ParkinsonFranceV1, Main, Curation, bibRecord, 003E77

Worsening of levodopa-induced dyskinesias by motor and mental tasks

Identifieur interne : 003E77 ( Main/Curation ); précédent : 003E76; suivant : 003E78

Worsening of levodopa-induced dyskinesias by motor and mental tasks

Auteurs : F. Durif [France] ; M. Vidailhet [France] ; B. Debilly [France] ; Yves Agid [France]

Source :

Movement disorders [ 0885-3185 ] ; 1999.

RBID : Pascal:99-0186192

Descripteurs français

Pascal (Inist)
- Parkinson maladie, Dyskinésie, Tâche manuelle, Activité mentale, Activation, Exploration, Homme.
Wicri :
- topic : Homme.

English descriptors

KwdEn :
- Activation, Analysis of Variance, Antiparkinson Agents (adverse effects), Apomorphine, Dyskinesia, Dyskinesia, Drug-Induced (diagnosis), Dyskinesia, Drug-Induced (etiology), Dyskinesia, Drug-Induced (physiopathology), Exploration, Female, Human, Humans, Levodopa (adverse effects), Male, Manual task, Mental activity, Middle Aged, Motor Activity (physiology), Parkinson Disease (drug therapy), Parkinson Disease (physiopathology), Parkinson disease, Problem Solving (physiology), Severity of Illness Index, Speech (physiology), Volition (physiology).
MESH :
- chemical , adverse effects : Antiparkinson Agents, Levodopa.
- diagnosis : Dyskinesia, Drug-Induced.
- drug therapy : Parkinson Disease.
- etiology : Dyskinesia, Drug-Induced.
- physiology : Motor Activity, Problem Solving, Speech, Volition.
- physiopathology : Dyskinesia, Drug-Induced, Parkinson Disease.
- Analysis of Variance, Apomorphine, Female, Humans, Male, Middle Aged, Severity of Illness Index.

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Links to Exploration step

Pascal:99-0186192

Le document en format XML

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<sourceDesc><biblStruct><analytic><title xml:lang="en">Worsening of levodopa-induced dyskinesias by motor and mental tasks.</title>
<author><name sortKey="Durif, F" sort="Durif, F" uniqKey="Durif F" first="F" last="Durif">F. Durif</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Neurology, Fédération de Neurologie, CHU Clermont-Ferrand, France.</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Department of Neurology, Fédération de Neurologie, CHU Clermont-Ferrand</wicri:regionArea>
<wicri:noRegion>CHU Clermont-Ferrand</wicri:noRegion>
<wicri:noRegion>CHU Clermont-Ferrand</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Vidailhet, M" sort="Vidailhet, M" uniqKey="Vidailhet M" first="M" last="Vidailhet">M. Vidailhet</name>
</author>
<author><name sortKey="Debilly, B" sort="Debilly, B" uniqKey="Debilly B" first="B" last="Debilly">B. Debilly</name>
</author>
<author><name sortKey="Agid, Y" sort="Agid, Y" uniqKey="Agid Y" first="Y" last="Agid">Yves Agid</name>
<affiliation><country>France</country>
<placeName><settlement type="city">Paris</settlement>
<region type="region" nuts="2">Île-de-France</region>
</placeName>
<orgName type="hospital" n="4">Hôpital de la Salpêtrière</orgName>
<country>France</country>
<placeName><settlement type="city">Paris</settlement>
<region type="region" nuts="2">Île-de-France</region>
</placeName>
<orgName type="hospital" n="4">Hôpital de la Salpêtrière</orgName>
</affiliation>
</author>
</analytic>
<series><title level="j">Movement disorders : official journal of the Movement Disorder Society</title>
<idno type="ISSN">0885-3185</idno>
<imprint><date when="1999" type="published">1999</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Analysis of Variance</term>
<term>Antiparkinson Agents (adverse effects)</term>
<term>Apomorphine</term>
<term>Dyskinesia, Drug-Induced (diagnosis)</term>
<term>Dyskinesia, Drug-Induced (etiology)</term>
<term>Dyskinesia, Drug-Induced (physiopathology)</term>
<term>Female</term>
<term>Humans</term>
<term>Levodopa (adverse effects)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Motor Activity (physiology)</term>
<term>Parkinson Disease (drug therapy)</term>
<term>Parkinson Disease (physiopathology)</term>
<term>Problem Solving (physiology)</term>
<term>Severity of Illness Index</term>
<term>Speech (physiology)</term>
<term>Volition (physiology)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Antiparkinson Agents</term>
<term>Levodopa</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Dyskinesia, Drug-Induced</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Dyskinesia, Drug-Induced</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Motor Activity</term>
<term>Problem Solving</term>
<term>Speech</term>
<term>Volition</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Dyskinesia, Drug-Induced</term>
<term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Analysis of Variance</term>
<term>Apomorphine</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Severity of Illness Index</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Ten patients who had Parkinson's disease with disabling dyskinesia were included in this study to evaluate the role of mental (mental calculation) and motor (flexion/extension of right fingers, flexion/extension of left fingers, flexion/extension of the neck, speaking aloud) tasks on the worsening of peak-dose dyskinesia following administration of an effective single dose of apomorphine. Compared with the score at rest (1.3+/-0.3), a significant aggravation of the dyskinesia score was observed during speaking aloud (5.2+/-1.1, p<0.05), movements of right (4.5+/-1.0, p<0.05) and left (3.7+/-0.8, p<0.05) fingers, movements of the neck (5.1+/-1.0, p<0.05), and mental calculation (3.1+/-1.0, p<0.05). These results suggest that activation tasks such as "speaking aloud" could be used for objective assessment of dyskinesia severity.</div>
</front>
</TEI>
</PubMed>
</double>
</record>

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	La maladie de Parkinson en France (serveur d'exploration)
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La maladie de Parkinson en France (serveur d'exploration)

Worsening of levodopa-induced dyskinesias by motor and mental tasks

Worsening of levodopa-induced dyskinesias by motor and mental tasks

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