ParkinsonFranceV1, PascalFrancis, Curation, bibRecord, 001156

Coordinated Reset Has Sustained Aftereffects in Parkinsonian Monkeys

Identifieur interne : 001156 ( PascalFrancis/Curation ); précédent : 001155; suivant : 001157

Coordinated Reset Has Sustained Aftereffects in Parkinsonian Monkeys

Auteurs : Peter A. Tass [Allemagne] ; LI QIN [République populaire de Chine, Royaume-Uni] ; Christian Hauptmann [Allemagne] ; Sandra Dovero [France] ; Erwan Bezard [République populaire de Chine, Royaume-Uni, France] ; Thomas Boraud [France] ; Wassilios G. Meissner [France]

Source :

Annals of neurology [ 0364-5134 ] ; 2012.

RBID : Pascal:13-0070325

Descripteurs français

Pascal (Inist)
- Maladie de Parkinson, Pathologie du système nerveux, Animal, Singe.
Wicri :
- topic : Singe.

English descriptors

KwdEn :
- Animal, Monkey, Nervous system diseases, Parkinson disease.

Abstract

Coordinated reset neuromodulation consists of the application of consecutive brief high-frequency pulse trains through the different contacts of the stimulation electrode. In theoretical studies, by achieving unlearning of abnormal connectivity between neurons, coordinated reset neuromodulation reduces pathological synchronization, a hallmark feature of Parkinson's disease pathophysiology. Here we show that coordinated reset neuromodulation of the subthalamic nucleus has both acute and sustained long-lasting aftereffects on motor function in parkinsonian nonhuman primates. Long-lasting aftereffects were not observed with classical deep brain stimulation. These observations encourage further development of coordinated reset neuromodulation for treating motor symptoms in Parkinson disease patients.

A01	`01`	`1`		`@0 0364-5134`
A02	`01`			`@0 ANNED3`
A03		`1`		`@0 Ann. neurol.`
A05				`@2 72`
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A08	`01`	`1`	`ENG`	`@1 Coordinated Reset Has Sustained Aftereffects in Parkinsonian Monkeys`
A11	`01`	`1`		`@1 TASS (Peter A.)`
A11	`02`	`1`		`@1 LI QIN`
A11	`03`	`1`		`@1 HAUPTMANN (Christian)`
A11	`04`	`1`		`@1 DOVERO (Sandra)`
A11	`05`	`1`		`@1 BEZARD (Erwan)`
A11	`06`	`1`		`@1 BORAUD (Thomas)`
A11	`07`	`1`		`@1 MEISSNER (Wassilios G.)`
A14	`01`			`@1 Institute for Medicine and Neurosciences, Research Center Jülich @2 Jülich @3 DEU @Z 1 aut. @Z 3 aut.`
A14	`02`			`@1 Division for Neuromodulation, Medical School, University of Cologne @2 Cologne @3 DEU @Z 1 aut.`
A14	`03`			`@1 Institute of Laboratory Animal Sciences, China Academy of Medical Sciences @2 Beijing @3 CHN @Z 2 aut. @Z 5 aut.`
A14	`04`			`@1 Motac Neuroscience @2 Manchester @3 GBR @Z 2 aut. @Z 5 aut.`
A14	`05`			`@1 Univ. de Bordeaux, Institut des Maladies Neurodégénératives, UMR 5293 @2 Bordeaux @3 FRA @Z 4 aut. @Z 5 aut. @Z 6 aut. @Z 7 aut.`
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A44				`@0 0000 @1 © 2013 INIST-CNRS. All rights reserved.`
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A60				`@1 P @3 CC`
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A64	`01`	`1`		`@0 Annals of neurology`
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C01	`01`		`ENG`	@0 Coordinated reset neuromodulation consists of the application of consecutive brief high-frequency pulse trains through the different contacts of the stimulation electrode. In theoretical studies, by achieving unlearning of abnormal connectivity between neurons, coordinated reset neuromodulation reduces pathological synchronization, a hallmark feature of Parkinson's disease pathophysiology. Here we show that coordinated reset neuromodulation of the subthalamic nucleus has both acute and sustained long-lasting aftereffects on motor function in parkinsonian nonhuman primates. Long-lasting aftereffects were not observed with classical deep brain stimulation. These observations encourage further development of coordinated reset neuromodulation for treating motor symptoms in Parkinson disease patients.
C02	`01`	`X`		`@0 002B17`
C02	`02`	`X`		`@0 002B02B06`
C03	`01`	`X`	`FRE`	`@0 Maladie de Parkinson @2 NM @5 01`
C03	`01`	`X`	`ENG`	`@0 Parkinson disease @2 NM @5 01`
C03	`01`	`X`	`SPA`	`@0 Parkinson enfermedad @2 NM @5 01`
C03	`02`	`X`	`FRE`	`@0 Pathologie du système nerveux @5 02`
C03	`02`	`X`	`ENG`	`@0 Nervous system diseases @5 02`
C03	`02`	`X`	`SPA`	`@0 Sistema nervioso patología @5 02`
C03	`03`	`X`	`FRE`	`@0 Animal @5 09`
C03	`03`	`X`	`ENG`	`@0 Animal @5 09`
C03	`03`	`X`	`SPA`	`@0 Animal @5 09`
C03	`04`	`X`	`FRE`	`@0 Singe @5 10`
C03	`04`	`X`	`ENG`	`@0 Monkey @5 10`
C03	`04`	`X`	`SPA`	`@0 Mono @5 10`
C07	`01`	`X`	`FRE`	`@0 Primates @2 NS`
C07	`01`	`X`	`ENG`	`@0 Primates @2 NS`
C07	`01`	`X`	`SPA`	`@0 Primates @2 NS`
C07	`02`	`X`	`FRE`	`@0 Mammalia @2 NS`
C07	`02`	`X`	`ENG`	`@0 Mammalia @2 NS`
C07	`02`	`X`	`SPA`	`@0 Mammalia @2 NS`
C07	`03`	`X`	`FRE`	`@0 Vertebrata @2 NS`
C07	`03`	`X`	`ENG`	`@0 Vertebrata @2 NS`
C07	`03`	`X`	`SPA`	`@0 Vertebrata @2 NS`
C07	`04`	`X`	`FRE`	`@0 Pathologie de l'encéphale @5 37`
C07	`04`	`X`	`ENG`	`@0 Cerebral disorder @5 37`
C07	`04`	`X`	`SPA`	`@0 Encéfalo patología @5 37`
C07	`05`	`X`	`FRE`	`@0 Syndrome extrapyramidal @5 38`
C07	`05`	`X`	`ENG`	`@0 Extrapyramidal syndrome @5 38`
C07	`05`	`X`	`SPA`	`@0 Extrapiramidal síndrome @5 38`
C07	`06`	`X`	`FRE`	`@0 Maladie dégénérative @5 39`
C07	`06`	`X`	`ENG`	`@0 Degenerative disease @5 39`
C07	`06`	`X`	`SPA`	`@0 Enfermedad degenerativa @5 39`
C07	`07`	`X`	`FRE`	`@0 Pathologie du système nerveux central @5 40`
C07	`07`	`X`	`ENG`	`@0 Central nervous system disease @5 40`
C07	`07`	`X`	`SPA`	`@0 Sistema nervosio central patología @5 40`
N21				`@1 042`
N44	`01`			`@1 OTO`
N82				`@1 OTO`

