ParkinsonFranceV1, PascalFrancis, Corpus, bibRecord, 001225

Bullous pemphigoid in a leg affected with hemiparesia : a possible relation of neurological diseases with bullous pemphigoid?

Identifieur interne : 001225 ( PascalFrancis/Corpus ); précédent : 001224; suivant : 001226

Bullous pemphigoid in a leg affected with hemiparesia : a possible relation of neurological diseases with bullous pemphigoid?

Auteurs : Nicolas Foureur ; Vincent Descamps ; Bénédicte Lebrun-Vignes ; Catherine Picard-Dahan ; Maggy Grossin ; Stéphane Belaich ; Béatrice Crickx

Source :

EJD. European journal of dermatology [ 1167-1122 ] ; 2001.

RBID : Pascal:01-0310975

Descripteurs français

Pascal (Inist)
- Pemphigoïde bulleuse, Jambe, Association, Hémiplégie, Etude cas, Personne âgée.

English descriptors

KwdEn :
- Association, Bullous pemphigoid, Case study, Elderly, Hemiplegia, Leg.

Abstract

We report a typical case of bullous pemphigoid (BP) associated with a neurological disorder and study a possible link between neurological disorders and BP. An 84-year-old hemiplegic woman presented with unilateral BP on the hemiparetic side. BP was confirmed by histological and immunofluorescence data. The medical records of the previous 46 consecutive patients with BP were retrospectively analyzed (average age: 79; median age: 85). Thirty of the 46 patients with BP had neurological disorders. These disorders included dementia, epilepsy, multiple sclerosis, cerebral stroke, Parkinson's disease, gonadotropic adenoma, trembling, dyskinesia, lumbar spinal stenosis. In a control group of the 46 consecutive oldest patients (older than 71; average age: 82,5; median age: 80) with another skin disease referred during the previous two-year-period to our one-day-unit only, 13 patients had a neurological disorder. This study demonstrates that there is a high prevalence of neurological disorders in patients with BP (p = 0.0004). A prospective case control study with neurological examination and psychometrical evaluation is warranted to confirm these data. We speculate that neuroautoimmunity associated with the aging process or neurological disorders may be involved in pemphigoid development via an autoimmune response against dystonin which shares homology with bullous pemphigoid antigen 1. Bullous pemphigoid could be considered to be a marker of neurological disorder.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

