Mitochondrial respiratory failure in skeletal muscle from patients with Parkinson's disease and multiple system atrophy
Identifieur interne : 001704 ( PascalFrancis/Curation ); précédent : 001703; suivant : 001705Mitochondrial respiratory failure in skeletal muscle from patients with Parkinson's disease and multiple system atrophy
Auteurs : O. Blin [France] ; C. Desnuelle ; O. Rascol ; M. Borg ; H. Peyro Saint Paul ; J. P. Azulay [France] ; F. Bille [France] ; D. Figarella [France] ; F. Coulom [France] ; J. F. Pellissier [France] ; J. L. Montastruc ; M. Chatel ; G. Serratrice [France]Source :
- Journal of the neurological sciences [ 0022-510X ] ; 1994.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
Abstract
We studied mitochondrial respiratory chain function in skeletal muscle taken from 27 patients with idiopathic Parkinson's disease (PD; 21 Dopa-treated PD patients and 6 de novo patients), 5 patients with multiple system atrophy (MSA) and from 43 age-matched controls in order to determine the occurrence of mitochondrial respiratory chain abnormalities in parkinsonian syndromes. In our control subjects, we found a significant age-related decrease in the activity of respiratory chain complex I. As compared to carefully age-matched control subjects, activity of complex (NADH: ubiquinone reductase) was significantly lower in muscle mitochondria from patients with PD and MSA and a mean remaining activity <30% of controls was observed
pA |
|
---|
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: Pour aller vers cette notice dans l'étape Curation :001948
Links to Exploration step
Pascal:94-0624765Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Mitochondrial respiratory failure in skeletal muscle from patients with Parkinson's disease and multiple system atrophy</title>
<author><name sortKey="Blin, O" sort="Blin, O" uniqKey="Blin O" first="O." last="Blin">O. Blin</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>CHU Timone, pharmacologie médicale clin. CPCET</s1>
<s2>13385 Marseille</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Desnuelle, C" sort="Desnuelle, C" uniqKey="Desnuelle C" first="C." last="Desnuelle">C. Desnuelle</name>
</author>
<author><name sortKey="Rascol, O" sort="Rascol, O" uniqKey="Rascol O" first="O." last="Rascol">O. Rascol</name>
</author>
<author><name sortKey="Borg, M" sort="Borg, M" uniqKey="Borg M" first="M." last="Borg">M. Borg</name>
</author>
<author><name sortKey="Peyro Saint Paul, H" sort="Peyro Saint Paul, H" uniqKey="Peyro Saint Paul H" first="H." last="Peyro Saint Paul">H. Peyro Saint Paul</name>
</author>
<author><name sortKey="Azulay, J P" sort="Azulay, J P" uniqKey="Azulay J" first="J. P." last="Azulay">J. P. Azulay</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>CHU Timone, clin. maladies systèmes nerveux appareil locomoteur</s1>
<s2>13385 Marseille</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Bille, F" sort="Bille, F" uniqKey="Bille F" first="F." last="Bille">F. Bille</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>CHU Timone, clin. maladies systèmes nerveux appareil locomoteur</s1>
<s2>13385 Marseille</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Figarella, D" sort="Figarella, D" uniqKey="Figarella D" first="D." last="Figarella">D. Figarella</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>CHU Timone, dép. neuropathologie</s1>
<s2>13385 Marseille</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Coulom, F" sort="Coulom, F" uniqKey="Coulom F" first="F." last="Coulom">F. Coulom</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>CHU Timone, clin. maladies systèmes nerveux appareil locomoteur</s1>
<s2>13385 Marseille</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Pellissier, J F" sort="Pellissier, J F" uniqKey="Pellissier J" first="J. F." last="Pellissier">J. F. Pellissier</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>CHU Timone, dép. neuropathologie</s1>
<s2>13385 Marseille</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Montastruc, J L" sort="Montastruc, J L" uniqKey="Montastruc J" first="J. L." last="Montastruc">J. L. Montastruc</name>
</author>
<author><name sortKey="Chatel, M" sort="Chatel, M" uniqKey="Chatel M" first="M." last="Chatel">M. Chatel</name>
</author>
<author><name sortKey="Serratrice, G" sort="Serratrice, G" uniqKey="Serratrice G" first="G." last="Serratrice">G. Serratrice</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>CHU Timone, clin. maladies systèmes nerveux appareil locomoteur</s1>
<s2>13385 Marseille</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">94-0624765</idno>
<date when="1994">1994</date>
<idno type="stanalyst">PASCAL 94-0624765 INIST</idno>
<idno type="RBID">Pascal:94-0624765</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">001948</idno>
<idno type="wicri:Area/PascalFrancis/Curation">001704</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Mitochondrial respiratory failure in skeletal muscle from patients with Parkinson's disease and multiple system atrophy</title>
<author><name sortKey="Blin, O" sort="Blin, O" uniqKey="Blin O" first="O." last="Blin">O. Blin</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>CHU Timone, pharmacologie médicale clin. CPCET</s1>
