La maladie de Parkinson en France (serveur d'exploration)

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Orthostatic tremor: a cerebellar pathology?

Identifieur interne : 001A55 ( Ncbi/Merge ); précédent : 001A54; suivant : 001A56

Orthostatic tremor: a cerebellar pathology?

Auteurs : Cécile Gallea [France] ; Traian Popa [France] ; Daniel García-Lorenzo [France] ; Romain Valabregue [France] ; André-Pierre Legrand [France] ; Emmanuelle Apartis [France] ; Lea Marais [France] ; Bertrand Degos [France] ; Cecile Hubsch [France] ; Sara Fernández-Vidal [France] ; Eric Bardinet [France] ; Emmanuel Roze [France] ; Stéphane Lehéricy [France] ; Sabine Meunier [France] ; Marie Vidailhet [France]

Source :

RBID : PMC:4958903

Abstract

See Muthuraman et al. (doi:10.1093/aww164) for a scientific commentary on this article.

The pathophysiology of orthostatic tremor is unclear. Using neuroimaging to investigate the cerebellar motor pathways in patients, Gallea et al. reveal anatomo-functional changes in the cerebellar vermis, lateral cerebellum and supplementary motor area. Repetitive transcranial cerebellar stimulation reduces the amplitude of the tremor frequency peak and modifies cerebello-cortical connectivity.


