Effect of gabapentin on oculomotor control and parkinsonism in patients with progressive supranuclear palsy
Identifieur interne : 002721 ( Main/Exploration ); précédent : 002720; suivant : 002722Effect of gabapentin on oculomotor control and parkinsonism in patients with progressive supranuclear palsy
Auteurs : A. Poujois [France] ; M. Vidailhet [France] ; J. Trocello [France] ; F. Bourdain [France] ; B. Gaymard [France] ; S. Rivaud-Péchoux [France]Source :
- European Journal of Neurology [ 1351-5101 ] ; 2007-09.
English descriptors
- KwdEn :
- Aged, Amines (therapeutic use), Antiparkinson Agents (therapeutic use), Cyclohexanecarboxylic Acids (therapeutic use), Eye Movements (drug effects), Female, Humans, Male, Parkinson Disease (complications), Parkinson Disease (drug therapy), Severity of Illness Index, Supranuclear Palsy, Progressive (complications), Supranuclear Palsy, Progressive (drug therapy), antisaccade, frontal dysfunction, gabapentin, gamma-Aminobutyric Acid (therapeutic use), parkinsonism, progressive supranuclear palsy.
- MESH :
- chemical , therapeutic use : Amines, Antiparkinson Agents, Cyclohexanecarboxylic Acids, gamma-Aminobutyric Acid.
- complications : Parkinson Disease, Supranuclear Palsy, Progressive.
- drug effects : Eye Movements.
- drug therapy : Parkinson Disease, Supranuclear Palsy, Progressive.
- Aged, Female, Humans, Male, Severity of Illness Index.
Abstract
The efficacy of gabapentin on motor, oculomotor and frontal lobe symptoms was evaluated in patients with progressive supranuclear palsy (PSP) in a pilot study. Fourteen patients were included and seven of them received gabapentin. Clinical evaluation and horizontal eye movement recordings were performed at inclusion and 5‐weeks later. Motor score and saccade latency in the visually guided saccade (VGS) task were identical in the two groups. However, the error rate in the antisaccade task was significantly decreased in the gabapentin group. This preliminary study shows that gabapentin improves reflexive saccade inhibition in patients with PSP but does not improve the latency of VGSs.
Url:
DOI: 10.1111/j.1468-1331.2007.01687.x
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000300
- to stream Istex, to step Curation: 000300
- to stream Istex, to step Checkpoint: 000917
- to stream PubMed, to step Corpus: 000D59
- to stream PubMed, to step Curation: 000D19
- to stream PubMed, to step Checkpoint: 000D19
- to stream Ncbi, to step Merge: 000760
- to stream Ncbi, to step Curation: 000760
- to stream Ncbi, to step Checkpoint: 000760
- to stream Main, to step Merge: 002986
- to stream Main, to step Curation: 002721
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Effect of gabapentin on oculomotor control and parkinsonism in patients with progressive supranuclear palsy</title>
<author><name sortKey="Poujois, A" sort="Poujois, A" uniqKey="Poujois A" first="A." last="Poujois">A. Poujois</name>
</author>
<author><name sortKey="Vidailhet, M" sort="Vidailhet, M" uniqKey="Vidailhet M" first="M." last="Vidailhet">M. Vidailhet</name>
</author>
<author><name sortKey="Trocello, J" sort="Trocello, J" uniqKey="Trocello J" first="J." last="Trocello">J. Trocello</name>
</author>
<author><name sortKey="Bourdain, F" sort="Bourdain, F" uniqKey="Bourdain F" first="F." last="Bourdain">F. Bourdain</name>
</author>
<author><name sortKey="Gaymard, B" sort="Gaymard, B" uniqKey="Gaymard B" first="B." last="Gaymard">B. Gaymard</name>
</author>
<author><name sortKey="Rivaud Echoux, S" sort="Rivaud Echoux, S" uniqKey="Rivaud Echoux S" first="S." last="Rivaud-Péchoux">S. Rivaud-Péchoux</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:0D9C9EB4FE4DC18314A22410F25486DA8D1E5264</idno>
<date when="2007" year="2007">2007</date>
<idno type="doi">10.1111/j.1468-1331.2007.01687.x</idno>
<idno type="url">https://api.istex.fr/document/0D9C9EB4FE4DC18314A22410F25486DA8D1E5264/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000300</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000300</idno>
<idno type="wicri:Area/Istex/Curation">000300</idno>
<idno type="wicri:Area/Istex/Checkpoint">000917</idno>
<idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000917</idno>
<idno type="wicri:doubleKey">1351-5101:2007:Poujois A:effect:of:gabapentin</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:17718702</idno>
<idno type="wicri:Area/PubMed/Corpus">000D59</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000D59</idno>
<idno type="wicri:Area/PubMed/Curation">000D19</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000D19</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000D19</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000D19</idno>
<idno type="wicri:Area/Ncbi/Merge">000760</idno>
<idno type="wicri:Area/Ncbi/Curation">000760</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000760</idno>
<idno type="wicri:Area/Main/Merge">002986</idno>
<idno type="wicri:Area/Main/Curation">002721</idno>
<idno type="wicri:Area/Main/Exploration">002721</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Effect of gabapentin on oculomotor control and parkinsonism in patients with progressive supranuclear palsy</title>
<author><name sortKey="Poujois, A" sort="Poujois, A" uniqKey="Poujois A" first="A." last="Poujois">A. Poujois</name>
<affiliation wicri:level="1"><country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neurologie, CHU Saint‐Etienne, Saint‐Etienne</wicri:regionArea>
<wicri:noRegion>Saint‐Etienne</wicri:noRegion>
<wicri:noRegion>Saint‐Etienne</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vidailhet, M" sort="Vidailhet, M" uniqKey="Vidailhet M" first="M." last="Vidailhet">M. Vidailhet</name>