<s2>13385 Marseille</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Desnuelle, C" sort="Desnuelle, C" uniqKey="Desnuelle C" first="C." last="Desnuelle">C. Desnuelle</name>
</author>
<author><name sortKey="Rascol, O" sort="Rascol, O" uniqKey="Rascol O" first="O." last="Rascol">O. Rascol</name>
</author>
<author><name sortKey="Borg, M" sort="Borg, M" uniqKey="Borg M" first="M." last="Borg">M. Borg</name>
</author>
<author><name sortKey="Peyro Saint Paul, H" sort="Peyro Saint Paul, H" uniqKey="Peyro Saint Paul H" first="H." last="Peyro Saint Paul">H. Peyro Saint Paul</name>
</author>
<author><name sortKey="Azulay, J P" sort="Azulay, J P" uniqKey="Azulay J" first="J. P." last="Azulay">J. P. Azulay</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>CHU Timone, clin. maladies systèmes nerveux appareil locomoteur</s1>
<s2>13385 Marseille</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Bille, F" sort="Bille, F" uniqKey="Bille F" first="F." last="Bille">F. Bille</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>CHU Timone, clin. maladies systèmes nerveux appareil locomoteur</s1>
<s2>13385 Marseille</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Figarella, D" sort="Figarella, D" uniqKey="Figarella D" first="D." last="Figarella">D. Figarella</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>CHU Timone, dép. neuropathologie</s1>
<s2>13385 Marseille</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Coulom, F" sort="Coulom, F" uniqKey="Coulom F" first="F." last="Coulom">F. Coulom</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>CHU Timone, clin. maladies systèmes nerveux appareil locomoteur</s1>
<s2>13385 Marseille</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Pellissier, J F" sort="Pellissier, J F" uniqKey="Pellissier J" first="J. F." last="Pellissier">J. F. Pellissier</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>CHU Timone, dép. neuropathologie</s1>
<s2>13385 Marseille</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Montastruc, J L" sort="Montastruc, J L" uniqKey="Montastruc J" first="J. L." last="Montastruc">J. L. Montastruc</name>
</author>
<author><name sortKey="Chatel, M" sort="Chatel, M" uniqKey="Chatel M" first="M." last="Chatel">M. Chatel</name>
</author>
<author><name sortKey="Serratrice, G" sort="Serratrice, G" uniqKey="Serratrice G" first="G." last="Serratrice">G. Serratrice</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>CHU Timone, clin. maladies systèmes nerveux appareil locomoteur</s1>
<s2>13385 Marseille</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Journal of the neurological sciences</title>
<title level="j" type="abbreviated">J. neurol. sci.</title>
<idno type="ISSN">0022-510X</idno>
<imprint><date when="1994">1994</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Journal of the neurological sciences</title>
<title level="j" type="abbreviated">J. neurol. sci.</title>
<idno type="ISSN">0022-510X</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Exploration</term>
<term>Human</term>
<term>Mitochondria</term>
<term>Multiple system atrophy</term>
<term>Parkinson disease</term>
<term>Respiratory chain</term>
<term>Striated muscle</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Parkinson maladie</term>
<term>Chaîne respiratoire</term>
<term>Mitochondrie</term>
<term>Muscle strié</term>
<term>Exploration</term>
<term>Homme</term>
<term>Atrophie multisystématisée</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">We studied mitochondrial respiratory chain function in skeletal muscle taken from 27 patients with idiopathic Parkinson's disease (PD; 21 Dopa-treated PD patients and 6 de novo patients), 5 patients with multiple system atrophy (MSA) and from 43 age-matched controls in order to determine the occurrence of mitochondrial respiratory chain abnormalities in parkinsonian syndromes. In our control subjects, we found a significant age-related decrease in the activity of respiratory chain complex I. As compared to carefully age-matched control subjects, activity of complex (NADH: ubiquinone reductase) was significantly lower in muscle mitochondria from patients with PD and MSA and a mean remaining activity <30% of controls was observed</div>
</front>
</TEI>
<inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0022-510X</s0>
</fA01>
<fA02 i1="01"><s0>JNSCAG</s0>
</fA02>
<fA03 i2="1"><s0>J. neurol. sci.</s0>
</fA03>
<fA05><s2>125</s2>
</fA05>
<fA06><s2>1</s2>
</fA06>
<fA08 i1="01" i2="1" l="ENG"><s1>Mitochondrial respiratory failure in skeletal muscle from patients with Parkinson's disease and multiple system atrophy</s1>
</fA08>
<fA11 i1="01" i2="1"><s1>BLIN (O.)</s1>
</fA11>
<fA11 i1="02" i2="1"><s1>DESNUELLE (C.)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>RASCOL (O.)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>BORG (M.)</s1>
</fA11>
<fA11 i1="05" i2="1"><s1>PEYRO SAINT PAUL (H.)</s1>
</fA11>
<fA11 i1="06" i2="1"><s1>AZULAY (J. P.)</s1>
</fA11>
<fA11 i1="07" i2="1"><s1>BILLE (F.)</s1>
</fA11>
<fA11 i1="08" i2="1"><s1>FIGARELLA (D.)</s1>
</fA11>
<fA11 i1="09" i2="1"><s1>COULOM (F.)</s1>
</fA11>
<fA11 i1="10" i2="1"><s1>PELLISSIER (J. F.)</s1>
</fA11>
<fA11 i1="11" i2="1"><s1>MONTASTRUC (J. L.)</s1>
</fA11>
<fA11 i1="12" i2="1"><s1>CHATEL (M.)</s1>
