :
- Experimental Neurology [ 0014-4886 ] ; 2009.
Abstract
Excessive synchronisation of basal ganglia neuronal activity in the beta frequency band has been implicated in Parkinson's disease. In a recent issue of Experimental Neurology, Bronte-Stewart, H., Barberini, C., Koop, M.M., Hill, B.C., Henderson, J.M., Wingeier, B., 2009. The STN beta-band profile in Parkinson's disease is stationary and shows prolonged attenuation after deep brain stimulation. Exp. Neurol. 215, 20–28. demonstrate that such activity is consistent over time and provide further evidence that deep brain stimulation is associated with its suppression. However, the extent to which beta synchrony has a mechanistic (rather than epiphenomenal) role in parkinsonism remains unclear, and the suppression of this activity by deep brain stimulation is contentious. This commentary discusses the evidence for and against a role for excessive beta synchrony in mediating the parkinsonian phenotype and in providing a possible mechanism to explain the therapeutic effects of deep brain stimulation in Parkinson's disease.
Url:
DOI: 10.1016/j.expneurol.2009.02.003
PubMed: 19233172
PubMed Central: 2697315
Affiliations:
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<front><div type="abstract" xml:lang="en"><p>Excessive synchronisation of basal ganglia neuronal activity in the beta frequency band has been implicated in Parkinson's disease. In a recent issue of Experimental Neurology, Bronte-Stewart, H., Barberini, C., Koop, M.M., Hill, B.C., Henderson, J.M., Wingeier, B., 2009. The STN beta-band profile in Parkinson's disease is stationary and shows prolonged attenuation after deep brain stimulation. Exp. Neurol. 215, 20–28. demonstrate that such activity is consistent over time and provide further evidence that deep brain stimulation is associated with its suppression. However, the extent to which beta synchrony has a mechanistic (rather than epiphenomenal) role in parkinsonism remains unclear, and the suppression of this activity by deep brain stimulation is contentious. This commentary discusses the evidence for and against a role for excessive beta synchrony in mediating the parkinsonian phenotype and in providing a possible mechanism to explain the therapeutic effects of deep brain stimulation in Parkinson's disease.</p>
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<back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Amirnovin, R" uniqKey="Amirnovin R">R. Amirnovin</name>
</author>
<author><name sortKey="Williams, Z M" uniqKey="Williams Z">Z.M. Williams</name>
</author>
<author><name sortKey="Cosgrove, G R" uniqKey="Cosgrove G">G.R. Cosgrove</name>
</author>
<author><name sortKey="Eskandar, E N" uniqKey="Eskandar E">E.N. Eskandar</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Bronte Stewart, H" uniqKey="Bronte Stewart H">H. Bronte-Stewart</name>
</author>
<author><name sortKey="Barberini, C" uniqKey="Barberini C">C. Barberini</name>
</author>
<author><name sortKey="Koop, M M" uniqKey="Koop M">M.M. Koop</name>
</author>
<author><name sortKey="Hill, B C" uniqKey="Hill B">B.C. Hill</name>
</author>
<author><name sortKey="Henderson, J M" uniqKey="Henderson J">J.M. Henderson</name>
</author>
<author><name sortKey="Wingeier, B" uniqKey="Wingeier B">B. Wingeier</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Brown, P" uniqKey="Brown P">P. Brown</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Brown, P" uniqKey="Brown P">P. Brown</name>
