Loss of REM sleep features across nighttime in REM sleep behavior disorder.
Identifieur interne : 000246 ( Main/Merge ); précédent : 000245; suivant : 000247Loss of REM sleep features across nighttime in REM sleep behavior disorder.
Auteurs : Dario Arnaldi [Italie] ; Alice Latimier [France] ; Smaranda Leu-Semenescu [France] ; Marie Vidailhet [France] ; Isabelle Arnulf [France]Source :
- Sleep medicine [ 1878-5506 ] ; 2016.
English descriptors
- KwdEn :
- Adult, Aged, Chronobiology Disorders (physiopathology), Electromyography, Female, Humans, Male, Melatonin (pharmacology), Melatonin (therapeutic use), Middle Aged, Parkinson Disease (physiopathology), Polysomnography (methods), REM Sleep Behavior Disorder (drug therapy), REM Sleep Behavior Disorder (physiopathology), Sleep Stages.
- MESH :
- chemical , pharmacology : Melatonin.
- drug therapy : REM Sleep Behavior Disorder.
- methods : Polysomnography.
- physiopathology : Chronobiology Disorders, Parkinson Disease, REM Sleep Behavior Disorder.
- chemical , therapeutic use : Melatonin.
- Adult, Aged, Electromyography, Female, Humans, Male, Middle Aged, Sleep Stages.
- mix :
Abstract
Melatonin is a chronobiotic treatment which also alleviates rapid eye movement (REM) sleep behavior disorder (RBD). Because the mechanisms of this benefit are unclear, we evaluated the clock-dependent REM sleep characteristics in patients with RBD, whether idiopathic (iRBD) or associated with Parkinson's Disease (PD), and we compared findings with PD patients without RBD and with healthy subjects.
Url:
DOI: 10.1016/j.sleep.2015.10.019
PubMed: 26847988
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000234
- to stream PubMed, to step Curation: 000233
- to stream PubMed, to step Checkpoint: 000233
- to stream Ncbi, to step Merge: 001943
- to stream Ncbi, to step Curation: 001943
- to stream Ncbi, to step Checkpoint: 001943
- to stream Hal, to step Corpus: 000641
- to stream Hal, to step Curation: 000641
- to stream Hal, to step Checkpoint: 000083
Links to Exploration step
pubmed:26847988Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Loss of REM sleep features across nighttime in REM sleep behavior disorder.</title>
<author><name sortKey="Arnaldi, Dario" sort="Arnaldi, Dario" uniqKey="Arnaldi D" first="Dario" last="Arnaldi">Dario Arnaldi</name>
<affiliation wicri:level="1"><nlm:affiliation>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Clinical Neurology, Department of Neuroscience (DINOGMI), University of Genoa, Genova, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Clinical Neurology, Department of Neuroscience (DINOGMI), University of Genoa, Genova</wicri:regionArea>
<wicri:noRegion>Genova</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Latimier, Alice" sort="Latimier, Alice" uniqKey="Latimier A" first="Alice" last="Latimier">Alice Latimier</name>
<affiliation wicri:level="3"><nlm:affiliation>Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Leu Semenescu, Smaranda" sort="Leu Semenescu, Smaranda" uniqKey="Leu Semenescu S" first="Smaranda" last="Leu-Semenescu">Smaranda Leu-Semenescu</name>
<affiliation wicri:level="3"><nlm:affiliation>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name>
<affiliation wicri:level="3"><nlm:affiliation>Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France; Neurology Department, APHP- Pitié-Salpêtrière Hospital, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France; Neurology Department, APHP- Pitié-Salpêtrière Hospital, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Arnulf, Isabelle" sort="Arnulf, Isabelle" uniqKey="Arnulf I" first="Isabelle" last="Arnulf">Isabelle Arnulf</name>
<affiliation wicri:level="3"><nlm:affiliation>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France. Electronic address: isabelle.arnulf@psl.aphp.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2016">2016</date>
<idno type="RBID">pubmed:26847988</idno>
<idno type="pmid">26847988</idno>
<idno type="doi">10.1016/j.sleep.2015.10.019</idno>
<idno type="wicri:Area/PubMed/Corpus">000234</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000234</idno>
<idno type="wicri:Area/PubMed/Curation">000233</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000233</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000233</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000233</idno>
