Prevalence of parkinsonism and Parkinson's disease in Europe: the EUROPARKINSON Collaborative Study. European Community Concerted Action on the Epidemiology of Parkinson's disease.
Identifieur interne : 002072 ( Istex/Corpus ); précédent : 002071; suivant : 002073Prevalence of parkinsonism and Parkinson's disease in Europe: the EUROPARKINSON Collaborative Study. European Community Concerted Action on the Epidemiology of Parkinson's disease.
Auteurs : M C De Rijk ; C. Tzourio ; M M Breteler ; J F Dartigues ; L. Amaducci ; S. Lopez-Pousa ; J M Manubens-Bertran ; A. Alpérovitch ; W A RoccaSource :
- Journal of Neurology, Neurosurgery & Psychiatry [ 0022-3050 ] ; 1997-01.
Abstract
OBJECTIVES: To assess and compare the prevalence of parkinsonism and Parkinson's disease in five European populations that were surveyed with similar methodology and diagnostic criteria. METHODS: Joint analysis of five community surveys--Gironde (France), eight centres in Italy, Rotterdam (The Netherlands), Girona (Spain), and Pamplona (Spain)--in which subjects were screened in person for parkinsonism. Overall, these surveys comprised 14,636 participants aged 65 years or older. RESULTS: The overall prevalence (per 100 population), age adjusted to the 1991 European standard population, was 2.3 for parkinsonism and 1.6 for Parkinson's disease. The overall prevalence of parkinsonism for the age groups 65 to 69, 70 to 74, 75 to 79, 80 to 84, and 85 to 89 years was respectively, 0.9, 1.5, 3.7, 5.0, and 5.1. The corresponding age specific figures for Parkinson's disease were 0.6, 1.0, 2.7, 3.6, and 3.5. After adjusting for age and sex, the prevalence figures did not differ significantly across studies, except for the French study in which prevalence was lower. Prevalence was similar in men and women. Overall, 24% of the subjects with Parkinson's disease were newly detected through the surveys. CONCLUSIONS: Prevalence of both parkinsonism and Parkinson's disease increased with age, without significant differences between men and women. There was no convincing evidence for differences in prevalence across European countries. A substantial proportion of patients with Parkinson's disease went undetected in the general population.
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DOI: 10.1136/jnnp.62.1.10
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Tzourio</name><affiliation><mods:affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</mods:affiliation></affiliation></author><author><name sortKey="Breteler, M M" sort="Breteler, M M" uniqKey="Breteler M" first="M M" last="Breteler">M M Breteler</name><affiliation><mods:affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</mods:affiliation></affiliation></author><author><name sortKey="Dartigues, J F" sort="Dartigues, J F" uniqKey="Dartigues J" first="J F" last="Dartigues">J F Dartigues</name><affiliation><mods:affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</mods:affiliation></affiliation></author><author><name sortKey="Amaducci, L" sort="Amaducci, L" uniqKey="Amaducci L" first="L" last="Amaducci">L. Amaducci</name><affiliation><mods:affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</mods:affiliation></affiliation></author><author><name sortKey="Lopez Pousa, S" sort="Lopez Pousa, S" uniqKey="Lopez Pousa S" first="S" last="Lopez-Pousa">S. Lopez-Pousa</name><affiliation><mods:affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</mods:affiliation></affiliation></author><author><name sortKey="Manubens Bertran, J M" sort="Manubens Bertran, J M" uniqKey="Manubens Bertran J" first="J M" last="Manubens-Bertran">J M Manubens-Bertran</name><affiliation><mods:affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</mods:affiliation></affiliation></author><author><name sortKey="Alperovitch, A" sort="Alperovitch, A" uniqKey="Alperovitch A" first="A" last="Alpérovitch">A. Alpérovitch</name><affiliation><mods:affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</mods:affiliation></affiliation></author><author><name sortKey="Rocca, W A" sort="Rocca, W A" uniqKey="Rocca W" first="W A" last="Rocca">W A Rocca</name><affiliation><mods:affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:F8853F8FA8E01E2332AFB5F6B0D402260DBD25E7</idno><date when="1997" year="1997">1997</date><idno type="doi">10.1136/jnnp.62.1.10</idno><idno type="url">https://api.istex.fr/document/F8853F8FA8E01E2332AFB5F6B0D402260DBD25E7/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">002072</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">002072</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Prevalence of parkinsonism and Parkinson's disease in Europe: the EUROPARKINSON Collaborative Study. European Community Concerted Action on the Epidemiology of Parkinson's disease.