Url:
DOI: 10.1093/brain/aww140
PubMed: 27329770
PubMed Central: 4958903

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PMC:4958903

Le document en format XML

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<name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name>
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<title xml:lang="en" level="a" type="main">Orthostatic tremor: a cerebellar pathology?</title>
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<name sortKey="Gallea, Cecile" sort="Gallea, Cecile" uniqKey="Gallea C" first="Cécile" last="Gallea">Cécile Gallea</name>
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<name sortKey="Garcia Lorenzo, Daniel" sort="Garcia Lorenzo, Daniel" uniqKey="Garcia Lorenzo D" first="Daniel" last="García-Lorenzo">Daniel García-Lorenzo</name>
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<name sortKey="Valabregue, Romain" sort="Valabregue, Romain" uniqKey="Valabregue R" first="Romain" last="Valabregue">Romain Valabregue</name>
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<author>
<name sortKey="Marais, Lea" sort="Marais, Lea" uniqKey="Marais L" first="Lea" last="Marais">Lea Marais</name>
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<name sortKey="Roze, Emmanuel" sort="Roze, Emmanuel" uniqKey="Roze E" first="Emmanuel" last="Roze">Emmanuel Roze</name>
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<name sortKey="Lehericy, Stephane" sort="Lehericy, Stephane" uniqKey="Lehericy S" first="Stéphane" last="Lehéricy">Stéphane Lehéricy</name>
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<name sortKey="Meunier, Sabine" sort="Meunier, Sabine" uniqKey="Meunier S" first="Sabine" last="Meunier">Sabine Meunier</name>
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<nlm:aff id="aww140-AFF2">2 Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127, Paris, France</nlm:aff>
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<nlm:aff id="aww140-AFF3">3 CNRS, UMR 7225, Paris, France</nlm:aff>
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</placeName>
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<country xml:lang="fr">France</country>
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<placeName>
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</placeName>
</affiliation>
</author>
<author>
<name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name>
<affiliation wicri:level="3">
<nlm:aff id="aww140-AFF2">2 Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127, Paris, France</nlm:aff>
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<placeName>
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</placeName>
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<affiliation wicri:level="3">
<nlm:aff id="aww140-AFF4">4 Inserm, U 1127, Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
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<placeName>
<region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3">
<nlm:aff id="aww140-AFF8">8 AP-HP, Hôpital de la Pitié Salpêtrière, Département de Neurologie, Paris, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>8 AP-HP, Hôpital de la Pitié Salpêtrière, Département de Neurologie, Paris</wicri:regionArea>
<placeName>
<region type="region">Île-de-France</region>
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</author>
</analytic>
<series>
<title level="j">Brain</title>
<idno type="ISSN">0006-8950</idno>
<idno type="eISSN">1460-2156</idno>
<imprint>
<date when="2016">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass></textClass>
</profileDesc>
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<front>
<div type="abstract" xml:lang="en">
<p>
<bold>See Muthuraman
<italic>et al</italic>
. (doi:
<related-article id="d36e409" related-article-type="companion" ext-link-type="doi" xlink:href="10.1093/brain/aww164">10.1093/aww164</related-article>
) for a scientific commentary on this article.</bold>
</p>
<p>The pathophysiology of orthostatic tremor is unclear. Using neuroimaging to investigate the cerebellar motor pathways in patients, Gallea
<italic>et al</italic>