<idno type="wicri:Area/Ncbi/Merge">001943</idno>
<idno type="wicri:Area/Ncbi/Curation">001943</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001943</idno>
<idno type="wicri:source">HAL</idno>
<idno type="RBID">Hal:hal-01292432</idno>
<idno type="url">http://hal.upmc.fr/hal-01292432</idno>
<idno type="wicri:Area/Hal/Corpus">000641</idno>
<idno type="wicri:Area/Hal/Curation">000641</idno>
<idno type="wicri:Area/Hal/Checkpoint">000083</idno>
<idno type="wicri:explorRef" wicri:stream="Hal" wicri:step="Checkpoint">000083</idno>
<idno type="wicri:doubleKey">1389-9457:2016:Arnaldi D:loss:of:rem</idno>
<idno type="wicri:Area/Main/Merge">000246</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Loss of REM sleep features across nighttime in REM sleep behavior disorder.</title>
<author><name sortKey="Arnaldi, Dario" sort="Arnaldi, Dario" uniqKey="Arnaldi D" first="Dario" last="Arnaldi">Dario Arnaldi</name>
<affiliation wicri:level="1"><nlm:affiliation>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Clinical Neurology, Department of Neuroscience (DINOGMI), University of Genoa, Genova, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Clinical Neurology, Department of Neuroscience (DINOGMI), University of Genoa, Genova</wicri:regionArea>
<wicri:noRegion>Genova</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Latimier, Alice" sort="Latimier, Alice" uniqKey="Latimier A" first="Alice" last="Latimier">Alice Latimier</name>
<affiliation wicri:level="3"><nlm:affiliation>Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Leu Semenescu, Smaranda" sort="Leu Semenescu, Smaranda" uniqKey="Leu Semenescu S" first="Smaranda" last="Leu-Semenescu">Smaranda Leu-Semenescu</name>
<affiliation wicri:level="3"><nlm:affiliation>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name>
<affiliation wicri:level="3"><nlm:affiliation>Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France; Neurology Department, APHP- Pitié-Salpêtrière Hospital, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France; Neurology Department, APHP- Pitié-Salpêtrière Hospital, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Arnulf, Isabelle" sort="Arnulf, Isabelle" uniqKey="Arnulf I" first="Isabelle" last="Arnulf">Isabelle Arnulf</name>
<affiliation wicri:level="3"><nlm:affiliation>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France. Electronic address: isabelle.arnulf@psl.aphp.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Sleep medicine</title>
<idno type="eISSN">1878-5506</idno>
<imprint><date when="2016" type="published">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Chronobiology Disorders (physiopathology)</term>
<term>Electromyography</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Melatonin (pharmacology)</term>
<term>Melatonin (therapeutic use)</term>
<term>Middle Aged</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Polysomnography (methods)</term>
<term>REM Sleep Behavior Disorder (drug therapy)</term>
<term>REM Sleep Behavior Disorder (physiopathology)</term>
<term>Sleep Stages</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Melatonin</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>REM Sleep Behavior Disorder</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Polysomnography</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Chronobiology Disorders</term>
<term>Parkinson Disease</term>
<term>REM Sleep Behavior Disorder</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Melatonin</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Electromyography</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Sleep Stages</term>
</keywords>
<keywords scheme="mix" xml:lang="en"><term>Circadian</term>
<term>Melatonin</term>
<term>PD</term>
<term>RBD</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Melatonin is a chronobiotic treatment which also alleviates rapid eye movement (REM) sleep behavior disorder (RBD). Because the mechanisms of this benefit are unclear, we evaluated the clock-dependent REM sleep characteristics in patients with RBD, whether idiopathic (iRBD) or associated with Parkinson's Disease (PD), and we compared findings with PD patients without RBD and with healthy subjects.</div>
</front>
</TEI>