</title><author><name sortKey="De Rijk, M C" sort="De Rijk, M C" uniqKey="De Rijk M" first="M C" last="De Rijk">M C De Rijk</name><affiliation><mods:affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</mods:affiliation></affiliation></author><author><name sortKey="Tzourio, C" sort="Tzourio, C" uniqKey="Tzourio C" first="C" last="Tzourio">C. Tzourio</name><affiliation><mods:affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</mods:affiliation></affiliation></author><author><name sortKey="Breteler, M M" sort="Breteler, M M" uniqKey="Breteler M" first="M M" last="Breteler">M M Breteler</name><affiliation><mods:affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</mods:affiliation></affiliation></author><author><name sortKey="Dartigues, J F" sort="Dartigues, J F" uniqKey="Dartigues J" first="J F" last="Dartigues">J F Dartigues</name><affiliation><mods:affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</mods:affiliation></affiliation></author><author><name sortKey="Amaducci, L" sort="Amaducci, L" uniqKey="Amaducci L" first="L" last="Amaducci">L. Amaducci</name><affiliation><mods:affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</mods:affiliation></affiliation></author><author><name sortKey="Lopez Pousa, S" sort="Lopez Pousa, S" uniqKey="Lopez Pousa S" first="S" last="Lopez-Pousa">S. Lopez-Pousa</name><affiliation><mods:affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</mods:affiliation></affiliation></author><author><name sortKey="Manubens Bertran, J M" sort="Manubens Bertran, J M" uniqKey="Manubens Bertran J" first="J M" last="Manubens-Bertran">J M Manubens-Bertran</name><affiliation><mods:affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</mods:affiliation></affiliation></author><author><name sortKey="Alperovitch, A" sort="Alperovitch, A" uniqKey="Alperovitch A" first="A" last="Alpérovitch">A. Alpérovitch</name><affiliation><mods:affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</mods:affiliation></affiliation></author><author><name sortKey="Rocca, W A" sort="Rocca, W A" uniqKey="Rocca W" first="W A" last="Rocca">W A Rocca</name><affiliation><mods:affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Journal of Neurology, Neurosurgery & Psychiatry</title><title level="j" type="abbrev">J Neurol Neurosurg Psychiatry</title><idno type="ISSN">0022-3050</idno><idno type="eISSN">1468-330X</idno><imprint><publisher>BMJ Publishing Group Ltd</publisher><date type="published" when="1997-01">1997-01</date><biblScope unit="volume">62</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="10">10</biblScope></imprint><idno type="ISSN">0022-3050</idno></series><idno type="istex">F8853F8FA8E01E2332AFB5F6B0D402260DBD25E7</idno><idno type="DOI">10.1136/jnnp.62.1.10</idno><idno type="href">jnnp-62-10.pdf</idno><idno type="PMID">9010393</idno><idno type="local">jnnp;62/1/10</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0022-3050</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">OBJECTIVES: To assess and compare the prevalence of parkinsonism and Parkinson's disease in five European populations that were surveyed with similar methodology and diagnostic criteria. METHODS: Joint analysis of five community surveys--Gironde (France), eight centres in Italy, Rotterdam (The Netherlands), Girona (Spain), and Pamplona (Spain)--in which subjects were screened in person for parkinsonism. Overall, these surveys comprised 14,636 participants aged 65 years or older. RESULTS: The overall prevalence (per 100 population), age adjusted to the 1991 European standard population, was 2.3 for parkinsonism and 1.6 for Parkinson's disease. The overall prevalence of parkinsonism for the age groups 65 to 69, 70 to 74, 75 to 79, 80 to 84, and 85 to 89 years was respectively, 0.9, 1.5, 3.7, 5.0, and 5.1. The corresponding age specific figures for Parkinson's disease were 0.6, 1.0, 2.7, 3.6, and 3.5. After adjusting for age and sex, the prevalence figures did not differ significantly across studies, except for the French study in which prevalence was lower. Prevalence was similar in men and women. Overall, 24% of the subjects with Parkinson's disease were newly detected through the surveys. CONCLUSIONS: Prevalence of both parkinsonism and Parkinson's disease increased with age, without significant differences between men and women. There was no convincing evidence for differences in prevalence across European countries. A substantial proportion of patients with Parkinson's disease went undetected in the general population.