La maladie de Parkinson en France (serveur d'exploration)

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Overactivation of primary motor cortex is asymmetrical in hemiparkinsonian patients

Identifieur interne : 000075 ( PascalFrancis/Curation ); précédent : 000074; suivant : 000076

Overactivation of primary motor cortex is asymmetrical in hemiparkinsonian patients

Auteurs : S. Thobois [France] ; P. Dominey [France] ; J. Decety [France] ; P. Pollak [France] ; M. C. Gregoire [France] ; E. Broussolle [France]

Source :

RBID : Pascal:00-0330470

Descripteurs français

English descriptors

Abstract

Regional cerebral blood flow (rCBF) was measured using PET and H215O in Parkinson's disease (PD) patients with predominantly right-sided akinetic-rigid symptoms and in control subjects during the execution of an externally cued motor task either with the left of the right hand. During the execution of the task with the left, non-akinctic, hand, cerebral activation in PD patients appeared similar to that of controls. Activated areas were the primary motor cortex, premotor cortex, parietal cortes and cerebellum. When the task was executed with the right, akinetic, hand cerebral activation in PD patients differed from that of controis subjects The most important change was a bilateral activation of the primary motor cortex. We conclude that overactivation at primary motor cortex is asymmeuical in hemiparkinsonian patients.
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A08 01  1  ENG  @1 Overactivation of primary motor cortex is asymmetrical in hemiparkinsonian patients
A11 01  1    @1 THOBOIS (S.)
A11 02  1    @1 DOMINEY (P.)
A11 03  1    @1 DECETY (J.)
A11 04  1    @1 POLLAK (P.)
A11 05  1    @1 GREGOIRE (M. C.)
A11 06  1    @1 BROUSSOLLE (E.)
A14 01      @1 Department of Neurology and CERMEP, Neurological Hospital Pierre Wertheimer, 59 Bd Pinel @2 69003 Lyon @3 FRA @Z 1 aut. @Z 6 aut.
A14 02      @1 Institute of Cognitive Science, CNRS @2 Lyon @3 FRA @Z 2 aut.
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A14 04      @1 Department of Neurology, CHU de Grenoble @2 Grenoble @3 FRA @Z 4 aut.
A14 05      @1 Service Hospitalier Frédéric Joliot @2 Orsay @3 FRA @Z 5 aut.
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C01 01    ENG  @0 Regional cerebral blood flow (rCBF) was measured using PET and H215O in Parkinson's disease (PD) patients with predominantly right-sided akinetic-rigid symptoms and in control subjects during the execution of an externally cued motor task either with the left of the right hand. During the execution of the task with the left, non-akinctic, hand, cerebral activation in PD patients appeared similar to that of controls. Activated areas were the primary motor cortex, premotor cortex, parietal cortes and cerebellum. When the task was executed with the right, akinetic, hand cerebral activation in PD patients differed from that of controis subjects The most important change was a bilateral activation of the primary motor cortex. We conclude that overactivation at primary motor cortex is asymmeuical in hemiparkinsonian patients.
C02 01  X    @0 002A26D04
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C03 01  X  ENG  @0 Motor cortex @5 01
C03 01  X  SPA  @0 Corteza motora @5 01
C03 02  X  FRE  @0 Parkinson maladie @5 02
C03 02  X  ENG  @0 Parkinson disease @5 02
C03 02  X  SPA  @0 Parkinson enfermedad @5 02
C03 03  X  FRE  @0 Débit sanguin @5 03
C03 03  X  ENG  @0 Blood flow @5 03
C03 03  X  SPA  @0 Flujo sanguíneo @5 03
C03 04  X  FRE  @0 Tomoscintigraphie @5 04
C03 04  X  ENG  @0 Emission tomography @5 04
C03 04  X  SPA  @0 Tomocentelleografía @5 04
C03 05  X  FRE  @0 Contrôle moteur @5 05
C03 05  X  ENG  @0 Motor control @5 05
C03 05  X  SPA  @0 Control motor @5 05
C03 06  X  FRE  @0 Akinésie @5 06
C03 06  X  ENG  @0 Akinesia @5 06
C03 06  X  SPA  @0 Aquinesia @5 06
C03 07  X  FRE  @0 Symétrie @5 07
C03 07  X  ENG  @0 Symmetry @5 07
C03 07  X  SPA  @0 Simetría @5 07
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C07 01  X  SPA  @0 Encéfalo @5 20
C07 02  X  FRE  @0 Maladie dégénérative @5 23
C07 02  X  ENG  @0 Degenerative disease @5 23
C07 02  X  SPA  @0 Enfermedad degenerativa @5 23
C07 03  X  FRE  @0 Méthode mesure @5 29
C07 03  X  ENG  @0 Measurement method @5 29
C07 03  X  SPA  @0 Método medida @5 29
C07 04  X  FRE  @0 Motricité @5 32
C07 04  X  ENG  @0 Motricity @5 32
C07 04  X  SPA  @0 Motricidad @5 32
N21       @1 228

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<s5>20</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE">
<s0>Maladie dégénérative</s0>
<s5>23</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG">
<s0>Degenerative disease</s0>
<s5>23</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA">
<s0>Enfermedad degenerativa</s0>
<s5>23</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE">
<s0>Méthode mesure</s0>
<s5>29</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG">
<s0>Measurement method</s0>
<s5>29</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA">
<s0>Método medida</s0>
<s5>29</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE">
<s0>Motricité</s0>
<s5>32</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG">
<s0>Motricity</s0>
<s5>32</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA">
<s0>Motricidad</s0>
<s5>32</s5>
</fC07>
<fN21>
<s1>228</s1>
</fN21>
</pA>
</standard>
</inist>
</record>

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