A01	`01`	`1`		`@0 1167-1122`
A03		`1`		`@0 EJD, Eur. j. dermatol.`
A05				`@2 11`
A06				`@2 3`
A08	`01`	`1`	`ENG`	`@1 Bullous pemphigoid in a leg affected with hemiparesia : a possible relation of neurological diseases with bullous pemphigoid?`
A11	`01`	`1`		`@1 FOUREUR (Nicolas)`
A11	`02`	`1`		`@1 DESCAMPS (Vincent)`
A11	`03`	`1`		`@1 LEBRUN-VIGNES (Bénédicte)`
A11	`04`	`1`		`@1 PICARD-DAHAN (Catherine)`
A11	`05`	`1`		`@1 GROSSIN (Maggy)`
A11	`06`	`1`		`@1 BELAICH (Stéphane)`
A11	`07`	`1`		`@1 CRICKX (Béatrice)`
A14	`01`			`@1 Department of Dermatology, Bichat-Claude-Bernard Hospital, 48, rue Menri-Huchard @2 75018 Paris @3 FRA @Z 1 aut. @Z 2 aut. @Z 3 aut. @Z 4 aut. @Z 6 aut. @Z 7 aut.`
A14	`02`			`@1 Department of Anatomopathology, Bichat-Claude-Bernard Hospital, 48, rue Henri-Huchard @2 75018 Paris @3 FRA @Z 5 aut.`
A20				`@1 230-233`
A21				`@1 2001`
A23	`01`			`@0 ENG`
A43	`01`			`@1 INIST @2 22499 @5 354000097685090110`
A44				`@0 0000 @1 © 2001 INIST-CNRS. All rights reserved.`
A45				`@0 20 ref.`
A47	`01`	`1`		`@0 01-0310975`
A60				`@1 P`
A61				`@0 A`
A64	`01`	`1`		`@0 EJD. European journal of dermatology`
A66	`01`			`@0 FRA`
C01	`01`		`ENG`	@0 We report a typical case of bullous pemphigoid (BP) associated with a neurological disorder and study a possible link between neurological disorders and BP. An 84-year-old hemiplegic woman presented with unilateral BP on the hemiparetic side. BP was confirmed by histological and immunofluorescence data. The medical records of the previous 46 consecutive patients with BP were retrospectively analyzed (average age: 79; median age: 85). Thirty of the 46 patients with BP had neurological disorders. These disorders included dementia, epilepsy, multiple sclerosis, cerebral stroke, Parkinson's disease, gonadotropic adenoma, trembling, dyskinesia, lumbar spinal stenosis. In a control group of the 46 consecutive oldest patients (older than 71; average age: 82,5; median age: 80) with another skin disease referred during the previous two-year-period to our one-day-unit only, 13 patients had a neurological disorder. This study demonstrates that there is a high prevalence of neurological disorders in patients with BP (p = 0.0004). A prospective case control study with neurological examination and psychometrical evaluation is warranted to confirm these data. We speculate that neuroautoimmunity associated with the aging process or neurological disorders may be involved in pemphigoid development via an autoimmune response against dystonin which shares homology with bullous pemphigoid antigen 1. Bullous pemphigoid could be considered to be a marker of neurological disorder.
C02	`01`	`X`		`@0 002B08E`
C03	`01`	`X`	`FRE`	`@0 Pemphigoïde bulleuse @5 01`
C03	`01`	`X`	`ENG`	`@0 Bullous pemphigoid @5 01`
C03	`01`	`X`	`SPA`	`@0 Penfigoide buloso @5 01`
C03	`02`	`X`	`FRE`	`@0 Jambe @5 02`
C03	`02`	`X`	`ENG`	`@0 Leg @5 02`
C03	`02`	`X`	`SPA`	`@0 Pierna @5 02`
C03	`03`	`X`	`FRE`	`@0 Association @5 03`
C03	`03`	`X`	`ENG`	`@0 Association @5 03`
C03	`03`	`X`	`SPA`	`@0 Asociación @5 03`
C03	`04`	`X`	`FRE`	`@0 Hémiplégie @5 04`
C03	`04`	`X`	`ENG`	`@0 Hemiplegia @5 04`
C03	`04`	`X`	`SPA`	`@0 Hemiplejía @5 04`
C03	`05`	`X`	`FRE`	`@0 Etude cas @5 05`
C03	`05`	`X`	`ENG`	`@0 Case study @5 05`
C03	`05`	`X`	`SPA`	`@0 Estudio caso @5 05`
C03	`06`	`X`	`FRE`	`@0 Personne âgée @5 06`
C03	`06`	`X`	`ENG`	`@0 Elderly @5 06`
C03	`06`	`X`	`SPA`	`@0 Anciano @5 06`
C07	`01`	`X`	`FRE`	`@0 Homme`
C07	`01`	`X`	`ENG`	`@0 Human`
C07	`01`	`X`	`SPA`	`@0 Hombre`
C07	`02`	`X`	`FRE`	`@0 Système nerveux pathologie @5 45`
C07	`02`	`X`	`ENG`	`@0 Nervous system diseases @5 45`
C07	`02`	`X`	`SPA`	`@0 Sistema nervioso patología @5 45`
C07	`03`	`X`	`FRE`	`@0 Trouble neurologique @5 46`
C07	`03`	`X`	`ENG`	`@0 Neurological disorder @5 46`
C07	`03`	`X`	`SPA`	`@0 Trastorno neurológico @5 46`
C07	`04`	`X`	`FRE`	`@0 Trouble moteur @5 47`
C07	`04`	`X`	`ENG`	`@0 Motor system disorder @5 47`
C07	`04`	`X`	`SPA`	`@0 Trastorno motor @5 47`
C07	`05`	`X`	`FRE`	`@0 Maladie autoimmune @5 70`
C07	`05`	`X`	`ENG`	`@0 Autoimmune disease @5 70`
C07	`05`	`X`	`SPA`	`@0 Enfermedad autoinmune @5 70`
C07	`06`	`X`	`FRE`	`@0 Immunopathologie @5 71`
C07	`06`	`X`	`ENG`	`@0 Immunopathology @5 71`
C07	`06`	`X`	`SPA`	`@0 Inmunopatología @5 71`
C07	`07`	`X`	`FRE`	`@0 Peau pathologie @5 72`
C07	`07`	`X`	`ENG`	`@0 Skin disease @5 72`
C07	`07`	`X`	`SPA`	`@0 Piel patología @5 72`
C07	`08`	`X`	`FRE`	`@0 Dermatose bulleuse @5 73`
C07	`08`	`X`	`ENG`	`@0 Bullous dermatosis @5 73`
C07	`08`	`X`	`SPA`	`@0 Dermatosis bulosa @5 73`
N21				`@1 211`

