ParkinsonFranceV1, Main, Exploration, bibRecord, 000169

Risk factors of mortality during the first year after low energy osteoporosis fracture: a retrospective case-control study

Identifieur interne : 000169 ( Main/Exploration ); précédent : 000168; suivant : 000170

Risk factors of mortality during the first year after low energy osteoporosis fracture: a retrospective case-control study

Auteurs : Aurore Lloret [France] ; Guillaume Coiffier [France] ; Tiffen Couchouron [France] ; Aleth Perdriger [France] ; Pascal Guggenbuhl [France]

Source :

Clinical Cases in Mineral and Bone Metabolism [ 1724-8914 ] ; 2016.

RBID : PMC:5119709

Abstract

SummaryIntroduction

Osteoporotic fractures are a major public health problem because of the morbidity and mortality of fracture complications. The objective of this study was to examine predictive factors of mortality during the first year after an osteoporotic fracture.

Methods

It is a retrospective case-control study using data of a group of 1081 patients aged over 50 years with severe osteoporotic fractures by the Rennes university hospital emergency department from August 2007 to September 2008. Patients (cases) who died during the year following the fracture were compared with others who had survived (controls) one year after the fracture, matched on age, sex and type of fracture. Pre-fracture comorbidities and complications after the fractures were studied.

Results

Forty-two cases and 126 controls were analyzed without significant differences in age, sex or type of fracture. On univariate analysis, previous neoplasia, neurodegenerative disease, walking aids, thromboembolic complication, post fracture infection, post fracture heart failure, post fracture acute respiratory failure were associated with more mortality after osteoporotic fracture. After multivariate analysis, only previous neoplasia (OR = 4.63 [1.79 – 11.95]; p = 0.02) and acute respiratory failure after fracture (OR = 28.15 [5.75 – 137.9]; p<0.001) were retained as predictive factors during the year following the fracture.

Conclusion

Patients died more often from their co-morbidities than direct complications of their fractures. Osteoporotic fracture seems to be a marker of poor health status and a factor which may hasten the death.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119709

DOI: 10.11138/ccmbm/2016.13.2.123
PubMed: 27920808
PubMed Central: 5119709

Affiliations:

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Risk factors of mortality during the first year after low energy osteoporosis fracture: a retrospective case-control study</title>
<author><name sortKey="Lloret, Aurore" sort="Lloret, Aurore" uniqKey="Lloret A" first="Aurore" last="Lloret">Aurore Lloret</name>
<affiliation wicri:level="1"><nlm:aff id="af1-123-126">Service de Rhumatologie, CHU de Rennes Hôpital Sud, Rennes, Cedex 2, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Rhumatologie, CHU de Rennes Hôpital Sud, Rennes, Cedex 2</wicri:regionArea>
<wicri:noRegion>Cedex 2</wicri:noRegion>
<wicri:noRegion>Cedex 2</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Coiffier, Guillaume" sort="Coiffier, Guillaume" uniqKey="Coiffier G" first="Guillaume" last="Coiffier">Guillaume Coiffier</name>
<affiliation wicri:level="1"><nlm:aff id="af1-123-126">Service de Rhumatologie, CHU de Rennes Hôpital Sud, Rennes, Cedex 2, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Rhumatologie, CHU de Rennes Hôpital Sud, Rennes, Cedex 2</wicri:regionArea>
<wicri:noRegion>Cedex 2</wicri:noRegion>
<wicri:noRegion>Cedex 2</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Couchouron, Tiffen" sort="Couchouron, Tiffen" uniqKey="Couchouron T" first="Tiffen" last="Couchouron">Tiffen Couchouron</name>
<affiliation wicri:level="1"><nlm:aff id="af1-123-126">Service de Rhumatologie, CHU de Rennes Hôpital Sud, Rennes, Cedex 2, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Rhumatologie, CHU de Rennes Hôpital Sud, Rennes, Cedex 2</wicri:regionArea>
<wicri:noRegion>Cedex 2</wicri:noRegion>
<wicri:noRegion>Cedex 2</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Perdriger, Aleth" sort="Perdriger, Aleth" uniqKey="Perdriger A" first="Aleth" last="Perdriger">Aleth Perdriger</name>
<affiliation wicri:level="1"><nlm:aff id="af1-123-126">Service de Rhumatologie, CHU de Rennes Hôpital Sud, Rennes, Cedex 2, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Rhumatologie, CHU de Rennes Hôpital Sud, Rennes, Cedex 2</wicri:regionArea>
<wicri:noRegion>Cedex 2</wicri:noRegion>
<wicri:noRegion>Cedex 2</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Guggenbuhl, Pascal" sort="Guggenbuhl, Pascal" uniqKey="Guggenbuhl P" first="Pascal" last="Guggenbuhl">Pascal Guggenbuhl</name>
<affiliation wicri:level="1"><nlm:aff id="af1-123-126">Service de Rhumatologie, CHU de Rennes Hôpital Sud, Rennes, Cedex 2, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Rhumatologie, CHU de Rennes Hôpital Sud, Rennes, Cedex 2</wicri:regionArea>
<wicri:noRegion>Cedex 2</wicri:noRegion>
<wicri:noRegion>Cedex 2</wicri:noRegion>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="af2-123-126">INSERM UMR 991, Rennes, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM UMR 991, Rennes</wicri:regionArea>
<placeName><region type="region">Région Bretagne</region>
<region type="old region">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">27920808</idno>
<idno type="pmc">5119709</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119709</idno>
<idno type="RBID">PMC:5119709</idno>
<idno type="doi">10.11138/ccmbm/2016.13.2.123</idno>
<date when="2016">2016</date>
<idno type="wicri:Area/Pmc/Corpus">000445</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000445</idno>
<idno type="wicri:Area/Pmc/Curation">000442</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000442</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000029</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000029</idno>
<idno type="wicri:Area/Ncbi/Merge">001B72</idno>
<idno type="wicri:Area/Ncbi/Curation">001B72</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">001B72</idno>
<idno type="wicri:doubleKey">1724-8914:2016:Lloret A:risk:factors:of</idno>
<idno type="wicri:Area/Main/Merge">000170</idno>
<idno type="wicri:Area/Main/Curation">000169</idno>
<idno type="wicri:Area/Main/Exploration">000169</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Risk factors of mortality during the first year after low energy osteoporosis fracture: a retrospective case-control study</title>
<author><name sortKey="Lloret, Aurore" sort="Lloret, Aurore" uniqKey="Lloret A" first="Aurore" last="Lloret">Aurore Lloret</name>
<affiliation wicri:level="1"><nlm:aff id="af1-123-126">Service de Rhumatologie, CHU de Rennes Hôpital Sud, Rennes, Cedex 2, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Rhumatologie, CHU de Rennes Hôpital Sud, Rennes, Cedex 2</wicri:regionArea>
<wicri:noRegion>Cedex 2</wicri:noRegion>
<wicri:noRegion>Cedex 2</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Coiffier, Guillaume" sort="Coiffier, Guillaume" uniqKey="Coiffier G" first="Guillaume" last="Coiffier">Guillaume Coiffier</name>
<affiliation wicri:level="1"><nlm:aff id="af1-123-126">Service de Rhumatologie, CHU de Rennes Hôpital Sud, Rennes, Cedex 2, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Rhumatologie, CHU de Rennes Hôpital Sud, Rennes, Cedex 2</wicri:regionArea>
<wicri:noRegion>Cedex 2</wicri:noRegion>
<wicri:noRegion>Cedex 2</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Couchouron, Tiffen" sort="Couchouron, Tiffen" uniqKey="Couchouron T" first="Tiffen" last="Couchouron">Tiffen Couchouron</name>
<affiliation wicri:level="1"><nlm:aff id="af1-123-126">Service de Rhumatologie, CHU de Rennes Hôpital Sud, Rennes, Cedex 2, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Rhumatologie, CHU de Rennes Hôpital Sud, Rennes, Cedex 2</wicri:regionArea>
<wicri:noRegion>Cedex 2</wicri:noRegion>
