La maladie de Parkinson en France (serveur d'exploration)

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Prevalence and phenomenology of olfactory hallucinations in Parkinson's disease

Identifieur interne : 000215 ( PascalFrancis/Corpus ); précédent : 000214; suivant : 000216

Prevalence and phenomenology of olfactory hallucinations in Parkinson's disease

Auteurs : Stephanie Bannier ; Jean Louis Berdague ; Isabelle Rieu ; Ingrid De Chazeron ; Ana Marques ; Philippe Derost ; Miguel Ulla ; Pierre-Michel Llorca ; Franck Durif

Source :

RBID : Pascal:12-0384347

Descripteurs français

English descriptors

Abstract

Background Although visual hallucinations in Parkinson's disease (PD) have been described in several major studies, little is known about olfactory hallucinations (0Hs). Methods The authors performed a detailed analysis of OHs in a cohort of 87 Parkinsonian patients to estimate the prevalence of OHs and describe their phenomenology. They also evaluated smelling abilities in terms of detection and identification. Assessment of both, OHs and olfactory function, was also performed using a control group of 40 normal subjects. Results Nine patients exhibited OHs compared with none of the controls, giving a prevalence of 10% for OHs in patients. OHs were described as rare, short-lasting, unpleasant odours which are not frightening since clearly identified by the patient as hallucinations. Parkinsonian patients with OHs exhibited olfactory impairment of detection and identification compared with controls, but there was no difference in their olfactory abilities from Parkinsonian patients without OHs. Conclusions In conclusion, OHs should be added to the list of non-motor PD symptoms that can occur early or late in the course of PD. The authors' study did not reveal any significant difference in terms of olfactory abilities between patients with or without OHs. However, olfactory impairment is well documented in Parkinsonian patients and cannot be totally ruled out as a risk factor for OHs. The authors recognise that complex mechanisms are probably involved in this phenomenon.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

pA  
A01 01  1    @0 0022-3050
A02 01      @0 JNNPAU
A03   1    @0 J. neurol. neurosurg. psychiatry
A05       @2 83
A06       @2 10
A08 01  1  ENG  @1 Prevalence and phenomenology of olfactory hallucinations in Parkinson's disease
A11 01  1    @1 BANNIER (Stephanie)
A11 02  1    @1 BERDAGUE (Jean Louis)
A11 03  1    @1 RIEU (Isabelle)
A11 04  1    @1 DE CHAZERON (Ingrid)
A11 05  1    @1 MARQUES (Ana)
A11 06  1    @1 DEROST (Philippe)
A11 07  1    @1 ULLA (Miguel)
A11 08  1    @1 LLORCA (Pierre-Michel)
A11 09  1    @1 DURIF (Franck)
A14 01      @1 CHU Clermont-Ferrand, Neurology Department @2 Clermont-Ferrand @3 FRA @Z 1 aut. @Z 3 aut. @Z 5 aut. @Z 6 aut. @Z 7 aut. @Z 9 aut.
A14 02      @1 Univ Clermont 1, UFR Medecine @2 Clermont-Ferrand @3 FRA @Z 1 aut. @Z 3 aut. @Z 4 aut. @Z 5 aut. @Z 6 aut. @Z 7 aut. @Z 8 aut. @Z 9 aut.
A14 03      @1 INRA, UR454 Microbiologie @2 Saint-Genès Champanelle @3 FRA @Z 2 aut.
A14 04      @1 CHU Clermont-Ferrand, Department of Psychiatry B @2 Clermont-Ferrand @3 FRA @Z 4 aut. @Z 8 aut.
A20       @1 1019-1021
A21       @1 2012
A23 01      @0 ENG
A43 01      @1 INIST @2 6015 @5 354000502029290180
A44       @0 0000 @1 © 2012 INIST-CNRS. All rights reserved.
A45       @0 15 ref.
A47 01  1    @0 12-0384347
A60       @1 P @3 CC
A61       @0 A
A64 01  1    @0 Journal of neurology, neurosurgery and psychiatry
A66 01      @0 GBR
C01 01    ENG  @0 Background Although visual hallucinations in Parkinson's disease (PD) have been described in several major studies, little is known about olfactory hallucinations (0Hs). Methods The authors performed a detailed analysis of OHs in a cohort of 87 Parkinsonian patients to estimate the prevalence of OHs and describe their phenomenology. They also evaluated smelling abilities in terms of detection and identification. Assessment of both, OHs and olfactory function, was also performed using a control group of 40 normal subjects. Results Nine patients exhibited OHs compared with none of the controls, giving a prevalence of 10% for OHs in patients. OHs were described as rare, short-lasting, unpleasant odours which are not frightening since clearly identified by the patient as hallucinations. Parkinsonian patients with OHs exhibited olfactory impairment of detection and identification compared with controls, but there was no difference in their olfactory abilities from Parkinsonian patients without OHs. Conclusions In conclusion, OHs should be added to the list of non-motor PD symptoms that can occur early or late in the course of PD. The authors' study did not reveal any significant difference in terms of olfactory abilities between patients with or without OHs. However, olfactory impairment is well documented in Parkinsonian patients and cannot be totally ruled out as a risk factor for OHs. The authors recognise that complex mechanisms are probably involved in this phenomenon.
C02 01  X    @0 002B17
C02 02  X    @0 002B17G
C03 01  X  FRE  @0 Hallucination @5 01
C03 01  X  ENG  @0 Hallucination @5 01
C03 01  X  SPA  @0 Alucinación @5 01
C03 02  X  FRE  @0 Maladie de Parkinson @2 NM @5 02
C03 02  X  ENG  @0 Parkinson disease @2 NM @5 02
C03 02  X  SPA  @0 Parkinson enfermedad @2 NM @5 02
C03 03  X  FRE  @0 Pathologie du système nerveux @5 03
C03 03  X  ENG  @0 Nervous system diseases @5 03
C03 03  X  SPA  @0 Sistema nervioso patología @5 03
C03 04  X  FRE  @0 Prévalence @5 09
C03 04  X  ENG  @0 Prevalence @5 09
C03 04  X  SPA  @0 Prevalencia @5 09
C07 01  X  FRE  @0 Pathologie de l'encéphale @5 37
C07 01  X  ENG  @0 Cerebral disorder @5 37
C07 01  X  SPA  @0 Encéfalo patología @5 37
C07 02  X  FRE  @0 Syndrome extrapyramidal @5 38
C07 02  X  ENG  @0 Extrapyramidal syndrome @5 38
C07 02  X  SPA  @0 Extrapiramidal síndrome @5 38
C07 03  X  FRE  @0 Maladie dégénérative @5 39
C07 03  X  ENG  @0 Degenerative disease @5 39
C07 03  X  SPA  @0 Enfermedad degenerativa @5 39
C07 04  X  FRE  @0 Pathologie du système nerveux central @5 40
C07 04  X  ENG  @0 Central nervous system disease @5 40
C07 04  X  SPA  @0 Sistema nervosio central patología @5 40
N21       @1 296
N44 01      @1 OTO
N82       @1 OTO

