ParkinsonFranceV1, PascalFrancis, Corpus, bibRecord, 001541

Effects of the method of drawing regions of interest on the differential diagnosis of extrapyramidal syndromes using 123I-iodolisuride SPET

Identifieur interne : 001541 ( PascalFrancis/Corpus ); précédent : 001540; suivant : 001542

Effects of the method of drawing regions of interest on the differential diagnosis of extrapyramidal syndromes using 123I-iodolisuride SPET

Auteurs : J.-L. Baulieu ; M.-J. Ribeiro ; C. Levilion-Prunier ; F. Tranquart ; J.-R. Chartier ; D. Guilloteau ; J.-P. Cottier ; J.-C. Besnard ; L. Pourcelot ; A. Autret

Source :

Nuclear medicine communications [ 0143-3636 ] ; 1999.

RBID : Pascal:99-0094911

Descripteurs français

Pascal (Inist)
- Extrapyramidal syndrome, Homme, Iode, Tomoscintigraphie, Photon, Diagnostic différentiel, Récepteur dopaminergique D2, Anatomie, Localisation, Analyse quantitative.

English descriptors

KwdEn :
- Anatomy, D2 Dopamine receptor, Differential diagnostic, Emission tomography, Extrapyramidal syndrome, Human, Iodine, Localization, Photon, Quantitative analysis.

Abstract

Various parameters are currently used for the semi-quantitative assessment of dopamine D₂ receptors and differ according to the delineation of the striatal region of interest (ROI) and the choice of the reference ROI. The aim of this study was to assess the value of different ROI approaches in differentiating patients with normal or increased numbers of D₂ dopamine receptors (group 1 = Parkinson's disease, n = 8) from patients with decreased dopamine D2 receptors (group 2 = other extrapyramidal syndromes, n = 9) using ¹²³I-iodolisuride SPET (ILIS-SPET). ¹²³I-iodolisuride (190 ± 31 MBq) and ⁹⁹Tc^m-ethyl cysteinate dimer (⁹⁹Tc^m-ECD) perfusion SPET were performed in the the same position, with a dual-headed gamera camera equipped with fan beam collimators. Both a geometric approach (ellipse, circle or rectangle) and an anatomical approach using the CT scan and perfusion SPET as anatomical guides were used to draw striatal and reference ROIs. A total of 33 different parameters were calculated for each patient, indicating the ratio of counts between the striatal and reference ROIs (frontal, occipital cortex or cerebellum) and the asymmetry between the right and left striatum. More significant differences between group 1 and group 2 were found by using geometric ROIs than by using anatomical ROIs. The most discriminant ratios were the caudate/occipital, caudate/frontal and striatum/occipital ratios (P = 0.001, P = 0.002, P = 0.003 respectively). A close correlation was found between the striatum/caudate and striatum/occipital ratios, but not between the striatum/frontal and striatum/occipital ratios or between the striatum/frontal and striatum/caudate ratios. We conclude that the occipital cortex is the best reference for the semi-quantitative evaluation of dopamine D₂ receptors as the frontal cortex could include some dopamine D₂ receptor-bound radioligand, and that the caudate/occipital ratio is an appropriate parameter for differentiating Parkinson's disease from non-Parkinson extrapyramidal syndrome by 1-iodolisuride SPET.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

A01	`01`	`1`		`@0 0143-3636`
A03		`1`		`@0 Nucl. med. common.`
A05				`@2 20`
A06				`@2 1`
A08	`01`	`1`	`ENG`	`@1 Effects of the method of drawing regions of interest on the differential diagnosis of extrapyramidal syndromes using ¹²³I-iodolisuride SPET`
A11	`01`	`1`		`@1 BAULIEU (J.-L.)`
A11	`02`	`1`		`@1 RIBEIRO (M.-J.)`
A11	`03`	`1`		`@1 LEVILION-PRUNIER (C.)`
A11	`04`	`1`		`@1 TRANQUART (F.)`
A11	`05`	`1`		`@1 CHARTIER (J.-R.)`
A11	`06`	`1`		`@1 GUILLOTEAU (D.)`
A11	`07`	`1`		`@1 COTTIER (J.-P.)`
A11	`08`	`1`		`@1 BESNARD (J.-C.)`
A11	`09`	`1`		`@1 POURCELOT (L.)`
A11	`10`	`1`		`@1 AUTRET (A.)`
A14	`01`			`@1 Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours @3 FRA @Z 1 aut. @Z 3 aut. @Z 4 aut. @Z 5 aut. @Z 6 aut. @Z 7 aut. @Z 8 aut. @Z 9 aut. @Z 10 aut.`
A14	`02`			`@1 Servico de Biofisica, IBILI @2 Coimbra @3 PRT @Z 2 aut.`
A20				`@1 77-84`
A21				`@1 1999`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 21691 @5 354000073616380100`
A44				`@0 0000 @1 © 1999 INIST-CNRS. All rights reserved.`
A45				`@0 19 ref.`
A47	`01`	`1`		`@0 99-0094911`
A60				`@1 P`
A61				`@0 A`
A64		`1`		`@0 Nuclear medicine communications`
A66	`01`			`@0 GBR`
C01	`01`		`ENG`	@0 Various parameters are currently used for the semi-quantitative assessment of dopamine D₂ receptors and differ according to the delineation of the striatal region of interest (ROI) and the choice of the reference ROI. The aim of this study was to assess the value of different ROI approaches in differentiating patients with normal or increased numbers of D₂ dopamine receptors (group 1 = Parkinson's disease, n = 8) from patients with decreased dopamine D2 receptors (group 2 = other extrapyramidal syndromes, n = 9) using ¹²³I-iodolisuride SPET (ILIS-SPET). ¹²³I-iodolisuride (190 ± 31 MBq) and ⁹⁹Tc^m-ethyl cysteinate dimer (⁹⁹Tc^m-ECD) perfusion SPET were performed in the the same position, with a dual-headed gamera camera equipped with fan beam collimators. Both a geometric approach (ellipse, circle or rectangle) and an anatomical approach using the CT scan and perfusion SPET as anatomical guides were used to draw striatal and reference ROIs. A total of 33 different parameters were calculated for each patient, indicating the ratio of counts between the striatal and reference ROIs (frontal, occipital cortex or cerebellum) and the asymmetry between the right and left striatum. More significant differences between group 1 and group 2 were found by using geometric ROIs than by using anatomical ROIs. The most discriminant ratios were the caudate/occipital, caudate/frontal and striatum/occipital ratios (P = 0.001, P = 0.002, P = 0.003 respectively). A close correlation was found between the striatum/caudate and striatum/occipital ratios, but