La maladie de Parkinson en France (serveur d'exploration)

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Adjustments of Conflict Monitoring in Parkinson's Disease

Identifieur interne : 000E25 ( PascalFrancis/Curation ); précédent : 000E24; suivant : 000E26

Adjustments of Conflict Monitoring in Parkinson's Disease

Auteurs : Camille A. Bonnin [France] ; Jean-Luc Houeto [France] ; Roger Gil [France] ; Cédric A. Bouquet [France]

Source :

RBID : Pascal:10-0384910

Descripteurs français

English descriptors

Abstract

Objective: In Stroop-like tasks, the detection of conflict triggers adjustments of cognitive control to reduce conflict in subsequent trials. The present study tested the hypothesis of an impaired modulation of conflict monitoring in Parkinson's disease (PD). Method: 18 PD patients and 18 healthy control (HC) participants performed a Stroop-like task in 2 conditions differing in term of incongruent/congruent stimuli ratio. Results: HC participants demonstrated a sustained modulation of interference effect, the interference effect being decreased when the proportion of incongruent stimuli was high. A trial-by-trial analysis also showed that in the HC group, processing an incongruent stimulus reduced interference in the subsequent trial. Unlike controls, PD patients did not demonstrate any transient or sustained reduction of the interference effect. Conclusion: Within the framework of recent models, these results can be interpreted as an impairment of a proactive mode of cognitive control in patients with PD.
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A11 02  1    @1 HOUETO (Jean-Luc)
A11 03  1    @1 GIL (Roger)
A11 04  1    @1 BOUQUET (Cédric A.)
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C01 01    ENG  @0 Objective: In Stroop-like tasks, the detection of conflict triggers adjustments of cognitive control to reduce conflict in subsequent trials. The present study tested the hypothesis of an impaired modulation of conflict monitoring in Parkinson's disease (PD). Method: 18 PD patients and 18 healthy control (HC) participants performed a Stroop-like task in 2 conditions differing in term of incongruent/congruent stimuli ratio. Results: HC participants demonstrated a sustained modulation of interference effect, the interference effect being decreased when the proportion of incongruent stimuli was high. A trial-by-trial analysis also showed that in the HC group, processing an incongruent stimulus reduced interference in the subsequent trial. Unlike controls, PD patients did not demonstrate any transient or sustained reduction of the interference effect. Conclusion: Within the framework of recent models, these results can be interpreted as an impairment of a proactive mode of cognitive control in patients with PD.
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N21       @1 249

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Pascal:10-0384910

Le document en format XML

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