</author>
<author><name sortKey="Eusebio, A" uniqKey="Eusebio A">A. Eusebio</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Charles, P D" uniqKey="Charles P">P.D. Charles</name>
</author>
<author><name sortKey="Van Blercom, N" uniqKey="Van Blercom N">N. Van Blercom</name>
</author>
<author><name sortKey="Krack, P" uniqKey="Krack P">P. Krack</name>
</author>
<author><name sortKey="Lee, S L" uniqKey="Lee S">S.L. Lee</name>
</author>
<author><name sortKey="Xie, J" uniqKey="Xie J">J. Xie</name>
</author>
<author><name sortKey="Besson, G" uniqKey="Besson G">G. Besson</name>
</author>
<author><name sortKey="Benabid, A L" uniqKey="Benabid A">A.L. Benabid</name>
</author>
<author><name sortKey="Pollak, P" uniqKey="Pollak P">P. Pollak</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chen, C C" uniqKey="Chen C">C.C. Chen</name>
</author>
<author><name sortKey="Pogosyan, A" uniqKey="Pogosyan A">A. Pogosyan</name>
</author>
<author><name sortKey="Zrinzo, L U" uniqKey="Zrinzo L">L.U. Zrinzo</name>
</author>
<author><name sortKey="Tisch, S" uniqKey="Tisch S">S. Tisch</name>
</author>
<author><name sortKey="Limousin, P" uniqKey="Limousin P">P. Limousin</name>
</author>
<author><name sortKey="Ashkan, K" uniqKey="Ashkan K">K. Ashkan</name>
</author>
<author><name sortKey="Yousry, T" uniqKey="Yousry T">T. Yousry</name>
</author>
<author><name sortKey="Hariz, M I" uniqKey="Hariz M">M.I. Hariz</name>
</author>
<author><name sortKey="Brown, P" uniqKey="Brown P">P. Brown</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chen, C C" uniqKey="Chen C">C.C. Chen</name>
</author>
<author><name sortKey="Brucke, C" uniqKey="Brucke C">C. Brucke</name>
</author>
<author><name sortKey="Kempf, F" uniqKey="Kempf F">F. Kempf</name>
</author>
<author><name sortKey="Kupsch, A" uniqKey="Kupsch A">A. Kupsch</name>
</author>
<author><name sortKey="Song Lu, C" uniqKey="Song Lu C">C. Song Lu</name>
</author>
<author><name sortKey="Tseng Lee, S" uniqKey="Tseng Lee S">S. Tseng Lee</name>
</author>
<author><name sortKey="Tisch, S" uniqKey="Tisch S">S. Tisch</name>
</author>
<author><name sortKey="Limousin, P" uniqKey="Limousin P">P. Limousin</name>
</author>
<author><name sortKey="Hariz, M" uniqKey="Hariz M">M. Hariz</name>
</author>
<author><name sortKey="Brown, P" uniqKey="Brown P">P. Brown</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Chen, C C" uniqKey="Chen C">C.C. Chen</name>
</author>
<author><name sortKey="Litvak, V" uniqKey="Litvak V">V. Litvak</name>
</author>
<author><name sortKey="Gilbertson, T" uniqKey="Gilbertson T">T. Gilbertson</name>
</author>
<author><name sortKey="Kuhn, A" uniqKey="Kuhn A">A. Kühn</name>
</author>
<author><name sortKey="Lu, C S" uniqKey="Lu C">C.S. Lu</name>
</author>
<author><name sortKey="Lee, S T" uniqKey="Lee S">S.T. Lee</name>
</author>
<author><name sortKey="Tsai, C H" uniqKey="Tsai C">C.H. Tsai</name>
</author>
<author><name sortKey="Tisch, S" uniqKey="Tisch S">S. Tisch</name>
</author>
<author><name sortKey="Limousin, P" uniqKey="Limousin P">P. Limousin</name>
</author>
<author><name sortKey="Hariz, M" uniqKey="Hariz M">M. Hariz</name>
</author>
<author><name sortKey="Brown, P" uniqKey="Brown P">P. Brown</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Costa, R M" uniqKey="Costa R">R.M. Costa</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Dorval, A D" uniqKey="Dorval A">A.D. Dorval</name>
</author>
<author><name sortKey="Russo, G S" uniqKey="Russo G">G.S. Russo</name>
</author>