Format Inist (serveur)

NO :	PASCAL 01-0310975 INIST
ET :	Bullous pemphigoid in a leg affected with hemiparesia : a possible relation of neurological diseases with bullous pemphigoid?
AU :	FOUREUR (Nicolas); DESCAMPS (Vincent); LEBRUN-VIGNES (Bénédicte); PICARD-DAHAN (Catherine); GROSSIN (Maggy); BELAICH (Stéphane); CRICKX (Béatrice)
AF :	Department of Dermatology, Bichat-Claude-Bernard Hospital, 48, rue Menri-Huchard/75018 Paris/France (1 aut., 2 aut., 3 aut., 4 aut., 6 aut., 7 aut.); Department of Anatomopathology, Bichat-Claude-Bernard Hospital, 48, rue Henri-Huchard/75018 Paris/France (5 aut.)
DT :	Publication en série; Niveau analytique
SO :	EJD. European journal of dermatology; ISSN 1167-1122; France; Da. 2001; Vol. 11; No. 3; Pp. 230-233; Bibl. 20 ref.
LA :	Anglais
EA :	We report a typical case of bullous pemphigoid (BP) associated with a neurological disorder and study a possible link between neurological disorders and BP. An 84-year-old hemiplegic woman presented with unilateral BP on the hemiparetic side. BP was confirmed by histological and immunofluorescence data. The medical records of the previous 46 consecutive patients with BP were retrospectively analyzed (average age: 79; median age: 85). Thirty of the 46 patients with BP had neurological disorders. These disorders included dementia, epilepsy, multiple sclerosis, cerebral stroke, Parkinson's disease, gonadotropic adenoma, trembling, dyskinesia, lumbar spinal stenosis. In a control group of the 46 consecutive oldest patients (older than 71; average age: 82,5; median age: 80) with another skin disease referred during the previous two-year-period to our one-day-unit only, 13 patients had a neurological disorder. This study demonstrates that there is a high prevalence of neurological disorders in patients with BP (p = 0.0004). A prospective case control study with neurological examination and psychometrical evaluation is warranted to confirm these data. We speculate that neuroautoimmunity associated with the aging process or neurological disorders may be involved in pemphigoid development via an autoimmune response against dystonin which shares homology with bullous pemphigoid antigen 1. Bullous pemphigoid could be considered to be a marker of neurological disorder.
CC :	002B08E
FD :	Pemphigoïde bulleuse; Jambe; Association; Hémiplégie; Etude cas; Personne âgée
FG :	Homme; Système nerveux pathologie; Trouble neurologique; Trouble moteur; Maladie autoimmune; Immunopathologie; Peau pathologie; Dermatose bulleuse
ED :	Bullous pemphigoid; Leg; Association; Hemiplegia; Case study; Elderly
EG :	Human; Nervous system diseases; Neurological disorder; Motor system disorder; Autoimmune disease; Immunopathology; Skin disease; Bullous dermatosis
SD :	Penfigoide buloso; Pierna; Asociación; Hemiplejía; Estudio caso; Anciano
LO :	INIST-22499.354000097685090110
ID :	01-0310975