. reveal anatomo-functional changes in the cerebellar vermis, lateral cerebellum and supplementary motor area. Repetitive transcranial cerebellar stimulation reduces the amplitude of the tremor frequency peak and modifies cerebello-cortical connectivity.</p>
</div>
</front>
<back>
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<pmc article-type="research-article">
<pmc-dir>properties open_access</pmc-dir>
<front>
<journal-meta>
<journal-id journal-id-type="nlm-ta">Brain</journal-id>
<journal-id journal-id-type="iso-abbrev">Brain</journal-id>
<journal-id journal-id-type="publisher-id">brainj</journal-id>
<journal-id journal-id-type="hwp">brain</journal-id>
<journal-title-group>
<journal-title>Brain</journal-title>
</journal-title-group>
<issn pub-type="ppub">0006-8950</issn>
<issn pub-type="epub">1460-2156</issn>
<publisher>
<publisher-name>Oxford University Press</publisher-name>
</publisher>
</journal-meta>
<article-meta>
<article-id pub-id-type="pmid">27329770</article-id>
<article-id pub-id-type="pmc">4958903</article-id>
<article-id pub-id-type="doi">10.1093/brain/aww140</article-id>
<article-id pub-id-type="publisher-id">aww140</article-id>
<article-categories>
<subj-group subj-group-type="heading">
<subject>Original Articles</subject>
</subj-group>
<subj-group subj-group-type="hwp-journal-coll">
<subject>1040</subject>
</subj-group>
</article-categories>
<title-group>
<article-title>Orthostatic tremor: a cerebellar pathology?</article-title>
</title-group>
<contrib-group>
<contrib contrib-type="author" corresp="yes">
<name>
<surname>Gallea</surname>
<given-names>Cécile</given-names>
</name>
<xref ref-type="aff" rid="aww140-AFF1">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF3">
<sup>3</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF4">
<sup>4</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF5">
<sup>5</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Popa</surname>
<given-names>Traian</given-names>
</name>
<xref ref-type="aff" rid="aww140-AFF1">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF3">
<sup>3</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF4">
<sup>4</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>García-Lorenzo</surname>
<given-names>Daniel</given-names>
</name>
<xref ref-type="aff" rid="aww140-AFF1">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF3">
<sup>3</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF4">
<sup>4</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF5">
<sup>5</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Valabregue</surname>
<given-names>Romain</given-names>
</name>
<xref ref-type="aff" rid="aww140-AFF1">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF3">
<sup>3</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF4">
<sup>4</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF5">
<sup>5</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Legrand</surname>
<given-names>André-Pierre</given-names>
</name>
<xref ref-type="aff" rid="aww140-AFF6">
<sup>6</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Apartis</surname>
<given-names>Emmanuelle</given-names>
</name>
<xref ref-type="aff" rid="aww140-AFF2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF3">
<sup>3</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF4">
<sup>4</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF7">
<sup>7</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Marais</surname>
<given-names>Lea</given-names>
</name>
<xref ref-type="aff" rid="aww140-AFF1">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF3">
<sup>3</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF4">
<sup>4</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF5">
<sup>5</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Degos</surname>
<given-names>Bertrand</given-names>
</name>
<xref ref-type="aff" rid="aww140-AFF2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF3">
<sup>3</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF4">
<sup>4</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF8">
<sup>8</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Hubsch</surname>
<given-names>Cecile</given-names>
</name>
<xref ref-type="aff" rid="aww140-AFF2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF3">
<sup>3</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF4">
