Executive function differences in multiple system atrophy and Parkinson's disease.
Identifieur interne : 000313 ( Ncbi/Checkpoint ); précédent : 000312; suivant : 000314Executive function differences in multiple system atrophy and Parkinson's disease.
Auteurs : Kathy Dujardin [France] ; Luc Defebvre [France] ; Pierre Krystkowiak ; Jean François Degreef ; Alain Destée [France]Source :
- Parkinsonism & related disorders [ 1353-8020 ] ; 2003.
English descriptors
- KwdEn :
- Adult, Age of Onset, Aged, Antiparkinson Agents (therapeutic use), Color Perception, Disease Progression, Female, Humans, Levodopa (therapeutic use), Male, Memory (physiology), Middle Aged, Multiple System Atrophy (drug therapy), Multiple System Atrophy (physiopathology), Neuropsychological Tests, Parkinson Disease (drug therapy), Parkinson Disease (physiopathology), Psychomotor Performance (physiology), Verbal Behavior.
- MESH :
- chemical , therapeutic use : Antiparkinson Agents, Levodopa.
- drug therapy : Multiple System Atrophy, Parkinson Disease.
- physiology : Memory, Psychomotor Performance.
- physiopathology : Multiple System Atrophy, Parkinson Disease.
- Adult, Age of Onset, Aged, Color Perception, Disease Progression, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Verbal Behavior.
Abstract
The aim of the present study was to assess executive function in patients with multiple system atrophy (MSA) and Parkinson's disease (PD) looking for specific differences and considering motor disability and disease duration. Performance of 11 MSA patients was compared to that of 12 healthy controls and two groups of 12 PD patients, one matched with respect to the severity of motor symptoms and the other with respect to disease duration. Compared to healthy controls, MSA and PD patients both presented executive dysfunction but, in MSA, the impairment was more severe and diffuse. This study suggests that despite the evidence of some differences in executive function in MSA and PD, the contribution of standard neuropsychological examination to the differential diagnosis of both syndromes remains still limited.
PubMed: 12618055
Affiliations:
- France
- Hauts-de-France, Nord-Pas-de-Calais
- Lille
- Université Lille 2, Université Lille Nord de France
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- to stream PubMed, to step Checkpoint: 001078
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Links to Exploration step
pubmed:12618055Le document en format XML
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<front><div type="abstract" xml:lang="en">The aim of the present study was to assess executive function in patients with multiple system atrophy (MSA) and Parkinson's disease (PD) looking for specific differences and considering motor disability and disease duration. Performance of 11 MSA patients was compared to that of 12 healthy controls and two groups of 12 PD patients, one matched with respect to the severity of motor symptoms and the other with respect to disease duration. Compared to healthy controls, MSA and PD patients both presented executive dysfunction but, in MSA, the impairment was more severe and diffuse. This study suggests that despite the evidence of some differences in executive function in MSA and PD, the contribution of standard neuropsychological examination to the differential diagnosis of both syndromes remains still limited.</div>
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