The Changing Face of Parkinson's Disease-Associated Psychosis: A Cross-Sectional Study Based on the New NINDS-NIMH Criteria
Identifieur interne : 001E31 ( Main/Merge ); précédent : 001E30; suivant : 001E32The Changing Face of Parkinson's Disease-Associated Psychosis: A Cross-Sectional Study Based on the New NINDS-NIMH Criteria
Auteurs : Gilles Fenelon [France] ; Thierry Soulas [France] ; Franck Zenasni [France] ; Laurent Cleret De Langavant [France]Source :
- Movement disorders [ 0885-3185 ] ; 2010.
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- Pascal (Inist)
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- KwdEn :
Abstract
New criteria for Parkinson's disease-associated psychosis (PDAP) were recently proposed by a NINDS-NIMH working group. We assessed 116 consecutive unselected outpatients with PD for the existence of psychotic symptoms during the previous month, using a structured questionnaire covering the whole spectrum of PDAP symptoms. Hallucinations occurred in 42% of the patients (visual: 16%; nonvisual: 35%), delusions in 4%, and minor symptoms in 45% (sense of presence, visual illusions, or passage hallucinations). The prevalence of PDAP was 43% when the usual definition was used (hallucinations and/or delusions) and 60% when the NINDS-NIHM criteria were used. Correlations between PDAP and patient characteristics varied with the definition of PDAP. These findings suggest that the epidemiology of PDAP should be re-evaluated with the new criteria. Minor symptoms and nonvisual hallucinations are an important part of the PDAP spectrum, which has commonly been restricted to visual hallucinations and delusions.
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<front><div type="abstract" xml:lang="en">New criteria for Parkinson's disease-associated psychosis (PDAP) were recently proposed by a NINDS-NIMH working group. We assessed 116 consecutive unselected outpatients with PD for the existence of psychotic symptoms during the previous month, using a structured questionnaire covering the whole spectrum of PDAP symptoms. Hallucinations occurred in 42% of the patients (visual: 16%; nonvisual: 35%), delusions in 4%, and minor symptoms in 45% (sense of presence, visual illusions, or passage hallucinations). The prevalence of PDAP was 43% when the usual definition was used (hallucinations and/or delusions) and 60% when the NINDS-NIHM criteria were used. Correlations between PDAP and patient characteristics varied with the definition of PDAP. These findings suggest that the epidemiology of PDAP should be re-evaluated with the new criteria. Minor symptoms and nonvisual hallucinations are an important part of the PDAP spectrum, which has commonly been restricted to visual hallucinations and delusions.</div>
</front>
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<tree><country name="France"><region name="Île-de-France"><name sortKey="Fenelon, Gilles" sort="Fenelon, Gilles" uniqKey="Fenelon G" first="Gilles" last="Fenelon">Gilles Fenelon</name>
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<name sortKey="Cleret De Langavant, Laurent" sort="Cleret De Langavant, Laurent" uniqKey="Cleret De Langavant L" first="Laurent" last="Cleret De Langavant">Laurent Cleret De Langavant</name>
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<name sortKey="Zenasni, Franck" sort="Zenasni, Franck" uniqKey="Zenasni F" first="Franck" last="Zenasni">Franck Zenasni</name>
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