</fA11>
<fA11 i1="13" i2="1"><s1>SERRATRICE (G.)</s1>
</fA11>
<fA14 i1="01"><s1>CHU Timone, pharmacologie médicale clin. CPCET</s1>
<s2>13385 Marseille</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>CHU Timone, clin. maladies systèmes nerveux appareil locomoteur</s1>
<s2>13385 Marseille</s2>
<s3>FRA</s3>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>13 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>CHU Timone, dép. neuropathologie</s1>
<s2>13385 Marseille</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
<sZ>10 aut.</sZ>
</fA14>
<fA20><s1>95-101</s1>
</fA20>
<fA21><s1>1994</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
<fA43 i1="01"><s1>INIST</s1>
<s2>12185</s2>
<s5>354000040309130160</s5>
</fA43>
<fA44><s0>0000</s0>
</fA44>
<fA45><s0>1 p.</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>94-0624765</s0>
</fA47>
<fA60><s1>P</s1>
</fA60>
<fA61><s0>A</s0>
</fA61>
<fA64 i1="01" i2="1"><s0>Journal of the neurological sciences</s0>
</fA64>
<fA66 i1="01"><s0>NLD</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>We studied mitochondrial respiratory chain function in skeletal muscle taken from 27 patients with idiopathic Parkinson's disease (PD; 21 Dopa-treated PD patients and 6 de novo patients), 5 patients with multiple system atrophy (MSA) and from 43 age-matched controls in order to determine the occurrence of mitochondrial respiratory chain abnormalities in parkinsonian syndromes. In our control subjects, we found a significant age-related decrease in the activity of respiratory chain complex I. As compared to carefully age-matched control subjects, activity of complex (NADH: ubiquinone reductase) was significantly lower in muscle mitochondria from patients with PD and MSA and a mean remaining activity <30% of controls was observed</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B17G</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Parkinson maladie</s0>
<s2>NM</s2>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Parkinson disease</s0>
<s2>NM</s2>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Parkinson enfermedad</s0>
<s2>NM</s2>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Chaîne respiratoire</s0>
<s5>04</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Respiratory chain</s0>
<s5>04</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Cadena respiratoria</s0>
<s5>04</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Mitochondrie</s0>
<s5>07</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Mitochondria</s0>
<s5>07</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Mitocondria</s0>
<s5>07</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Muscle strié</s0>
<s5>16</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Striated muscle</s0>
<s5>16</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Músculo estriado</s0>
<s5>16</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Exploration</s0>
<s5>17</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Exploration</s0>
<s5>17</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Exploración</s0>
<s5>17</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Homme</s0>
<s5>20</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Human</s0>
<s5>20</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Hombre</s0>
<s5>20</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Atrophie multisystématisée</s0>
<s2>NM</s2>
<s4>CD</s4>
<s5>96</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Multiple system atrophy</s0>
<s2>NM</s2>
<s4>CD</s4>
<s5>96</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Système nerveux pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Nervous system diseases</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Sistema nervioso patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Système nerveux central pathologie</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Central nervous system disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Encéphale pathologie</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Cerebral disorder</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Encéfalo patología</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Extrapyramidal syndrome</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0>
<s5>40</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0>
<s5>40</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Maladie dégénérative</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Degenerative disease</s0>
<s5>41</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Enfermedad degenerativa</s0>
<s5>41</s5>
</fC07>
<fN21><s1>300</s1>
</fN21>
</pA>
</standard>
</inist>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/PascalFrancis/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001704 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Curation/biblio.hfd -nk 001704 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= ParkinsonFranceV1 |flux= PascalFrancis |étape= Curation |type= RBID |clé= Pascal:94-0624765 |texte= Mitochondrial respiratory failure in skeletal muscle from patients with Parkinson's disease and multiple system atrophy }}
![]() | This area was generated with Dilib version V0.6.29. | ![]() |