Format Inist (serveur)

NO : PASCAL 12-0384347 INIST
ET : Prevalence and phenomenology of olfactory hallucinations in Parkinson's disease
AU : BANNIER (Stephanie); BERDAGUE (Jean Louis); RIEU (Isabelle); DE CHAZERON (Ingrid); MARQUES (Ana); DEROST (Philippe); ULLA (Miguel); LLORCA (Pierre-Michel); DURIF (Franck)
AF : CHU Clermont-Ferrand, Neurology Department/Clermont-Ferrand/France (1 aut., 3 aut., 5 aut., 6 aut., 7 aut., 9 aut.); Univ Clermont 1, UFR Medecine/Clermont-Ferrand/France (1 aut., 3 aut., 4 aut., 5 aut., 6 aut., 7 aut., 8 aut., 9 aut.); INRA, UR454 Microbiologie/Saint-Genès Champanelle/France (2 aut.); CHU Clermont-Ferrand, Department of Psychiatry B/Clermont-Ferrand/France (4 aut., 8 aut.)
DT : Publication en série; Courte communication, note brève; Niveau analytique
SO : Journal of neurology, neurosurgery and psychiatry; ISSN 0022-3050; Coden JNNPAU; Royaume-Uni; Da. 2012; Vol. 83; No. 10; Pp. 1019-1021; Bibl. 15 ref.
LA : Anglais
EA : Background Although visual hallucinations in Parkinson's disease (PD) have been described in several major studies, little is known about olfactory hallucinations (0Hs). Methods The authors performed a detailed analysis of OHs in a cohort of 87 Parkinsonian patients to estimate the prevalence of OHs and describe their phenomenology. They also evaluated smelling abilities in terms of detection and identification. Assessment of both, OHs and olfactory function, was also performed using a control group of 40 normal subjects. Results Nine patients exhibited OHs compared with none of the controls, giving a prevalence of 10% for OHs in patients. OHs were described as rare, short-lasting, unpleasant odours which are not frightening since clearly identified by the patient as hallucinations. Parkinsonian patients with OHs exhibited olfactory impairment of detection and identification compared with controls, but there was no difference in their olfactory abilities from Parkinsonian patients without OHs. Conclusions In conclusion, OHs should be added to the list of non-motor PD symptoms that can occur early or late in the course of PD. The authors' study did not reveal any significant difference in terms of olfactory abilities between patients with or without OHs. However, olfactory impairment is well documented in Parkinsonian patients and cannot be totally ruled out as a risk factor for OHs. The authors recognise that complex mechanisms are probably involved in this phenomenon.
CC : 002B17; 002B17G
FD : Hallucination; Maladie de Parkinson; Pathologie du système nerveux; Prévalence
FG : Pathologie de l'encéphale; Syndrome extrapyramidal; Maladie dégénérative; Pathologie du système nerveux central
ED : Hallucination; Parkinson disease; Nervous system diseases; Prevalence
EG : Cerebral disorder; Extrapyramidal syndrome; Degenerative disease; Central nervous system disease
SD : Alucinación; Parkinson enfermedad; Sistema nervioso patología; Prevalencia
LO : INIST-6015.354000502029290180
ID : 12-0384347

