Performance of a bimanual load-lifting task by parkinsonian patients.
Identifieur interne : 005379 ( Main/Curation ); précédent : 005378; suivant : 005380Performance of a bimanual load-lifting task by parkinsonian patients.
Auteurs : F. Viallet [France] ; J. Massion [France] ; R. Massarino [France] ; R. Khalil [France]Source :
- Journal of Neurology, Neurosurgery & Psychiatry [ 0022-3050 ] ; 1987-10.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
- Aged, Antiparkinson Agents (pharmacology), Antiparkinson Agents (therapeutic use), Degenerative disease, Electromyography, Female, Functional Laterality (physiology), Hand, Human, Humans, Male, Middle Aged, Motor system disorder, Nervous system diseases, Parkinson Disease (drug therapy), Parkinson Disease (physiopathology), Parkinson disease, Posture, Psychomotor Performance (drug effects), Psychomotor Performance (physiology), Reaction Time.
- MESH :
- chemical , pharmacology : Antiparkinson Agents.
- chemical , therapeutic use : Antiparkinson Agents.
- drug effects : Psychomotor Performance.
- drug therapy : Parkinson Disease.
- physiology : Functional Laterality, Psychomotor Performance.
- physiopathology : Parkinson Disease.
- Aged, Electromyography, Female, Humans, Male, Middle Aged, Posture, Reaction Time.
Abstract
Normal subjects and Parkinsonian patients performed a bimanual load lifting task. In this task, one "postural" forearm, held in a horizontal position while supporting a 1 kg weight, was unloaded either by the experimenter's hand (imposed unloading) or by the subject's other hand in response to a tone burst (voluntary unloading). The variables recorded were reaction time (RT: time interval between the tone and beginning of unloading) and movement time (MT: duration of the change in force measured by a force platform on the "postural" forearm). Elbow angle changes were also measured with a potentiometer. The EMG activity from brachioradialis of the "postural" arm and that from the biceps of the "active" arm were recorded. The Parkinsonian patients showed an increase in both RT and MT and an impairment of the co-ordination between movement and posture which was reflected in an increase in amplitude of the elbow rotation after voluntary unloading. Moreover, the decrease in EMG activity in the brachioradialis of the postural arm during unloading was less in Parkinsonian patients than in the normal group. This disorder of postural command was often accompanied by a lack of anticipatory EMG changes. Comparison between treated and non-treated patients showed that dopamine agonists brought about recovery of both RT and MT but did not improve postural co-ordination. The co-ordination was less impaired when the voluntary unloading was performed by the preferred hand. Several hypotheses are discussed concerning the mechanism underlying this impaired co-ordination.
Url:
- https://api.istex.fr/document/BBEA07A6A0121909F9AD3B30499D414BEE44633B/fulltext/pdf
- http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1032450
DOI: 10.1136/jnnp.50.10.1274
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In this task, one "postural" forearm, held in a horizontal position while supporting a 1 kg weight, was unloaded either by the experimenter's hand (imposed unloading) or by the subject's other hand in response to a tone burst (voluntary unloading). The variables recorded were reaction time (RT: time interval between the tone and beginning of unloading) and movement time (MT: duration of the change in force measured by a force platform on the "postural" forearm). Elbow angle changes were also measured with a potentiometer. The EMG activity from brachioradialis of the "postural" arm and that from the biceps of the "active" arm were recorded. The Parkinsonian patients showed an increase in both RT and MT and an impairment of the co-ordination between movement and posture which was reflected in an increase in amplitude of the elbow rotation after voluntary unloading. Moreover, the decrease in EMG activity in the brachioradialis of the postural arm during unloading was less in Parkinsonian patients than in the normal group. This disorder of postural command was often accompanied by a lack of anticipatory EMG changes. Comparison between treated and non-treated patients showed that dopamine agonists brought about recovery of both RT and MT but did not improve postural co-ordination. The co-ordination was less impaired when the voluntary unloading was performed by the preferred hand. Several hypotheses are discussed concerning the mechanism underlying this impaired co-ordination.