<double doi="10.1016/j.sleep.2015.10.019"><HAL><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Loss of REM sleep features across nighttime in REM sleep behavior disorder</title>
<author><name sortKey="Arnaldi, Dario" sort="Arnaldi, Dario" uniqKey="Arnaldi D" first="Dario" last="Arnaldi">Dario Arnaldi</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-424248" status="INCOMING"> <orgName>Service des pathologies du sommeil</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation active="#struct-353778" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-353778" type="direct"><org type="institution" xml:id="struct-353778" status="VALID"> <orgName>CHU Pitié-Salpêtrière [APHP]</orgName>
<desc> <address> <addrLine>47-83 Boulevard de l'Hôpital, 75013 Paris</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.aphp.fr/contenu/hopital-universitaire-pitie-salpetriere-0</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Latimier, Alice" sort="Latimier, Alice" uniqKey="Latimier A" first="Alice" last="Latimier">Alice Latimier</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-246044" status="VALID"> <idno type="RNSR">200918525B</idno>
<orgName>Institut du Cerveau et de la Moëlle Epinière</orgName>
<orgName type="acronym">ICM</orgName>
<desc> <address> <addrLine>47-83 Boulevard de l'Hôpital 75651 Paris Cedex 13</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="UM75" active="#struct-93591" type="direct"></relation>
<relation name="U1127" active="#struct-303623" type="direct"></relation>
<relation active="#struct-353778" type="direct"></relation>
<relation name="UMR7225" active="#struct-441569" type="direct"></relation>
</listRelation>
<tutelles><tutelle name="UM75" active="#struct-93591" type="direct"><org type="institution" xml:id="struct-93591" status="VALID"> <orgName>Université Pierre et Marie Curie - Paris 6</orgName>
<orgName type="acronym">UPMC</orgName>
<desc> <address> <addrLine>4 place Jussieu - 75005 Paris</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.upmc.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="U1127" active="#struct-303623" type="direct"><org type="institution" xml:id="struct-303623" status="VALID"> <idno type="IdRef">026388278</idno>
<orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
<orgName type="acronym">INSERM</orgName>
<desc> <address> <addrLine>101, rue de Tolbiac, 75013 Paris </addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inserm.fr</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-353778" type="direct"><org type="institution" xml:id="struct-353778" status="VALID"> <orgName>CHU Pitié-Salpêtrière [APHP]</orgName>
<desc> <address> <addrLine>47-83 Boulevard de l'Hôpital, 75013 Paris</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.aphp.fr/contenu/hopital-universitaire-pitie-salpetriere-0</ref>
</desc>
</org>
</tutelle>
<tutelle name="UMR7225" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"> <idno type="IdRef">02636817X</idno>
<idno type="ISNI">0000000122597504</idno>
<orgName>Centre National de la Recherche Scientifique</orgName>
<orgName type="acronym">CNRS</orgName>
<date type="start">1939-10-19</date>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">http://www.cnrs.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Leu Semenescu, Smaranda" sort="Leu Semenescu, Smaranda" uniqKey="Leu Semenescu S" first="Smaranda" last="Leu-Semenescu">Smaranda Leu-Semenescu</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-424248" status="INCOMING"> <orgName>Service des pathologies du sommeil</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation active="#struct-353778" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-353778" type="direct"><org type="institution" xml:id="struct-353778" status="VALID"> <orgName>CHU Pitié-Salpêtrière [APHP]</orgName>
<desc> <address> <addrLine>47-83 Boulevard de l'Hôpital, 75013 Paris</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.aphp.fr/contenu/hopital-universitaire-pitie-salpetriere-0</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name>
<affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-73659" status="VALID"> <orgName>Service d'Explorations Fonctionnelles Neurologie [CHU Pitié-Salpétrière]</orgName>
