Peripheral neuropathy and parkinsonism: a large clinical and pathogenic spectrum.
Identifieur interne : 001626 ( Ncbi/Curation ); précédent : 001625; suivant : 001627Peripheral neuropathy and parkinsonism: a large clinical and pathogenic spectrum.
Auteurs : Anne Vital [France] ; Sebastien Lepreux ; Claude VitalSource :
- Journal of the peripheral nervous system : JPNS [ 1529-8027 ] ; 2014.
English descriptors
- KwdEn :
- MESH :
- complications : Parkinson Disease.
- etiology : Peripheral Nervous System Diseases.
- Humans.
Abstract
Peripheral neuropathy (PN) has been reported in idiopathic and hereditary forms of parkinsonism, but the pathogenic mechanisms are unclear and likely heterogeneous. Levodopa-induced vitamin B12 deficiency has been discussed as a causal factor of PN in idiopathic Parkinson's disease, but peripheral nervous system involvement might also be a consequence of the underlying neurodegenerative process. Occurrence of PN with parkinsonism has been associated with a panel of mitochondrial cytopathies, more frequently related to a nuclear gene defect and mainly polymerase gamma (POLG1) gene. Parkin (PARK2) gene mutations are responsible for juvenile parkinsonism, and possible peripheral nervous system involvement has been reported. Rarely, an association of parkinsonism with PN may be encountered in other neurodegenerative diseases such as fragile X-associated tremor and ataxia syndrome related to premutation CGG repeat expansion in the fragile X mental retardation (FMR1) gene, Machado-Joseph disease related to an abnormal CAG repeat expansion in ataxin-3 (ATXN3) gene, Kufor-Rakeb syndrome caused by mutations in ATP13A2 gene, or in hereditary systemic disorders such as Gaucher disease due to mutations in the β-glucocerebrosidase (GBA) gene and Chediak-Higashi syndrome due to LYST gene mutations. This article reviews conditions in which PN may coexist with parkinsonism.
DOI: 10.1111/jns.12099
PubMed: 25582874
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000459
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :000450
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000450
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :001626
Links to Exploration step
pubmed:25582874Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Peripheral neuropathy and parkinsonism: a large clinical and pathogenic spectrum.</title><author><name sortKey="Vital, Anne" sort="Vital, Anne" uniqKey="Vital A" first="Anne" last="Vital">Anne Vital</name><affiliation wicri:level="3"><nlm:affiliation>University of Bordeaux, Bordeaux, France; CNRS, Institut des Maladies Neurodégénératives, Bordeaux, France; Department of Pathology, Bordeaux University Hospital, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University of Bordeaux, Bordeaux, France; CNRS, Institut des Maladies Neurodégénératives, Bordeaux, France; Department of Pathology, Bordeaux University Hospital, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Lepreux, Sebastien" sort="Lepreux, Sebastien" uniqKey="Lepreux S" first="Sebastien" last="Lepreux">Sebastien Lepreux</name></author><author><name sortKey="Vital, Claude" sort="Vital, Claude" uniqKey="Vital C" first="Claude" last="Vital">Claude Vital</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:25582874</idno><idno type="pmid">25582874</idno><idno type="doi">10.1111/jns.12099</idno><idno type="wicri:Area/PubMed/Corpus">000459</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000459</idno><idno type="wicri:Area/PubMed/Curation">000450</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000450</idno><idno type="wicri:Area/PubMed/Checkpoint">000450</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000450</idno><idno type="wicri:Area/Ncbi/Merge">001626</idno><idno type="wicri:Area/Ncbi/Curation">001626</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Peripheral neuropathy and parkinsonism: a large clinical and pathogenic spectrum.</title><author><name sortKey="Vital, Anne" sort="Vital, Anne" uniqKey="Vital A" first="Anne" last="Vital">Anne Vital</name><affiliation wicri:level="3"><nlm:affiliation>University of Bordeaux, Bordeaux, France; CNRS, Institut des Maladies Neurodégénératives, Bordeaux, France; Department of Pathology, Bordeaux University Hospital, Bordeaux, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>University of Bordeaux, Bordeaux, France; CNRS, Institut des Maladies Neurodégénératives, Bordeaux, France; Department of Pathology, Bordeaux University Hospital, Bordeaux</wicri:regionArea><placeName><region type="region">Nouvelle-Aquitaine</region><region type="old region">Aquitaine</region><settlement type="city">Bordeaux</settlement></placeName></affiliation></author><author><name sortKey="Lepreux, Sebastien" sort="Lepreux, Sebastien" uniqKey="Lepreux S" first="Sebastien" last="Lepreux">Sebastien Lepreux</name></author><author><name sortKey="Vital, Claude" sort="Vital, Claude" uniqKey="Vital C" first="Claude" last="Vital">Claude Vital</name></author></analytic><series><title level="j">Journal of the peripheral nervous system : JPNS</title><idno type="eISSN">1529-8027</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Humans</term><term>Parkinson Disease (complications)</term><term>Peripheral Nervous System Diseases (etiology)</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Peripheral Nervous System Diseases</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Peripheral neuropathy (PN) has been reported in idiopathic and hereditary forms of parkinsonism, but the pathogenic mechanisms are unclear and likely heterogeneous. Levodopa-induced vitamin B12 deficiency has been discussed as a causal factor of PN in idiopathic Parkinson's disease, but peripheral nervous system involvement might also be a consequence of the underlying neurodegenerative process. Occurrence of PN with parkinsonism has been associated with a panel of mitochondrial cytopathies, more frequently related to a nuclear gene defect and mainly polymerase gamma (POLG1) gene. Parkin (PARK2) gene mutations are responsible for juvenile parkinsonism, and possible peripheral nervous system involvement has been reported. Rarely, an association of parkinsonism with PN may be encountered in other neurodegenerative diseases such as fragile X-associated tremor and ataxia syndrome related to premutation CGG repeat expansion in the fragile X mental retardation (FMR1) gene, Machado-Joseph disease related to an abnormal CAG repeat expansion in ataxin-3 (ATXN3) gene, Kufor-Rakeb syndrome caused by mutations in ATP13A2 gene, or in hereditary systemic disorders such as Gaucher disease due to mutations in the β-glucocerebrosidase (GBA) gene and Chediak-Higashi syndrome due to LYST gene mutations. This article reviews conditions in which PN may coexist with parkinsonism.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001626 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 001626 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonFranceV1
|flux= Ncbi
|étape= Curation
|type= RBID
|clé= pubmed:25582874
|texte= Peripheral neuropathy and parkinsonism: a large clinical and pathogenic spectrum.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:25582874" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \
| NlmPubMed2Wicri -a ParkinsonFranceV1
| This area was generated with Dilib version V0.6.29. |  |