not between the striatum/frontal and striatum/occipital ratios or between the striatum/frontal and striatum/caudate ratios. We conclude that the occipital cortex is the best reference for the semi-quantitative evaluation of dopamine D₂ receptors as the frontal cortex could include some dopamine D₂ receptor-bound radioligand, and that the caudate/occipital ratio is an appropriate parameter for differentiating Parkinson's disease from non-Parkinson extrapyramidal syndrome by 1-iodolisuride SPET.
C02	`01`	`X`		`@0 002B17I`
C03	`01`	`X`	`FRE`	`@0 Extrapyramidal syndrome @5 01`
C03	`01`	`X`	`ENG`	`@0 Extrapyramidal syndrome @5 01`
C03	`01`	`X`	`SPA`	`@0 Extrapiramidal síndrome @5 01`
C03	`02`	`X`	`FRE`	`@0 Homme @5 02`
C03	`02`	`X`	`ENG`	`@0 Human @5 02`
C03	`02`	`X`	`SPA`	`@0 Hombre @5 02`
C03	`03`	`X`	`FRE`	`@0 Iode @2 NC @5 03`
C03	`03`	`X`	`ENG`	`@0 Iodine @2 NC @5 03`
C03	`03`	`X`	`GER`	`@0 Iod @2 NC @5 03`
C03	`03`	`X`	`SPA`	`@0 Iodo @2 NC @5 03`
C03	`04`	`X`	`FRE`	`@0 Tomoscintigraphie @5 04`
C03	`04`	`X`	`ENG`	`@0 Emission tomography @5 04`
C03	`04`	`X`	`SPA`	`@0 Tomocentelleografía @5 04`
C03	`05`	`X`	`FRE`	`@0 Photon @5 05`
C03	`05`	`X`	`ENG`	`@0 Photon @5 05`
C03	`05`	`X`	`GER`	`@0 Photon @5 05`
C03	`05`	`X`	`SPA`	`@0 Fotón @5 05`
C03	`06`	`X`	`FRE`	`@0 Diagnostic différentiel @5 06`
C03	`06`	`X`	`ENG`	`@0 Differential diagnostic @5 06`
C03	`06`	`X`	`SPA`	`@0 Diagnóstico diferencial @5 06`
C03	`07`	`X`	`FRE`	`@0 Récepteur dopaminergique D2 @5 07`
C03	`07`	`X`	`ENG`	`@0 D2 Dopamine receptor @5 07 @6 «D2» Dopamine receptor`
C03	`07`	`X`	`SPA`	`@0 Receptor dopaminérgico D2 @5 07`
C03	`08`	`X`	`FRE`	`@0 Anatomie @5 08`
C03	`08`	`X`	`ENG`	`@0 Anatomy @5 08`
C03	`08`	`X`	`SPA`	`@0 Anatomía @5 08`
C03	`09`	`X`	`FRE`	`@0 Localisation @5 09`
C03	`09`	`X`	`ENG`	`@0 Localization @5 09`
C03	`09`	`X`	`SPA`	`@0 Localización @5 09`
C03	`10`	`X`	`FRE`	`@0 Analyse quantitative @5 10`
C03	`10`	`X`	`ENG`	`@0 Quantitative analysis @5 10`
C03	`10`	`X`	`GER`	`@0 Quantitative Analyse @5 10`
C03	`10`	`X`	`SPA`	`@0 Análisis cuantitativo @5 10`
C07	`01`	`X`	`FRE`	`@0 Système nerveux pathologie @5 37`
C07	`01`	`X`	`ENG`	`@0 Nervous system diseases @5 37`
C07	`01`	`X`	`SPA`	`@0 Sistema nervioso patología @5 37`
C07	`02`	`X`	`FRE`	`@0 Système nerveux central pathologie @5 38`
C07	`02`	`X`	`ENG`	`@0 Central nervous system disease @5 38`
C07	`02`	`X`	`SPA`	`@0 Sistema nervosio central patología @5 38`
C07	`03`	`X`	`FRE`	`@0 Encéphale pathologie @5 39`
C07	`03`	`X`	`ENG`	`@0 Cerebral disorder @5 39`
C07	`03`	`X`	`SPA`	`@0 Encéfalo patología @5 39`
C07	`04`	`X`	`FRE`	`@0 Exploration radioisotopique @5 45`
C07	`04`	`X`	`ENG`	`@0 Radionuclide study @5 45`
C07	`04`	`X`	`SPA`	`@0 Exploración radioisotópica @5 45`
N21				`@1 053`

