La maladie de Parkinson en France (serveur d'exploration)

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Hallucinations in schizophrenia and Parkinson’s disease: an analysis of sensory modalities involved and the repercussion on patients

Identifieur interne : 001B69 ( Ncbi/Checkpoint ); précédent : 001B68; suivant : 001B70

Hallucinations in schizophrenia and Parkinson’s disease: an analysis of sensory modalities involved and the repercussion on patients

Auteurs : P. M. Llorca [France] ; B. Pereira [France] ; R. Jardri [France] ; I. Chereau-Boudet [France] ; G. Brousse [France] ; D. Misdrahi [France] ; G. Fénelon [France] ; A.-M. Tronche [France] ; R. Schwan [France] ; C. Lançon [France] ; A. Marques [France] ; M. Ulla [France] ; P. Derost [France] ; B. Debilly [France] ; F. Durif [France] ; I. De Chazeron [France]

Source :

RBID : PMC:5131286

Abstract

Hallucinations have been described in various clinical populations, but they are neither disorder nor disease specific. In schizophrenia patients, hallucinations are hallmark symptoms and auditory ones are described as the more frequent. In Parkinson’s disease, the descriptions of hallucination modalities are sparse, but the hallucinations do tend to have less negative consequences. Our study aims to explore the phenomenology of hallucinations in both hallucinating schizophrenia patients and Parkinson’s disease patients using the Psycho-Sensory hAllucinations Scale (PSAS). The main objective is to describe the phenomena of these clinical symptoms in those two specific populations. Each hallucinatory sensory modality significantly differed between Parkinson’s disease and schizophrenia patients. Auditory, olfactory/gustatory and cœnesthetic hallucinations were more frequent in schizophrenia than visual hallucinations. The guardian angel item, usually not explored in schizophrenia, was described by 46% of these patients. The combination of auditory and visual hallucinations was the most frequent for both Parkinson’s disease and schizophrenia. The repercussion index summing characteristics of each hallucination (frequency, duration, negative aspects, conviction, impact, control and sound intensity) was always higher for schizophrenia. A broader view including widespread characteristics and interdisciplinary works must be encouraged to better understand the complexity of the process involved in hallucinations.


Url:
DOI: 10.1038/srep38152
PubMed: 27905557
PubMed Central: 5131286


Affiliations:


