[Digestive amines of bacterial origin and behavior disorders. Apropos of a case].
Identifieur interne : 004469 ( Main/Exploration ); précédent : 004468; suivant : 004470[Digestive amines of bacterial origin and behavior disorders. Apropos of a case].
Auteurs : J M Gabastou [France] ; L. Nugon-Baudon ; Y. Robert ; C. Manuel ; P. Vaissade ; E. Bourgeon ; M. Sibeud ; O. Szylit ; P. BourliouxSource :
- Pathologie-biologie [ 0369-8114 ] ; 1996.
English descriptors
- KwdEn :
- MESH :
- chemical , analysis : Adrenergic Agents, Amphetamine, Cadaverine, Histamine, Putrescine.
- chemistry : Feces.
- metabolism : Social Behavior Disorders.
- Adult, Chromatography, High Pressure Liquid, Humans, Male, Reference Values, Time Factors.
Abstract
Implication of amines in central nervous system diseases such as migraine, Parkinson disease, epilepsy and depressive illness, is well established. On an other hand, intestinal flora is responsible for the production of specific metabolites such as amines, particularly histamine, tyramine, putrescine and cadaverine. These amines can be absorbed in situ and, through unknown mechanisms, may affect the host's behavior. Most of the data about the pathological activities of bacterial amines concern animals. The concentrations of histamine, tyramine, putrescine and cadaverine in the feces of the studied "controls" appeared steady over time. For the patient presenting clastic crisis without any starting factor, variations appear to overcome the "controls" values, with a great variability. At least tyramine, putrescine and cadaverine concentrations variations are striking by superposed and seem associated to the arising hyper agressivity crisis.
PubMed: 8763591
Affiliations:
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Le document en format XML
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<term>Chromatography, High Pressure Liquid</term>
<term>Feces (chemistry)</term>
<term>Histamine (analysis)</term>
<term>Humans</term>
<term>Male</term>
<term>Putrescine (analysis)</term>
<term>Reference Values</term>
<term>Social Behavior Disorders (metabolism)</term>
<term>Time Factors</term>
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<term>Putrescine</term>
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<front><div type="abstract" xml:lang="en">Implication of amines in central nervous system diseases such as migraine, Parkinson disease, epilepsy and depressive illness, is well established. On an other hand, intestinal flora is responsible for the production of specific metabolites such as amines, particularly histamine, tyramine, putrescine and cadaverine. These amines can be absorbed in situ and, through unknown mechanisms, may affect the host's behavior. Most of the data about the pathological activities of bacterial amines concern animals. The concentrations of histamine, tyramine, putrescine and cadaverine in the feces of the studied "controls" appeared steady over time. For the patient presenting clastic crisis without any starting factor, variations appear to overcome the "controls" values, with a great variability. At least tyramine, putrescine and cadaverine concentrations variations are striking by superposed and seem associated to the arising hyper agressivity crisis.</div>
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