La maladie de Parkinson en France (serveur d'exploration)

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Pathological Gambling Associated With Aripiprazole or Dopamine Replacement Therapy

Identifieur interne : 000170 ( Pmc/Checkpoint ); précédent : 000169; suivant : 000171

Pathological Gambling Associated With Aripiprazole or Dopamine Replacement Therapy

Auteurs : Marie Grall-Bronnec [France] ; Anne Sauvaget [France] ; Fanny Perrouin [France] ; Juliette Leboucher [France] ; François Etcheverrigaray [France] ; Gaëlle Challet-Bouju [France] ; Louise Gaboriau [France] ; Pascal Derkinderen [France] ; Pascale Jolliet [France] ; Caroline Victorri-Vigneau [France]

Source :

RBID : PMC:4700874

Abstract

Supplemental digital content is available in the text.


Url:
DOI: 10.1097/JCP.0000000000000444
PubMed: 26658263
PubMed Central: 4700874


Affiliations:


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PMC:4700874

Le document en format XML

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<nlm:aff id="aff1">From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes, France.</nlm:aff>
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<nlm:aff id="aff1">From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes, France.</nlm:aff>
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<wicri:regionArea>From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes</wicri:regionArea>
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<name sortKey="Etcheverrigaray, Francois" sort="Etcheverrigaray, Francois" uniqKey="Etcheverrigaray F" first="François" last="Etcheverrigaray">François Etcheverrigaray</name>
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<nlm:aff id="aff1">From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes, France.</nlm:aff>
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<wicri:regionArea>From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes</wicri:regionArea>
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<nlm:aff id="aff1">From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes, France.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes</wicri:regionArea>
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<nlm:aff id="aff1">From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes, France.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes</wicri:regionArea>
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<nlm:aff id="aff1">From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes, France.</nlm:aff>
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<wicri:regionArea>From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes</wicri:regionArea>
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<name sortKey="Jolliet, Pascale" sort="Jolliet, Pascale" uniqKey="Jolliet P" first="Pascale" last="Jolliet">Pascale Jolliet</name>
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<nlm:aff id="aff1">From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes, France.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes</wicri:regionArea>
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<name sortKey="Victorri Vigneau, Caroline" sort="Victorri Vigneau, Caroline" uniqKey="Victorri Vigneau C" first="Caroline" last="Victorri-Vigneau">Caroline Victorri-Vigneau</name>
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<nlm:aff id="aff1">From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes, France.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes</wicri:regionArea>
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<title xml:lang="en" level="a" type="main">Pathological Gambling Associated With Aripiprazole or Dopamine Replacement Therapy</title>
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<name sortKey="Grall Bronnec, Marie" sort="Grall Bronnec, Marie" uniqKey="Grall Bronnec M" first="Marie" last="Grall-Bronnec">Marie Grall-Bronnec</name>
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<nlm:aff id="aff1">From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes, France.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes</wicri:regionArea>
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<name sortKey="Sauvaget, Anne" sort="Sauvaget, Anne" uniqKey="Sauvaget A" first="Anne" last="Sauvaget">Anne Sauvaget</name>
<affiliation wicri:level="3">