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PMC:5131286

Le document en format XML

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<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<name sortKey="Ulla, M" sort="Ulla, M" uniqKey="Ulla M" first="M." last="Ulla">M. Ulla</name>
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<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<title xml:lang="en" level="a" type="main">Hallucinations in schizophrenia and Parkinson’s disease: an analysis of sensory modalities involved and the repercussion on patients</title>
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<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<name sortKey="Jardri, R" sort="Jardri, R" uniqKey="Jardri R" first="R." last="Jardri">R. Jardri</name>
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<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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,
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<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<name sortKey="Chereau Boudet, I" sort="Chereau Boudet, I" uniqKey="Chereau Boudet I" first="I." last="Chereau-Boudet">I. Chereau-Boudet</name>
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<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<name sortKey="Brousse, G" sort="Brousse, G" uniqKey="Brousse G" first="G." last="Brousse">G. Brousse</name>
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, F-63003,
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<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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, F-63001,
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</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<name sortKey="Misdrahi, D" sort="Misdrahi, D" uniqKey="Misdrahi D" first="D." last="Misdrahi">D. Misdrahi</name>
<affiliation wicri:level="1">
<nlm:aff id="a6">
<institution>Pôle de Psychiatrie Adulte, CH Charles Perrens; cs 81285</institution>
, 33000 Bordeaux cedex,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<institution>CNRS UMR 5287-INCIA-“Neuroimagerie et cognition humaine”, Université Bordeaux 2</institution>
, Bordeaux,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<name sortKey="Fenelon, G" sort="Fenelon, G" uniqKey="Fenelon G" first="G." last="Fénelon">G. Fénelon</name>
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<nlm:aff id="a8">
<institution>AP-HP, Groupe Hospitalier Henri-Mondor, Service de neurologie</institution>
, Créteil,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="a9">
<institution>INSERM U955, Equipe 1, Institut Mondor de Recherche Biomédicale</institution>
, Créteil,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="a10">
<institution>Ecole Normale Supérieure, Institut d’Etudes Cognitives</institution>
, Paris,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
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<name sortKey="Tronche, A M" sort="Tronche, A M" uniqKey="Tronche A" first="A.-M." last="Tronche">A.-M. Tronche</name>
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<institution>CHU Clermont-Ferrand, Psychiatry B, Clermont-Ferrand</institution>
, F-63003,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Schwan, R" sort="Schwan, R" uniqKey="Schwan R" first="R." last="Schwan">R. Schwan</name>
<affiliation wicri:level="1">
<nlm:aff id="a11">
<institution>Pôle hospitalier universitaire de psychiatrie du Grand Nancy, CPN Chef de Service Maison des Addictions</institution>
, CHU de Nancy,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Lancon, C" sort="Lancon, C" uniqKey="Lancon C" first="C." last="Lançon">C. Lançon</name>
<affiliation wicri:level="1">
<nlm:aff id="a12">
<institution>Department of Psychiatry/Department of Addiction, Sainte-Marguerite University Hospital</institution>
, 13009 Marseille,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="a13">
<institution>EA 3279-Public Health, Chronic Disease, and Quality of Life Research Unit, Aix-Marseille University</institution>
, 13005 Marseille,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Marques, A" sort="Marques, A" uniqKey="Marques A" first="A." last="Marques">A. Marques</name>
<affiliation wicri:level="1">
<nlm:aff id="a2">
<institution>Univ Clermont 1, UFR Medecine, EA7280, Clermont-Ferrand</institution>
, F-63001,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="a14">
<institution>CHU Clermont-Ferrand, Neurology A, Clermont-Ferrand</institution>
, F-63003,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Ulla, M" sort="Ulla, M" uniqKey="Ulla M" first="M." last="Ulla">M. Ulla</name>
<affiliation wicri:level="1">
<nlm:aff id="a2">
<institution>Univ Clermont 1, UFR Medecine, EA7280, Clermont-Ferrand</institution>
, F-63001,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="a14">
<institution>CHU Clermont-Ferrand, Neurology A, Clermont-Ferrand</institution>
, F-63003,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Derost, P" sort="Derost, P" uniqKey="Derost P" first="P." last="Derost">P. Derost</name>
<affiliation wicri:level="1">
<nlm:aff id="a2">
<institution>Univ Clermont 1, UFR Medecine, EA7280, Clermont-Ferrand</institution>
, F-63001,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="a14">
<institution>CHU Clermont-Ferrand, Neurology A, Clermont-Ferrand</institution>
, F-63003,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Debilly, B" sort="Debilly, B" uniqKey="Debilly B" first="B." last="Debilly">B. Debilly</name>
<affiliation wicri:level="1">
<nlm:aff id="a2">
<institution>Univ Clermont 1, UFR Medecine, EA7280, Clermont-Ferrand</institution>
, F-63001,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="a14">
<institution>CHU Clermont-Ferrand, Neurology A, Clermont-Ferrand</institution>
, F-63003,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Durif, F" sort="Durif, F" uniqKey="Durif F" first="F." last="Durif">F. Durif</name>
<affiliation wicri:level="1">
<nlm:aff id="a2">
<institution>Univ Clermont 1, UFR Medecine, EA7280, Clermont-Ferrand</institution>
, F-63001,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="a14">
<institution>CHU Clermont-Ferrand, Neurology A, Clermont-Ferrand</institution>
