STN-DBS frequency effects on freezing of gait in advanced Parkinson disease.
Identifieur interne : 000847 ( Ncbi/Checkpoint ); précédent : 000846; suivant : 000848STN-DBS frequency effects on freezing of gait in advanced Parkinson disease.
Auteurs : C. Moreau [France] ; L. Defebvre ; A. Destée ; S. Bleuse ; F. Clement ; J L Blatt ; P. Krystkowiak ; D. DevosSource :
- Neurology [ 1526-632X ] ; 2008.
English descriptors
- KwdEn :
- Accidental Falls (prevention & control), Cognition Disorders (etiology), Deep Brain Stimulation (adverse effects), Deep Brain Stimulation (methods), Follow-Up Studies, Gait, Humans, Muscle Rigidity (etiology), Muscle Rigidity (prevention & control), Parkinson Disease (complications), Parkinson Disease (therapy), Pedunculopontine Tegmental Nucleus (physiopathology), Pedunculopontine Tegmental Nucleus (surgery), Subthalamic Nucleus (physiopathology).
- MESH :
- adverse effects : Deep Brain Stimulation.
- complications : Parkinson Disease.
- etiology : Cognition Disorders, Muscle Rigidity.
- methods : Deep Brain Stimulation.
- physiopathology : Pedunculopontine Tegmental Nucleus, Subthalamic Nucleus.
- prevention & control : Accidental Falls, Muscle Rigidity.
- surgery : Pedunculopontine Tegmental Nucleus.
- therapy : Parkinson Disease.
- Follow-Up Studies, Gait, Humans.
Abstract
Severe gait disturbances and freezing episodes (frequently resistant to optimal dopaminergic treatment) often appear in advanced Parkinson disease (PD). Even several years after initiation, high-frequency subthalamic nucleus deep brain stimulation (STN-DBS) is still very effective for controlling segmental symptoms. However, there are no long-term data on the management of gait disorders and freezing in STN-DBS.
DOI: 10.1212/01.wnl.0000303972.16279.46
PubMed: 18420482
Affiliations:
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pubmed:18420482Le document en format XML
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<front><div type="abstract" xml:lang="en">Severe gait disturbances and freezing episodes (frequently resistant to optimal dopaminergic treatment) often appear in advanced Parkinson disease (PD). Even several years after initiation, high-frequency subthalamic nucleus deep brain stimulation (STN-DBS) is still very effective for controlling segmental symptoms. However, there are no long-term data on the management of gait disorders and freezing in STN-DBS.</div>
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