<wicri:noRegion>Cedex 2</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Perdriger, Aleth" sort="Perdriger, Aleth" uniqKey="Perdriger A" first="Aleth" last="Perdriger">Aleth Perdriger</name>
<affiliation wicri:level="1"><nlm:aff id="af1-123-126">Service de Rhumatologie, CHU de Rennes Hôpital Sud, Rennes, Cedex 2, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Rhumatologie, CHU de Rennes Hôpital Sud, Rennes, Cedex 2</wicri:regionArea>
<wicri:noRegion>Cedex 2</wicri:noRegion>
<wicri:noRegion>Cedex 2</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Guggenbuhl, Pascal" sort="Guggenbuhl, Pascal" uniqKey="Guggenbuhl P" first="Pascal" last="Guggenbuhl">Pascal Guggenbuhl</name>
<affiliation wicri:level="1"><nlm:aff id="af1-123-126">Service de Rhumatologie, CHU de Rennes Hôpital Sud, Rennes, Cedex 2, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Service de Rhumatologie, CHU de Rennes Hôpital Sud, Rennes, Cedex 2</wicri:regionArea>
<wicri:noRegion>Cedex 2</wicri:noRegion>
<wicri:noRegion>Cedex 2</wicri:noRegion>
</affiliation>
<affiliation wicri:level="3"><nlm:aff id="af2-123-126">INSERM UMR 991, Rennes, France</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>INSERM UMR 991, Rennes</wicri:regionArea>
<placeName><region type="region">Région Bretagne</region>
<region type="old region">Région Bretagne</region>
<settlement type="city">Rennes</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j">Clinical Cases in Mineral and Bone Metabolism</title>
<idno type="ISSN">1724-8914</idno>
<idno type="eISSN">1971-3266</idno>
<imprint><date when="2016">2016</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><title>Summary</title>
<sec><title>Introduction</title>
<p>Osteoporotic fractures are a major public health problem because of the morbidity and mortality of fracture complications. The objective of this study was to examine predictive factors of mortality during the first year after an osteoporotic fracture.</p>
</sec>
<sec><title>Methods</title>
<p>It is a retrospective case-control study using data of a group of 1081 patients aged over 50 years with severe osteoporotic fractures by the Rennes university hospital emergency department from August 2007 to September 2008. Patients (cases) who died during the year following the fracture were compared with others who had survived (controls) one year after the fracture, matched on age, sex and type of fracture. Pre-fracture comorbidities and complications after the fractures were studied.</p>
</sec>
<sec><title>Results</title>
<p>Forty-two cases and 126 controls were analyzed without significant differences in age, sex or type of fracture. On univariate analysis, previous neoplasia, neurodegenerative disease, walking aids, thromboembolic complication, post fracture infection, post fracture heart failure, post fracture acute respiratory failure were associated with more mortality after osteoporotic fracture. After multivariate analysis, only previous neoplasia (OR = 4.63 [1.79 – 11.95]; p = 0.02) and acute respiratory failure after fracture (OR = 28.15 [5.75 – 137.9]; p<0.001) were retained as predictive factors during the year following the fracture.</p>
</sec>
<sec><title>Conclusion</title>
<p>Patients died more often from their co-morbidities than direct complications of their fractures. Osteoporotic fracture seems to be a marker of poor health status and a factor which may hasten the death.</p>
</sec>
</div>
</front>
</TEI>
<affiliations><list><country><li>France</li>
</country>
<region><li>Région Bretagne</li>
</region>
<settlement><li>Rennes</li>
</settlement>
</list>
<tree><country name="France"><noRegion><name sortKey="Lloret, Aurore" sort="Lloret, Aurore" uniqKey="Lloret A" first="Aurore" last="Lloret">Aurore Lloret</name>
</noRegion>
<name sortKey="Coiffier, Guillaume" sort="Coiffier, Guillaume" uniqKey="Coiffier G" first="Guillaume" last="Coiffier">Guillaume Coiffier</name>
<name sortKey="Couchouron, Tiffen" sort="Couchouron, Tiffen" uniqKey="Couchouron T" first="Tiffen" last="Couchouron">Tiffen Couchouron</name>
<name sortKey="Guggenbuhl, Pascal" sort="Guggenbuhl, Pascal" uniqKey="Guggenbuhl P" first="Pascal" last="Guggenbuhl">Pascal Guggenbuhl</name>
<name sortKey="Guggenbuhl, Pascal" sort="Guggenbuhl, Pascal" uniqKey="Guggenbuhl P" first="Pascal" last="Guggenbuhl">Pascal Guggenbuhl</name>
<name sortKey="Perdriger, Aleth" sort="Perdriger, Aleth" uniqKey="Perdriger A" first="Aleth" last="Perdriger">Aleth Perdriger</name>
</country>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000169 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000169 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Wicri/Sante
   |area=    ParkinsonFranceV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     PMC:5119709
   |texte=   Risk factors of mortality during the first year after low energy osteoporosis fracture: a retrospective case-control study
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:27920808" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a ParkinsonFranceV1

This area was generated with Dilib version V0.6.29.
Data generation: Wed May 17 19:46:39 2017. Site generation: Mon Mar 4 15:48:15 2024

La maladie de Parkinson en France (serveur d'exploration)

Risk factors of mortality during the first year after low energy osteoporosis fracture: a retrospective case-control study

Risk factors of mortality during the first year after low energy osteoporosis fracture: a retrospective case-control study

Source :

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	La maladie de Parkinson en France (serveur d'exploration)
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.