<sup>4</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF8">
<sup>8</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Fernández-Vidal</surname>
<given-names>Sara</given-names>
</name>
<xref ref-type="aff" rid="aww140-AFF1">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF3">
<sup>3</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF4">
<sup>4</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Bardinet</surname>
<given-names>Eric</given-names>
</name>
<xref ref-type="aff" rid="aww140-AFF1">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF3">
<sup>3</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF4">
<sup>4</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Roze</surname>
<given-names>Emmanuel</given-names>
</name>
<xref ref-type="aff" rid="aww140-AFF2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF3">
<sup>3</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF4">
<sup>4</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF8">
<sup>8</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Lehéricy</surname>
<given-names>Stéphane</given-names>
</name>
<xref ref-type="aff" rid="aww140-AFF1">
<sup>1</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF3">
<sup>3</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF4">
<sup>4</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF5">
<sup>5</sup>
</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Meunier</surname>
<given-names>Sabine</given-names>
</name>
<xref ref-type="aff" rid="aww140-AFF2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF3">
<sup>3</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF4">
<sup>4</sup>
</xref>
<xref ref-type="author-notes" rid="aww140-FN1">*</xref>
</contrib>
<contrib contrib-type="author">
<name>
<surname>Vidailhet</surname>
<given-names>Marie</given-names>
</name>
<xref ref-type="aff" rid="aww140-AFF2">
<sup>2</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF3">
<sup>3</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF4">
<sup>4</sup>
</xref>
<xref ref-type="aff" rid="aww140-AFF8">
<sup>8</sup>
</xref>
<xref ref-type="author-notes" rid="aww140-FN1">*</xref>
</contrib>
<aff id="aww140-AFF1">1 Centre de NeuroImagerie de Recherche – Institut du Cerveau et de la Moelle épinière, ICM, Paris, France</aff>
<aff id="aww140-AFF2">2 Sorbonne Universités, UPMC Univ Paris 06, UMR S 1127, Paris, France</aff>
<aff id="aww140-AFF3">3 CNRS, UMR 7225, Paris, France</aff>
<aff id="aww140-AFF4">4 Inserm, U 1127, Paris, France</aff>
<aff id="aww140-AFF5">5 AP-HP, Hôpital de la Pitié Salpêtrière, Département de Neuroradiologie, Paris, France</aff>
<aff id="aww140-AFF6">6 ESPCI, Paris Sciences, Paris, France</aff>
<aff id="aww140-AFF7">7 AP-HP, Hôpital de Saint-Antoine, Département de Neurologie, Paris, France</aff>
<aff id="aww140-AFF8">8 AP-HP, Hôpital de la Pitié Salpêtrière, Département de Neurologie, Paris, France</aff>
</contrib-group>
<author-notes>
<corresp id="aww140-COR1">Correspondence to: Cecile Gallea, Centre de Neuroimagerie de Recherche – CENIR, Institut du Cerveau et de la Moelle épinière – ICM, Groupe Hospitalier Pitié-Salpêtrière, 75651 Paris, cedex 13 France, e-mail:
<email>felix.cervantes@ars.usda.gov</email>
</corresp>
<fn id="aww140-FN1">
<p>*
<bold>These authors contributed equally to this work.</bold>
</p>
</fn>
<fn id="aww140-FN2">
<p>See Muthuraman
<italic>et al</italic>
. (doi:
<related-article id="d36e345" related-article-type="companion" ext-link-type="doi" xlink:href="10.1093/brain/aww164">10.1093/aww164</related-article>
) for a scientific commentary on this article.</p>
</fn>
</author-notes>
<pub-date pub-type="ppub">
<month>8</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="epub">
<day>21</day>
<month>6</month>
<year>2016</year>
</pub-date>
<pub-date pub-type="pmc-release">
<day>21</day>
<month>6</month>
<year>2016</year>
</pub-date>
<pmc-comment> PMC Release delay is 0 months and 0 days and was based on the . </pmc-comment>
<volume>139</volume>
<issue>8</issue>
<fpage>2182</fpage>
<lpage>2197</lpage>
<history>
<date date-type="received">
<day>13</day>
<month>1</month>
<year>2016</year>
</date>
<date date-type="rev-recd">
<day>29</day>
<month>3</month>
<year>2016</year>
</date>