</div></front></TEI><double idat="0022-3050:1987:Viallet F:performance:of:a"><INIST><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Performance of a bimanual load-lifting task by Parkinsonian patients</title><author><name sortKey="Viallet, F" sort="Viallet, F" uniqKey="Viallet F" first="F." last="Viallet">F. Viallet</name></author><author><name sortKey="Massion, J" sort="Massion, J" uniqKey="Massion J" first="J." last="Massion">J. Massion</name></author><author><name sortKey="Massarino, R" sort="Massarino, R" uniqKey="Massarino R" first="R." last="Massarino">R. Massarino</name></author><author><name sortKey="Khalil, R" sort="Khalil, R" uniqKey="Khalil R" first="R." last="Khalil">R. Khalil</name></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">88-0047292</idno><date when="1987">1987</date><idno type="stanalyst">PASCAL 88-0047292 INIST</idno><idno type="RBID">Pascal:88-0047292</idno><idno type="wicri:Area/PascalFrancis/Corpus">001D04</idno><idno type="wicri:Area/PascalFrancis/Curation">001347</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">001B54</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">001B54</idno><idno type="wicri:doubleKey">0022-3050:1987:Viallet F:performance:of:a</idno><idno type="wicri:Area/Main/Merge">005F39</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Performance of a bimanual load-lifting task by Parkinsonian patients</title><author><name sortKey="Viallet, F" sort="Viallet, F" uniqKey="Viallet F" first="F." last="Viallet">F. Viallet</name></author><author><name sortKey="Massion, J" sort="Massion, J" uniqKey="Massion J" first="J." last="Massion">J. Massion</name></author><author><name sortKey="Massarino, R" sort="Massarino, R" uniqKey="Massarino R" first="R." last="Massarino">R. Massarino</name></author><author><name sortKey="Khalil, R" sort="Khalil, R" uniqKey="Khalil R" first="R." last="Khalil">R. Khalil</name></author></analytic><series><title level="j" type="main">Journal of Neurology Neurosurgery and Psychiatry</title><title level="j" type="abbreviated">J. Neurol. Neurosurg. Psychiatry</title><idno type="ISSN">0022-3050</idno><imprint><date when="1987">1987</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Journal of Neurology Neurosurgery and Psychiatry</title><title level="j" type="abbreviated">J. Neurol. Neurosurg. Psychiatry</title><idno type="ISSN">0022-3050</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Degenerative disease</term><term>Hand</term><term>Human</term><term>Motor system disorder</term><term>Nervous system diseases</term><term>Parkinson disease</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Parkinson maladie</term><term>Main</term><term>Trouble moteur</term><term>Maladie dégénérative</term><term>Système nerveux pathologie</term><term>Homme</term><term>Soulèvement poids</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="fr">Le trouble de la commande posturale est souvent accompagné d'une perte des modifications électromyographiques anticipées. La comparaison de malades traités et non traités montre que les agonistes de la dopamine permettent la récupération du temps de réaction et du temps de mouvement mais n'améliorent pas la coordination posturale</div></front></TEI></INIST><ISTEX><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Performance of a bimanual load-lifting task by parkinsonian patients.</title><author><name sortKey="Viallet, F" sort="Viallet, F" uniqKey="Viallet F" first="F" last="Viallet">F. Viallet</name></author><author><name sortKey="Massion, J" sort="Massion, J" uniqKey="Massion J" first="J" last="Massion">J. Massion</name></author><author><name sortKey="Massarino, R" sort="Massarino, R" uniqKey="Massarino R" first="R" last="Massarino">R. Massarino</name></author><author><name sortKey="Khalil, R" sort="Khalil, R" uniqKey="Khalil R" first="R" last="Khalil">R. Khalil</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:BBEA07A6A0121909F9AD3B30499D414BEE44633B</idno><date when="1987" year="1987">1987</date><idno type="doi">10.1136/jnnp.50.10.1274</idno><idno type="url">https://api.istex.fr/document/BBEA07A6A0121909F9AD3B30499D414BEE44633B/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">002426</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002426</idno><idno type="wicri:Area/Istex/Curation">002424</idno><idno type="wicri:Area/Istex/Checkpoint">002057</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">002057</idno><idno type="wicri:doubleKey">0022-3050:1987:Viallet F:performance:of:a</idno><idno type="wicri:Area/Main/Merge">005E99</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Performance of a bimanual load-lifting task by parkinsonian patients.