Tesofensine (NS 2330), a monoamine reuptake inhibitor, in patients with advanced Parkinson disease and motor fluctuations: the ADVANS Study.
Identifieur interne : 000858 ( Ncbi/Curation ); précédent : 000857; suivant : 000859Tesofensine (NS 2330), a monoamine reuptake inhibitor, in patients with advanced Parkinson disease and motor fluctuations: the ADVANS Study.
Auteurs : Olivier Rascol [France] ; Werner Poewe [Autriche] ; Andrew Lees ; Marina Aristin ; Laurence Salin ; Nolwenn Juhel ; Lisa Waldhauser ; Thomas SchindlerSource :
- Archives of neurology [ 1538-3687 ] ; 2008.
English descriptors
- KwdEn :
- Activities of Daily Living, Adult, Aged, Aged, 80 and over, Biogenic Monoamines (agonists), Bridged Bicyclo Compounds, Heterocyclic (administration & dosage), Bridged Bicyclo Compounds, Heterocyclic (adverse effects), Bridged Bicyclo Compounds, Heterocyclic (blood), Disease Progression, Dose-Response Relationship, Drug, Double-Blind Method, Female, Gastrointestinal Diseases (chemically induced), Humans, Male, Mental Disorders (chemically induced), Middle Aged, Neurotransmitter Uptake Inhibitors (administration & dosage), Neurotransmitter Uptake Inhibitors (adverse effects), Neurotransmitter Uptake Inhibitors (blood), Parkinson Disease (drug therapy), Pilot Projects, Placebos, Treatment Outcome.
- MESH :
- chemical , administration & dosage : Bridged Bicyclo Compounds, Heterocyclic, Neurotransmitter Uptake Inhibitors.
- chemical , adverse effects : Bridged Bicyclo Compounds, Heterocyclic, Neurotransmitter Uptake Inhibitors.
- chemical , agonists : Biogenic Monoamines.
- chemical , blood : Bridged Bicyclo Compounds, Heterocyclic, Neurotransmitter Uptake Inhibitors.
- chemically induced : Gastrointestinal Diseases, Mental Disorders.
- drug therapy : Parkinson Disease.
- Activities of Daily Living, Adult, Aged, Aged, 80 and over, Disease Progression, Dose-Response Relationship, Drug, Double-Blind Method, Female, Humans, Male, Middle Aged, Pilot Projects, Placebos, Treatment Outcome.
Abstract
To assess the safety and efficacy of tesofensine, a triple monoamine reuptake inhibitor, in patients with advanced Parkinson disease (PD).
DOI: 10.1001/archneur.65.5.577
PubMed: 18474731
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pubmed:18474731Le document en format XML
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