Format Inist (serveur)

NO :	PASCAL 99-0094911 INIST
ET :	Effects of the method of drawing regions of interest on the differential diagnosis of extrapyramidal syndromes using ¹²³I-iodolisuride SPET
AU :	BAULIEU (J.-L.); RIBEIRO (M.-J.); LEVILION-PRUNIER (C.); TRANQUART (F.); CHARTIER (J.-R.); GUILLOTEAU (D.); COTTIER (J.-P.); BESNARD (J.-C.); POURCELOT (L.); AUTRET (A.)
AF :	Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours/France (1 aut., 3 aut., 4 aut., 5 aut., 6 aut., 7 aut., 8 aut., 9 aut., 10 aut.); Servico de Biofisica, IBILI/Coimbra/Portugal (2 aut.)
DT :	Publication en série; Niveau analytique
SO :	Nuclear medicine communications; ISSN 0143-3636; Royaume-Uni; Da. 1999; Vol. 20; No. 1; Pp. 77-84; Bibl. 19 ref.
LA :	Anglais
EA :	Various parameters are currently used for the semi-quantitative assessment of dopamine D₂ receptors and differ according to the delineation of the striatal region of interest (ROI) and the choice of the reference ROI. The aim of this study was to assess the value of different ROI approaches in differentiating patients with normal or increased numbers of D₂ dopamine receptors (group 1 = Parkinson's disease, n = 8) from patients with decreased dopamine D2 receptors (group 2 = other extrapyramidal syndromes, n = 9) using ¹²³I-iodolisuride SPET (ILIS-SPET). ¹²³I-iodolisuride (190 ± 31 MBq) and ⁹⁹Tc^m-ethyl cysteinate dimer (⁹⁹Tc^m-ECD) perfusion SPET were performed in the the same position, with a dual-headed gamera camera equipped with fan beam collimators. Both a geometric approach (ellipse, circle or rectangle) and an anatomical approach using the CT scan and perfusion SPET as anatomical guides were used to draw striatal and reference ROIs. A total of 33 different parameters were calculated for each patient, indicating the ratio of counts between the striatal and reference ROIs (frontal, occipital cortex or cerebellum) and the asymmetry between the right and left striatum. More significant differences between group 1 and group 2 were found by using geometric ROIs than by using anatomical ROIs. The most discriminant ratios were the caudate/occipital, caudate/frontal and striatum/occipital ratios (P = 0.001, P = 0.002, P = 0.003 respectively). A close correlation was found between the striatum/caudate and striatum/occipital ratios, but not between the striatum/frontal and striatum/occipital ratios or between the striatum/frontal and striatum/caudate ratios. We conclude that the occipital cortex is the best reference for the semi-quantitative evaluation of dopamine D₂ receptors as the frontal cortex could include some dopamine D₂ receptor-bound radioligand, and that the caudate/occipital ratio is an appropriate parameter for differentiating Parkinson's disease from non-Parkinson extrapyramidal syndrome by 1-iodolisuride SPET.
CC :	002B17I
FD :	Extrapyramidal syndrome; Homme; Iode; Tomoscintigraphie; Photon; Diagnostic différentiel; Récepteur dopaminergique D2; Anatomie; Localisation; Analyse quantitative
FG :	Système nerveux pathologie; Système nerveux central pathologie; Encéphale pathologie; Exploration radioisotopique
ED :	Extrapyramidal syndrome; Human; Iodine; Emission tomography; Photon; Differential diagnostic; D2 Dopamine receptor; Anatomy; Localization; Quantitative analysis
EG :	Nervous system diseases; Central nervous system disease; Cerebral disorder; Radionuclide study
GD :	Iod; Photon; Quantitative Analyse
SD :	Extrapiramidal síndrome; Hombre; Iodo; Tomocentelleografía; Fotón; Diagnóstico diferencial; Receptor dopaminérgico D2; Anatomía; Localización; Análisis cuantitativo
LO :	INIST-21691.354000073616380100
ID :	99-0094911