<affiliation wicri:level="3"><country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neurologie, Hôpital Saint‐Antoine, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><country xml:lang="fr">France</country>
<wicri:regionArea>INSERM U679, Hôpital de la Salpêtrière, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Trocello, J" sort="Trocello, J" uniqKey="Trocello J" first="J." last="Trocello">J. Trocello</name>
<affiliation wicri:level="3"><country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neurologie, Hôpital Saint‐Antoine, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bourdain, F" sort="Bourdain, F" uniqKey="Bourdain F" first="F." last="Bourdain">F. Bourdain</name>
<affiliation wicri:level="3"><country xml:lang="fr">France</country>
<wicri:regionArea>Service de Neurologie, Hôpital Saint‐Antoine, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Gaymard, B" sort="Gaymard, B" uniqKey="Gaymard B" first="B." last="Gaymard">B. Gaymard</name>
<affiliation wicri:level="3"><country xml:lang="fr">France</country>
<wicri:regionArea>INSERM U679, Hôpital de la Salpêtrière, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Rivaud Echoux, S" sort="Rivaud Echoux, S" uniqKey="Rivaud Echoux S" first="S." last="Rivaud-Péchoux">S. Rivaud-Péchoux</name>
<affiliation wicri:level="3"><country xml:lang="fr">France</country>
<wicri:regionArea>INSERM U679, Hôpital de la Salpêtrière, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">European Journal of Neurology</title>
<idno type="ISSN">1351-5101</idno>
<idno type="eISSN">1468-1331</idno>
<imprint><publisher>Blackwell Publishing Ltd</publisher>
<pubPlace>Oxford, UK</pubPlace>
<date type="published" when="2007-09">2007-09</date>
<biblScope unit="volume">14</biblScope>
<biblScope unit="issue">9</biblScope>
<biblScope unit="page" from="1060">1060</biblScope>
<biblScope unit="page" to="1062">1062</biblScope>
</imprint>
<idno type="ISSN">1351-5101</idno>
</series>
<idno type="istex">0D9C9EB4FE4DC18314A22410F25486DA8D1E5264</idno>
<idno type="DOI">10.1111/j.1468-1331.2007.01687.x</idno>
<idno type="ArticleID">ENE1687</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">1351-5101</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term>
<term>Amines (therapeutic use)</term>
<term>Antiparkinson Agents (therapeutic use)</term>
<term>Cyclohexanecarboxylic Acids (therapeutic use)</term>
<term>Eye Movements (drug effects)</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Parkinson Disease (complications)</term>
<term>Parkinson Disease (drug therapy)</term>
<term>Severity of Illness Index</term>
<term>Supranuclear Palsy, Progressive (complications)</term>
<term>Supranuclear Palsy, Progressive (drug therapy)</term>
<term>antisaccade</term>
<term>frontal dysfunction</term>
<term>gabapentin</term>
<term>gamma-Aminobutyric Acid (therapeutic use)</term>
<term>parkinsonism</term>
<term>progressive supranuclear palsy</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Amines</term>
<term>Antiparkinson Agents</term>
<term>Cyclohexanecarboxylic Acids</term>
<term>gamma-Aminobutyric Acid</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term>
<term>Supranuclear Palsy, Progressive</term>
</keywords>
<keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Eye Movements</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinson Disease</term>
<term>Supranuclear Palsy, Progressive</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Severity of Illness Index</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The efficacy of gabapentin on motor, oculomotor and frontal lobe symptoms was evaluated in patients with progressive supranuclear palsy (PSP) in a pilot study. Fourteen patients were included and seven of them received gabapentin. Clinical evaluation and horizontal eye movement recordings were performed at inclusion and 5‐weeks later. Motor score and saccade latency in the visually guided saccade (VGS) task were identical in the two groups. However, the error rate in the antisaccade task was significantly decreased in the gabapentin group. This preliminary study shows that gabapentin improves reflexive saccade inhibition in patients with PSP but does not improve the latency of VGSs.</div>
</front>
</TEI>
<affiliations><list><country><li>France</li>
</country>
<region><li>Île-de-France</li>
</region>
<settlement><li>Paris</li>
</settlement>
</list>
<tree><country name="France"><noRegion><name sortKey="Poujois, A" sort="Poujois, A" uniqKey="Poujois A" first="A." last="Poujois">A. Poujois</name>
</noRegion>
<name sortKey="Bourdain, F" sort="Bourdain, F" uniqKey="Bourdain F" first="F." last="Bourdain">F. Bourdain</name>
<name sortKey="Gaymard, B" sort="Gaymard, B" uniqKey="Gaymard B" first="B." last="Gaymard">B. Gaymard</name>
<name sortKey="Rivaud Echoux, S" sort="Rivaud Echoux, S" uniqKey="Rivaud Echoux S" first="S." last="Rivaud-Péchoux">S. Rivaud-Péchoux</name>
<name sortKey="Trocello, J" sort="Trocello, J" uniqKey="Trocello J" first="J." last="Trocello">J. Trocello</name>
<name sortKey="Vidailhet, M" sort="Vidailhet, M" uniqKey="Vidailhet M" first="M." last="Vidailhet">M. Vidailhet</name>
<name sortKey="Vidailhet, M" sort="Vidailhet, M" uniqKey="Vidailhet M" first="M." last="Vidailhet">M. Vidailhet</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002721 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002721 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Sante |area= ParkinsonFranceV1 |flux= Main |étape= Exploration |type= RBID |clé= ISTEX:0D9C9EB4FE4DC18314A22410F25486DA8D1E5264 |texte= Effect of gabapentin on oculomotor control and parkinsonism in patients with progressive supranuclear palsy }}
This area was generated with Dilib version V0.6.29. |