<date date-type="accepted">
<day>22</day>
<month>4</month>
<year>2016</year>
</date>
</history>
<permissions>
<copyright-statement>© The Author (2016). Published by Oxford University Press on behalf of the Guarantors of Brain. All rights reserved. For Permissions, please email: journals.permissions@oup.com</copyright-statement>
<copyright-year>2016</copyright-year>
<license xlink:href="http://creativecommons.org/licenses/by-nc/4.0/" license-type="creative-commons">
<license-p>This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (
<ext-link ext-link-type="uri" xlink:href="http://creativecommons.org/licenses/by-nc/4.0/">http://creativecommons.org/licenses/by-nc/4.0/</ext-link>
), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com</license-p>
</license>
</permissions>
<abstract abstract-type="precise">
<p>
<bold>See Muthuraman
<italic>et al</italic>
. (doi:
<related-article id="d36e409" related-article-type="companion" ext-link-type="doi" xlink:href="10.1093/brain/aww164">10.1093/aww164</related-article>
) for a scientific commentary on this article.</bold>
</p>
<p>The pathophysiology of orthostatic tremor is unclear. Using neuroimaging to investigate the cerebellar motor pathways in patients, Gallea
<italic>et al</italic>
. reveal anatomo-functional changes in the cerebellar vermis, lateral cerebellum and supplementary motor area. Repetitive transcranial cerebellar stimulation reduces the amplitude of the tremor frequency peak and modifies cerebello-cortical connectivity.</p>
</abstract>
<abstract abstract-type="graphical">
<p>
<fig id="fig1g" fig-type="featured" orientation="portrait" position="float">
<caption>
<p>
<bold>See Muthuraman
<italic>et al</italic>
. (doi:
<related-article id="d36e428" related-article-type="companion" ext-link-type="doi" xlink:href="10.1093/brain/aww164">10.1093/aww164</related-article>
) for a scientific commentary on this article.</bold>
</p>
<p>The pathophysiology of orthostatic tremor is unclear. Using neuroimaging to investigate the cerebellar motor pathways in patients, Gallea
<italic>et al</italic>
. reveal anatomo-functional changes in the cerebellar vermis, lateral cerebellum and supplementary motor area. Repetitive transcranial cerebellar stimulation reduces the amplitude of the tremor frequency peak and modifies cerebello-cortical connectivity.</p>
</caption>
<graphic xlink:href="aww140fig1g"></graphic>
</fig>
</p>
</abstract>
<abstract>
<p>
<bold>See Muthuraman
<italic>et al</italic>
. (doi:
<related-article id="d36e445" related-article-type="companion" ext-link-type="doi" xlink:href="10.1093/brain/aww164">10.1093/aww164</related-article>
) for a scientific commentary on this article.</bold>
</p>
<p>Primary orthostatic tremor is characterized by high frequency tremor affecting the legs and trunk during the standing position. Cerebellar defects were suggested in orthostatic tremor without direct evidence. We aimed to characterize the anatomo-functional defects of the cerebellar motor pathways in orthostatic tremor. We used multimodal neuroimaging to compare 17 patients with orthostatic tremor and 17 age- and gender-matched healthy volunteers. Nine of the patients with orthostatic tremor underwent repetitive transcranial stimulation applied over the cerebellum during five consecutive days. We quantified the duration of standing position and tremor severity through electromyographic recordings. Compared to healthy volunteers, grey matter volume in patients with orthostatic tremor was (i) increased in the cerebellar vermis and correlated positively with the duration of the standing position; and (ii) increased in the supplementary motor area and decreased in the lateral cerebellum, which both correlated with the disease duration. Functional connectivity between the lateral cerebellum and the supplementary motor area was abnormally increased in patients with orthostatic tremor, and correlated positively with tremor severity. After repetitive transcranial stimulation, tremor severity and functional connectivity between the lateral cerebellum and the supplementary motor area were reduced. We provide an explanation for orthostatic tremor pathophysiology, and demonstrate the functional relevance of cerebello-thalamo-cortical connections in tremor related to cerebellar defects.</p>