<author><name sortKey="Hashimoto, T" uniqKey="Hashimoto T">T. Hashimoto</name>
</author>
<author><name sortKey="Xu, W" uniqKey="Xu W">W. Xu</name>
</author>
<author><name sortKey="Grill, W M" uniqKey="Grill W">W.M. Grill</name>
</author>
<author><name sortKey="Vitek, J L" uniqKey="Vitek J">J.L. Vitek</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Eusebio, A" uniqKey="Eusebio A">A. Eusebio</name>
</author>
<author><name sortKey="Chen, C C" uniqKey="Chen C">C.C. Chen</name>
</author>
<author><name sortKey="Lu, C S" uniqKey="Lu C">C.S. Lu</name>
</author>
<author><name sortKey="Lee, S T" uniqKey="Lee S">S.T. Lee</name>
</author>
<author><name sortKey="Tsai, C H" uniqKey="Tsai C">C.H. Tsai</name>
</author>
<author><name sortKey="Limousin, P" uniqKey="Limousin P">P. Limousin</name>
</author>
<author><name sortKey="Hariz, M" uniqKey="Hariz M">M. Hariz</name>
</author>
<author><name sortKey="Brown, P" uniqKey="Brown P">P. Brown</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Gubellini, P" uniqKey="Gubellini P">P. Gubellini</name>
</author>
<author><name sortKey="Eusebio, A" uniqKey="Eusebio A">A. Eusebio</name>
</author>
<author><name sortKey="Oueslati, A" uniqKey="Oueslati A">A. Oueslati</name>
</author>
<author><name sortKey="Melon, C" uniqKey="Melon C">C. Melon</name>
</author>
<author><name sortKey="Kerkerian Le Goff, L" uniqKey="Kerkerian Le Goff L">L. Kerkerian-Le Goff</name>
</author>
<author><name sortKey="Salin, P" uniqKey="Salin P">P. Salin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hammond, C" uniqKey="Hammond C">C. Hammond</name>
</author>
<author><name sortKey="Bergman, H" uniqKey="Bergman H">H. Bergman</name>
</author>
<author><name sortKey="Brown, P" uniqKey="Brown P">P. Brown</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Hammond, C" uniqKey="Hammond C">C. Hammond</name>
</author>
<author><name sortKey="Ammari, R" uniqKey="Ammari R">R. Ammari</name>
</author>
<author><name sortKey="Bioulac, B" uniqKey="Bioulac B">B. Bioulac</name>
</author>
<author><name sortKey="Garcia, L" uniqKey="Garcia L">L. Garcia</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Kuhn, A A" uniqKey="Kuhn A">A.A. Kühn</name>
</author>
<author><name sortKey="Kupsch, A" uniqKey="Kupsch A">A. Kupsch</name>
</author>
<author><name sortKey="Schneider, G H" uniqKey="Schneider G">G.-H. Schneider</name>
</author>
<author><name sortKey="Brown, P" uniqKey="Brown P">P. Brown</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kuhn, A A" uniqKey="Kuhn A">A.A. Kühn</name>
</author>
<author><name sortKey="Kempf, F" uniqKey="Kempf F">F. Kempf</name>
</author>
<author><name sortKey="Brucke, C" uniqKey="Brucke C">C. Brucke</name>
</author>
<author><name sortKey="Gaynor Doyle, L" uniqKey="Gaynor Doyle L">L. Gaynor Doyle</name>
</author>
<author><name sortKey="Martinez Torres, I" uniqKey="Martinez Torres I">I. Martinez-Torres</name>
</author>
<author><name sortKey="Pogosyan, A" uniqKey="Pogosyan A">A. Pogosyan</name>
</author>
<author><name sortKey="Trottenberg, T" uniqKey="Trottenberg T">T. Trottenberg</name>
</author>
<author><name sortKey="Kupsch, A" uniqKey="Kupsch A">A. Kupsch</name>
</author>
<author><name sortKey="Schneider, G H" uniqKey="Schneider G">G.-H. Schneider</name>
</author>
<author><name sortKey="Hariz, M I" uniqKey="Hariz M">M.I. Hariz</name>
</author>
<author><name sortKey="Vandenberghe, W" uniqKey="Vandenberghe W">W. Vandenberghe</name>
</author>
<author><name sortKey="Nuttin, B" uniqKey="Nuttin B">B. Nuttin</name>