Links to Exploration step

Pascal:01-0310975

Le document en format XML

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<front><div type="abstract" xml:lang="en">We report a typical case of bullous pemphigoid (BP) associated with a neurological disorder and study a possible link between neurological disorders and BP. An 84-year-old hemiplegic woman presented with unilateral BP on the hemiparetic side. BP was confirmed by histological and immunofluorescence data. The medical records of the previous 46 consecutive patients with BP were retrospectively analyzed (average age: 79; median age: 85). Thirty of the 46 patients with BP had neurological disorders. These disorders included dementia, epilepsy, multiple sclerosis, cerebral stroke, Parkinson's disease, gonadotropic adenoma, trembling, dyskinesia, lumbar spinal stenosis. In a control group of the 46 consecutive oldest patients (older than 71; average age: 82,5; median age: 80) with another skin disease referred during the previous two-year-period to our one-day-unit only, 13 patients had a neurological disorder. This study demonstrates that there is a high prevalence of neurological disorders in patients with BP (p = 0.0004). A prospective case control study with neurological examination and psychometrical evaluation is warranted to confirm these data. We speculate that neuroautoimmunity associated with the aging process or neurological disorders may be involved in pemphigoid development via an autoimmune response against dystonin which shares homology with bullous pemphigoid antigen 1. Bullous pemphigoid could be considered to be a marker of neurological disorder.</div>
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<fA11 i1="01" i2="1"><s1>FOUREUR (Nicolas)</s1>
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<fA14 i1="01"><s1>Department of Dermatology, Bichat-Claude-Bernard Hospital, 48, rue Menri-Huchard</s1>
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<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
</fA14>
<fA14 i1="02"><s1>Department of Anatomopathology, Bichat-Claude-Bernard Hospital, 48, rue Henri-Huchard</s1>
<s2>75018 Paris</s2>
<s3>FRA</s3>
<sZ>5 aut.</sZ>
</fA14>
<fA20><s1>230-233</s1>
</fA20>
<fA21><s1>2001</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
<fA43 i1="01"><s1>INIST</s1>
<s2>22499</s2>
<s5>354000097685090110</s5>
</fA43>
<fA44><s0>0000</s0>
<s1>© 2001 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45><s0>20 ref.</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>01-0310975</s0>
</fA47>
<fA60><s1>P</s1>
</fA60>
<fA61><s0>A</s0>
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<fA64 i1="01" i2="1"><s0>EJD. European journal of dermatology</s0>
</fA64>
<fA66 i1="01"><s0>FRA</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>We report a typical case of bullous pemphigoid (BP) associated with a neurological disorder and study a possible link between neurological disorders and BP. An 84-year-old hemiplegic woman presented with unilateral BP on the hemiparetic side. BP was confirmed by histological and immunofluorescence data. The medical records of the previous 46 consecutive patients with BP were retrospectively analyzed (average age: 79; median age: 85). Thirty of the 46 patients with BP had neurological disorders. These disorders included dementia, epilepsy, multiple sclerosis, cerebral stroke, Parkinson's disease, gonadotropic adenoma, trembling, dyskinesia, lumbar spinal stenosis. In a control group of the 46 consecutive oldest patients (older than 71; average age: 82,5; median age: 80) with another skin disease referred during the previous two-year-period to our one-day-unit only, 13 patients had a neurological disorder. This study demonstrates that there is a high prevalence of neurological disorders in patients with BP (p = 0.0004). A prospective case control study with neurological examination and psychometrical evaluation is warranted to confirm these data. We speculate that neuroautoimmunity associated with the aging process or neurological disorders may be involved in pemphigoid development via an autoimmune response against dystonin which shares homology with bullous pemphigoid antigen 1. Bullous pemphigoid could be considered to be a marker of neurological disorder.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B08E</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Pemphigoïde bulleuse</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Bullous pemphigoid</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Penfigoide buloso</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Jambe</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Leg</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Pierna</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Association</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Association</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Asociación</s0>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Hémiplégie</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Hemiplegia</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Hemiplejía</s0>
<s5>04</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Etude cas</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Case study</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Estudio caso</s0>