</abstract>
<kwd-group kwd-group-type="keywords">
<kwd>cerebellar function</kwd>
<kwd>motor cortex</kwd>
<kwd>movement disorder</kwd>
<kwd>tremor</kwd>
<kwd>frontal lobe</kwd>
</kwd-group>
<counts>
<page-count count="16"></page-count>
</counts>
</article-meta>
</front>
</pmc>
<affiliations>
<list>
<country>
<li>France</li>
</country>
<region>
<li>Île-de-France</li>
</region>
<settlement>
<li>Paris</li>
</settlement>
</list>
<tree>
<country name="France">
<region name="Île-de-France">
<name sortKey="Gallea, Cecile" sort="Gallea, Cecile" uniqKey="Gallea C" first="Cécile" last="Gallea">Cécile Gallea</name>
</region>
<name sortKey="Apartis, Emmanuelle" sort="Apartis, Emmanuelle" uniqKey="Apartis E" first="Emmanuelle" last="Apartis">Emmanuelle Apartis</name>
<name sortKey="Apartis, Emmanuelle" sort="Apartis, Emmanuelle" uniqKey="Apartis E" first="Emmanuelle" last="Apartis">Emmanuelle Apartis</name>
<name sortKey="Apartis, Emmanuelle" sort="Apartis, Emmanuelle" uniqKey="Apartis E" first="Emmanuelle" last="Apartis">Emmanuelle Apartis</name>
<name sortKey="Apartis, Emmanuelle" sort="Apartis, Emmanuelle" uniqKey="Apartis E" first="Emmanuelle" last="Apartis">Emmanuelle Apartis</name>
<name sortKey="Bardinet, Eric" sort="Bardinet, Eric" uniqKey="Bardinet E" first="Eric" last="Bardinet">Eric Bardinet</name>
<name sortKey="Bardinet, Eric" sort="Bardinet, Eric" uniqKey="Bardinet E" first="Eric" last="Bardinet">Eric Bardinet</name>
<name sortKey="Bardinet, Eric" sort="Bardinet, Eric" uniqKey="Bardinet E" first="Eric" last="Bardinet">Eric Bardinet</name>
<name sortKey="Bardinet, Eric" sort="Bardinet, Eric" uniqKey="Bardinet E" first="Eric" last="Bardinet">Eric Bardinet</name>
<name sortKey="Degos, Bertrand" sort="Degos, Bertrand" uniqKey="Degos B" first="Bertrand" last="Degos">Bertrand Degos</name>
<name sortKey="Degos, Bertrand" sort="Degos, Bertrand" uniqKey="Degos B" first="Bertrand" last="Degos">Bertrand Degos</name>
<name sortKey="Degos, Bertrand" sort="Degos, Bertrand" uniqKey="Degos B" first="Bertrand" last="Degos">Bertrand Degos</name>
<name sortKey="Degos, Bertrand" sort="Degos, Bertrand" uniqKey="Degos B" first="Bertrand" last="Degos">Bertrand Degos</name>
<name sortKey="Fernandez Vidal, Sara" sort="Fernandez Vidal, Sara" uniqKey="Fernandez Vidal S" first="Sara" last="Fernández-Vidal">Sara Fernández-Vidal</name>
<name sortKey="Fernandez Vidal, Sara" sort="Fernandez Vidal, Sara" uniqKey="Fernandez Vidal S" first="Sara" last="Fernández-Vidal">Sara Fernández-Vidal</name>
<name sortKey="Fernandez Vidal, Sara" sort="Fernandez Vidal, Sara" uniqKey="Fernandez Vidal S" first="Sara" last="Fernández-Vidal">Sara Fernández-Vidal</name>
<name sortKey="Fernandez Vidal, Sara" sort="Fernandez Vidal, Sara" uniqKey="Fernandez Vidal S" first="Sara" last="Fernández-Vidal">Sara Fernández-Vidal</name>
<name sortKey="Gallea, Cecile" sort="Gallea, Cecile" uniqKey="Gallea C" first="Cécile" last="Gallea">Cécile Gallea</name>
<name sortKey="Gallea, Cecile" sort="Gallea, Cecile" uniqKey="Gallea C" first="Cécile" last="Gallea">Cécile Gallea</name>
<name sortKey="Gallea, Cecile" sort="Gallea, Cecile" uniqKey="Gallea C" first="Cécile" last="Gallea">Cécile Gallea</name>
<name sortKey="Gallea, Cecile" sort="Gallea, Cecile" uniqKey="Gallea C" first="Cécile" last="Gallea">Cécile Gallea</name>
<name sortKey="Garcia Lorenzo, Daniel" sort="Garcia Lorenzo, Daniel" uniqKey="Garcia Lorenzo D" first="Daniel" last="García-Lorenzo">Daniel García-Lorenzo</name>
<name sortKey="Garcia Lorenzo, Daniel" sort="Garcia Lorenzo, Daniel" uniqKey="Garcia Lorenzo D" first="Daniel" last="García-Lorenzo">Daniel García-Lorenzo</name>
<name sortKey="Garcia Lorenzo, Daniel" sort="Garcia Lorenzo, Daniel" uniqKey="Garcia Lorenzo D" first="Daniel" last="García-Lorenzo">Daniel García-Lorenzo</name>
<name sortKey="Garcia Lorenzo, Daniel" sort="Garcia Lorenzo, Daniel" uniqKey="Garcia Lorenzo D" first="Daniel" last="García-Lorenzo">Daniel García-Lorenzo</name>
<name sortKey="Garcia Lorenzo, Daniel" sort="Garcia Lorenzo, Daniel" uniqKey="Garcia Lorenzo D" first="Daniel" last="García-Lorenzo">Daniel García-Lorenzo</name>
