Dopaminergic function and dopamine transporter binding assessed with positron emission tomography in Parkinson disease.
Identifieur interne : 000233 ( Ncbi/Checkpoint ); précédent : 000232; suivant : 000234Dopaminergic function and dopamine transporter binding assessed with positron emission tomography in Parkinson disease.
Auteurs : Maria-Joao Ribeiro [France] ; Marie Vidailhet ; Christian Loc'H ; Corinne Dupel ; Jean Paul Nguyen ; Michel Ponchant ; Frédéric Dollé ; Marc Peschanski ; Philippe Hantraye ; Pierre Cesaro ; Yves Samson ; Philippe RemySource :
- Archives of neurology [ 0003-9942 ] ; 2002.
English descriptors
- KwdEn :
- Aged, Case-Control Studies, Corpus Striatum (metabolism), Dopamine (metabolism), Dopamine Plasma Membrane Transport Proteins, Female, Humans, Male, Membrane Glycoproteins, Membrane Transport Proteins (metabolism), Middle Aged, Nerve Tissue Proteins (metabolism), Parkinson Disease (diagnostic imaging), Parkinson Disease (metabolism), Tomography, Emission-Computed.
- MESH :
- chemical , metabolism : Dopamine, Membrane Transport Proteins, Nerve Tissue Proteins.
- diagnostic imaging : Parkinson Disease.
- metabolism : Corpus Striatum, Parkinson Disease.
- Aged, Case-Control Studies, Dopamine Plasma Membrane Transport Proteins, Female, Humans, Male, Membrane Glycoproteins, Middle Aged, Tomography, Emission-Computed.
Abstract
Measuring progression of Parkinson disease (PD) using positron emission tomography may help demonstrate the efficacy of neuroprotective treatments. To date, (18)F-dopa has been the gold standard to measure presynaptic dopaminergic function in PD, but this tracer might overestimate the rate of neuronal death in PD because its uptake also depends on dopamine turnover rather than exclusively on the density of dopaminergic terminals in the striatum. The latter might be assessed using newly developed ligands of the membrane dopamine transporter.
PubMed: 11939892
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 001197
- to stream PubMed, to step Curation: 001156
- to stream PubMed, to step Checkpoint: 001156
- to stream Ncbi, to step Merge: 000233
- to stream Ncbi, to step Curation: 000233
Links to Exploration step
pubmed:11939892Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Dopaminergic function and dopamine transporter binding assessed with positron emission tomography in Parkinson disease.</title><author><name sortKey="Ribeiro, Maria Joao" sort="Ribeiro, Maria Joao" uniqKey="Ribeiro M" first="Maria-Joao" last="Ribeiro">Maria-Joao Ribeiro</name><affiliation wicri:level="1"><nlm:affiliation>URA CEA-CNRS 2210, Service Hospitalier Frédéric Joliot, 4, place du Général Leclerc, 91401 Orsay, CEDEX, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>URA CEA-CNRS 2210, Service Hospitalier Frédéric Joliot, 4, place du Général Leclerc, 91401 Orsay, CEDEX</wicri:regionArea><wicri:noRegion>CEDEX</wicri:noRegion><wicri:noRegion>CEDEX</wicri:noRegion></affiliation></author><author><name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name></author><author><name sortKey="Loc H, Christian" sort="Loc H, Christian" uniqKey="Loc H C" first="Christian" last="Loc'H">Christian Loc'H</name></author><author><name sortKey="Dupel, Corinne" sort="Dupel, Corinne" uniqKey="Dupel C" first="Corinne" last="Dupel">Corinne Dupel</name></author><author><name sortKey="Nguyen, Jean Paul" sort="Nguyen, Jean Paul" uniqKey="Nguyen J" first="Jean Paul" last="Nguyen">Jean Paul Nguyen</name></author><author><name sortKey="Ponchant, Michel" sort="Ponchant, Michel" uniqKey="Ponchant M" first="Michel" last="Ponchant">Michel Ponchant</name></author><author><name sortKey="Dolle, Frederic" sort="Dolle, Frederic" uniqKey="Dolle F" first="Frédéric" last="Dollé">Frédéric Dollé</name></author><author><name sortKey="Peschanski, Marc" sort="Peschanski, Marc" uniqKey="Peschanski