</title><author><name sortKey="Viallet, F" sort="Viallet, F" uniqKey="Viallet F" first="F" last="Viallet">F. Viallet</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Service de Neurologie, CHU La Timone, Marseille</wicri:regionArea><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Massion, J" sort="Massion, J" uniqKey="Massion J" first="J" last="Massion">J. Massion</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Service de Neurologie, CHU La Timone, Marseille</wicri:regionArea><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Massarino, R" sort="Massarino, R" uniqKey="Massarino R" first="R" last="Massarino">R. Massarino</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Service de Neurologie, CHU La Timone, Marseille</wicri:regionArea><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author><author><name sortKey="Khalil, R" sort="Khalil, R" uniqKey="Khalil R" first="R" last="Khalil">R. Khalil</name><affiliation wicri:level="3"><country xml:lang="fr">France</country><wicri:regionArea>Service de Neurologie, CHU La Timone, Marseille</wicri:regionArea><placeName><region type="region">Provence-Alpes-Côte d'Azur</region><region type="old region">Provence-Alpes-Côte d'Azur</region><settlement type="city">Marseille</settlement></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Neurology, Neurosurgery & Psychiatry</title><title level="j" type="abbrev">J Neurol Neurosurg Psychiatry</title><idno type="ISSN">0022-3050</idno><idno type="eISSN">1468-330X</idno><imprint><publisher>BMJ Publishing Group Ltd</publisher><date type="published" when="1987-10">1987-10</date><biblScope unit="volume">50</biblScope><biblScope unit="issue">10</biblScope><biblScope unit="page" from="1274">1274</biblScope></imprint><idno type="ISSN">0022-3050</idno></series><idno type="istex">BBEA07A6A0121909F9AD3B30499D414BEE44633B</idno><idno type="DOI">10.1136/jnnp.50.10.1274</idno><idno type="href">jnnp-50-1274.pdf</idno><idno type="PMID">3681306</idno><idno type="local">jnnp;50/10/1274</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0022-3050</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Normal subjects and Parkinsonian patients performed a bimanual load lifting task. In this task, one "postural" forearm, held in a horizontal position while supporting a 1 kg weight, was unloaded either by the experimenter's hand (imposed unloading) or by the subject's other hand in response to a tone burst (voluntary unloading). The variables recorded were reaction time (RT: time interval between the tone and beginning of unloading) and movement time (MT: duration of the change in force measured by a force platform on the "postural" forearm). Elbow angle changes were also measured with a potentiometer. The EMG activity from brachioradialis of the "postural" arm and that from the biceps of the "active" arm were recorded. The Parkinsonian patients showed an increase in both RT and MT and an impairment of the co-ordination between movement and posture which was reflected in an increase in amplitude of the elbow rotation after voluntary unloading. Moreover, the decrease in EMG activity in the brachioradialis of the postural arm during unloading was less in Parkinsonian patients than in the normal group. This disorder of postural command was often accompanied by a lack of anticipatory EMG changes. Comparison between treated and non-treated patients showed that dopamine agonists brought about recovery of both RT and MT but did not improve postural co-ordination. The co-ordination was less impaired when the voluntary unloading was performed by the preferred hand. Several hypotheses are discussed concerning the mechanism underlying this impaired co-ordination.</div></front></TEI></ISTEX><PMC><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Performance of a bimanual load-lifting task by parkinsonian patients.</title><author><name sortKey="Viallet, F" sort="Viallet, F" uniqKey="Viallet F" first="F" last="Viallet">F. Viallet</name></author><author><name sortKey="Massion, J" sort="Massion, J" uniqKey="Massion J" first="J" last="Massion">J. Massion</name></author><author><name sortKey="Massarino, R" sort="Massarino, R" uniqKey="Massarino R" first="R" last="Massarino">R. Massarino</name></author><author><name sortKey="Khalil, R" sort="Khalil, R" uniqKey="Khalil R" first="R" last="Khalil">R. Khalil</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">3681306</idno><idno type="pmc">1032450</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1032450</idno><idno type="RBID">PMC:1032450</idno><date when="1987">1987</date><idno