</div></front></TEI><istex><corpusName>bmj</corpusName><author><json:item><name>M C de Rijk</name><affiliations><json:string>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</json:string></affiliations></json:item><json:item><name>C Tzourio</name><affiliations><json:string>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</json:string></affiliations></json:item><json:item><name>M M Breteler</name><affiliations><json:string>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</json:string></affiliations></json:item><json:item><name>J F Dartigues</name><affiliations><json:string>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</json:string></affiliations></json:item><json:item><name>L Amaducci</name><affiliations><json:string>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</json:string></affiliations></json:item><json:item><name>S Lopez-Pousa</name><affiliations><json:string>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</json:string></affiliations></json:item><json:item><name>J M Manubens-Bertran</name><affiliations><json:string>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</json:string></affiliations></json:item><json:item><name>A Alpérovitch</name><affiliations><json:string>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</json:string></affiliations></json:item><json:item><name>W A Rocca</name><affiliations><json:string>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</json:string></affiliations></json:item></author><language><json:string>eng</json:string></language><originalGenre><json:string>research-article</json:string></originalGenre><abstract>OBJECTIVES: To assess and compare the prevalence of parkinsonism and Parkinson's disease in five European populations that were surveyed with similar methodology and diagnostic criteria. METHODS: Joint analysis of five community surveys--Gironde (France), eight centres in Italy, Rotterdam (The Netherlands), Girona (Spain), and Pamplona (Spain)--in which subjects were screened in person for parkinsonism. Overall, these surveys comprised 14,636 participants aged 65 years or older. RESULTS: The overall prevalence (per 100 population), age adjusted to the 1991 European standard population, was 2.3 for parkinsonism and 1.6 for Parkinson's disease. The overall prevalence of parkinsonism for the age groups 65 to 69, 70 to 74, 75 to 79, 80 to 84, and 85 to 89 years was respectively, 0.9, 1.5, 3.7, 5.0, and 5.1. The corresponding age specific figures for Parkinson's disease were 0.6, 1.0, 2.7, 3.6, and 3.5. After adjusting for age and sex, the prevalence figures did not differ significantly across studies, except for the French study in which prevalence was lower. Prevalence was similar in men and women. Overall, 24% of the subjects with Parkinson's disease were newly detected through the surveys. CONCLUSIONS: Prevalence of both parkinsonism and Parkinson's disease increased with age, without significant differences between men and women. There was no convincing evidence for differences in prevalence across European countries. A substantial proportion of patients with Parkinson's disease went undetected in the general population.</abstract><qualityIndicators><score>8.214</score><pdfVersion>1.3</pdfVersion><pdfPageSize>595.27 x 841.89 pts (A4)</pdfPageSize><refBibsNative>false</refBibsNative><keywordCount>0</keywordCount><abstractCharCount>1546</abstractCharCount><pdfWordCount>3490</pdfWordCount><pdfCharCount>26075</pdfCharCount><pdfPageCount>6</pdfPageCount><abstractWordCount>227</abstractWordCount></qualityIndicators><title>Prevalence of parkinsonism and Parkinson's disease in Europe: the EUROPARKINSON Collaborative Study. 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European Community Concerted Action on the Epidemiology of Parkinson's disease.</title><respStmt><resp>Références bibliographiques récupérées via GROBID</resp><name resp="ISTEX-API">ISTEX-API (INIST-CNRS)</name></respStmt></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>BMJ Publishing Group Ltd</publisher><availability><p>BMJ</p></availability><date>1997-01-01</date></publicationStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Prevalence of parkinsonism and Parkinson's disease in Europe: the EUROPARKINSON Collaborative Study. European Community Concerted Action on the Epidemiology of Parkinson's disease.