Study of telomere length and different markers of oxidative stress in patients with Parkinson's disease.
Identifieur interne : 001536 ( Main/Exploration ); précédent : 001535; suivant : 001537Study of telomere length and different markers of oxidative stress in patients with Parkinson's disease.
Auteurs : G. Watfa [France] ; C. Dragonas ; T. Brosche ; R. Dittrich ; C C Sieber ; C. Alecu ; A. Benetos ; R. NzietchuengSource :
- The journal of nutrition, health & aging [ 1760-4788 ] ; 2011.
English descriptors
- KwdEn :
- MESH :
- chemical , analysis : Biomarkers.
- chemical , blood : Glutathione.
- genetics : Parkinson Disease.
- chemical , metabolism : Superoxide Dismutase.
- physiology : Aging.
- ultrastructure : Telomere.
- Aged, Case-Control Studies, Female, Humans, Male, Oxidative Stress.
Abstract
Many studies have shown that short telomere length (TL) is associated with high oxidative stress and various age-related diseases. Parkinson's disease (PD) is an age-related disease, and although its pathogenic mechanism is uncertain, oxidative stress is believed to be implicated in this pathology. The aim of this case-control study was to assess both TL and the different markers of oxidative stress in elderly patients with PD compared to age control subjects.
PubMed: 21437559
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Many studies have shown that short telomere length (TL) is associated with high oxidative stress and various age-related diseases. Parkinson's disease (PD) is an age-related disease, and although its pathogenic mechanism is uncertain, oxidative stress is believed to be implicated in this pathology. The aim of this case-control study was to assess both TL and the different markers of oxidative stress in elderly patients with PD compared to age control subjects.</div>
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