La maladie de Parkinson en France (serveur d'exploration)

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[Psychic disorders and somnolence].

Identifieur interne : 003300 ( Main/Exploration ); précédent : 003299; suivant : 003301

[Psychic disorders and somnolence].

Auteurs : J L Houeto [France] ; I. Arnulf

Source :

RBID : pubmed:12690669

English descriptors

Abstract

Hallucinations (mainly visual), psychosis and excessive daytime sleepiness are potential side-effects of dopaminergic treatment. They may require a reduction or suppression of dopaminergic agonists, and the prescription of atypical neuroleptic agents or vigilance-enhancing drugs. The recent description of narcolepsy-like sleep onset in rapid eye movement sleep periods synchronous with hypnagogic hallucinations in patients with dopaminergic-induced psychosis or excessive daytime sleepiness, suggests that the mesodiencephalic lesions may predispose to the psychic effects of dopaminergic treatment. Disease-related mood disorders, sexual compulsions, gambling or levodopa addiction may also be amplified by the antiparkinsonian treatment. These complications illustrate the neuro-psychic aspect of Parkinson's disease: psychic troubles may result from a subtle balance between the direct effects of drugs, the pre-morbid pathological personality and the cortical and subcortical lesions.

PubMed: 12690669


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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<nlm:affiliation>Fédération de Neurologie, Centre d'Investigation Clinique, Groupe Hospitalier Pitié-Salpêtrière, Paris, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Fédération de Neurologie, Centre d'Investigation Clinique, Groupe Hospitalier Pitié-Salpêtrière, Paris</wicri:regionArea>
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<region type="region">Île-de-France</region>
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{{Explor lien
   |wiki=    Wicri/Sante
   |area=    ParkinsonFranceV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:12690669
   |texte=   [Psychic disorders and somnolence].
}}

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