Staged lesions through implanted deep brain stimulating electrodes: A new surgical procedure for treating tremor or dyskinesias
Identifieur interne : 003582 ( Main/Merge ); précédent : 003581; suivant : 003583Staged lesions through implanted deep brain stimulating electrodes: A new surgical procedure for treating tremor or dyskinesias
Auteurs : Sylvie Raoul [France] ; Mirella Faighel [France] ; Isabelle Rivier [France] ; Marc Vérin [France] ; Youenn Lajat [France] ; Philippe Damier [France]Source :
- Movement Disorders [ 0885-3185 ] ; 2003-08.
English descriptors
- KwdEn :
- Aged, Antiparkinson Agents (adverse effects), Brain (pathology), Dyskinesia, Drug-Induced (etiology), Dyskinesia, Drug-Induced (surgery), Dyskinesia, Drug-Induced (therapy), Electric Stimulation Therapy (instrumentation), Electrodes, Implanted, Globus Pallidus (surgery), Humans, Magnetic Resonance Imaging, Male, Neurosurgical Procedures (methods), Parkinson Disease (drug therapy), Parkinson Disease (pathology), Parkinson's disease, Tremor (surgery), Tremor (therapy), deep brain stimulation, essential tremor, pallidotomy, thalamotomy.
- MESH :
- chemical , adverse effects : Antiparkinson Agents.
- drug therapy : Parkinson Disease.
- etiology : Dyskinesia, Drug-Induced.
- instrumentation : Electric Stimulation Therapy.
- methods : Neurosurgical Procedures.
- pathology : Brain, Parkinson Disease.
- surgery : Dyskinesia, Drug-Induced, Globus Pallidus, Tremor.
- therapy : Dyskinesia, Drug-Induced, Tremor.
- Aged, Electrodes, Implanted, Humans, Magnetic Resonance Imaging, Male.
Abstract
Thalamotomy and pallidotomy have been shown to have some efficacy for treating some movement disorders such as disabling tremor or parkinsonian levodopa‐induced dyskinesias (LID). Compared to continuous deep brain stimulation (DBS), this surgical procedure has the disadvantage of irreversibility and a lack of adaptability. Making a lesion involves a risk of inducing permanent side effects, especially if the lesion is large, or of observing a resurgence of the symptoms if the lesion is too small. We performed unilateral pallidotomy in one patient suffering from LID and unilateral thalamotomy in two patients suffering from tremor through the lead classically used for DBS. The technique of lead implantation was similar to that used for DBS treatment but, instead of connecting the lead to a pulse generator, it was left in place and used to make a radiofrequency lesion. This technique allowed the lesion to be kept as small as possible, thereby minimizing the risk of permanent side effects and made possible to extend the lesion if the symptoms reappeared. One lesioning session was enough to relieve tremor in the two patients treated by thalamotomy; three lesioning sessions over a 7‐month period were required to relieve drug‐induced dyskinesias in the patient treated by pallidotomy. In all 3 patients, disabling symptoms were still relieved without any permanent side effects 6 months after the last lesion was performed. © 2003 Movement Disorder Society
Url:
DOI: 10.1002/mds.10457
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 001A83
- to stream Istex, to step Curation: 001A81
- to stream Istex, to step Checkpoint: 000C63
- to stream PubMed, to step Corpus: 001088
- to stream PubMed, to step Curation: 001047
- to stream PubMed, to step Checkpoint: 001047
- to stream Ncbi, to step Merge: 000355
- to stream Ncbi, to step Curation: 000355
- to stream Ncbi, to step Checkpoint: 000355
Links to Exploration step
ISTEX:D95F066B2D632FE8102D85E5E18945104B769B35Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Staged lesions through implanted deep brain stimulating electrodes: A new surgical procedure for treating tremor or dyskinesias</title><author><name sortKey="Raoul, Sylvie" sort="Raoul, Sylvie" uniqKey="Raoul S" first="Sylvie" last="Raoul">Sylvie Raoul</name></author><author><name sortKey="Faighel, Mirella" sort="Faighel, Mirella" uniqKey="Faighel M" first="Mirella" last="Faighel">Mirella Faighel</name></author><author><name sortKey="Rivier, Isabelle" sort="Rivier, Isabelle" uniqKey="Rivier I" first="Isabelle" last="Rivier">Isabelle Rivier</name></author><author><name sortKey="Verin, Marc" sort="Verin, Marc" uniqKey="Verin M" first="Marc" last="Vérin">Marc Vérin</name></author><author><name sortKey="Lajat, Youenn" sort="Lajat, Youenn" uniqKey="Lajat Y" first="Youenn" last="Lajat">Youenn