Links to Exploration step

Pascal:12-0384347

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<title level="j" type="main">Journal of neurology, neurosurgery and psychiatry</title>
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<title level="j" type="main">Journal of neurology, neurosurgery and psychiatry</title>
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<term>Prevalence</term>
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<term>Hallucination</term>
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<div type="abstract" xml:lang="en">Background Although visual hallucinations in Parkinson's disease (PD) have been described in several major studies, little is known about olfactory hallucinations (0Hs). Methods The authors performed a detailed analysis of OHs in a cohort of 87 Parkinsonian patients to estimate the prevalence of OHs and describe their phenomenology. They also evaluated smelling abilities in terms of detection and identification. Assessment of both, OHs and olfactory function, was also performed using a control group of 40 normal subjects. Results Nine patients exhibited OHs compared with none of the controls, giving a prevalence of 10% for OHs in patients. OHs were described as rare, short-lasting, unpleasant odours which are not frightening since clearly identified by the patient as hallucinations. Parkinsonian patients with OHs exhibited olfactory impairment of detection and identification compared with controls, but there was no difference in their olfactory abilities from Parkinsonian patients without OHs. Conclusions In conclusion, OHs should be added to the list of non-motor PD symptoms that can occur early or late in the course of PD. The authors' study did not reveal any significant difference in terms of olfactory abilities between patients with or without OHs. However, olfactory impairment is well documented in Parkinsonian patients and cannot be totally ruled out as a risk factor for OHs. The authors recognise that complex mechanisms are probably involved in this phenomenon.</div>
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<ET>Prevalence and phenomenology of olfactory hallucinations in Parkinson's disease</ET>
<AU>BANNIER (Stephanie); BERDAGUE (Jean Louis); RIEU (Isabelle); DE CHAZERON (Ingrid); MARQUES (Ana); DEROST (Philippe); ULLA (Miguel); LLORCA (Pierre-Michel); DURIF (Franck)</AU>
<AF>CHU Clermont-Ferrand, Neurology Department/Clermont-Ferrand/France (1 aut., 3 aut., 5 aut., 6 aut., 7 aut., 9 aut.); Univ Clermont 1, UFR Medecine/Clermont-Ferrand/France (1 aut., 3 aut., 4 aut., 5 aut., 6 aut., 7 aut., 8 aut., 9 aut.); INRA, UR454 Microbiologie/Saint-Genès Champanelle/France (2 aut.); CHU Clermont-Ferrand, Department of Psychiatry B/Clermont-Ferrand/France (4 aut., 8 aut.)</AF>
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<SO>Journal of neurology, neurosurgery and psychiatry; ISSN 0022-3050; Coden JNNPAU; Royaume-Uni; Da. 2012; Vol. 83; No. 10; Pp. 1019-1021; Bibl. 15 ref.</SO>
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<EA>Background Although visual hallucinations in Parkinson's disease (PD) have been described in several major studies, little is known about olfactory hallucinations (0Hs). Methods The authors performed a detailed analysis of OHs in a cohort of 87 Parkinsonian patients to estimate the prevalence of OHs and describe their phenomenology. They also evaluated smelling abilities in terms of detection and identification. Assessment of both, OHs and olfactory function, was also performed using a control group of 40 normal subjects. Results Nine patients exhibited OHs compared with none of the controls, giving a prevalence of 10% for OHs in patients. OHs were described as rare, short-lasting, unpleasant odours which are not frightening since clearly identified by the patient as hallucinations. Parkinsonian patients with OHs exhibited olfactory impairment of detection and identification compared with controls, but there was no difference in their olfactory abilities from Parkinsonian patients without OHs. Conclusions In conclusion, OHs should be added to the list of non-motor PD symptoms that can occur early or late in the course of PD. The authors' study did not reveal any significant difference in terms of olfactory abilities between patients with or without OHs. However, olfactory impairment is well documented in Parkinsonian patients and cannot be totally ruled out as a risk factor for OHs. The authors recognise that complex mechanisms are probably involved in this phenomenon.</EA>
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