</title><author xml:id="author-1"><persName><forename type="first">M C</forename><surname>de Rijk</surname></persName><affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</affiliation></author><author xml:id="author-2"><persName><forename type="first">C</forename><surname>Tzourio</surname></persName><affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</affiliation></author><author xml:id="author-3"><persName><forename type="first">M M</forename><surname>Breteler</surname></persName><affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</affiliation></author><author xml:id="author-4"><persName><forename type="first">J F</forename><surname>Dartigues</surname></persName><affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</affiliation></author><author xml:id="author-5"><persName><forename type="first">L</forename><surname>Amaducci</surname></persName><affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</affiliation></author><author xml:id="author-6"><persName><forename type="first">S</forename><surname>Lopez-Pousa</surname></persName><affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</affiliation></author><author xml:id="author-7"><persName><forename type="first">J M</forename><surname>Manubens-Bertran</surname></persName><affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</affiliation></author><author xml:id="author-8"><persName><forename type="first">A</forename><surname>Alpérovitch</surname></persName><affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</affiliation></author><author xml:id="author-9"><persName><forename type="first">W A</forename><surname>Rocca</surname></persName><affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</affiliation></author></analytic><monogr><title level="j">Journal of Neurology, Neurosurgery & Psychiatry</title><title level="j" type="abbrev">J Neurol Neurosurg Psychiatry</title><idno type="pISSN">0022-3050</idno><idno type="eISSN">1468-330X</idno><imprint><publisher>BMJ Publishing Group Ltd</publisher><date type="published" when="1997-01"></date><biblScope unit="volume">62</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="10">10</biblScope></imprint></monogr><idno type="istex">F8853F8FA8E01E2332AFB5F6B0D402260DBD25E7</idno><idno type="DOI">10.1136/jnnp.62.1.10</idno><idno type="href">jnnp-62-10.pdf</idno><idno type="PMID">9010393</idno><idno type="local">jnnp;62/1/10</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1997-01-01</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>OBJECTIVES: To assess and compare the prevalence of parkinsonism and Parkinson's disease in five European populations that were surveyed with similar methodology and diagnostic criteria. METHODS: Joint analysis of five community surveys--Gironde (France), eight centres in Italy, Rotterdam (The Netherlands), Girona (Spain), and Pamplona (Spain)--in which subjects were screened in person for parkinsonism. Overall, these surveys comprised 14,636 participants aged 65 years or older. RESULTS: The overall prevalence (per 100 population), age adjusted to the 1991 European standard population, was 2.3 for parkinsonism and 1.6 for Parkinson's disease. The overall prevalence of parkinsonism for the age groups 65 to 69, 70 to 74, 75 to 79, 80 to 84, and 85 to 89 years was respectively, 0.9, 1.5, 3.7, 5.0, and 5.1. The corresponding age specific figures for Parkinson's disease were 0.6, 1.0, 2.7, 3.6, and 3.5. After adjusting for age and sex, the prevalence figures did not differ significantly across studies, except for the French study in which prevalence was lower. Prevalence was similar in men and women. Overall, 24% of the subjects with Parkinson's disease were newly detected through the surveys. CONCLUSIONS: Prevalence of both parkinsonism and Parkinson's disease increased with age, without significant differences between men and women. There was no convincing evidence for differences in prevalence across European countries. A substantial proportion of patients with Parkinson's disease went undetected in the general population.