, F-63003,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="De Chazeron, I" sort="De Chazeron, I" uniqKey="De Chazeron I" first="I." last="De Chazeron">I. De Chazeron</name>
<affiliation wicri:level="1">
<nlm:aff id="a1">
<institution>CHU Clermont-Ferrand, Psychiatry B, Clermont-Ferrand</institution>
, F-63003,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
<affiliation wicri:level="1">
<nlm:aff id="a2">
<institution>Univ Clermont 1, UFR Medecine, EA7280, Clermont-Ferrand</institution>
, F-63001,
<country>France</country>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea># see nlm:aff country strict</wicri:regionArea>
</affiliation>
</author>
</analytic>
<series>
<title level="j">Scientific Reports</title>
<idno type="eISSN">2045-2322</idno>
<imprint>
<date when="2016">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc>
<textClass></textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">
<p>Hallucinations have been described in various clinical populations, but they are neither disorder nor disease specific. In schizophrenia patients, hallucinations are hallmark symptoms and auditory ones are described as the more frequent. In Parkinson’s disease, the descriptions of hallucination modalities are sparse, but the hallucinations do tend to have less negative consequences. Our study aims to explore the phenomenology of hallucinations in both hallucinating schizophrenia patients and Parkinson’s disease patients using the
<italic>Psycho-Sensory hAllucinations Scale</italic>
(PSAS). The main objective is to describe the phenomena of these clinical symptoms in those two specific populations. Each hallucinatory sensory modality significantly differed between Parkinson’s disease and schizophrenia patients. Auditory, olfactory/gustatory and cœnesthetic hallucinations were more frequent in schizophrenia than visual hallucinations. The guardian angel item, usually not explored in schizophrenia, was described by 46% of these patients. The combination of auditory and visual hallucinations was the most frequent for both Parkinson’s disease and schizophrenia. The repercussion index summing characteristics of each hallucination (frequency, duration, negative aspects, conviction, impact, control and sound intensity) was always higher for schizophrenia. A broader view including widespread characteristics and interdisciplinary works must be encouraged to better understand the complexity of the process involved in hallucinations.</p>
</div>
</front>
<back>
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<name sortKey="Jardri, R" uniqKey="Jardri R">R. Jardri</name>
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<name sortKey="Mccarthy Jones, S" uniqKey="Mccarthy Jones S">S. McCarthy-Jones</name>
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<author>
<name sortKey="Longden, E" uniqKey="Longden E">E. Longden</name>
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<analytic>
<author>
<name sortKey="Hoehn, M M" uniqKey="Hoehn M">M. M. Hoehn</name>
</author>
<author>
<name sortKey="Yahr, M D" uniqKey="Yahr M">M. D. Yahr</name>
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</analytic>
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</div1>
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<country>
<li>France</li>
</country>
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<name sortKey="Brousse, G" sort="Brousse, G" uniqKey="Brousse G" first="G." last="Brousse">G. Brousse</name>
<name sortKey="Chereau Boudet, I" sort="Chereau Boudet, I" uniqKey="Chereau Boudet I" first="I." last="Chereau-Boudet">I. Chereau-Boudet</name>
<name sortKey="Chereau Boudet, I" sort="Chereau Boudet, I" uniqKey="Chereau Boudet I" first="I." last="Chereau-Boudet">I. Chereau-Boudet</name>
<name sortKey="De Chazeron, I" sort="De Chazeron, I" uniqKey="De Chazeron I" first="I." last="De Chazeron">I. De Chazeron</name>
<name sortKey="De Chazeron, I" sort="De Chazeron, I" uniqKey="De Chazeron I" first="I." last="De Chazeron">I. De Chazeron</name>
<name sortKey="Debilly, B" sort="Debilly, B" uniqKey="Debilly B" first="B." last="Debilly">B. Debilly</name>
<name sortKey="Debilly, B" sort="Debilly, B" uniqKey="Debilly B" first="B." last="Debilly">B. Debilly</name>
<name sortKey="Derost, P" sort="Derost, P" uniqKey="Derost P" first="P." last="Derost">P. Derost</name>
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<name sortKey="Durif, F" sort="Durif, F" uniqKey="Durif F" first="F." last="Durif">F. Durif</name>
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<name sortKey="Fenelon, G" sort="Fenelon, G" uniqKey="Fenelon G" first="G." last="Fénelon">G. Fénelon</name>
<name sortKey="Fenelon, G" sort="Fenelon, G" uniqKey="Fenelon G" first="G." last="Fénelon">G. Fénelon</name>
<name sortKey="Fenelon, G" sort="Fenelon, G" uniqKey="Fenelon G" first="G." last="Fénelon">G. Fénelon</name>
<name sortKey="Jardri, R" sort="Jardri, R" uniqKey="Jardri R" first="R." last="Jardri">R. Jardri</name>
<name sortKey="Jardri, R" sort="Jardri, R" uniqKey="Jardri R" first="R." last="Jardri">R. Jardri</name>
<name sortKey="Lancon, C" sort="Lancon, C" uniqKey="Lancon C" first="C." last="Lançon">C. Lançon</name>
<name sortKey="Lancon, C" sort="Lancon, C" uniqKey="Lancon C" first="C." last="Lançon">C. Lançon</name>
<name sortKey="Llorca, P M" sort="Llorca, P M" uniqKey="Llorca P" first="P. M." last="Llorca">P. M. Llorca</name>
<name sortKey="Marques, A" sort="Marques, A" uniqKey="Marques A" first="A." last="Marques">A. Marques</name>
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<name sortKey="Misdrahi, D" sort="Misdrahi, D" uniqKey="Misdrahi D" first="D." last="Misdrahi">D. Misdrahi</name>
<name sortKey="Misdrahi, D" sort="Misdrahi, D" uniqKey="Misdrahi D" first="D." last="Misdrahi">D. Misdrahi</name>
<name sortKey="Pereira, B" sort="Pereira, B" uniqKey="Pereira B" first="B." last="Pereira">B. Pereira</name>
<name sortKey="Schwan, R" sort="Schwan, R" uniqKey="Schwan R" first="R." last="Schwan">R. Schwan</name>
<name sortKey="Tronche, A M" sort="Tronche, A M" uniqKey="Tronche A" first="A.-M." last="Tronche">A.-M. Tronche</name>
<name sortKey="Ulla, M" sort="Ulla, M" uniqKey="Ulla M" first="M." last="Ulla">M. Ulla</name>
<name sortKey="Ulla, M" sort="Ulla, M" uniqKey="Ulla M" first="M." last="Ulla">M. Ulla</name>
</country>
</tree>
</affiliations>
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