</author>
<author><name sortKey="Brown, P" uniqKey="Brown P">P. Brown</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Kuhn, A A" uniqKey="Kuhn A">A.A. Kühn</name>
</author>
<author><name sortKey="Tsui, A" uniqKey="Tsui A">A. Tsui</name>
</author>
<author><name sortKey="Aziz, T" uniqKey="Aziz T">T. Aziz</name>
</author>
<author><name sortKey="Ray, N" uniqKey="Ray N">N. Ray</name>
</author>
<author><name sortKey="Brucke, C" uniqKey="Brucke C">C. Brücke</name>
</author>
<author><name sortKey="Kupsch, A" uniqKey="Kupsch A">A. Kupsch</name>
</author>
<author><name sortKey="Schneider, G H" uniqKey="Schneider G">G.-H. Schneider</name>
</author>
<author><name sortKey="Brown, P" uniqKey="Brown P">P. Brown</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lalo, E" uniqKey="Lalo E">E. Lalo</name>
</author>
<author><name sortKey="Thobois, S" uniqKey="Thobois S">S. Thobois</name>
</author>
<author><name sortKey="Sharott, S" uniqKey="Sharott S">S. Sharott</name>
</author>
<author><name sortKey="Polo, G" uniqKey="Polo G">G. Polo</name>
</author>
<author><name sortKey="Mertens, P" uniqKey="Mertens P">P. Mertens</name>
</author>
<author><name sortKey="Pogosyan, A" uniqKey="Pogosyan A">A. Pogosyan</name>
</author>
<author><name sortKey="Brown, P" uniqKey="Brown P">P. Brown</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Leblois, A" uniqKey="Leblois A">A. Leblois</name>
</author>
<author><name sortKey="Meissner, W" uniqKey="Meissner W">W. Meissner</name>
</author>
<author><name sortKey="Bioulac, B" uniqKey="Bioulac B">B. Bioulac</name>
</author>
<author><name sortKey="Gross, C E" uniqKey="Gross C">C.E. Gross</name>
</author>
<author><name sortKey="Hansel, D" uniqKey="Hansel D">D. Hansel</name>
</author>
<author><name sortKey="Boraud, T" uniqKey="Boraud T">T. Boraud</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mallet, N" uniqKey="Mallet N">N. Mallet</name>
</author>
<author><name sortKey="Pogosyan, A" uniqKey="Pogosyan A">A. Pogosyan</name>
</author>
<author><name sortKey="Sharott, A" uniqKey="Sharott A">A. Sharott</name>
</author>
<author><name sortKey="Csicsvari, J" uniqKey="Csicsvari J">J. Csicsvari</name>
</author>
<author><name sortKey="Bolam, J P" uniqKey="Bolam J">J.P. Bolam</name>
</author>
<author><name sortKey="Brown, P" uniqKey="Brown P">P. Brown</name>
</author>
<author><name sortKey="Magill, P J" uniqKey="Magill P">P.J. Magill</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mallet, N" uniqKey="Mallet N">N. Mallet</name>
</author>
<author><name sortKey="Pogosyan, A" uniqKey="Pogosyan A">A. Pogosyan</name>
</author>
<author><name sortKey="Marton, L F" uniqKey="Marton L">L.F. Márton</name>
</author>
<author><name sortKey="Bolam, J P" uniqKey="Bolam J">J.P. Bolam</name>
</author>
<author><name sortKey="Brown, P" uniqKey="Brown P">P. Brown</name>
</author>
<author><name sortKey="Magill, P J" uniqKey="Magill P">P.J. Magill</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Priori, A" uniqKey="Priori A">A. Priori</name>
</author>
<author><name sortKey="Ardolino, G" uniqKey="Ardolino G">G. Ardolino</name>
</author>
<author><name sortKey="Marceglia, S" uniqKey="Marceglia S">S. Marceglia</name>
</author>
<author><name sortKey="Mrakic Sposta, S" uniqKey="Mrakic Sposta S">S. Mrakic-Sposta</name>
</author>
<author><name sortKey="Locatelli, M" uniqKey="Locatelli M">M. Locatelli</name>
</author>
<author><name sortKey="Tamma, F" uniqKey="Tamma F">F. Tamma</name>
</author>
