La maladie de Parkinson en France (serveur d'exploration)

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Camptocormia as a clinical manifestation of polymyositis/systemic sclerosis overlap myositis associated with anti-Ku.

Identifieur interne : 000E79 ( Ncbi/Merge ); précédent : 000E78; suivant : 000E80

Camptocormia as a clinical manifestation of polymyositis/systemic sclerosis overlap myositis associated with anti-Ku.

Auteurs : Thierry Zenone [France] ; Nathalie Streichenberger ; Marie Puget

Source :

RBID : pubmed:22453528

English descriptors

Abstract

Camptocormia, an abnormal truncal flexion posture that occurs while walking or standing, is usually caused by various hypokinetic movement disorders, mainly Parkinson disease. We describe the case of a man with subacute onset of camptocormia. Quadriceps muscle biopsy showed significant rhabdomyolysis, few isolated inflammatory cells and mild expression of type I MHC in few fibers, a pattern usually found in immune-mediated necrotizing myopathies. Myositis was associated with Raynaud's phenomenon, mild sclerodactyly, and anti-Ku antibodies leading to the diagnosis of polymyositis/systemic sclerosis overlap myositis. The posture showed modest improvement in response to treatment.

DOI: 10.1007/s00296-012-2412-6
PubMed: 22453528

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pubmed:22453528

Le document en format XML

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