Links to Exploration step

Pascal:99-0094911

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Effects of the method of drawing regions of interest on the differential diagnosis of extrapyramidal syndromes using <sup>123</sup>
I-iodolisuride SPET</title>
<author><name sortKey="Baulieu, J L" sort="Baulieu, J L" uniqKey="Baulieu J" first="J.-L." last="Baulieu">J.-L. Baulieu</name>
<affiliation><inist:fA14 i1="01"><s1>Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Ribeiro, M J" sort="Ribeiro, M J" uniqKey="Ribeiro M" first="M.-J." last="Ribeiro">M.-J. Ribeiro</name>
<affiliation><inist:fA14 i1="02"><s1>Servico de Biofisica, IBILI</s1>
<s2>Coimbra</s2>
<s3>PRT</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Levilion Prunier, C" sort="Levilion Prunier, C" uniqKey="Levilion Prunier C" first="C." last="Levilion-Prunier">C. Levilion-Prunier</name>
<affiliation><inist:fA14 i1="01"><s1>Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Tranquart, F" sort="Tranquart, F" uniqKey="Tranquart F" first="F." last="Tranquart">F. Tranquart</name>
<affiliation><inist:fA14 i1="01"><s1>Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Chartier, J R" sort="Chartier, J R" uniqKey="Chartier J" first="J.-R." last="Chartier">J.-R. Chartier</name>
<affiliation><inist:fA14 i1="01"><s1>Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Guilloteau, D" sort="Guilloteau, D" uniqKey="Guilloteau D" first="D." last="Guilloteau">D. Guilloteau</name>
<affiliation><inist:fA14 i1="01"><s1>Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Cottier, J P" sort="Cottier, J P" uniqKey="Cottier J" first="J.-P." last="Cottier">J.-P. Cottier</name>
<affiliation><inist:fA14 i1="01"><s1>Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Besnard, J C" sort="Besnard, J C" uniqKey="Besnard J" first="J.-C." last="Besnard">J.-C. Besnard</name>
<affiliation><inist:fA14 i1="01"><s1>Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Pourcelot, L" sort="Pourcelot, L" uniqKey="Pourcelot L" first="L." last="Pourcelot">L. Pourcelot</name>
<affiliation><inist:fA14 i1="01"><s1>Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Autret, A" sort="Autret, A" uniqKey="Autret A" first="A." last="Autret">A. Autret</name>
<affiliation><inist:fA14 i1="01"><s1>Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">99-0094911</idno>
<date when="1999">1999</date>
<idno type="stanalyst">PASCAL 99-0094911 INIST</idno>
<idno type="RBID">Pascal:99-0094911</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">001541</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Effects of the method of drawing regions of interest on the differential diagnosis of extrapyramidal syndromes using <sup>123</sup>
I-iodolisuride SPET</title>
<author><name sortKey="Baulieu, J L" sort="Baulieu, J L" uniqKey="Baulieu J" first="J.-L." last="Baulieu">J.-L. Baulieu</name>
<affiliation><inist:fA14 i1="01"><s1>Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Ribeiro, M J" sort="Ribeiro, M J" uniqKey="Ribeiro M" first="M.-J." last="Ribeiro">M.-J. Ribeiro</name>
<affiliation><inist:fA14 i1="02"><s1>Servico de Biofisica, IBILI</s1>
<s2>Coimbra</s2>
<s3>PRT</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Levilion Prunier, C" sort="Levilion Prunier, C" uniqKey="Levilion Prunier C" first="C." last="Levilion-Prunier">C. Levilion-Prunier</name>
<affiliation><inist:fA14 i1="01"><s1>Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Tranquart, F" sort="Tranquart, F" uniqKey="Tranquart F" first="F." last="Tranquart">F. Tranquart</name>
<affiliation><inist:fA14 i1="01"><s1>Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Chartier, J R" sort="Chartier, J R" uniqKey="Chartier J" first="J.-R." last="Chartier">J.-R. Chartier</name>
<affiliation><inist:fA14 i1="01"><s1>Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Guilloteau, D" sort="Guilloteau, D" uniqKey="Guilloteau D" first="D." last="Guilloteau">D. Guilloteau</name>
<affiliation><inist:fA14 i1="01"><s1>Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Cottier, J P" sort="Cottier, J P" uniqKey="Cottier J" first="J.-P." last="Cottier">J.-P. Cottier</name>
<affiliation><inist:fA14 i1="01"><s1>Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Besnard, J C" sort="Besnard, J C" uniqKey="Besnard J" first="J.-C." last="Besnard">J.-C. Besnard</name>
<affiliation><inist:fA14 i1="01"><s1>Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Pourcelot, L" sort="Pourcelot, L" uniqKey="Pourcelot L" first="L." last="Pourcelot">L. Pourcelot</name>
<affiliation><inist:fA14 i1="01"><s1>Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
<author><name sortKey="Autret, A" sort="Autret, A" uniqKey="Autret A" first="A." last="Autret">A. Autret</name>
<affiliation><inist:fA14 i1="01"><s1>Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</inist:fA14>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Nuclear medicine communications</title>
<title level="j" type="abbreviated">Nucl. med. common.</title>
<idno type="ISSN">0143-3636</idno>
<imprint><date when="1999">1999</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Nuclear medicine communications</title>
<title level="j" type="abbreviated">Nucl. med. common.</title>
<idno type="ISSN">0143-3636</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anatomy</term>