<author><name sortKey="Rossi, L" uniqKey="Rossi L">L. Rossi</name>
</author>
<author><name sortKey="Foffani, G" uniqKey="Foffani G">G. Foffani</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Rodriguez Oroz, M C" uniqKey="Rodriguez Oroz M">M.C. Rodriguez-Oroz</name>
</author>
<author><name sortKey="Obeso, J A" uniqKey="Obeso J">J.A. Obeso</name>
</author>
<author><name sortKey="Lang, A E" uniqKey="Lang A">A.E. Lang</name>
</author>
<author><name sortKey="Houeto, J L" uniqKey="Houeto J">J.L. Houeto</name>
</author>
<author><name sortKey="Pollak, P" uniqKey="Pollak P">P. Pollak</name>
</author>
<author><name sortKey="Rehncrona, S" uniqKey="Rehncrona S">S. Rehncrona</name>
</author>
<author><name sortKey="Kulisevsky, J" uniqKey="Kulisevsky J">J. Kulisevsky</name>
</author>
<author><name sortKey="Albanese, A" uniqKey="Albanese A">A. Albanese</name>
</author>
<author><name sortKey="Volkmann, J" uniqKey="Volkmann J">J. Volkmann</name>
</author>
<author><name sortKey="Hariz, M I" uniqKey="Hariz M">M.I. Hariz</name>
</author>
<author><name sortKey="Quinn, N P" uniqKey="Quinn N">N.P. Quinn</name>
</author>
<author><name sortKey="Speelman, J D" uniqKey="Speelman J">J.D. Speelman</name>
</author>
<author><name sortKey="Guridi, J" uniqKey="Guridi J">J. Guridi</name>
</author>
<author><name sortKey="Zamarbide, I" uniqKey="Zamarbide I">I. Zamarbide</name>
</author>
<author><name sortKey="Gironell, A" uniqKey="Gironell A">A. Gironell</name>
</author>
<author><name sortKey="Molet, J" uniqKey="Molet J">J. Molet</name>
</author>
<author><name sortKey="Pascual Sedano, B" uniqKey="Pascual Sedano B">B. Pascual-Sedano</name>
</author>
<author><name sortKey="Pidoux, B" uniqKey="Pidoux B">B. Pidoux</name>
</author>
<author><name sortKey="Bonnet, A M" uniqKey="Bonnet A">A.M. Bonnet</name>
</author>
<author><name sortKey="Agid, Y" uniqKey="Agid Y">Y. Agid</name>
</author>
<author><name sortKey="Xie, J" uniqKey="Xie J">J. Xie</name>
</author>
<author><name sortKey="Benabid, A L" uniqKey="Benabid A">A.L. Benabid</name>
</author>
<author><name sortKey="Lozano, A M" uniqKey="Lozano A">A.M. Lozano</name>
</author>
<author><name sortKey="Saint Cyr, J" uniqKey="Saint Cyr J">J. Saint-Cyr</name>
</author>
<author><name sortKey="Romito, L" uniqKey="Romito L">L. Romito</name>
</author>
<author><name sortKey="Contarino, M F" uniqKey="Contarino M">M.F. Contarino</name>
</author>
<author><name sortKey="Scerrati, M" uniqKey="Scerrati M">M. Scerrati</name>
</author>
<author><name sortKey="Fraix, V" uniqKey="Fraix V">V. Fraix</name>
</author>
<author><name sortKey="Van Blercom, N" uniqKey="Van Blercom N">N. Van Blercom</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rossi, L" uniqKey="Rossi L">L. Rossi</name>
</author>
<author><name sortKey="Foffani, G" uniqKey="Foffani G">G. Foffani</name>
</author>
<author><name sortKey="Marceglia, S" uniqKey="Marceglia S">S. Marceglia</name>
</author>
<author><name sortKey="Bracchi, F" uniqKey="Bracchi F">F. Bracchi</name>
</author>
<author><name sortKey="Barbieri, S" uniqKey="Barbieri S">S. Barbieri</name>
</author>
<author><name sortKey="Priori, A" uniqKey="Priori A">A. Priori</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Rossi, L" uniqKey="Rossi L">L. Rossi</name>
</author>
<author><name sortKey="Marceglia, S" uniqKey="Marceglia S">S. Marceglia</name>
</author>
<author><name sortKey="Foffani, G" uniqKey="Foffani G">G. Foffani</name>
</author>
<author><name sortKey="Cogiamanian, F" uniqKey="Cogiamanian F">F. Cogiamanian</name>