Lajat</name></author><author><name sortKey="Damier, Philippe" sort="Damier, Philippe" uniqKey="Damier P" first="Philippe" last="Damier">Philippe Damier</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:D95F066B2D632FE8102D85E5E18945104B769B35</idno><date when="2003" year="2003">2003</date><idno type="doi">10.1002/mds.10457</idno><idno type="url">https://api.istex.fr/document/D95F066B2D632FE8102D85E5E18945104B769B35/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001A83</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001A83</idno><idno type="wicri:Area/Istex/Curation">001A81</idno><idno type="wicri:Area/Istex/Checkpoint">000C63</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000C63</idno><idno type="wicri:doubleKey">0885-3185:2003:Raoul S:staged:lesions:through</idno><idno type="wicri:source">PubMed</idno><idno type="RBID">pubmed:12889085</idno><idno type="wicri:Area/PubMed/Corpus">001088</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001088</idno><idno type="wicri:Area/PubMed/Curation">001047</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001047</idno><idno type="wicri:Area/PubMed/Checkpoint">001047</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001047</idno><idno type="wicri:Area/Ncbi/Merge">000355</idno><idno type="wicri:Area/Ncbi/Curation">000355</idno><idno type="wicri:Area/Ncbi/Checkpoint">000355</idno><idno type="wicri:doubleKey">0885-3185:2003:Raoul S:staged:lesions:through</idno><idno type="wicri:Area/Main/Merge">003582</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Staged lesions through implanted deep brain stimulating electrodes: A new surgical procedure for treating tremor or dyskinesias</title><author><name sortKey="Raoul, Sylvie" sort="Raoul, Sylvie" uniqKey="Raoul S" first="Sylvie" last="Raoul">Sylvie Raoul</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Clinique Neurochirurgicale, Centre Hospitalier Universitaire (CHU) Nantes</wicri:regionArea><wicri:noRegion>Centre Hospitalier Universitaire (CHU) Nantes</wicri:noRegion><wicri:noRegion>Centre Hospitalier Universitaire (CHU) Nantes</wicri:noRegion></affiliation><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Clinique Neurochirurgicale, Hôpital Laennec, CHU Nantes, 44093 Nantes Cedex 1</wicri:regionArea><placeName><region type="region" nuts="2">Pays de la Loire</region><settlement type="city">Nantes</settlement></placeName></affiliation></author><author><name sortKey="Faighel, Mirella" sort="Faighel, Mirella" uniqKey="Faighel M" first="Mirella" last="Faighel">Mirella Faighel</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Clinique Neurologique, Centre d'Investigation Clinique, Institut National de la Santé et de la Recherche Médicale U437, CHU Nantes</wicri:regionArea><wicri:noRegion>CHU Nantes</wicri:noRegion><wicri:noRegion>CHU Nantes</wicri:noRegion></affiliation></author><author><name sortKey="Rivier, Isabelle" sort="Rivier, Isabelle" uniqKey="Rivier I" first="Isabelle" last="Rivier">Isabelle Rivier</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Service de Neurologie, CHU Rennes</wicri:regionArea><wicri:noRegion>CHU Rennes</wicri:noRegion><wicri:noRegion>CHU Rennes</wicri:noRegion></affiliation></author><author><name sortKey="Verin, Marc" sort="Verin, Marc" uniqKey="Verin M" first="Marc" last="Vérin">Marc Vérin</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Service de Neurologie, CHU Rennes</wicri:regionArea><wicri:noRegion>CHU Rennes</wicri:noRegion><wicri:noRegion>CHU Rennes</wicri:noRegion></affiliation></author><author><name sortKey="Lajat, Youenn" sort="Lajat, Youenn" uniqKey="Lajat Y" first="Youenn" last="Lajat">Youenn Lajat</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Clinique Neurochirurgicale, Centre Hospitalier Universitaire (CHU) Nantes</wicri:regionArea><wicri:noRegion>Centre Hospitalier Universitaire (CHU) Nantes</wicri:noRegion><wicri:noRegion>Centre Hospitalier Universitaire (CHU) Nantes</wicri:noRegion></affiliation></author><author><name sortKey="Damier, Philippe" sort="Damier, Philippe" uniqKey="Damier P" first="Philippe" last="Damier">Philippe Damier</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Clinique Neurologique, Centre d'Investigation Clinique, Institut National de la Santé et de la Recherche Médicale U437, CHU Nantes</wicri:regionArea><wicri:noRegion>CHU Nantes</wicri:noRegion><wicri:noRegion>CHU Nantes</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2003-08">2003-08</date><biblScope