<term>D2 Dopamine receptor</term>
<term>Differential diagnostic</term>
<term>Emission tomography</term>
<term>Extrapyramidal syndrome</term>
<term>Human</term>
<term>Iodine</term>
<term>Localization</term>
<term>Photon</term>
<term>Quantitative analysis</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Extrapyramidal syndrome</term>
<term>Homme</term>
<term>Iode</term>
<term>Tomoscintigraphie</term>
<term>Photon</term>
<term>Diagnostic différentiel</term>
<term>Récepteur dopaminergique D2</term>
<term>Anatomie</term>
<term>Localisation</term>
<term>Analyse quantitative</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Various parameters are currently used for the semi-quantitative assessment of dopamine D<sub>2</sub>
 receptors and differ according to the delineation of the striatal region of interest (ROI) and the choice of the reference ROI. The aim of this study was to assess the value of different ROI approaches in differentiating patients with normal or increased numbers of D<sub>2</sub>
 dopamine receptors (group 1 = Parkinson's disease, n = 8) from patients with decreased dopamine D2 receptors (group 2 = other extrapyramidal syndromes, n = 9) using <sup>123</sup>
I-iodolisuride SPET (ILIS-SPET). <sup>123</sup>
I-iodolisuride (190 ± 31 MBq) and <sup>99</sup>
Tc<sup>m</sup>
-ethyl cysteinate dimer (<sup>99</sup>
Tc<sup>m</sup>
-ECD) perfusion SPET were performed in the the same position, with a dual-headed gamera camera equipped with fan beam collimators. Both a geometric approach (ellipse, circle or rectangle) and an anatomical approach using the CT scan and perfusion SPET as anatomical guides were used to draw striatal and reference ROIs. A total of 33 different parameters were calculated for each patient, indicating the ratio of counts between the striatal and reference ROIs (frontal, occipital cortex or cerebellum) and the asymmetry between the right and left striatum. More significant differences between group 1 and group 2 were found by using geometric ROIs than by using anatomical ROIs. The most discriminant ratios were the caudate/occipital, caudate/frontal and striatum/occipital ratios (P = 0.001, P = 0.002, P = 0.003 respectively). A close correlation was found between the striatum/caudate and striatum/occipital ratios, but not between the striatum/frontal and striatum/occipital ratios or between the striatum/frontal and striatum/caudate ratios. We conclude that the occipital cortex is the best reference for the semi-quantitative evaluation of dopamine D<sub>2</sub>
 receptors as the frontal cortex could include some dopamine D<sub>2</sub>
 receptor-bound radioligand, and that the caudate/occipital ratio is an appropriate parameter for differentiating Parkinson's disease from non-Parkinson extrapyramidal syndrome by 1-iodolisuride SPET.</div>
</front>
</TEI>
<inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0143-3636</s0>
</fA01>
<fA03 i2="1"><s0>Nucl. med. common.</s0>
</fA03>
<fA05><s2>20</s2>
</fA05>
<fA06><s2>1</s2>
</fA06>
<fA08 i1="01" i2="1" l="ENG"><s1>Effects of the method of drawing regions of interest on the differential diagnosis of extrapyramidal syndromes using <sup>123</sup>
I-iodolisuride SPET</s1>
</fA08>
<fA11 i1="01" i2="1"><s1>BAULIEU (J.-L.)</s1>
</fA11>
<fA11 i1="02" i2="1"><s1>RIBEIRO (M.-J.)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>LEVILION-PRUNIER (C.)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>TRANQUART (F.)</s1>
</fA11>
<fA11 i1="05" i2="1"><s1>CHARTIER (J.-R.)</s1>
</fA11>
<fA11 i1="06" i2="1"><s1>GUILLOTEAU (D.)</s1>
</fA11>
<fA11 i1="07" i2="1"><s1>COTTIER (J.-P.)</s1>
</fA11>
<fA11 i1="08" i2="1"><s1>BESNARD (J.-C.)</s1>
</fA11>
<fA11 i1="09" i2="1"><s1>POURCELOT (L.)</s1>
</fA11>
<fA11 i1="10" i2="1"><s1>AUTRET (A.)</s1>
</fA11>
<fA14 i1="01"><s1>Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours</s1>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
<sZ>8 aut.</sZ>
<sZ>9 aut.</sZ>
<sZ>10 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>Servico de Biofisica, IBILI</s1>
<s2>Coimbra</s2>
<s3>PRT</s3>
<sZ>2 aut.</sZ>
</fA14>
<fA20><s1>77-84</s1>
</fA20>
<fA21><s1>1999</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
<fA43 i1="01"><s1>INIST</s1>
<s2>21691</s2>
<s5>354000073616380100</s5>
</fA43>
<fA44><s0>0000</s0>
<s1>© 1999 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45><s0>19 ref.</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>99-0094911</s0>
</fA47>
<fA60><s1>P</s1>
</fA60>
<fA61><s0>A</s0>
</fA61>
<fA64 i2="1"><s0>Nuclear medicine communications</s0>
</fA64>
<fA66 i1="01"><s0>GBR</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>Various parameters are currently used for the semi-quantitative assessment of dopamine D<sub>2</sub>
 receptors and differ according to the delineation of the striatal region of interest (ROI) and the choice of the reference ROI. The aim of this study was to assess the value of different ROI approaches in differentiating patients with normal or increased numbers of D<sub>2</sub>
 dopamine receptors (group 1 = Parkinson's disease, n = 8) from patients with decreased dopamine D2 receptors (group 2 = other extrapyramidal syndromes, n = 9) using <sup>123</sup>