</author>
<author><name sortKey="Tamma, F" uniqKey="Tamma F">F. Tamma</name>
</author>
<author><name sortKey="Rampini, P" uniqKey="Rampini P">P. Rampini</name>
</author>
<author><name sortKey="Barbieri, S" uniqKey="Barbieri S">S. Barbieri</name>
</author>
<author><name sortKey="Bracchi, F" uniqKey="Bracchi F">F. Bracchi</name>
</author>
<author><name sortKey="Priori, A" uniqKey="Priori A">A. Priori</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sharott, A" uniqKey="Sharott A">A. Sharott</name>
</author>
<author><name sortKey="Magill, P J" uniqKey="Magill P">P.J. Magill</name>
</author>
<author><name sortKey="Harnack, D" uniqKey="Harnack D">D. Harnack</name>
</author>
<author><name sortKey="Kupsch, A" uniqKey="Kupsch A">A. Kupsch</name>
</author>
<author><name sortKey="Meissner, W" uniqKey="Meissner W">W. Meissner</name>
</author>
<author><name sortKey="Brown, P" uniqKey="Brown P">P. Brown</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Temperli, P" uniqKey="Temperli P">P. Temperli</name>
</author>
<author><name sortKey="Ghika, J" uniqKey="Ghika J">J. Ghika</name>
</author>
<author><name sortKey="Villemure, J G" uniqKey="Villemure J">J.G. Villemure</name>
</author>
<author><name sortKey="Burkhard, P R" uniqKey="Burkhard P">P.R. Burkhard</name>
</author>
<author><name sortKey="Bogousslavsky, J" uniqKey="Bogousslavsky J">J. Bogousslavsky</name>
</author>
<author><name sortKey="Vingerhoets, F J" uniqKey="Vingerhoets F">F.J. Vingerhoets</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Weinberger, M" uniqKey="Weinberger M">M. Weinberger</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Wingeier, B" uniqKey="Wingeier B">B. Wingeier</name>
</author>
<author><name sortKey="Tcheng, T" uniqKey="Tcheng T">T. Tcheng</name>
</author>
<author><name sortKey="Koop, M M" uniqKey="Koop M">M.M. Koop</name>
</author>
<author><name sortKey="Hill, B C" uniqKey="Hill B">B.C. Hill</name>
</author>
<author><name sortKey="Heit, G" uniqKey="Heit G">G. Heit</name>
</author>
<author><name sortKey="Bronte Stewart, H M" uniqKey="Bronte Stewart H">H.M. Bronte-Stewart</name>
</author>
</analytic>
</biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<pmc article-type="discussion"><pmc-dir>properties open_access</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Exp Neurol</journal-id>
<journal-id journal-id-type="iso-abbrev">Exp. Neurol</journal-id>
<journal-title-group><journal-title>Experimental Neurology</journal-title>
</journal-title-group>
<issn pub-type="ppub">0014-4886</issn>
<issn pub-type="epub">1090-2430</issn>
<publisher><publisher-name>Academic Press</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmid">19233172</article-id>
<article-id pub-id-type="pmc">2697315</article-id>
<article-id pub-id-type="publisher-id">S0014-4886(09)00055-7</article-id>
<article-id pub-id-type="doi">10.1016/j.expneurol.2009.02.003</article-id>
<article-categories><subj-group subj-group-type="heading"><subject>Commentary</subject>
</subj-group>
</article-categories>
<title-group><article-title>Synchronisation in the beta frequency-band — The bad boy of parkinsonism or an innocent bystander?</article-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Eusebio</surname>
<given-names>Alexandre</given-names>
</name>
<xref rid="aff1" ref-type="aff">a</xref>
<xref rid="aff2" ref-type="aff">b</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Brown</surname>
<given-names>Peter</given-names>
</name>