type="wicri:Area/Pmc/Corpus">000284</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000284</idno><idno type="wicri:Area/Pmc/Curation">000282</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000282</idno><idno type="wicri:Area/Pmc/Checkpoint">000986</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000986</idno><idno type="wicri:source">PubMed</idno><idno type="wicri:Area/PubMed/Corpus">001874</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001874</idno><idno type="wicri:Area/PubMed/Curation">001833</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001833</idno><idno type="wicri:Area/PubMed/Checkpoint">001833</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001833</idno><idno type="wicri:Area/Ncbi/Merge">001C48</idno><idno type="wicri:Area/Ncbi/Curation">001C48</idno><idno type="wicri:Area/Ncbi/Checkpoint">001C48</idno><idno type="wicri:doubleKey">0022-3050:1987:Viallet F:performance:of:a</idno><idno type="wicri:Area/Main/Merge">005E63</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Performance of a bimanual load-lifting task by parkinsonian patients.</title><author><name sortKey="Viallet, F" sort="Viallet, F" uniqKey="Viallet F" first="F" last="Viallet">F. Viallet</name></author><author><name sortKey="Massion, J" sort="Massion, J" uniqKey="Massion J" first="J" last="Massion">J. Massion</name></author><author><name sortKey="Massarino, R" sort="Massarino, R" uniqKey="Massarino R" first="R" last="Massarino">R. Massarino</name></author><author><name sortKey="Khalil, R" sort="Khalil, R" uniqKey="Khalil R" first="R" last="Khalil">R. Khalil</name></author></analytic><series><title level="j">Journal of Neurology, Neurosurgery, and Psychiatry</title><idno type="ISSN">0022-3050</idno><idno type="eISSN">1468-330X</idno><imprint><date when="1987">1987</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Antiparkinson Agents (pharmacology)</term><term>Antiparkinson Agents (therapeutic use)</term><term>Electromyography</term><term>Female</term><term>Functional Laterality (physiology)</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Parkinson Disease (drug therapy)</term><term>Parkinson Disease (physiopathology)</term><term>Posture</term><term>Psychomotor Performance (drug effects)</term><term>Psychomotor Performance (physiology)</term><term>Reaction Time</term></keywords><keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Antiparkinson Agents</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiparkinson Agents</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Psychomotor Performance</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Functional Laterality</term><term>Psychomotor Performance</term></keywords><keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Electromyography</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Posture</term><term>Reaction Time</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Normal subjects and Parkinsonian patients performed a bimanual load lifting task. In this task, one "postural" forearm, held in a horizontal position while supporting a 1 kg weight, was unloaded either by the experimenter's hand (imposed unloading) or by the subject's other hand in response to a tone burst (voluntary unloading). The variables recorded were reaction time (RT: time interval between the tone and beginning of unloading) and movement time (MT: duration of the change in force measured by a force platform on the "postural" forearm). Elbow angle changes were also measured with a potentiometer. The EMG activity from brachioradialis of the "postural" arm and that from the biceps of the "active" arm were recorded. The Parkinsonian patients showed an increase in both RT and MT and an impairment of the co-ordination between movement and posture which was reflected in an increase in amplitude of the elbow rotation after voluntary unloading. Moreover, the decrease in EMG activity in the brachioradialis of the postural arm during unloading was less in Parkinsonian patients than in the normal group. This disorder of postural command was often accompanied by a lack of anticipatory EMG changes. Comparison between treated and non-treated patients showed that dopamine agonists brought about recovery of both RT and MT but did not improve postural co-ordination. The co-ordination was less impaired when the voluntary unloading was performed by the preferred hand. Several hypotheses are discussed concerning the mechanism underlying this impaired co-ordination.</p></div></front></TEI></PMC></double></record>Pour manipuler ce document sous Unix (Dilib)
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