<name sortKey="Hubsch, Cecile" sort="Hubsch, Cecile" uniqKey="Hubsch C" first="Cecile" last="Hubsch">Cecile Hubsch</name>
<name sortKey="Hubsch, Cecile" sort="Hubsch, Cecile" uniqKey="Hubsch C" first="Cecile" last="Hubsch">Cecile Hubsch</name>
<name sortKey="Hubsch, Cecile" sort="Hubsch, Cecile" uniqKey="Hubsch C" first="Cecile" last="Hubsch">Cecile Hubsch</name>
<name sortKey="Hubsch, Cecile" sort="Hubsch, Cecile" uniqKey="Hubsch C" first="Cecile" last="Hubsch">Cecile Hubsch</name>
<name sortKey="Legrand, Andre Pierre" sort="Legrand, Andre Pierre" uniqKey="Legrand A" first="André-Pierre" last="Legrand">André-Pierre Legrand</name>
<name sortKey="Lehericy, Stephane" sort="Lehericy, Stephane" uniqKey="Lehericy S" first="Stéphane" last="Lehéricy">Stéphane Lehéricy</name>
<name sortKey="Lehericy, Stephane" sort="Lehericy, Stephane" uniqKey="Lehericy S" first="Stéphane" last="Lehéricy">Stéphane Lehéricy</name>
<name sortKey="Lehericy, Stephane" sort="Lehericy, Stephane" uniqKey="Lehericy S" first="Stéphane" last="Lehéricy">Stéphane Lehéricy</name>
<name sortKey="Lehericy, Stephane" sort="Lehericy, Stephane" uniqKey="Lehericy S" first="Stéphane" last="Lehéricy">Stéphane Lehéricy</name>
<name sortKey="Lehericy, Stephane" sort="Lehericy, Stephane" uniqKey="Lehericy S" first="Stéphane" last="Lehéricy">Stéphane Lehéricy</name>
<name sortKey="Marais, Lea" sort="Marais, Lea" uniqKey="Marais L" first="Lea" last="Marais">Lea Marais</name>
<name sortKey="Marais, Lea" sort="Marais, Lea" uniqKey="Marais L" first="Lea" last="Marais">Lea Marais</name>
<name sortKey="Marais, Lea" sort="Marais, Lea" uniqKey="Marais L" first="Lea" last="Marais">Lea Marais</name>
<name sortKey="Marais, Lea" sort="Marais, Lea" uniqKey="Marais L" first="Lea" last="Marais">Lea Marais</name>
<name sortKey="Marais, Lea" sort="Marais, Lea" uniqKey="Marais L" first="Lea" last="Marais">Lea Marais</name>
<name sortKey="Meunier, Sabine" sort="Meunier, Sabine" uniqKey="Meunier S" first="Sabine" last="Meunier">Sabine Meunier</name>
<name sortKey="Meunier, Sabine" sort="Meunier, Sabine" uniqKey="Meunier S" first="Sabine" last="Meunier">Sabine Meunier</name>
<name sortKey="Meunier, Sabine" sort="Meunier, Sabine" uniqKey="Meunier S" first="Sabine" last="Meunier">Sabine Meunier</name>
<name sortKey="Popa, Traian" sort="Popa, Traian" uniqKey="Popa T" first="Traian" last="Popa">Traian Popa</name>
<name sortKey="Popa, Traian" sort="Popa, Traian" uniqKey="Popa T" first="Traian" last="Popa">Traian Popa</name>
<name sortKey="Popa, Traian" sort="Popa, Traian" uniqKey="Popa T" first="Traian" last="Popa">Traian Popa</name>
<name sortKey="Popa, Traian" sort="Popa, Traian" uniqKey="Popa T" first="Traian" last="Popa">Traian Popa</name>
<name sortKey="Roze, Emmanuel" sort="Roze, Emmanuel" uniqKey="Roze E" first="Emmanuel" last="Roze">Emmanuel Roze</name>
<name sortKey="Roze, Emmanuel" sort="Roze, Emmanuel" uniqKey="Roze E" first="Emmanuel" last="Roze">Emmanuel Roze</name>
<name sortKey="Roze, Emmanuel" sort="Roze, Emmanuel" uniqKey="Roze E" first="Emmanuel" last="Roze">Emmanuel Roze</name>
<name sortKey="Roze, Emmanuel" sort="Roze, Emmanuel" uniqKey="Roze E" first="Emmanuel" last="Roze">Emmanuel Roze</name>
<name sortKey="Valabregue, Romain" sort="Valabregue, Romain" uniqKey="Valabregue R" first="Romain" last="Valabregue">Romain Valabregue</name>
<name sortKey="Valabregue, Romain" sort="Valabregue, Romain" uniqKey="Valabregue R" first="Romain" last="Valabregue">Romain Valabregue</name>
<name sortKey="Valabregue, Romain" sort="Valabregue, Romain" uniqKey="Valabregue R" first="Romain" last="Valabregue">Romain Valabregue</name>
<name sortKey="Valabregue, Romain" sort="Valabregue, Romain" uniqKey="Valabregue R" first="Romain" last="Valabregue">Romain Valabregue</name>
<name sortKey="Valabregue, Romain" sort="Valabregue, Romain" uniqKey="Valabregue R" first="Romain" last="Valabregue">Romain Valabregue</name>
<name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name>
<name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name>
<name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name>
<name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name>
</country>
</tree>
</affiliations>
</record>

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