Alleviation of off-period dystonia in Parkinson disease by a microlesion following subthalamic implantation.
Identifieur interne : 001A66 ( Main/Exploration ); précédent : 001A65; suivant : 001A67Alleviation of off-period dystonia in Parkinson disease by a microlesion following subthalamic implantation.
Auteurs : Stéphane Derrey [France] ; Romain Lefaucheur ; Nathalie Chastan ; Emmanuel Gérardin ; Didier Hannequin ; Marie Desbordes ; David MaltêteSource :
- Journal of neurosurgery [ 1933-0693 ] ; 2010.
English descriptors
- KwdEn :
- Adult, Aged, Deep Brain Stimulation (methods), Dystonia (physiopathology), Dystonia (therapy), Electrodes, Implanted, Female, Follow-Up Studies, Globus Pallidus (physiopathology), Globus Pallidus (surgery), Humans, Male, Microsurgery, Middle Aged, Neurologic Examination, Parkinson Disease (physiopathology), Parkinson Disease (therapy), Subthalamic Nucleus (physiopathology), Subthalamic Nucleus (surgery), Treatment Outcome.
- MESH :
- methods : Deep Brain Stimulation.
- physiopathology : Dystonia, Globus Pallidus, Parkinson Disease, Subthalamic Nucleus.
- surgery : Globus Pallidus, Subthalamic Nucleus.
- therapy : Dystonia, Parkinson Disease.
- Adult, Aged, Electrodes, Implanted, Female, Follow-Up Studies, Humans, Male, Microsurgery, Middle Aged, Neurologic Examination, Treatment Outcome.
Abstract
A collision/implantation or microlesion effect is commonly described after subthalamic nucleus (STN) implantation for high-frequency stimulation, and this is presumed to reflect disruption of cells and/or fibers. Off-period dystonia, a frequent cause of disability in patients with advanced Parkinson disease, can lead to the need for surgical treatment. The authors assessed the early effect of this microlesion on off-period dystonia.
Url:
DOI: 10.3171/2009.10.JNS091032
PubMed: 19877801
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">A collision/implantation or microlesion effect is commonly described after subthalamic nucleus (STN) implantation for high-frequency stimulation, and this is presumed to reflect disruption of cells and/or fibers. Off-period dystonia, a frequent cause of disability in patients with advanced Parkinson disease, can lead to the need for surgical treatment. The authors assessed the early effect of this microlesion on off-period dystonia.</div>
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<tree><noCountry><name sortKey="Chastan, Nathalie" sort="Chastan, Nathalie" uniqKey="Chastan N" first="Nathalie" last="Chastan">Nathalie Chastan</name>
<name sortKey="Desbordes, Marie" sort="Desbordes, Marie" uniqKey="Desbordes M" first="Marie" last="Desbordes">Marie Desbordes</name>
<name sortKey="Gerardin, Emmanuel" sort="Gerardin, Emmanuel" uniqKey="Gerardin E" first="Emmanuel" last="Gérardin">Emmanuel Gérardin</name>
<name sortKey="Hannequin, Didier" sort="Hannequin, Didier" uniqKey="Hannequin D" first="Didier" last="Hannequin">Didier Hannequin</name>
<name sortKey="Lefaucheur, Romain" sort="Lefaucheur, Romain" uniqKey="Lefaucheur R" first="Romain" last="Lefaucheur">Romain Lefaucheur</name>
<name sortKey="Maltete, David" sort="Maltete, David" uniqKey="Maltete D" first="David" last="Maltête">David Maltête</name>
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<country name="France"><noRegion><name sortKey="Derrey, Stephane" sort="Derrey, Stephane" uniqKey="Derrey S" first="Stéphane" last="Derrey">Stéphane Derrey</name>
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