<desc> <address> <addrLine>47-83, boulevard de l'Hôpital 75651 Paris Cedex 13</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation> <relation active="#struct-353778" type="direct"></relation>
<relation active="#struct-300068" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-353778" type="direct"><org type="institution" xml:id="struct-353778" status="VALID"> <orgName>CHU Pitié-Salpêtrière [APHP]</orgName>
<desc> <address> <addrLine>47-83 Boulevard de l'Hôpital, 75013 Paris</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.aphp.fr/contenu/hopital-universitaire-pitie-salpetriere-0</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-300068" type="direct"><org type="institution" xml:id="struct-300068" status="VALID"> <orgName>Assistance publique - Hôpitaux de Paris (AP-HP)</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Arnulf, Isabelle" sort="Arnulf, Isabelle" uniqKey="Arnulf I" first="Isabelle" last="Arnulf">Isabelle Arnulf</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-424248" status="INCOMING"> <orgName>Service des pathologies du sommeil</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation active="#struct-353778" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-353778" type="direct"><org type="institution" xml:id="struct-353778" status="VALID"> <orgName>CHU Pitié-Salpêtrière [APHP]</orgName>
<desc> <address> <addrLine>47-83 Boulevard de l'Hôpital, 75013 Paris</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.aphp.fr/contenu/hopital-universitaire-pitie-salpetriere-0</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">HAL</idno>
<idno type="RBID">Hal:hal-01292432</idno>
<idno type="halId">hal-01292432</idno>
<idno type="halUri">http://hal.upmc.fr/hal-01292432</idno>
<idno type="url">http://hal.upmc.fr/hal-01292432</idno>
<idno type="doi">10.1016/j.sleep.2015.10.019</idno>
<date when="2016-01">2016-01</date>
<idno type="wicri:Area/Hal/Corpus">000641</idno>
<idno type="wicri:Area/Hal/Curation">000641</idno>
<idno type="wicri:Area/Hal/Checkpoint">000083</idno>
<idno type="wicri:explorRef" wicri:stream="Hal" wicri:step="Checkpoint">000083</idno>
<idno type="wicri:doubleKey">1389-9457:2016:Arnaldi D:loss:of:rem</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Loss of REM sleep features across nighttime in REM sleep behavior disorder</title>
<author><name sortKey="Arnaldi, Dario" sort="Arnaldi, Dario" uniqKey="Arnaldi D" first="Dario" last="Arnaldi">Dario Arnaldi</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-424248" status="INCOMING"> <orgName>Service des pathologies du sommeil</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation active="#struct-353778" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-353778" type="direct"><org type="institution" xml:id="struct-353778" status="VALID"> <orgName>CHU Pitié-Salpêtrière [APHP]</orgName>
<desc> <address> <addrLine>47-83 Boulevard de l'Hôpital, 75013 Paris</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.aphp.fr/contenu/hopital-universitaire-pitie-salpetriere-0</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Latimier, Alice" sort="Latimier, Alice" uniqKey="Latimier A" first="Alice" last="Latimier">Alice Latimier</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-246044" status="VALID"> <idno type="RNSR">200918525B</idno>
<orgName>Institut du Cerveau et de la Moëlle Epinière</orgName>
<orgName type="acronym">ICM</orgName>
<desc> <address> <addrLine>47-83 Boulevard de l'Hôpital 75651 Paris Cedex 13</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation> <relation name="UM75" active="#struct-93591" type="direct"></relation>
<relation name="U1127" active="#struct-303623" type="direct"></relation>
<relation active="#struct-353778" type="direct"></relation>
<relation name="UMR7225" active="#struct-441569" type="direct"></relation>
</listRelation>
<tutelles><tutelle name="UM75" active="#struct-93591" type="direct"><org type="institution" xml:id="struct-93591" status="VALID"> <orgName>Université Pierre et Marie Curie - Paris 6</orgName>
<orgName type="acronym">UPMC</orgName>
<desc> <address> <addrLine>4 place Jussieu - 75005 Paris</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.upmc.fr/</ref>
</desc>
</org>
</tutelle>
<tutelle name="U1127" active="#struct-303623" type="direct"><org type="institution" xml:id="struct-303623" status="VALID"> <idno type="IdRef">026388278</idno>