</p></abstract></profileDesc><revisionDesc><change when="1997-01-01">Created</change><change when="1997-01">Published</change><change xml:id="refBibs-istex" who="#ISTEX-API" when="2017-01-19">References added</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/F8853F8FA8E01E2332AFB5F6B0D402260DBD25E7/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="corpus bmj" wicri:toSee="no header"><istex:xmlDeclaration>version="1.0" encoding="UTF-8" standalone="no"</istex:xmlDeclaration><istex:docType PUBLIC="-//NLM//DTD Journal Archiving and Interchange DTD v2.3 20070202//EN" URI="archivearticle.dtd" name="istex:docType"></istex:docType><istex:document><article article-type="research-article" xml:lang="EN"><front><journal-meta><journal-id journal-id-type="hwp">jnnp</journal-id><journal-id journal-id-type="nlm-ta">J Neurol Neurosurg Psychiatry</journal-id><journal-title>Journal of Neurology, Neurosurgery & Psychiatry</journal-title><abbrev-journal-title abbrev-type="publisher">J Neurol Neurosurg Psychiatry</abbrev-journal-title><issn pub-type="ppub">0022-3050</issn><issn pub-type="epub">1468-330X</issn><publisher><publisher-name>BMJ Publishing Group Ltd</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">9010393</article-id><article-id pub-id-type="other">jnnp;62/1/10</article-id><article-id pub-id-type="doi">10.1136/jnnp.62.1.10</article-id><article-id pub-id-type="other">10</article-id><article-id pub-id-type="other">jnnp.62.1.10</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>Prevalence of parkinsonism and Parkinson's disease in Europe: the EUROPARKINSON Collaborative Study. European Community Concerted Action on the Epidemiology of Parkinson's disease.</article-title></title-group><contrib-group><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>de Rijk</surname><given-names>M C</given-names></name></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Tzourio</surname><given-names>C</given-names></name></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Breteler</surname><given-names>M M</given-names></name></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Dartigues</surname><given-names>J F</given-names></name></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Amaducci</surname><given-names>L</given-names></name></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Lopez-Pousa</surname><given-names>S</given-names></name></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Manubens-Bertran</surname><given-names>J M</given-names></name></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Alpérovitch</surname><given-names>A</given-names></name></contrib><contrib contrib-type="author" xlink:type="simple"><name name-style="western"><surname>Rocca</surname><given-names>W A</given-names></name></contrib></contrib-group><aff>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</aff><pub-date pub-type="ppub"><month>1</month><year>1997</year></pub-date><pub-date pub-type="epub"><day>1</day><month>1</month><year>1997</year></pub-date><volume>62</volume><volume-id pub-id-type="other">62</volume-id><volume-id pub-id-type="other">62</volume-id><issue>1</issue><issue-id pub-id-type="other">jnnp;62/1</issue-id><issue-id pub-id-type="other">1</issue-id><issue-id pub-id-type="other">62/1</issue-id><fpage>10</fpage><self-uri content-type="pdf" xlink:role="full-text" xlink:href="jnnp-62-10.pdf"></self-uri><abstract><p>OBJECTIVES: To assess and compare the prevalence of parkinsonism and Parkinson's disease in five European populations that were surveyed with similar methodology and diagnostic criteria. METHODS: Joint analysis of five community surveys--Gironde (France), eight centres in Italy, Rotterdam (The Netherlands), Girona (Spain), and Pamplona (Spain)--in which subjects were screened in person for parkinsonism. Overall, these surveys comprised 14,636 participants aged 65 years or older. RESULTS: The overall prevalence (per 100 population), age adjusted to the 1991 European standard population, was 2.3 for parkinsonism and 1.6 for Parkinson's disease. The overall prevalence of parkinsonism for the age groups 65 to 69, 70 to 74, 75 to 79, 80 to 84, and 85 to 89 years was respectively, 0.9, 1.5, 3.7, 5.0, and 5.1. The corresponding age specific figures for Parkinson's disease were 0.6, 1.0, 2.7, 3.6, and 3.5. After adjusting for age and sex, the prevalence figures did not differ significantly across studies, except for the French study in which prevalence was lower. Prevalence was similar in men and women. Overall, 24% of the subjects with Parkinson's disease were newly detected through the surveys. CONCLUSIONS: Prevalence of both parkinsonism and Parkinson's disease increased with age, without significant differences between men and women. There was no convincing evidence for differences in prevalence across European countries. A substantial proportion of patients with Parkinson's disease went undetected in the general population.</p></abstract></article-meta></front></article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Prevalence of parkinsonism and Parkinson's disease in Europe: the EUROPARKINSON Collaborative Study. European Community Concerted Action on the Epidemiology of Parkinson's disease.