<s5>05</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Personne âgée</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Elderly</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Anciano</s0>
<s5>06</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Homme</s0>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Human</s0>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Hombre</s0>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Système nerveux pathologie</s0>
<s5>45</s5>
</fC07>
<fC07 i1="02" i2="X" l="ENG"><s0>Nervous system diseases</s0>
<s5>45</s5>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Sistema nervioso patología</s0>
<s5>45</s5>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Trouble neurologique</s0>
<s5>46</s5>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Neurological disorder</s0>
<s5>46</s5>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Trastorno neurológico</s0>
<s5>46</s5>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Trouble moteur</s0>
<s5>47</s5>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Motor system disorder</s0>
<s5>47</s5>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Trastorno motor</s0>
<s5>47</s5>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Maladie autoimmune</s0>
<s5>70</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Autoimmune disease</s0>
<s5>70</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Enfermedad autoinmune</s0>
<s5>70</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Immunopathologie</s0>
<s5>71</s5>
</fC07>
<fC07 i1="06" i2="X" l="ENG"><s0>Immunopathology</s0>
<s5>71</s5>
</fC07>
<fC07 i1="06" i2="X" l="SPA"><s0>Inmunopatología</s0>
<s5>71</s5>
</fC07>
<fC07 i1="07" i2="X" l="FRE"><s0>Peau pathologie</s0>
<s5>72</s5>
</fC07>
<fC07 i1="07" i2="X" l="ENG"><s0>Skin disease</s0>
<s5>72</s5>
</fC07>
<fC07 i1="07" i2="X" l="SPA"><s0>Piel patología</s0>
<s5>72</s5>
</fC07>
<fC07 i1="08" i2="X" l="FRE"><s0>Dermatose bulleuse</s0>
<s5>73</s5>
</fC07>
<fC07 i1="08" i2="X" l="ENG"><s0>Bullous dermatosis</s0>
<s5>73</s5>
</fC07>
<fC07 i1="08" i2="X" l="SPA"><s0>Dermatosis bulosa</s0>
<s5>73</s5>
</fC07>
<fN21><s1>211</s1>
</fN21>
</pA>
</standard>
<server><NO>PASCAL 01-0310975 INIST</NO>
<ET>Bullous pemphigoid in a leg affected with hemiparesia : a possible relation of neurological diseases with bullous pemphigoid?</ET>
<AU>FOUREUR (Nicolas); DESCAMPS (Vincent); LEBRUN-VIGNES (Bénédicte); PICARD-DAHAN (Catherine); GROSSIN (Maggy); BELAICH (Stéphane); CRICKX (Béatrice)</AU>
<AF>Department of Dermatology, Bichat-Claude-Bernard Hospital, 48, rue Menri-Huchard/75018 Paris/France (1 aut., 2 aut., 3 aut., 4 aut., 6 aut., 7 aut.); Department of Anatomopathology, Bichat-Claude-Bernard Hospital, 48, rue Henri-Huchard/75018 Paris/France (5 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>EJD. European journal of dermatology; ISSN 1167-1122; France; Da. 2001; Vol. 11; No. 3; Pp. 230-233; Bibl. 20 ref.</SO>
<LA>Anglais</LA>
<EA>We report a typical case of bullous pemphigoid (BP) associated with a neurological disorder and study a possible link between neurological disorders and BP. An 84-year-old hemiplegic woman presented with unilateral BP on the hemiparetic side. BP was confirmed by histological and immunofluorescence data. The medical records of the previous 46 consecutive patients with BP were retrospectively analyzed (average age: 79; median age: 85). Thirty of the 46 patients with BP had neurological disorders. These disorders included dementia, epilepsy, multiple sclerosis, cerebral stroke, Parkinson's disease, gonadotropic adenoma, trembling, dyskinesia, lumbar spinal stenosis. In a control group of the 46 consecutive oldest patients (older than 71; average age: 82,5; median age: 80) with another skin disease referred during the previous two-year-period to our one-day-unit only, 13 patients had a neurological disorder. This study demonstrates that there is a high prevalence of neurological disorders in patients with BP (p = 0.0004). A prospective case control study with neurological examination and psychometrical evaluation is warranted to confirm these data. We speculate that neuroautoimmunity associated with the aging process or neurological disorders may be involved in pemphigoid development via an autoimmune response against dystonin which shares homology with bullous pemphigoid antigen 1. Bullous pemphigoid could be considered to be a marker of neurological disorder.</EA>
<CC>002B08E</CC>
<FD>Pemphigoïde bulleuse; Jambe; Association; Hémiplégie; Etude cas; Personne âgée</FD>
<FG>Homme; Système nerveux pathologie; Trouble neurologique; Trouble moteur; Maladie autoimmune; Immunopathologie; Peau pathologie; Dermatose bulleuse</FG>
<ED>Bullous pemphigoid; Leg; Association; Hemiplegia; Case study; Elderly</ED>
<EG>Human; Nervous system diseases; Neurological disorder; Motor system disorder; Autoimmune disease; Immunopathology; Skin disease; Bullous dermatosis</EG>
<SD>Penfigoide buloso; Pierna; Asociación; Hemiplejía; Estudio caso; Anciano</SD>
<LO>INIST-22499.354000097685090110</LO>
<ID>01-0310975</ID>
</server>
</inist>
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Bullous pemphigoid in a leg affected with hemiparesia : a possible relation of neurological diseases with bullous pemphigoid?

Bullous pemphigoid in a leg affected with hemiparesia : a possible relation of neurological diseases with bullous pemphigoid?

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