I-iodolisuride SPET (ILIS-SPET). <sup>123</sup>
I-iodolisuride (190 ± 31 MBq) and <sup>99</sup>
Tc<sup>m</sup>
-ethyl cysteinate dimer (<sup>99</sup>
Tc<sup>m</sup>
-ECD) perfusion SPET were performed in the the same position, with a dual-headed gamera camera equipped with fan beam collimators. Both a geometric approach (ellipse, circle or rectangle) and an anatomical approach using the CT scan and perfusion SPET as anatomical guides were used to draw striatal and reference ROIs. A total of 33 different parameters were calculated for each patient, indicating the ratio of counts between the striatal and reference ROIs (frontal, occipital cortex or cerebellum) and the asymmetry between the right and left striatum. More significant differences between group 1 and group 2 were found by using geometric ROIs than by using anatomical ROIs. The most discriminant ratios were the caudate/occipital, caudate/frontal and striatum/occipital ratios (P = 0.001, P = 0.002, P = 0.003 respectively). A close correlation was found between the striatum/caudate and striatum/occipital ratios, but not between the striatum/frontal and striatum/occipital ratios or between the striatum/frontal and striatum/caudate ratios. We conclude that the occipital cortex is the best reference for the semi-quantitative evaluation of dopamine D<sub>2</sub>
 receptors as the frontal cortex could include some dopamine D<sub>2</sub>
 receptor-bound radioligand, and that the caudate/occipital ratio is an appropriate parameter for differentiating Parkinson's disease from non-Parkinson extrapyramidal syndrome by 1-iodolisuride SPET.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B17I</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Extrapyramidal syndrome</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Extrapyramidal syndrome</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Extrapiramidal síndrome</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Homme</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Human</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Hombre</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Iode</s0>
<s2>NC</s2>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Iodine</s0>
<s2>NC</s2>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="GER"><s0>Iod</s0>
<s2>NC</s2>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Iodo</s0>
<s2>NC</s2>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Tomoscintigraphie</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Emission tomography</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Tomocentelleografía</s0>
<s5>04</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Photon</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Photon</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="GER"><s0>Photon</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Fotón</s0>
<s5>05</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Diagnostic différentiel</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Differential diagnostic</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Diagnóstico diferencial</s0>
<s5>06</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Récepteur dopaminergique D2</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>D2 Dopamine receptor</s0>
<s5>07</s5>
<s6>«D2» Dopamine receptor</s6>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Receptor dopaminérgico D2</s0>
<s5>07</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Anatomie</s0>
<s5>08</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Anatomy</s0>
<s5>08</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Anatomía</s0>
<s5>08</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Localisation</s0>
<s5>09</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Localization</s0>
<s5>09</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Localización</s0>
<s5>09</s5>
</fC03>
<fC03 i1="10" i2="X" l="FRE"><s0>Analyse quantitative</s0>
<s5>10</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG"><s0>Quantitative analysis</s0>
<s5>10</s5>
</fC03>
<fC03 i1="10" i2="X" l="GER"><s0>Quantitative Analyse</s0>
<s5>10</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Análisis cuantitativo</s0>
<s5>10</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Système nerveux pathologie</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Nervous system diseases</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Sistema nervioso patología</s0>
<s5>37</s5>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Système nerveux central pathologie</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Central nervous system disease</s0>
<s5>38</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Sistema nervosio central patología</s0>
<s5>38</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Encéphale pathologie</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Cerebral disorder</s0>
<s5>39</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Encéfalo patología</s0>
<s5>39</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Exploration radioisotopique</s0>
<s5>45</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Radionuclide study</s0>
<s5>45</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Exploración radioisotópica</s0>