unit="volume">18</biblScope><biblScope unit="issue">8</biblScope><biblScope unit="page" from="933">933</biblScope><biblScope unit="page" to="938">938</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">D95F066B2D632FE8102D85E5E18945104B769B35</idno><idno type="DOI">10.1002/mds.10457</idno><idno type="ArticleID">MDS10457</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Antiparkinson Agents (adverse effects)</term><term>Brain (pathology)</term><term>Dyskinesia, Drug-Induced (etiology)</term><term>Dyskinesia, Drug-Induced (surgery)</term><term>Dyskinesia, Drug-Induced (therapy)</term><term>Electric Stimulation Therapy (instrumentation)</term><term>Electrodes, Implanted</term><term>Globus Pallidus (surgery)</term><term>Humans</term><term>Magnetic Resonance Imaging</term><term>Male</term><term>Neurosurgical Procedures (methods)</term><term>Parkinson Disease (drug therapy)</term><term>Parkinson Disease (pathology)</term><term>Parkinson's disease</term><term>Tremor (surgery)</term><term>Tremor (therapy)</term><term>deep brain stimulation</term><term>essential tremor</term><term>pallidotomy</term><term>thalamotomy</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Antiparkinson Agents</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Dyskinesia, Drug-Induced</term></keywords><keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Electric Stimulation Therapy</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Neurosurgical Procedures</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Brain</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Dyskinesia, Drug-Induced</term><term>Globus Pallidus</term><term>Tremor</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Dyskinesia, Drug-Induced</term><term>Tremor</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Electrodes, Implanted</term><term>Humans</term><term>Magnetic Resonance Imaging</term><term>Male</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Thalamotomy and pallidotomy have been shown to have some efficacy for treating some movement disorders such as disabling tremor or parkinsonian levodopa‐induced dyskinesias (LID). Compared to continuous deep brain stimulation (DBS), this surgical procedure has the disadvantage of irreversibility and a lack of adaptability. Making a lesion involves a risk of inducing permanent side effects, especially if the lesion is large, or of observing a resurgence of the symptoms if the lesion is too small. We performed unilateral pallidotomy in one patient suffering from LID and unilateral thalamotomy in two patients suffering from tremor through the lead classically used for DBS. The technique of lead implantation was similar to that used for DBS treatment but, instead of connecting the lead to a pulse generator, it was left in place and used to make a radiofrequency lesion. This technique allowed the lesion to be kept as small as possible, thereby minimizing the risk of permanent side effects and made possible to extend the lesion if the symptoms reappeared. One lesioning session was enough to relieve tremor in the two patients treated by thalamotomy; three lesioning sessions over a 7‐month period were required to relieve drug‐induced dyskinesias in the patient treated by pallidotomy. In all 3 patients, disabling symptoms were still relieved without any permanent side effects 6 months after the last lesion was performed. © 2003 Movement Disorder Society</div></front></TEI><double doi="10.1002/mds.10457"><ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Staged lesions through implanted deep brain stimulating electrodes: A new surgical procedure for treating tremor or dyskinesias</title><author><name sortKey="Raoul, Sylvie" sort="Raoul, Sylvie" uniqKey="Raoul S" first="Sylvie" last="Raoul">Sylvie Raoul</name></author><author><name sortKey="Faighel, Mirella" sort="Faighel, Mirella" uniqKey="Faighel M" first="Mirella" last="Faighel">Mirella Faighel</name></author><author><name sortKey="Rivier, Isabelle" sort="Rivier, Isabelle" uniqKey="Rivier I" first="Isabelle" last="Rivier">Isabelle Rivier</name></author><author><name sortKey="Verin, Marc" sort="Verin, Marc" uniqKey="Verin M" first="Marc" last="Vérin">Marc Vérin</name></author><author><name sortKey="Lajat, Youenn" sort="Lajat, Youenn" uniqKey="Lajat Y" first="Youenn" last="Lajat">Youenn Lajat</name></author><author><name sortKey="Damier, Philippe" sort="Damier, Philippe" uniqKey="Damier P" first="Philippe" last="Damier">Philippe Damier</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:D95F066B2D632FE8102D85E5E18945104B769B35</idno><date when="2003" year="2003">2003</date><idno type="doi">10.1002/mds.10457</idno><idno type="url">https://api.istex.fr/document/D95F066B2D632FE8102D85E5E18945104B769B35/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">001A83</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">001A83</idno><idno type="wicri:Area/Istex/Curation">001A81</idno><idno type="wicri:Area/Istex/Checkpoint">000C63</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000C63</idno><idno type="wicri:doubleKey">0885-3185:2003:Raoul S:staged:lesions:through</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Staged lesions through implanted deep brain stimulating electrodes: A new surgical procedure for treating tremor or dyskinesias</title><author><name sortKey="Raoul, Sylvie" sort="Raoul, Sylvie" uniqKey="Raoul S" first="Sylvie" last="Raoul">Sylvie Raoul</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Clinique Neurochirurgicale, Centre Hospitalier Universitaire (CHU) Nantes</wicri:regionArea><wicri:noRegion>Centre Hospitalier Universitaire (CHU) Nantes</wicri:noRegion><wicri:noRegion>Centre Hospitalier Universitaire (CHU) Nantes</wicri:noRegion></affiliation><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Clinique Neurochirurgicale, Hôpital Laennec, CHU Nantes, 44093 Nantes Cedex 1</wicri:regionArea><placeName><region type="region" nuts="2">Pays de la Loire</region><settlement type="city">Nantes</settlement></placeName></affiliation></author><author><name sortKey="Faighel, Mirella" sort="Faighel, Mirella" uniqKey="Faighel M" first="Mirella" last="Faighel">Mirella Faighel</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Clinique Neurologique, Centre d'Investigation Clinique, Institut National de la Santé et de la Recherche Médicale U437, CHU Nantes</wicri:regionArea><wicri:noRegion>CHU Nantes</wicri:noRegion><wicri:noRegion>CHU Nantes</wicri:noRegion></affiliation></author><author><name sortKey="Rivier, Isabelle" sort="Rivier, Isabelle" uniqKey="Rivier I" first="Isabelle" last="Rivier">Isabelle Rivier</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Service de Neurologie, CHU Rennes</wicri:regionArea><wicri:noRegion>CHU Rennes</wicri:noRegion><wicri:noRegion>CHU Rennes</wicri:noRegion></affiliation></author><author><name sortKey="Verin, Marc" sort="Verin, Marc" uniqKey="Verin M" first="Marc" last="Vérin">Marc Vérin</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Service de Neurologie, CHU Rennes</wicri:regionArea><wicri:noRegion>CHU Rennes</wicri:noRegion><wicri:noRegion>CHU Rennes</wicri:noRegion></affiliation></author><author><name sortKey="Lajat, Youenn" sort="Lajat, Youenn" uniqKey="Lajat Y" first="Youenn" last="Lajat">Youenn Lajat</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Clinique Neurochirurgicale, Centre Hospitalier Universitaire (CHU) Nantes</wicri:regionArea><wicri:noRegion>Centre Hospitalier Universitaire (CHU) Nantes</wicri:noRegion><wicri:noRegion>Centre Hospitalier Universitaire (CHU) Nantes</wicri:noRegion></affiliation></author><author><name sortKey="Damier, Philippe" sort="Damier, Philippe" uniqKey="Damier P" first="Philippe" last="Damier">Philippe Damier</name><affiliation wicri:level="1"><country xml:lang="fr">France</country><wicri:regionArea>Clinique Neurologique, Centre d'Investigation Clinique, Institut National de la Santé et de la Recherche Médicale U437, CHU Nantes</wicri:regionArea><wicri:noRegion>CHU Nantes</wicri:noRegion><wicri:noRegion>CHU Nantes</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Movement Disorders</title><title level="j" type="sub">Official Journal of the Movement Disorder Society</title><title level="j" type="abbrev">Mov. Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2003-08">2003-08</date><biblScope unit="volume">18</biblScope><biblScope unit="issue">8</biblScope><biblScope unit="page" from="933">933</biblScope><biblScope unit="page" to="938">938</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">D95F066B2D632FE8102D85E5E18945104B769B35</idno><idno type="DOI">10.1002/mds.10457</idno><idno type="ArticleID">MDS10457</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Parkinson's disease</term><term>deep brain stimulation</term><term>essential tremor</term><term>pallidotomy</term><term>thalamotomy</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Thalamotomy and pallidotomy have been shown to have some efficacy for treating some movement disorders such as disabling tremor or parkinsonian levodopa‐induced dyskinesias (LID). Compared to continuous deep brain stimulation (DBS), this surgical procedure has the disadvantage of irreversibility and a lack of adaptability. Making a lesion involves a risk of inducing permanent side effects, especially if the lesion is large, or of observing a resurgence of the symptoms if the lesion is too small. We performed unilateral pallidotomy in one patient suffering from LID and unilateral thalamotomy in two patients suffering from tremor through the lead classically used for DBS. The technique of lead implantation was similar to that used for DBS treatment but, instead of connecting the lead to a pulse generator, it was left in place and used to make a radiofrequency lesion. This technique allowed the lesion to be kept as small as possible, thereby minimizing the risk of permanent side effects and made possible to extend the lesion if the symptoms reappeared. One lesioning session was enough to relieve tremor in the two patients treated by thalamotomy; three lesioning sessions over a 7‐month period were required to relieve drug‐induced dyskinesias in the patient treated by pallidotomy. In all 3 patients, disabling symptoms were still relieved without any permanent side effects 6 months after the last lesion was performed. © 2003 Movement Disorder Society</div></front></TEI></ISTEX><PubMed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Staged lesions through implanted deep brain stimulating electrodes: a new surgical procedure for treating tremor or dyskinesias.</title><author><name sortKey="Raoul, Sylvie" sort="Raoul, Sylvie" uniqKey="Raoul S" first="Sylvie" last="Raoul">Sylvie Raoul</name><affiliation wicri:level="1"><nlm:affiliation>Clinique Neurochirurgicale, Centre Hospitalier Universitaire (CHU) Nantes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Clinique Neurochirurgicale, Centre Hospitalier Universitaire (CHU) Nantes</wicri:regionArea><wicri:noRegion>Centre Hospitalier Universitaire (CHU) Nantes</wicri:noRegion><wicri:noRegion>Centre Hospitalier Universitaire (CHU) Nantes</wicri:noRegion></affiliation></author><author><name sortKey="Faighel, Mirella" sort="Faighel, Mirella" uniqKey="Faighel M" first="Mirella" last="Faighel">Mirella Faighel</name></author><author><name sortKey="Rivier, Isabelle" sort="Rivier, Isabelle" uniqKey="Rivier I" first="Isabelle" last="Rivier">Isabelle Rivier</name></author><author><name sortKey="Verin, Marc" sort="Verin, Marc" uniqKey="Verin M" first="Marc" last="Vérin">Marc Vérin</name></author><author><name sortKey="Lajat, Youenn" sort="Lajat, Youenn" uniqKey="Lajat Y" first="Youenn" last="Lajat">Youenn Lajat</name></author><author><name sortKey="Damier, Philippe" sort="Damier, Philippe" uniqKey="Damier P" first="Philippe" last="Damier">Philippe Damier</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2003">2003</date><idno type="RBID">pubmed:12889085</idno><idno type="pmid">12889085</idno><idno type="doi">10.1002/mds.10457</idno><idno type="wicri:Area/PubMed/Corpus">001088</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001088</idno><idno type="wicri:Area/PubMed/Curation">001047</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001047</idno><idno type="wicri:Area/PubMed/Checkpoint">001047</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001047</idno><idno type="wicri:Area/Ncbi/Merge">000355</idno><idno type="wicri:Area/Ncbi/Curation">000355</idno><idno type="wicri:Area/Ncbi/Checkpoint">000355</idno><idno type="wicri:doubleKey">0885-3185:2003:Raoul S:staged:lesions:through</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Staged lesions through implanted deep brain stimulating electrodes: a new surgical procedure for treating tremor or dyskinesias.</title><author><name sortKey="Raoul, Sylvie" sort="Raoul, Sylvie" uniqKey="Raoul S" first="Sylvie" last="Raoul">Sylvie Raoul</name><affiliation wicri:level="1"><nlm:affiliation>Clinique Neurochirurgicale, Centre Hospitalier Universitaire (CHU) Nantes, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Clinique Neurochirurgicale, Centre Hospitalier Universitaire (CHU) Nantes</wicri:regionArea><wicri:noRegion>Centre Hospitalier Universitaire (CHU) Nantes</wicri:noRegion><wicri:noRegion>Centre Hospitalier Universitaire (CHU) Nantes</wicri:noRegion></affiliation></author><author><name sortKey="Faighel, Mirella" sort="Faighel, Mirella" uniqKey="Faighel M" first="Mirella" last="Faighel">Mirella Faighel</name></author><author><name sortKey="Rivier, Isabelle" sort="Rivier, Isabelle" uniqKey="Rivier I" first="Isabelle" last="Rivier">Isabelle Rivier</name></author><author><name sortKey="Verin, Marc" sort="Verin, Marc" uniqKey="Verin M" first="Marc" last="Vérin">Marc Vérin</name></author><author><name sortKey="Lajat, Youenn" sort="Lajat, Youenn" uniqKey="Lajat Y" first="Youenn" last="Lajat">Youenn Lajat</name></author><author><name sortKey="Damier, Philippe" sort="Damier, Philippe" uniqKey="Damier P" first="Philippe" last="Damier">Philippe Damier</name></author></analytic><series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title><idno type="ISSN">0885-3185</idno><imprint><date when="2003" type="published">2003</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Antiparkinson Agents (adverse effects)</term><term>Brain (pathology)</term><term>Dyskinesia, Drug-Induced (etiology)</term><term>Dyskinesia, Drug-Induced (surgery)</term><term>Dyskinesia, Drug-Induced (therapy)</term><term>Electric Stimulation Therapy (instrumentation)</term><term>Electrodes, Implanted</term><term>Globus Pallidus (surgery)</term><term>Humans</term><term>Magnetic Resonance Imaging</term><term>Male</term><term>Neurosurgical Procedures (methods)</term><term>Parkinson Disease (drug therapy)</term><term>Parkinson Disease (pathology)</term><term>Tremor (surgery)</term><term>Tremor (therapy)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Antiparkinson Agents</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Dyskinesia, Drug-Induced</term></keywords><keywords scheme="MESH" qualifier="instrumentation" xml:lang="en"><term>Electric Stimulation Therapy</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Neurosurgical Procedures</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Brain</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Dyskinesia, Drug-Induced</term><term>Globus Pallidus</term><term>Tremor</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Dyskinesia, Drug-Induced</term><term>Tremor</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Electrodes, Implanted</term><term>Humans</term><term>Magnetic Resonance Imaging</term><term>Male</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Thalamotomy and pallidotomy have been shown to have some efficacy for treating some movement disorders such as disabling tremor or parkinsonian levodopa-induced dyskinesias (LID). Compared to continuous deep brain stimulation (DBS), this surgical procedure has the disadvantage of irreversibility and a lack of adaptability. Making a lesion involves a risk of inducing permanent side effects, especially if the lesion is large, or of observing a resurgence of the symptoms if the lesion is too small. We performed unilateral pallidotomy in one patient suffering from LID and unilateral thalamotomy in two patients suffering from tremor through the lead classically used for DBS. The technique of lead implantation was similar to that used for DBS treatment but, instead of connecting the lead to a pulse generator, it was left in place and used to make a radiofrequency lesion. This technique allowed the lesion to be kept as small as possible, thereby minimizing the risk of permanent side effects and made possible to extend the lesion if the symptoms reappeared. One lesioning session was enough to relieve tremor in the two patients treated by thalamotomy; three lesioning sessions over a 7-month period were required to relieve drug-induced dyskinesias in the patient treated by pallidotomy. In all 3 patients, disabling symptoms were still relieved without any permanent side effects 6 months after the last lesion was performed.</div></front></TEI></PubMed></double></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 003582 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 003582 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonFranceV1
|flux= Main
|étape= Merge
|type= RBID
|clé= ISTEX:D95F066B2D632FE8102D85E5E18945104B769B35
|texte= Staged lesions through implanted deep brain stimulating electrodes: A new surgical procedure for treating tremor or dyskinesias
}}
| This area was generated with Dilib version V0.6.29. |  |