<nlm:aff id="aff1">From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes, France.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes</wicri:regionArea>
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<name sortKey="Perrouin, Fanny" sort="Perrouin, Fanny" uniqKey="Perrouin F" first="Fanny" last="Perrouin">Fanny Perrouin</name>
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<nlm:aff id="aff1">From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes, France.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes</wicri:regionArea>
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<nlm:aff id="aff1">From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes, France.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes</wicri:regionArea>
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<name sortKey="Etcheverrigaray, Francois" sort="Etcheverrigaray, Francois" uniqKey="Etcheverrigaray F" first="François" last="Etcheverrigaray">François Etcheverrigaray</name>
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<nlm:aff id="aff1">From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes, France.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes</wicri:regionArea>
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<name sortKey="Challet Bouju, Gaelle" sort="Challet Bouju, Gaelle" uniqKey="Challet Bouju G" first="Gaëlle" last="Challet-Bouju">Gaëlle Challet-Bouju</name>
<affiliation wicri:level="3">
<nlm:aff id="aff1">From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes, France.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes</wicri:regionArea>
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<name sortKey="Gaboriau, Louise" sort="Gaboriau, Louise" uniqKey="Gaboriau L" first="Louise" last="Gaboriau">Louise Gaboriau</name>
<affiliation wicri:level="3">
<nlm:aff id="aff1">From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes, France.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes</wicri:regionArea>
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<region type="region">Pays de la Loire</region>
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<name sortKey="Derkinderen, Pascal" sort="Derkinderen, Pascal" uniqKey="Derkinderen P" first="Pascal" last="Derkinderen">Pascal Derkinderen</name>
<affiliation wicri:level="3">
<nlm:aff id="aff1">From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes, France.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes</wicri:regionArea>
<placeName>
<region type="region">Pays de la Loire</region>
<region type="old region">Pays de la Loire</region>
<settlement type="city">Nantes</settlement>
</placeName>
</affiliation>
</author>
<author>
<name sortKey="Jolliet, Pascale" sort="Jolliet, Pascale" uniqKey="Jolliet P" first="Pascale" last="Jolliet">Pascale Jolliet</name>
<affiliation wicri:level="3">
<nlm:aff id="aff1">From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes, France.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes</wicri:regionArea>
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<region type="region">Pays de la Loire</region>
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<name sortKey="Victorri Vigneau, Caroline" sort="Victorri Vigneau, Caroline" uniqKey="Victorri Vigneau C" first="Caroline" last="Victorri-Vigneau">Caroline Victorri-Vigneau</name>
<affiliation wicri:level="3">
<nlm:aff id="aff1">From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes, France.</nlm:aff>
<country xml:lang="fr" wicri:curation="lc">France</country>
<wicri:regionArea>From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes</wicri:regionArea>
<placeName>
<region type="region">Pays de la Loire</region>
<region type="old region">Pays de la Loire</region>
<settlement type="city">Nantes</settlement>
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</author>
</analytic>
<series>
<title level="j">Journal of Clinical Psychopharmacology</title>
<idno type="ISSN">0271-0749</idno>
<idno type="eISSN">1533-712X</idno>
<imprint>
<date when="2015">2015</date>
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<front>
<div type="abstract" xml:lang="en">
<p>Supplemental digital content is available in the text.</p>
</div>
</front>
<back>
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<pmc article-type="review-article">
<pmc-dir>properties open_access</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">J Clin Psychopharmacol</journal-id>