<orgName>Institut National de la Santé et de la Recherche Médicale</orgName>
<orgName type="acronym">INSERM</orgName>
<desc> <address> <addrLine>101, rue de Tolbiac, 75013 Paris </addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.inserm.fr</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-353778" type="direct"><org type="institution" xml:id="struct-353778" status="VALID"> <orgName>CHU Pitié-Salpêtrière [APHP]</orgName>
<desc> <address> <addrLine>47-83 Boulevard de l'Hôpital, 75013 Paris</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.aphp.fr/contenu/hopital-universitaire-pitie-salpetriere-0</ref>
</desc>
</org>
</tutelle>
<tutelle name="UMR7225" active="#struct-441569" type="direct"><org type="institution" xml:id="struct-441569" status="VALID"> <idno type="IdRef">02636817X</idno>
<idno type="ISNI">0000000122597504</idno>
<orgName>Centre National de la Recherche Scientifique</orgName>
<orgName type="acronym">CNRS</orgName>
<date type="start">1939-10-19</date>
<desc> <address> <country key="FR"></country>
</address>
<ref type="url">http://www.cnrs.fr/</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Leu Semenescu, Smaranda" sort="Leu Semenescu, Smaranda" uniqKey="Leu Semenescu S" first="Smaranda" last="Leu-Semenescu">Smaranda Leu-Semenescu</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-424248" status="INCOMING"> <orgName>Service des pathologies du sommeil</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation active="#struct-353778" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-353778" type="direct"><org type="institution" xml:id="struct-353778" status="VALID"> <orgName>CHU Pitié-Salpêtrière [APHP]</orgName>
<desc> <address> <addrLine>47-83 Boulevard de l'Hôpital, 75013 Paris</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.aphp.fr/contenu/hopital-universitaire-pitie-salpetriere-0</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name>
<affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-73659" status="VALID"> <orgName>Service d'Explorations Fonctionnelles Neurologie [CHU Pitié-Salpétrière]</orgName>
<desc> <address> <addrLine>47-83, boulevard de l'Hôpital 75651 Paris Cedex 13</addrLine>
<country key="FR"></country>
</address>
</desc>
<listRelation> <relation active="#struct-353778" type="direct"></relation>
<relation active="#struct-300068" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-353778" type="direct"><org type="institution" xml:id="struct-353778" status="VALID"> <orgName>CHU Pitié-Salpêtrière [APHP]</orgName>
<desc> <address> <addrLine>47-83 Boulevard de l'Hôpital, 75013 Paris</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.aphp.fr/contenu/hopital-universitaire-pitie-salpetriere-0</ref>
</desc>
</org>
</tutelle>
<tutelle active="#struct-300068" type="direct"><org type="institution" xml:id="struct-300068" status="VALID"> <orgName>Assistance publique - Hôpitaux de Paris (AP-HP)</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
<author><name sortKey="Arnulf, Isabelle" sort="Arnulf, Isabelle" uniqKey="Arnulf I" first="Isabelle" last="Arnulf">Isabelle Arnulf</name>
<affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-424248" status="INCOMING"> <orgName>Service des pathologies du sommeil</orgName>
<desc> <address> <country key="FR"></country>
</address>
</desc>
<listRelation> <relation active="#struct-353778" type="direct"></relation>
</listRelation>
<tutelles><tutelle active="#struct-353778" type="direct"><org type="institution" xml:id="struct-353778" status="VALID"> <orgName>CHU Pitié-Salpêtrière [APHP]</orgName>
<desc> <address> <addrLine>47-83 Boulevard de l'Hôpital, 75013 Paris</addrLine>
<country key="FR"></country>
</address>
<ref type="url">http://www.aphp.fr/contenu/hopital-universitaire-pitie-salpetriere-0</ref>
</desc>
</org>
</tutelle>
</tutelles>
</hal:affiliation>
<country>France</country>
</affiliation>
</author>
</analytic>
<idno type="DOI">10.1016/j.sleep.2015.10.019</idno>
<series><title level="j">Sleep Medicine</title>
<idno type="ISSN">1389-9457</idno>
<imprint><date type="datePub">2016-01</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="mix" xml:lang="en"><term>Circadian</term>
<term>Melatonin</term>
<term>PD</term>