</title></titleInfo><titleInfo type="alternative" lang="en" contentType="CDATA"><title>Prevalence of parkinsonism and Parkinson's disease in Europe: the EUROPARKINSON Collaborative Study. European Community Concerted Action on the Epidemiology of Parkinson's disease.</title></titleInfo><name type="personal"><namePart type="given">M C</namePart><namePart type="family">de Rijk</namePart><affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">C</namePart><namePart type="family">Tzourio</namePart><affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M M</namePart><namePart type="family">Breteler</namePart><affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J F</namePart><namePart type="family">Dartigues</namePart><affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">L</namePart><namePart type="family">Amaducci</namePart><affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">S</namePart><namePart type="family">Lopez-Pousa</namePart><affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">J M</namePart><namePart type="family">Manubens-Bertran</namePart><affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">A</namePart><namePart type="family">Alpérovitch</namePart><affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">W A</namePart><namePart type="family">Rocca</namePart><affiliation>Department of Epidemiology and Biostatistics, Erasmus University Medical School, Rotterdam, The Netherlands.</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="research-article"></genre><originInfo><publisher>BMJ Publishing Group Ltd</publisher><dateIssued encoding="w3cdtf">1997-01</dateIssued><dateCreated encoding="w3cdtf">1997-01-01</dateCreated><copyrightDate encoding="w3cdtf">1997</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">OBJECTIVES: To assess and compare the prevalence of parkinsonism and Parkinson's disease in five European populations that were surveyed with similar methodology and diagnostic criteria. METHODS: Joint analysis of five community surveys--Gironde (France), eight centres in Italy, Rotterdam (The Netherlands), Girona (Spain), and Pamplona (Spain)--in which subjects were screened in person for parkinsonism. Overall, these surveys comprised 14,636 participants aged 65 years or older. RESULTS: The overall prevalence (per 100 population), age adjusted to the 1991 European standard population, was 2.3 for parkinsonism and 1.6 for Parkinson's disease. The overall prevalence of parkinsonism for the age groups 65 to 69, 70 to 74, 75 to 79, 80 to 84, and 85 to 89 years was respectively, 0.9, 1.5, 3.7, 5.0, and 5.1. The corresponding age specific figures for Parkinson's disease were 0.6, 1.0, 2.7, 3.6, and 3.5. After adjusting for age and sex, the prevalence figures did not differ significantly across studies, except for the French study in which prevalence was lower. Prevalence was similar in men and women. Overall, 24% of the subjects with Parkinson's disease were newly detected through the surveys. CONCLUSIONS: Prevalence of both parkinsonism and Parkinson's disease increased with age, without significant differences between men and women. There was no convincing evidence for differences in prevalence across European countries. A substantial proportion of patients with Parkinson's disease went undetected in the general population.</abstract><relatedItem type="host"><titleInfo><title>Journal of Neurology, Neurosurgery & Psychiatry</title></titleInfo><titleInfo type="abbreviated"><title>J Neurol Neurosurg Psychiatry</title></titleInfo><genre type="journal">journal</genre><identifier type="ISSN">0022-3050</identifier><identifier type="eISSN">1468-330X</identifier><identifier type="PublisherID-hwp">jnnp</identifier><identifier type="PublisherID-nlm-ta">J Neurol Neurosurg Psychiatry</identifier><part><date>1997</date><detail type="volume"><caption>vol.</caption><number>62</number></detail><detail type="issue"><caption>no.</caption><number>1</number></detail><extent unit="pages"><start>10</start></extent></part></relatedItem><identifier type="istex">F8853F8FA8E01E2332AFB5F6B0D402260DBD25E7</identifier><identifier type="DOI">10.1136/jnnp.62.1.10</identifier><identifier type="href">jnnp-62-10.pdf</identifier><identifier type="PMID">9010393</identifier><identifier type="local">jnnp;62/1/10</identifier><recordInfo><recordContentSource>BMJ</recordContentSource></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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