La maladie de Parkinson en France (serveur d'exploration)

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1-Methyl-4-phenylpyridinium (MMP+) does not exhibit paraquat-like immunoreactivity

Identifieur interne : 005C31 ( Main/Merge ); précédent : 005C30; suivant : 005C32

1-Methyl-4-phenylpyridinium (MMP+) does not exhibit paraquat-like immunoreactivity

Auteurs : P. Houze ; O. Chappey ; H. Gallons ; J.-M. Scherrmann

Source :

RBID : Pascal:91-0126470

Descripteurs français

English descriptors

Abstract

The structural analogy of paraquat with 1-methyl-4-phenylpyridinium (MPP+) has been implied in the aetiology of Parkinson's disease. The cross-reactivity of MPP+ to a specific antibody to paraquat was assessed by radioimmunoassay and was found to be very low. The results suggest that this polyclonal paraquat antibody does not mimic the MPP+ receptor

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Pascal:91-0126470

Le document en format XML

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<title xml:lang="en" level="a">1-Methyl-4-phenylpyridinium (MMP
<sup>+</sup>
) does not exhibit paraquat-like immunoreactivity</title>
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<name sortKey="Houze, P" sort="Houze, P" uniqKey="Houze P" first="P." last="Houze">P. Houze</name>
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<author>
<name sortKey="Chappey, O" sort="Chappey, O" uniqKey="Chappey O" first="O." last="Chappey">O. Chappey</name>
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<author>
<name sortKey="Gallons, H" sort="Gallons, H" uniqKey="Gallons H" first="H." last="Gallons">H. Gallons</name>
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<author>
<name sortKey="Scherrmann, J M" sort="Scherrmann, J M" uniqKey="Scherrmann J" first="J.-M." last="Scherrmann">J.-M. Scherrmann</name>
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<title xml:lang="en" level="a">1-Methyl-4-phenylpyridinium (MMP
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) does not exhibit paraquat-like immunoreactivity</title>
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<name sortKey="Houze, P" sort="Houze, P" uniqKey="Houze P" first="P." last="Houze">P. Houze</name>
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<name sortKey="Chappey, O" sort="Chappey, O" uniqKey="Chappey O" first="O." last="Chappey">O. Chappey</name>
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<name sortKey="Gallons, H" sort="Gallons, H" uniqKey="Gallons H" first="H." last="Gallons">H. Gallons</name>
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<name sortKey="Scherrmann, J M" sort="Scherrmann, J M" uniqKey="Scherrmann J" first="J.-M." last="Scherrmann">J.-M. Scherrmann</name>
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<date when="1990">1990</date>
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<title level="j" type="main">Toxicology letters</title>
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<profileDesc>
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<keywords scheme="KwdEn" xml:lang="en">
<term>Cross reaction</term>
<term>Herbicide</term>
<term>Paraquat</term>
<term>Parkinson disease</term>
<term>Pesticides</term>
<term>Radioimmunoassay</term>
<term>Structure activity relation</term>
<term>Toxicity</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr">
<term>Paraquat</term>
<term>Herbicide</term>
<term>Pesticide</term>
<term>Toxicité</term>
<term>Parkinson maladie</term>
<term>Relation structure activité</term>
<term>Réaction croisée</term>
<term>Méthode radioimmunologique</term>
<term>Pyridinium(1-méthyl-«4»-phényl)</term>
<term>MPTP</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr">
<term>Herbicide</term>
<term>Pesticide</term>
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<front>
<div type="abstract" xml:lang="en">The structural analogy of paraquat with 1-methyl-4-phenylpyridinium (MPP
<sup>+</sup>
) has been implied in the aetiology of Parkinson's disease. The cross-reactivity of MPP
<sup>+</sup>
to a specific antibody to paraquat was assessed by radioimmunoassay and was found to be very low. The results suggest that this polyclonal paraquat antibody does not mimic the MPP
<sup>+</sup>
receptor</div>
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<name sortKey="Chappey, O" sort="Chappey, O" uniqKey="Chappey O" first="O." last="Chappey">O. Chappey</name>
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<name sortKey="Houze, P" sort="Houze, P" uniqKey="Houze P" first="P." last="Houze">P. Houze</name>
<name sortKey="Scherrmann, J M" sort="Scherrmann, J M" uniqKey="Scherrmann J" first="J.-M." last="Scherrmann">J.-M. Scherrmann</name>
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   |wiki=    Wicri/Sante
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   |texte=   1-Methyl-4-phenylpyridinium (MMP+) does not exhibit paraquat-like immunoreactivity
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