<term>RBD</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">ObjectivesMelatonin is a chronobiotic treatment which also alleviates rapid eye movement (REM) sleep behavior disorder (RBD). Because the mechanisms of this benefit are unclear, we evaluated the clock-dependent REM sleep characteristics in patients with RBD, whether idiopathic (iRBD) or associated with Parkinson's Disease (PD), and we compared findings with PD patients without RBD and with healthy subjects.MethodsAn overnight videopolysomnography was performed in ten iRBD patients, ten PD patients with RBD (PD + RBD+), ten PD patients without RBD (PD + RBD−), and ten controls. The rapid eye movement frequency per minute (REMs index), the tonic and phasic electromyographic (EMG) activity of the levator menti muscle, and the duration of each REM sleep episode were evaluated. A generalized linear model was applied in each group, with the REM sleep cycle (four ordinal levels) as the dependent variable, as a function of REMs index, REM sleep duration, and tonic and phasic EMG activity.ResultsFrom the first to the fourth sleep cycle, REM sleep duration progressively increased in controls only, REMs index increased in subjects without RBD but not in patients with RBD, whether idiopathic or associated with PD, whereas tonic and phasic EMG activity did not change.ConclusionsPatients with PD or iRBD lost the physiologic nocturnal increase in REM sleep duration, and patients with RBD (either with or without PD) lost the increase of REMs frequency across the night, suggesting an alteration in the circadian system in RBD. This supports the hypothesis of a direct effect of melatonin on RBD symptoms by its chronobiotic activity.</div>
</front>
</TEI>
</HAL>
<PubMed><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Loss of REM sleep features across nighttime in REM sleep behavior disorder.</title>
<author><name sortKey="Arnaldi, Dario" sort="Arnaldi, Dario" uniqKey="Arnaldi D" first="Dario" last="Arnaldi">Dario Arnaldi</name>
<affiliation wicri:level="1"><nlm:affiliation>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Clinical Neurology, Department of Neuroscience (DINOGMI), University of Genoa, Genova, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Clinical Neurology, Department of Neuroscience (DINOGMI), University of Genoa, Genova</wicri:regionArea>
<wicri:noRegion>Genova</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Latimier, Alice" sort="Latimier, Alice" uniqKey="Latimier A" first="Alice" last="Latimier">Alice Latimier</name>
<affiliation wicri:level="3"><nlm:affiliation>Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Leu Semenescu, Smaranda" sort="Leu Semenescu, Smaranda" uniqKey="Leu Semenescu S" first="Smaranda" last="Leu-Semenescu">Smaranda Leu-Semenescu</name>
<affiliation wicri:level="3"><nlm:affiliation>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name>
<affiliation wicri:level="3"><nlm:affiliation>Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France; Neurology Department, APHP- Pitié-Salpêtrière Hospital, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France; Neurology Department, APHP- Pitié-Salpêtrière Hospital, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Arnulf, Isabelle" sort="Arnulf, Isabelle" uniqKey="Arnulf I" first="Isabelle" last="Arnulf">Isabelle Arnulf</name>
<affiliation wicri:level="3"><nlm:affiliation>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France. Electronic address: isabelle.arnulf@psl.aphp.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2016">2016</date>
<idno type="RBID">pubmed:26847988</idno>
<idno type="pmid">26847988</idno>
<idno type="doi">10.1016/j.sleep.2015.10.019</idno>
<idno type="wicri:Area/PubMed/Corpus">000234</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000234</idno>
<idno type="wicri:Area/PubMed/Curation">000233</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000233</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000233</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000233</idno>
<idno type="wicri:Area/Ncbi/Merge">001943</idno>
<idno type="wicri:Area/Ncbi/Curation">001943</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001943</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Loss of REM sleep features across nighttime in REM sleep behavior disorder.</title>
<author><name sortKey="Arnaldi, Dario" sort="Arnaldi, Dario" uniqKey="Arnaldi D" first="Dario" last="Arnaldi">Dario Arnaldi</name>
<affiliation wicri:level="1"><nlm:affiliation>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Clinical Neurology, Department of Neuroscience (DINOGMI), University of Genoa, Genova, Italy.</nlm:affiliation>
<country xml:lang="fr">Italie</country>
<wicri:regionArea>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Clinical Neurology, Department of Neuroscience (DINOGMI), University of Genoa, Genova</wicri:regionArea>
<wicri:noRegion>Genova</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Latimier, Alice" sort="Latimier, Alice" uniqKey="Latimier A" first="Alice" last="Latimier">Alice Latimier</name>
<affiliation wicri:level="3"><nlm:affiliation>Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Leu Semenescu, Smaranda" sort="Leu Semenescu, Smaranda" uniqKey="Leu Semenescu S" first="Smaranda" last="Leu-Semenescu">Smaranda Leu-Semenescu</name>
<affiliation wicri:level="3"><nlm:affiliation>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Vidailhet, Marie" sort="Vidailhet, Marie" uniqKey="Vidailhet M" first="Marie" last="Vidailhet">Marie Vidailhet</name>
<affiliation wicri:level="3"><nlm:affiliation>Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France; Neurology Department, APHP- Pitié-Salpêtrière Hospital, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France; Neurology Department, APHP- Pitié-Salpêtrière Hospital, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Arnulf, Isabelle" sort="Arnulf, Isabelle" uniqKey="Arnulf I" first="Isabelle" last="Arnulf">Isabelle Arnulf</name>
<affiliation wicri:level="3"><nlm:affiliation>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris, France. Electronic address: isabelle.arnulf@psl.aphp.fr.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Sleep Disorders Unit, APHP-Pitié-Salpêtrière Hospital, Paris, France; Brain Research Institute-UPMC Paris 6 Univ, Inserm U 1127, CNRS UMR 7225, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Sleep medicine</title>
<idno type="eISSN">1878-5506</idno>
<imprint><date when="2016" type="published">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Chronobiology Disorders (physiopathology)</term>
<term>Electromyography</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Melatonin (pharmacology)</term>
<term>Melatonin (therapeutic use)</term>
<term>Middle Aged</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Polysomnography (methods)</term>
<term>REM Sleep Behavior Disorder (drug therapy)</term>
<term>REM Sleep Behavior Disorder (physiopathology)</term>
<term>Sleep Stages</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Melatonin</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>REM Sleep Behavior Disorder</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Polysomnography</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Chronobiology Disorders</term>
<term>Parkinson Disease</term>
<term>REM Sleep Behavior Disorder</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Melatonin</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Electromyography</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Sleep Stages</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Melatonin is a chronobiotic treatment which also alleviates rapid eye movement (REM) sleep behavior disorder (RBD). Because the mechanisms of this benefit are unclear, we evaluated the clock-dependent REM sleep characteristics in patients with RBD, whether idiopathic (iRBD) or associated with Parkinson's Disease (PD), and we compared findings with PD patients without RBD and with healthy subjects.</div>
</front>
</TEI>
</PubMed>
</double>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000246 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 000246 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= ParkinsonFranceV1 |flux= Main |étape= Merge |type= RBID |clé= pubmed:26847988 |texte= Loss of REM sleep features across nighttime in REM sleep behavior disorder. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Merge/RBID.i -Sk "pubmed:26847988" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Merge/biblio.hfd \ | NlmPubMed2Wicri -a ParkinsonFranceV1
![]() | This area was generated with Dilib version V0.6.29. | ![]() |