M" first="Marc" last="Peschanski">Marc Peschanski</name></author><author><name sortKey="Hantraye, Philippe" sort="Hantraye, Philippe" uniqKey="Hantraye P" first="Philippe" last="Hantraye">Philippe Hantraye</name></author><author><name sortKey="Cesaro, Pierre" sort="Cesaro, Pierre" uniqKey="Cesaro P" first="Pierre" last="Cesaro">Pierre Cesaro</name></author><author><name sortKey="Samson, Yves" sort="Samson, Yves" uniqKey="Samson Y" first="Yves" last="Samson">Yves Samson</name></author><author><name sortKey="Remy, Philippe" sort="Remy, Philippe" uniqKey="Remy P" first="Philippe" last="Remy">Philippe Remy</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2002">2002</date><idno type="RBID">pubmed:11939892</idno><idno type="pmid">11939892</idno><idno type="wicri:Area/PubMed/Corpus">001197</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001197</idno><idno type="wicri:Area/PubMed/Curation">001156</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001156</idno><idno type="wicri:Area/PubMed/Checkpoint">001156</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001156</idno><idno type="wicri:Area/Ncbi/Merge">000233</idno><idno type="wicri:Area/Ncbi/Curation">000233</idno><idno type="wicri:Area/Ncbi/Checkpoint">000233</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Dopaminergic function and dopamine transporter binding assessed with positron emission tomography in Parkinson disease.</title><author><name sortKey="Ribeiro, Maria Joao" sort="Ribeiro, Maria Joao" uniqKey="Ribeiro M" first="Maria-Joao" last="Ribeiro">Maria-Joao Ribeiro</name><affiliation wicri:level="1"><nlm:affiliation>URA CEA-CNRS 2210, Service Hospitalier Frédéric Joliot, 4, place du Général Leclerc, 91401 Orsay, CEDEX, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>URA CEA-CNRS 2210, Service Hospitalier Frédéric Joliot, 4, place du Général Leclerc, 91401 Orsay, CEDEX</wicri:regionArea><wicri:noRegion>CEDEX</wicri:noRegion><wicri:noRegion>CEDEX</wicri:noRegion></affiliation></author><author><name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name></author><author><name sortKey="Loc H, Christian" sort="Loc H, Christian" uniqKey="Loc H C" first="Christian" last="Loc'H">Christian Loc'H</name></author><author><name sortKey="Dupel, Corinne" sort="Dupel, Corinne" uniqKey="Dupel C" first="Corinne" last="Dupel">Corinne Dupel</name></author><author><name sortKey="Nguyen, Jean Paul" sort="Nguyen, Jean Paul" uniqKey="Nguyen J" first="Jean Paul" last="Nguyen">Jean Paul Nguyen</name></author><author><name sortKey="Ponchant, Michel" sort="Ponchant, Michel" uniqKey="Ponchant M" first="Michel" last="Ponchant">Michel Ponchant</name></author><author><name sortKey="Dolle, Frederic" sort="Dolle, Frederic" uniqKey="Dolle F" first="Frédéric" last="Dollé">Frédéric Dollé</name></author><author><name sortKey="Peschanski, Marc" sort="Peschanski, Marc" uniqKey="Peschanski M" first="Marc" last="Peschanski">Marc Peschanski</name></author><author><name sortKey="Hantraye, Philippe" sort="Hantraye, Philippe" uniqKey="Hantraye P" first="Philippe" last="Hantraye">Philippe Hantraye</name></author><author><name sortKey="Cesaro, Pierre" sort="Cesaro, Pierre" uniqKey="Cesaro P" first="Pierre" last="Cesaro">Pierre Cesaro</name></author><author><name sortKey="Samson, Yves" sort="Samson, Yves" uniqKey="Samson Y" first="Yves" last="Samson">Yves Samson</name></author><author><name sortKey="Remy, Philippe" sort="Remy, Philippe" uniqKey="Remy P" first="Philippe" last="Remy">Philippe Remy</name></author></analytic><series><title level="j">Archives of neurology</title><idno type="ISSN">0003-9942</idno><imprint><date when="2002" type="published">2002</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Case-Control Studies</term><term>Corpus Striatum (metabolism)</term><term>Dopamine (metabolism)</term><term>Dopamine