<journal-id journal-id-type="iso-abbrev">J Clin Psychopharmacol</journal-id>
<journal-id journal-id-type="publisher-id">JCP</journal-id>
<journal-title-group>
<journal-title>Journal of Clinical Psychopharmacology</journal-title>
</journal-title-group>
<issn pub-type="ppub">0271-0749</issn>
<issn pub-type="epub">1533-712X</issn>
<publisher>
<publisher-name>Lippincott Williams & Wilkins</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">26658263</article-id>
<article-id pub-id-type="pmc">4700874</article-id>
<article-id pub-id-type="publisher-id">JCP50118</article-id>
<article-id pub-id-type="doi">10.1097/JCP.0000000000000444</article-id>
<article-id pub-id-type="art-access-id">00011</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Review Articles</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Pathological Gambling Associated With Aripiprazole or Dopamine Replacement Therapy</article-title>
<subtitle>Do Patients Share the Same Features? A Review</subtitle>
</title-group>
<contrib-group>
<contrib contrib-type="author">
<name>
<surname>Grall-Bronnec</surname>
<given-names>Marie</given-names>
</name>
<degrees>MD, PhD</degrees>
<xref ref-type="aff" rid="aff1">*†</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Sauvaget</surname>
<given-names>Anne</given-names>
</name>
<degrees>MD, PhD</degrees>
<xref ref-type="aff" rid="aff1">*</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Perrouin</surname>
<given-names>Fanny</given-names>
</name>
<degrees>PharmD</degrees>
<xref ref-type="aff" rid="aff1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Leboucher</surname>
<given-names>Juliette</given-names>
</name>
<degrees>MSc</degrees>
<xref ref-type="aff" rid="aff1">*</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Etcheverrigaray</surname>
<given-names>François</given-names>
</name>
<degrees>PharmD</degrees>
<xref ref-type="aff" rid="aff1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Challet-Bouju</surname>
<given-names>Gaëlle</given-names>
</name>
<degrees>PhD</degrees>
<xref ref-type="aff" rid="aff1">*†</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Gaboriau</surname>
<given-names>Louise</given-names>
</name>
<degrees>PharmD, MSc</degrees>
<xref ref-type="aff" rid="aff1"></xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Derkinderen</surname>
<given-names>Pascal</given-names>
</name>
<degrees>MD, PhD</degrees>
<xref ref-type="aff" rid="aff1">§</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Jolliet</surname>
<given-names>Pascale</given-names>
</name>
<degrees>MD, PhD</degrees>
<xref ref-type="aff" rid="aff1">†‡</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Victorri-Vigneau</surname>
<given-names>Caroline</given-names>
</name>
<degrees>PharmD, PhD</degrees>
<xref ref-type="aff" rid="aff1">†‡</xref>
</contrib>
</contrib-group>
<aff id="aff1">From the *Clinical Investigation Unit, “Behavioral Addictions/Complex Affective Disorders,” Department of Addictology and Psychiatry, CHU Nantes; †EA 4275 “Biostatistics, Pharmacoepidemiology, and Subjective Measures in Health Sciences,” Université Nantes; Departments of ‡Pharmacology, and §Neurology, CHU Nantes, Nantes, France.</aff>
<author-notes>
<corresp id="cor1">Reprints: Caroline Victorri-Vigneau, PharmD, PhD, Centre d'Evaluation et d'Information sur la Pharmacodépendance, Service de Pharmacologie Clinique, Institut de Biologie, 9, quai Moncousu, 44093 Nantes Cedex, France (e-mail:
<email>caroline.vigneau@chu-nantes.fr</email>
).</corresp>
</author-notes>
<pub-date pub-type="ppub">
<month>2</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="epub">
<day>29</day>
<month>12</month>
<year>2015</year>
</pub-date>
<volume>36</volume>
<issue>1</issue>
<fpage>63</fpage>
<lpage>70</lpage>
<history>
<date date-type="received">
<day>1</day>
<month>10</month>
<year>2014</year>
</date>
<date date-type="accepted">
<day>7</day>
<month>9</month>
<year>2015</year>
</date>
</history>
<permissions>
<copyright-statement>Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved</copyright-statement>
<copyright-year>2015</copyright-year>
<copyright-holder>Wolters Kluwer Health, Inc. All rights reserved.</copyright-holder>
<license>
<license-p>This is an open-access article distributed under the terms of the