<email>p.brown@ion.ucl.ac.uk</email>
<xref rid="aff2" ref-type="aff">b</xref>
<xref rid="cor1" ref-type="corresp">⁎</xref>
</contrib>
</contrib-group>
<aff id="aff1"><label>a</label>
Department of Neurology and Movement Disorders, CHU Timone, Marseille, France</aff>
<aff id="aff2"><label>b</label>
Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, 33 Queen Square, London, WCIN 3BG, UK.</aff>
<author-notes><corresp id="cor1"><label>⁎</label>
Corresponding author. Fax: +44 (0)20 7278 9836. <email>p.brown@ion.ucl.ac.uk</email>
</corresp>
</author-notes>
<pub-date pub-type="pmc-release"><day>1</day>
<month>5</month>
<year>2009</year>
</pub-date>
<pmc-comment> PMC Release delay is 0 months and 0 days and was based on .</pmc-comment>
<pub-date pub-type="ppub"><month>5</month>
<year>2009</year>
</pub-date>
<volume>217</volume>
<issue>1</issue>
<fpage>1</fpage>
<lpage>3</lpage>
<history><date date-type="received"><day>25</day>
<month>11</month>
<year>2008</year>
</date>
<date date-type="rev-recd"><day>28</day>
<month>1</month>
<year>2009</year>
</date>
<date date-type="accepted"><day>11</day>
<month>2</month>
<year>2009</year>
</date>
</history>
<permissions><copyright-statement>© 2009 Elsevier Inc.</copyright-statement>
<copyright-year>2009</copyright-year>
<copyright-holder>Elsevier Inc.</copyright-holder>
<license xlink:href="https://creativecommons.org/licenses/by/3.0/"><license-p>Open Access under <ext-link ext-link-type="uri" xlink:href="https://creativecommons.org/licenses/by/3.0/">CC BY 3.0</ext-link>
license</license-p>
</license>
</permissions>
<abstract><p>Excessive synchronisation of basal ganglia neuronal activity in the beta frequency band has been implicated in Parkinson's disease. In a recent issue of Experimental Neurology, Bronte-Stewart, H., Barberini, C., Koop, M.M., Hill, B.C., Henderson, J.M., Wingeier, B., 2009. The STN beta-band profile in Parkinson's disease is stationary and shows prolonged attenuation after deep brain stimulation. Exp. Neurol. 215, 20–28. demonstrate that such activity is consistent over time and provide further evidence that deep brain stimulation is associated with its suppression. However, the extent to which beta synchrony has a mechanistic (rather than epiphenomenal) role in parkinsonism remains unclear, and the suppression of this activity by deep brain stimulation is contentious. This commentary discusses the evidence for and against a role for excessive beta synchrony in mediating the parkinsonian phenotype and in providing a possible mechanism to explain the therapeutic effects of deep brain stimulation in Parkinson's disease.</p>
</abstract>
</article-meta>
</front>
</pmc>
<affiliations><list><country><li>France</li>
<li>Royaume-Uni</li>
</country>
<region><li>Provence-Alpes-Côte d'Azur</li>
</region>
<settlement><li>Marseille</li>
</settlement>
</list>
<tree><country name="France"><region name="Provence-Alpes-Côte d'Azur"><name sortKey="Eusebio, Alexandre" sort="Eusebio, Alexandre" uniqKey="Eusebio A" first="Alexandre" last="Eusebio">Alexandre Eusebio</name>
</region>
</country>
<country name="Royaume-Uni"><noRegion><name sortKey="Eusebio, Alexandre" sort="Eusebio, Alexandre" uniqKey="Eusebio A" first="Alexandre" last="Eusebio">Alexandre Eusebio</name>
</noRegion>
<name sortKey="Brown, Peter" sort="Brown, Peter" uniqKey="Brown P" first="Peter" last="Brown">Peter Brown</name>
</country>
</tree>
</affiliations>
</record>
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