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Pascal:13-0070325

Le document en format XML

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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Coordinated Reset Has Sustained Aftereffects in Parkinsonian Monkeys</title>
<author><name sortKey="Tass, Peter A" sort="Tass, Peter A" uniqKey="Tass P" first="Peter A." last="Tass">Peter A. Tass</name>
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<author><name sortKey="Bezard, Erwan" sort="Bezard, Erwan" uniqKey="Bezard E" first="Erwan" last="Bezard">Erwan Bezard</name>
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<author><name sortKey="Boraud, Thomas" sort="Boraud, Thomas" uniqKey="Boraud T" first="Thomas" last="Boraud">Thomas Boraud</name>
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<author><name sortKey="Meissner, Wassilios G" sort="Meissner, Wassilios G" uniqKey="Meissner W" first="Wassilios G." last="Meissner">Wassilios G. Meissner</name>
<affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Univ. de Bordeaux, Institut des Maladies Neurodégénératives, UMR 5293</s1>
<s2>Bordeaux</s2>
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<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
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<country>France</country>
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<affiliation wicri:level="1"><inist:fA14 i1="06"><s1>CNRS, Institut des Maladies Neurodégénératives, UMR 5293</s1>
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<country>France</country>
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<affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Service de Neurologie, CHU de Bordeaux</s1>
<s2>Pessac</s2>
<s3>FRA</s3>
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<sZ>6 aut.</sZ>
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<country>France</country>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Centre de reference atrophie multisystématisée, CHU de Bordeaux</s1>
<s2>Pessac</s2>
<s3>FRA</s3>
<sZ>7 aut.</sZ>
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<country>France</country>
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<series><title level="j" type="main">Annals of neurology</title>
<title level="j" type="abbreviated">Ann. neurol.</title>
<idno type="ISSN">0364-5134</idno>
<imprint><date when="2012">2012</date>
</imprint>
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<seriesStmt><title level="j" type="main">Annals of neurology</title>
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<idno type="ISSN">0364-5134</idno>
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</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animal</term>
<term>Monkey</term>
<term>Nervous system diseases</term>
<term>Parkinson disease</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Maladie de Parkinson</term>
<term>Pathologie du   système nerveux</term>
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<term>Singe</term>
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<front><div type="abstract" xml:lang="en">Coordinated reset neuromodulation consists of the application of consecutive brief high-frequency pulse trains through the different contacts of the stimulation electrode. In theoretical studies, by achieving unlearning of abnormal connectivity between neurons, coordinated reset neuromodulation reduces pathological synchronization, a hallmark feature of Parkinson's disease pathophysiology. Here we show that coordinated reset neuromodulation of the subthalamic nucleus has both acute and sustained long-lasting aftereffects on motor function in parkinsonian nonhuman primates. Long-lasting aftereffects were not observed with classical deep brain stimulation. These observations encourage further development of coordinated reset neuromodulation for treating motor symptoms in Parkinson disease patients.</div>
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<fA08 i1="01" i2="1" l="ENG"><s1>Coordinated Reset Has Sustained Aftereffects in Parkinsonian Monkeys</s1>
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	La maladie de Parkinson en France (serveur d'exploration)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

La maladie de Parkinson en France (serveur d'exploration)

Coordinated Reset Has Sustained Aftereffects in Parkinsonian Monkeys

Coordinated Reset Has Sustained Aftereffects in Parkinsonian Monkeys

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