ParkinsonFranceV1, Ncbi, Merge, bibRecord, 000115

How patients with Parkinson's disease retrieve and manage cognitive event knowledge.

Identifieur interne : 000115 ( Ncbi/Merge ); précédent : 000114; suivant : 000116

How patients with Parkinson's disease retrieve and manage cognitive event knowledge.

Auteurs : T. Zalla [France] ; A. Sirigu ; B. Pillon ; B. Dubois ; Yves Agid [France] ; J. Grafman

Source :

Cortex; a journal devoted to the study of the nervous system and behavior [ 0010-9452 ] ; 2000.

RBID : pubmed:10815704

English descriptors

KwdEn :
- Adult, Aged, Cognition, Female, Humans, Knowledge, Male, Mental Recall, Middle Aged, Parkinson Disease (psychology), Psychological Tests, Reference Values.
MESH :
- psychology : Parkinson Disease.
- Adult, Aged, Cognition, Female, Humans, Knowledge, Male, Mental Recall, Middle Aged, Psychological Tests, Reference Values.

Abstract

Several studies have pointed out that basal ganglia are involved in adaptive control of action at both motor and cognitive level. This study aimed to investigate how basal ganglia retrieve and manage script event knowledge required in planning behavior. Script event knowledge was investigated in patients with Parkinson's Disease using three kinds of activity that differed in familiarity. Unlike patients with prefrontal lesions, patients with Parkinson's Disease were able to order events in a typical sequence and obeyed the boundaries and hierarchies between events. In contrast, patients with Parkinson's Disease were impaired in evaluating how important each script event was within the context of goal-oriented planning activity. Our findings indicate that the prefrontal cortex and the basal ganglia are differentially involved in planning. The role of the basal ganglia might consist in providing a feedback about the goodness of each action while building up meaningful sequences of events during learning.

PubMed: 10815704

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to stream PubMed, to step Checkpoint: 001289

Links to Exploration step

pubmed:10815704

Le document en format XML

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<front><div type="abstract" xml:lang="en">Several studies have pointed out that basal ganglia are involved in adaptive control of action at both motor and cognitive level. This study aimed to investigate how basal ganglia retrieve and manage script event knowledge required in planning behavior. Script event knowledge was investigated in patients with Parkinson's Disease using three kinds of activity that differed in familiarity. Unlike patients with prefrontal lesions, patients with Parkinson's Disease were able to order events in a typical sequence and obeyed the boundaries and hierarchies between events. In contrast, patients with Parkinson's Disease were impaired in evaluating how important each script event was within the context of goal-oriented planning activity. Our findings indicate that the prefrontal cortex and the basal ganglia are differentially involved in planning. The role of the basal ganglia might consist in providing a feedback about the goodness of each action while building up meaningful sequences of events during learning.</div>
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	La maladie de Parkinson en France (serveur d'exploration)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

La maladie de Parkinson en France (serveur d'exploration)

How patients with Parkinson's disease retrieve and manage cognitive event knowledge.

How patients with Parkinson's disease retrieve and manage cognitive event knowledge.

Source :

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Links to Exploration step

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki