Do cognitive changes of Parkinson's disease result from dopamine depletion?
Identifieur interne : 004701 ( Main/Exploration ); précédent : 004700; suivant : 004702Do cognitive changes of Parkinson's disease result from dopamine depletion?
Auteurs : B. Dubois [France] ; B. PillonSource :
- Journal of neural transmission. Supplementum [ 0303-6995 ] ; 1995.
English descriptors
- KwdEn :
- MESH :
- chemical , physiology : Dopamine.
- etiology : Cognition Disorders.
- physiopathology : Cerebral Cortex, Cognition Disorders, Frontal Lobe, Parkinson Disease.
- psychology : Parkinson Disease.
- Humans.
Abstract
Cognitive changes have long been observed in patients with Parkinson's disease: visuo-spatial deficits, memory disorders, dysexecutive syndrome. Given the modulatory role of the basal ganglia and related structures, these deficits might result from more fundamental disorders concerning the allocation of attentional resources, the temporal organization of behavior, the maintenance of representations in working memory or the self-elaboration of internal strategy, all of which resemble dysfunctions of processes that are commonly considered to be controlled by the frontal lobes. This suggests a functional continuity between the basal ganglia and association areas of the prefrontal cortex. The recent description in primates of parallel, segregated loops that interconnect well defined subregions of the basal ganglia to discrete areas of the prefrontal cortex via the thalamus may give some support to this hypothesis.
PubMed: 8748606
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 001650
- to stream PubMed, to step Curation: 001609
- to stream PubMed, to step Checkpoint: 001609
- to stream Ncbi, to step Merge: 001E11
- to stream Ncbi, to step Curation: 001E11
- to stream Ncbi, to step Checkpoint: 001E11
- to stream Main, to step Merge: 005003
- to stream Main, to step Curation: 004701
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Do cognitive changes of Parkinson's disease result from dopamine depletion?</title>
<author><name sortKey="Dubois, B" sort="Dubois, B" uniqKey="Dubois B" first="B" last="Dubois">B. Dubois</name>
<affiliation wicri:level="3"><nlm:affiliation>Fédération de Neurologie and INSERM U 289, Hopital de la Salpétrière, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Fédération de Neurologie and INSERM U 289, Hopital de la Salpétrière, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pillon, B" sort="Pillon, B" uniqKey="Pillon B" first="B" last="Pillon">B. Pillon</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="1995">1995</date>
<idno type="RBID">pubmed:8748606</idno>
<idno type="pmid">8748606</idno>
<idno type="wicri:Area/PubMed/Corpus">001650</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001650</idno>
<idno type="wicri:Area/PubMed/Curation">001609</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001609</idno>
<idno type="wicri:Area/PubMed/Checkpoint">001609</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001609</idno>
<idno type="wicri:Area/Ncbi/Merge">001E11</idno>
<idno type="wicri:Area/Ncbi/Curation">001E11</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001E11</idno>
<idno type="wicri:doubleKey">0303-6995:1995:Dubois B:do:cognitive:changes</idno>
<idno type="wicri:Area/Main/Merge">005003</idno>
<idno type="wicri:Area/Main/Curation">004701</idno>
<idno type="wicri:Area/Main/Exploration">004701</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Do cognitive changes of Parkinson's disease result from dopamine depletion?</title>
<author><name sortKey="Dubois, B" sort="Dubois, B" uniqKey="Dubois B" first="B" last="Dubois">B. Dubois</name>
<affiliation wicri:level="3"><nlm:affiliation>Fédération de Neurologie and INSERM U 289, Hopital de la Salpétrière, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Fédération de Neurologie and INSERM U 289, Hopital de la Salpétrière, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pillon, B" sort="Pillon, B" uniqKey="Pillon B" first="B" last="Pillon">B. Pillon</name>
</author>
</analytic>
<series><title level="j">Journal of neural transmission. Supplementum</title>
<idno type="ISSN">0303-6995</idno>
<imprint><date when="1995" type="published">1995</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Cerebral Cortex (physiopathology)</term>
<term>Cognition Disorders (etiology)</term>
<term>Cognition Disorders (physiopathology)</term>
<term>Dopamine (physiology)</term>
<term>Frontal Lobe (physiopathology)</term>
<term>Humans</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Parkinson Disease (psychology)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="physiology" xml:lang="en"><term>Dopamine</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Cognition Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Cerebral Cortex</term>
<term>Cognition Disorders</term>
<term>Frontal Lobe</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Humans</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Cognitive changes have long been observed in patients with Parkinson's disease: visuo-spatial deficits, memory disorders, dysexecutive syndrome. Given the modulatory role of the basal ganglia and related structures, these deficits might result from more fundamental disorders concerning the allocation of attentional resources, the temporal organization of behavior, the maintenance of representations in working memory or the self-elaboration of internal strategy, all of which resemble dysfunctions of processes that are commonly considered to be controlled by the frontal lobes. This suggests a functional continuity between the basal ganglia and association areas of the prefrontal cortex. The recent description in primates of parallel, segregated loops that interconnect well defined subregions of the basal ganglia to discrete areas of the prefrontal cortex via the thalamus may give some support to this hypothesis.</div>
</front>
</TEI>
<affiliations><list><country><li>France</li>
</country>
<region><li>Île-de-France</li>
</region>
<settlement><li>Paris</li>
</settlement>
</list>
<tree><noCountry><name sortKey="Pillon, B" sort="Pillon, B" uniqKey="Pillon B" first="B" last="Pillon">B. Pillon</name>
</noCountry>
<country name="France"><region name="Île-de-France"><name sortKey="Dubois, B" sort="Dubois, B" uniqKey="Dubois B" first="B" last="Dubois">B. Dubois</name>
</region>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 004701 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 004701 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= ParkinsonFranceV1 |flux= Main |étape= Exploration |type= RBID |clé= pubmed:8748606 |texte= Do cognitive changes of Parkinson's disease result from dopamine depletion? }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:8748606" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a ParkinsonFranceV1
![]() | This area was generated with Dilib version V0.6.29. | ![]() |