Prevention and therapeutic strategies for levodopa-induced dyskinesias in Parkinson's disease.
Identifieur interne : 000132 ( Ncbi/Curation ); précédent : 000131; suivant : 000133Prevention and therapeutic strategies for levodopa-induced dyskinesias in Parkinson's disease.
Auteurs : J J Ferreira [France] ; O. RascolSource :
- Current opinion in neurology [ 1350-7540 ] ; 2000.
English descriptors
- KwdEn :
- MESH :
- chemical , adverse effects : Antiparkinson Agents, Levodopa.
- drug therapy : Movement Disorders, Parkinson Disease.
- prevention & control : Movement Disorders.
- surgery : Movement Disorders.
- therapy : Movement Disorders.
- Humans.
Abstract
Levodopa-induced dyskinesias represent a major shortcoming of Parkinson's disease management, and its pharmacological treatment is generally unsatisfactory. However, the conclusive demonstration of the benefits associated with early prescription of a dopamine agonist, the antidyskinetic properties of 'old' antiparkinsonian compounds such as amantadine, and the striking results of functional stereotatic neurosurgery are extremely important advances for the treatment of levodopa-induced dyskinesias.
PubMed: 10970061
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