<s5>45</s5>
</fC07>
<fN21><s1>053</s1>
</fN21>
</pA>
</standard>
<server><NO>PASCAL 99-0094911 INIST</NO>
<ET>Effects of the method of drawing regions of interest on the differential diagnosis of extrapyramidal syndromes using <sup>123</sup>
I-iodolisuride SPET</ET>
<AU>BAULIEU (J.-L.); RIBEIRO (M.-J.); LEVILION-PRUNIER (C.); TRANQUART (F.); CHARTIER (J.-R.); GUILLOTEAU (D.); COTTIER (J.-P.); BESNARD (J.-C.); POURCELOT (L.); AUTRET (A.)</AU>
<AF>Departments of Nuclear Medicine, Neurology and Neuroradiology, INSERM U316, CHU Tours/France (1 aut., 3 aut., 4 aut., 5 aut., 6 aut., 7 aut., 8 aut., 9 aut., 10 aut.); Servico de Biofisica, IBILI/Coimbra/Portugal (2 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Nuclear medicine communications; ISSN 0143-3636; Royaume-Uni; Da. 1999; Vol. 20; No. 1; Pp. 77-84; Bibl. 19 ref.</SO>
<LA>Anglais</LA>
<EA>Various parameters are currently used for the semi-quantitative assessment of dopamine D<sub>2</sub>
 receptors and differ according to the delineation of the striatal region of interest (ROI) and the choice of the reference ROI. The aim of this study was to assess the value of different ROI approaches in differentiating patients with normal or increased numbers of D<sub>2</sub>
 dopamine receptors (group 1 = Parkinson's disease, n = 8) from patients with decreased dopamine D2 receptors (group 2 = other extrapyramidal syndromes, n = 9) using <sup>123</sup>
I-iodolisuride SPET (ILIS-SPET). <sup>123</sup>
I-iodolisuride (190 ± 31 MBq) and <sup>99</sup>
Tc<sup>m</sup>
-ethyl cysteinate dimer (<sup>99</sup>
Tc<sup>m</sup>
-ECD) perfusion SPET were performed in the the same position, with a dual-headed gamera camera equipped with fan beam collimators. Both a geometric approach (ellipse, circle or rectangle) and an anatomical approach using the CT scan and perfusion SPET as anatomical guides were used to draw striatal and reference ROIs. A total of 33 different parameters were calculated for each patient, indicating the ratio of counts between the striatal and reference ROIs (frontal, occipital cortex or cerebellum) and the asymmetry between the right and left striatum. More significant differences between group 1 and group 2 were found by using geometric ROIs than by using anatomical ROIs. The most discriminant ratios were the caudate/occipital, caudate/frontal and striatum/occipital ratios (P = 0.001, P = 0.002, P = 0.003 respectively). A close correlation was found between the striatum/caudate and striatum/occipital ratios, but not between the striatum/frontal and striatum/occipital ratios or between the striatum/frontal and striatum/caudate ratios. We conclude that the occipital cortex is the best reference for the semi-quantitative evaluation of dopamine D<sub>2</sub>
 receptors as the frontal cortex could include some dopamine D<sub>2</sub>
 receptor-bound radioligand, and that the caudate/occipital ratio is an appropriate parameter for differentiating Parkinson's disease from non-Parkinson extrapyramidal syndrome by 1-iodolisuride SPET.</EA>
<CC>002B17I</CC>
<FD>Extrapyramidal syndrome; Homme; Iode; Tomoscintigraphie; Photon; Diagnostic différentiel; Récepteur dopaminergique D2; Anatomie; Localisation; Analyse quantitative</FD>
<FG>Système nerveux pathologie; Système nerveux central pathologie; Encéphale pathologie; Exploration radioisotopique</FG>
<ED>Extrapyramidal syndrome; Human; Iodine; Emission tomography; Photon; Differential diagnostic; D2 Dopamine receptor; Anatomy; Localization; Quantitative analysis</ED>
<EG>Nervous system diseases; Central nervous system disease; Cerebral disorder; Radionuclide study</EG>
<GD>Iod; Photon; Quantitative Analyse</GD>
<SD>Extrapiramidal síndrome; Hombre; Iodo; Tomocentelleografía; Fotón; Diagnóstico diferencial; Receptor dopaminérgico D2; Anatomía; Localización; Análisis cuantitativo</SD>
<LO>INIST-21691.354000073616380100</LO>
<ID>99-0094911</ID>
</server>
</inist>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/PascalFrancis/Corpus

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001541 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/PascalFrancis/Corpus/biblio.hfd -nk 001541 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    ParkinsonFranceV1
   |flux=    PascalFrancis
   |étape=   Corpus
   |type=    RBID
   |clé=     Pascal:99-0094911
   |texte=   Effects of the method of drawing regions of interest on the differential diagnosis of extrapyramidal syndromes using 123I-iodolisuride SPET
}}

This area was generated with Dilib version V0.6.29.
Data generation: Wed May 17 19:46:39 2017. Site generation: Mon Mar 4 15:48:15 2024

	La maladie de Parkinson en France (serveur d'exploration)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

La maladie de Parkinson en France (serveur d'exploration)

Effects of the method of drawing regions of interest on the differential diagnosis of extrapyramidal syndromes using 123I-iodolisuride SPET

Effects of the method of drawing regions of interest on the differential diagnosis of extrapyramidal syndromes using 123I-iodolisuride SPET

Source :

Descripteurs français

English descriptors

Abstract

Notice en format standard (ISO 2709)

Format Inist (serveur)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri