La maladie de Parkinson en France (serveur d'exploration)

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[Comparison of quality of life in multiple system atrophy and Parkinson's disease].

Identifieur interne : 002017 ( Main/Merge ); précédent : 002016; suivant : 002018

[Comparison of quality of life in multiple system atrophy and Parkinson's disease].

Auteurs : F. Torny [France] ; M. Lacoste ; H. Videaud ; M. Chouly ; M-C Parveau ; P. Couratier

Source :

RBID : pubmed:19324385

English descriptors

Abstract

Quality of life (QoL) in multiple system atrophy (MSA) is thought to be poorer than in Parkinson's disease (PD), primarily because of motor impairment, autonomic dysfunction and depression. The aim of the study was to investigate QoL in 10 patients with probable MSA (parkinsonian subtype) compared with 10 PD patients matched for motor disability on UPDRS III motor score.

Url:
DOI: 10.1016/j.neurol.2009.02.001
PubMed: 19324385

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Links to Exploration step

pubmed:19324385

Le document en format XML

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<div type="abstract" xml:lang="en">PURPOSE: Quality of life (QoL) in multiple system atrophy (MSA) is thought to be poorer than in Parkinson's disease (PD), primarily because of motor impairment, autonomic dysfunction and depression. The aim of the study was to investigate QoL in 10 patients with probable MSA (parkinsonian subtype) compared with 10 PD patients matched for motor disability on UPDRS III motor score. METHODS: All patients were ambulatory and non-demented. Mean durations of disease in MSA and PD patients were respectively 3.6 and 9.0 years. QoL was assessed using the SF-36 health-related questionnaire and a life satisfaction visual analogue scale. Patients were also evaluated for cognitive function (Mattis Dementia Rating Scale [Mattis DRS], Wisconsin Card Sorting Test [WCST], Stroop, Fluencies), depression (Beck Depression Inventory-II [BDI-II]), apathy (Modified Apathy Evaluation Scale) and were screened for non-motor symptoms (NMS Quest). RESULTS: The only difference in QoL between MSA and PD patients matched for motor disability was that the SF-36 vitality subscore was more impaired in MSA and negatively correlated with interference index on Stroop word colour testing. Depression and non-motor symptoms were associated with poorer QoL in both groups. Among MSA patients, cognitive impairment (Stroop interference index) and apathy also had a negative impact. CONCLUSION: There was no major difference in QoL between MSA and PD patients matched for motor disability with a disease duration about 5 years longer. The SF-36 vitality subscore was more impaired in MSA and associated with interference sensitivity.</div>
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<name sortKey="Parveau, M C" sort="Parveau, M C" uniqKey="Parveau M" first="M-C" last="Parveau">M-C Parveau</name>
</author>
<author>
<name sortKey="Couratier, P" sort="Couratier, P" uniqKey="Couratier P" first="P" last="Couratier">P. Couratier</name>
</author>
</analytic>
<series>
<title level="j">Revue neurologique</title>
<idno type="ISSN">0035-3787</idno>
<imprint>
<date when="2009" type="published">2009</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
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<profileDesc>
<textClass>
<keywords scheme="KwdEn" xml:lang="en">
<term>Activities of Daily Living</term>
<term>Age of Onset</term>
<term>Aged</term>
<term>Antidepressive Agents (therapeutic use)</term>
<term>Color Vision</term>
<term>Emotions</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Multiple System Atrophy (drug therapy)</term>
<term>Multiple System Atrophy (physiopathology)</term>
<term>Multiple System Atrophy (psychology)</term>
<term>Parkinson Disease (drug therapy)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Parkinson Disease (psychology)</term>
<term>Quality of Life</term>
<term>Stroop Test</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en">
<term>Antidepressive Agents</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en">
<term>Multiple System Atrophy</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en">
<term>Multiple System Atrophy</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en">
<term>Multiple System Atrophy</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Activities of Daily Living</term>
<term>Age of Onset</term>
<term>Aged</term>
<term>Color Vision</term>
<term>Emotions</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Quality of Life</term>
<term>Stroop Test</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front>
<div type="abstract" xml:lang="en">Quality of life (QoL) in multiple system atrophy (MSA) is thought to be poorer than in Parkinson's disease (PD), primarily because of motor impairment, autonomic dysfunction and depression. The aim of the study was to investigate QoL in 10 patients with probable MSA (parkinsonian subtype) compared with 10 PD patients matched for motor disability on UPDRS III motor score.</div>
</front>
</TEI>
</PubMed>
</double>
</record>

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