Plasma Membrane Transport Proteins</term><term>Female</term><term>Humans</term><term>Male</term><term>Membrane Glycoproteins</term><term>Membrane Transport Proteins (metabolism)</term><term>Middle Aged</term><term>Nerve Tissue Proteins (metabolism)</term><term>Parkinson Disease (diagnostic imaging)</term><term>Parkinson Disease (metabolism)</term><term>Tomography, Emission-Computed</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Dopamine</term><term>Membrane Transport Proteins</term><term>Nerve Tissue Proteins</term></keywords><keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Corpus Striatum</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Case-Control Studies</term><term>Dopamine Plasma Membrane Transport Proteins</term><term>Female</term><term>Humans</term><term>Male</term><term>Membrane Glycoproteins</term><term>Middle Aged</term><term>Tomography, Emission-Computed</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Measuring progression of Parkinson disease (PD) using positron emission tomography may help demonstrate the efficacy of neuroprotective treatments. To date, (18)F-dopa has been the gold standard to measure presynaptic dopaminergic function in PD, but this tracer might overestimate the rate of neuronal death in PD because its uptake also depends on dopamine turnover rather than exclusively on the density of dopaminergic terminals in the striatum. The latter might be assessed using newly developed ligands of the membrane dopamine transporter.</div></front></TEI><affiliations><list><country><li>France</li></country></list><tree><noCountry><name sortKey="Cesaro, Pierre" sort="Cesaro, Pierre" uniqKey="Cesaro P" first="Pierre" last="Cesaro">Pierre Cesaro</name><name sortKey="Dolle, Frederic" sort="Dolle, Frederic" uniqKey="Dolle F" first="Frédéric" last="Dollé">Frédéric Dollé</name><name sortKey="Dupel, Corinne" sort="Dupel, Corinne" uniqKey="Dupel C" first="Corinne" last="Dupel">Corinne Dupel</name><name sortKey="Hantraye, Philippe" sort="Hantraye, Philippe" uniqKey="Hantraye P" first="Philippe" last="Hantraye">Philippe Hantraye</name><name sortKey="Loc H, Christian" sort="Loc H, Christian" uniqKey="Loc H C" first="Christian" last="Loc'H">Christian Loc'H</name><name sortKey="Nguyen, Jean Paul" sort="Nguyen, Jean Paul" uniqKey="Nguyen J" first="Jean Paul" last="Nguyen">Jean Paul Nguyen</name><name sortKey="Peschanski, Marc" sort="Peschanski, Marc" uniqKey="Peschanski M" first="Marc" last="Peschanski">Marc Peschanski</name><name sortKey="Ponchant, Michel" sort="Ponchant, Michel" uniqKey="Ponchant M" first="Michel" last="Ponchant">Michel Ponchant</name><name sortKey="Remy, Philippe" sort="Remy, Philippe" uniqKey="Remy P" first="Philippe" last="Remy">Philippe Remy</name><name sortKey="Samson, Yves" sort="Samson, Yves" uniqKey="Samson Y" first="Yves" last="Samson">Yves Samson</name><name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name></noCountry><country name="France"><noRegion><name sortKey="Ribeiro, Maria Joao" sort="Ribeiro, Maria Joao" uniqKey="Ribeiro M" first="Maria-Joao" last="Ribeiro">Maria-Joao Ribeiro</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/Ncbi/Checkpoint
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000233 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd -nk 000233 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonFranceV1
|flux= Ncbi
|étape= Checkpoint
|type= RBID
|clé= pubmed:11939892
|texte= Dopaminergic function and dopamine transporter binding assessed with positron emission tomography in Parkinson disease.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Checkpoint/RBID.i -Sk "pubmed:11939892" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Checkpoint/biblio.hfd \
| NlmPubMed2Wicri -a ParkinsonFranceV1
| This area was generated with Dilib version V0.6.29. |  |