<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc-nd/4.0/">Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND)</ext-link>
, where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially.</license-p>
</license>
</permissions>
<self-uri xlink:type="simple" xlink:href="jcp-36-63.pdf"></self-uri>
<abstract abstract-type="toc">
<p>Supplemental digital content is available in the text.</p>
</abstract>
<abstract>
<title>Background</title>
<p>In the last 10 years, dopamine replacement therapy (DRT) has become a well-known risk factor for developing an impulse control disorder, such as gambling disorder (GD). Another medication, aripiprazole (ARI), has been more recently identified as another risk factor. Dopamine replacement therapy and ARI share a dopamine agonist action. Our work aimed at comparing patients with PG according to their treatment with DRT or ARI.</p>
<sec>
<title>Methods</title>
<p>Two methods were combined—a systematic review concentrated on case reports and the analysis of a French disordered gamblers cohort focused on patients using ARI or DRT at inclusion.</p>
</sec>
<sec>
<title>Results</title>
<p>We reported 48 cases of GD possibly due to DRT and 17 cases of GD possibly due to ARI. Because of their standardized assessment, only the EVALJEU patients could be compared. Two clinical patterns emerged. Patients in the ARI group were young, impulsive, and high novelty seekers and had a history of substance misuse. Their first gambling experience occurred during adolescence. Conversely, patients in the DRT group were old, and they began gambling late in life. They showed low levels of gambling-related cognition.</p>
</sec>
<sec>
<title>Conclusions</title>
<p>Patients in the ARI group seemed to be more severe pathological gamblers than patients in the DRT group. Aripiprazole is a partial D
<sub>2</sub>
receptor agonist, whereas DRT includes full D
<sub>2</sub>
receptor agonist. The trigger mechanism of PG development is complex and cannot only be attributed only to the pharmacodynamic effects of dopaminergic drugs. Indeed, individual vulnerability factors and environmental factors need to be considered.</p>
</sec>
</abstract>
<kwd-group>
<title>Key Words</title>
<kwd>aripiprazole</kwd>
<kwd>dopamine replacement therapy</kwd>
<kwd>gambling disorder</kwd>
<kwd>impulse control disorder</kwd>
<kwd>agonist</kwd>
<kwd>dopamine receptor</kwd>
</kwd-group>
<custom-meta-group>
<custom-meta>
<meta-name>OPEN-ACCESS</meta-name>
<meta-value>TRUE</meta-value>
</custom-meta>
<custom-meta>
<meta-name>SDC</meta-name>
<meta-value>T</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
<affiliations>
<list>
<country>
<li>France</li>
</country>
<region>
<li>Pays de la Loire</li>
</region>
<settlement>
<li>Nantes</li>
</settlement>
</list>
<tree>
<country name="France">
<region name="Pays de la Loire">
<name sortKey="Grall Bronnec, Marie" sort="Grall Bronnec, Marie" uniqKey="Grall Bronnec M" first="Marie" last="Grall-Bronnec">Marie Grall-Bronnec</name>
</region>
<name sortKey="Challet Bouju, Gaelle" sort="Challet Bouju, Gaelle" uniqKey="Challet Bouju G" first="Gaëlle" last="Challet-Bouju">Gaëlle Challet-Bouju</name>
<name sortKey="Derkinderen, Pascal" sort="Derkinderen, Pascal" uniqKey="Derkinderen P" first="Pascal" last="Derkinderen">Pascal Derkinderen</name>
<name sortKey="Etcheverrigaray, Francois" sort="Etcheverrigaray, Francois" uniqKey="Etcheverrigaray F" first="François" last="Etcheverrigaray">François Etcheverrigaray</name>
<name sortKey="Gaboriau, Louise" sort="Gaboriau, Louise" uniqKey="Gaboriau L" first="Louise" last="Gaboriau">Louise Gaboriau</name>
<name sortKey="Jolliet, Pascale" sort="Jolliet, Pascale" uniqKey="Jolliet P" first="Pascale" last="Jolliet">Pascale Jolliet</name>
<name sortKey="Leboucher, Juliette" sort="Leboucher, Juliette" uniqKey="Leboucher J" first="Juliette" last="Leboucher">Juliette Leboucher</name>
<name sortKey="Perrouin, Fanny" sort="Perrouin, Fanny" uniqKey="Perrouin F" first="Fanny" last="Perrouin">Fanny Perrouin</name>
<name sortKey="Sauvaget, Anne" sort="Sauvaget, Anne" uniqKey="Sauvaget A" first="Anne" last="Sauvaget">Anne Sauvaget</name>
<name sortKey="Victorri Vigneau, Caroline" sort="Victorri Vigneau, Caroline" uniqKey="Victorri Vigneau C" first="Caroline" last="Victorri-Vigneau">Caroline Victorri-Vigneau</name>
</country>
</tree>
</affiliations>
</record>

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