Effects of intracerebroventricular administration of aminophylline on hyperbaric-induced increase in carotid blood flow
Identifieur interne : 000F58 ( Istex/Corpus ); précédent : 000F57; suivant : 000F59Effects of intracerebroventricular administration of aminophylline on hyperbaric-induced increase in carotid blood flow
Auteurs : François Guerrero ; Henri BurnetSource :
- European Journal of Applied Physiology and Occupational Physiology [ 0301-5548 ] ; 1995-01-01.
Abstract
Abstract: Carotid blood flow was measured in rats by implanted transit-time ultrasonic flowprobes during hyperbaric experiments at up to 70 bar (7 MPa) using an helium-oxygen hyperoxic (partial pressure of O2 = 400 mbar) mixture. Before the hyperbaric experiment, an intracerebroventricular injection of phosphate saline buffered solution (PBS) or aminophylline, an adenosine receptor blocker, in PBS was given. Throughout the hyperbaric experiment carotid blood flow increased with ambient pressure in both PBS, i.e. control, and aminophylline treated rats. The increase in carotid blood flow was significantly attenuated in aminophylline treated rats. Additional experiments showed that the increased carotid blood flow was independent of hyperoxia as well as of temperature. The hypothesis that the hyperbaric dependent increase in carotid blood flow was mediated by brain adenosine receptors and its implication regarding a cerebral vasodilatation are discussed.
Url:
DOI: 10.1007/BF00511237
Links to Exploration step
ISTEX:23960377FE8C6CCCC679AC742FDD6A573AB534E1Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Effects of intracerebroventricular administration of aminophylline on hyperbaric-induced increase in carotid blood flow</title><author><name sortKey="Guerrero, Francois" sort="Guerrero, Francois" uniqKey="Guerrero F" first="François" last="Guerrero">François Guerrero</name><affiliation><mods:affiliation>Laboratoire de Physiopathologie Resporatoire-URA 1630 CNRS, Institut Jean Roche, Faculté de Médecine-Nord, Boulevard P. Dramard, F-13916, Marseille Cedex 20, France</mods:affiliation></affiliation></author><author><name sortKey="Burnet, Henri" sort="Burnet, Henri" uniqKey="Burnet H" first="Henri" last="Burnet">Henri Burnet</name><affiliation><mods:affiliation>Laboratoire de Physiopathologie Resporatoire-URA 1630 CNRS, Institut Jean Roche, Faculté de Médecine-Nord, Boulevard P. Dramard, F-13916, Marseille Cedex 20, France</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:23960377FE8C6CCCC679AC742FDD6A573AB534E1</idno><date when="1995" year="1995">1995</date><idno type="doi">10.1007/BF00511237</idno><idno type="url">https://api.istex.fr/document/23960377FE8C6CCCC679AC742FDD6A573AB534E1/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000F58</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000F58</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Effects of intracerebroventricular administration of aminophylline on hyperbaric-induced increase in carotid blood flow</title><author><name sortKey="Guerrero, Francois" sort="Guerrero, Francois" uniqKey="Guerrero F" first="François" last="Guerrero">François Guerrero</name><affiliation><mods:affiliation>Laboratoire de Physiopathologie Resporatoire-URA 1630 CNRS, Institut Jean Roche, Faculté de Médecine-Nord, Boulevard P. Dramard, F-13916, Marseille Cedex 20, France</mods:affiliation></affiliation></author><author><name sortKey="Burnet, Henri" sort="Burnet, Henri" uniqKey="Burnet H" first="Henri" last="Burnet">Henri Burnet</name><affiliation><mods:affiliation>Laboratoire de Physiopathologie Resporatoire-URA 1630 CNRS, Institut Jean Roche, Faculté de Médecine-Nord, Boulevard P. Dramard, F-13916, Marseille Cedex 20, France</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">European Journal of Applied Physiology and Occupational Physiology</title><title level="j" type="abbrev">Europ. J. Appl. Physiol.</title><idno type="ISSN">0301-5548</idno><idno type="eISSN">1439-6327</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>Berlin/Heidelberg</pubPlace><date type="published" when="1995-01-01">1995-01-01</date><biblScope unit="volume">71</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="87">87</biblScope><biblScope unit="page" to="94">94</biblScope></imprint><idno type="ISSN">0301-5548</idno></series><idno type="istex">23960377FE8C6CCCC679AC742FDD6A573AB534E1</idno><idno type="DOI">10.1007/BF00511237</idno><idno type="ArticleID">BF00511237</idno><idno type="ArticleID">Art10</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0301-5548</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Abstract: Carotid blood flow was measured in rats by implanted transit-time ultrasonic flowprobes during hyperbaric experiments at up to 70 bar (7 MPa) using an helium-oxygen hyperoxic (partial pressure of O2 = 400 mbar) mixture. Before the hyperbaric experiment, an intracerebroventricular injection of phosphate saline buffered solution (PBS) or aminophylline, an adenosine receptor blocker, in PBS was given. Throughout the hyperbaric experiment carotid blood flow increased with ambient pressure in both PBS, i.e. control, and aminophylline treated rats. The increase in carotid blood flow was significantly attenuated in aminophylline treated rats. Additional experiments showed that the increased carotid blood flow was independent of hyperoxia as well as of temperature. The hypothesis that the hyperbaric dependent increase in carotid blood flow was mediated by brain adenosine receptors and its implication regarding a cerebral vasodilatation are discussed.</div></front></TEI><istex><corpusName>springer</corpusName><author><json:item><name>François Guerrero</name><affiliations><json:string>Laboratoire de Physiopathologie Resporatoire-URA 1630 CNRS, Institut Jean Roche, Faculté de Médecine-Nord, Boulevard P. Dramard, F-13916, Marseille Cedex 20, France</json:string></affiliations></json:item><json:item><name>Henri Burnet</name><affiliations><json:string>Laboratoire de Physiopathologie Resporatoire-URA 1630 CNRS, Institut Jean Roche, Faculté de Médecine-Nord, Boulevard P. Dramard, F-13916, Marseille Cedex 20, France</json:string></affiliations></json:item></author><articleId><json:string>BF00511237</json:string><json:string>Art10</json:string></articleId><language><json:string>eng</json:string></language><originalGenre><json:string>OriginalPaper</json:string></originalGenre><abstract>Abstract: Carotid blood flow was measured in rats by implanted transit-time ultrasonic flowprobes during hyperbaric experiments at up to 70 bar (7 MPa) using an helium-oxygen hyperoxic (partial pressure of O2 = 400 mbar) mixture. Before the hyperbaric experiment, an intracerebroventricular injection of phosphate saline buffered solution (PBS) or aminophylline, an adenosine receptor blocker, in PBS was given. Throughout the hyperbaric experiment carotid blood flow increased with ambient pressure in both PBS, i.e. control, and aminophylline treated rats. The increase in carotid blood flow was significantly attenuated in aminophylline treated rats. Additional experiments showed that the increased carotid blood flow was independent of hyperoxia as well as of temperature. The hypothesis that the hyperbaric dependent increase in carotid blood flow was mediated by brain adenosine receptors and its implication regarding a cerebral vasodilatation are discussed.</abstract><qualityIndicators><score>6.153</score><pdfVersion>1.3</pdfVersion><pdfPageSize>598 x 785 pts</pdfPageSize><refBibsNative>false</refBibsNative><keywordCount>0</keywordCount><abstractCharCount>966</abstractCharCount><pdfWordCount>4533</pdfWordCount><pdfCharCount>27009</pdfCharCount><pdfPageCount>8</pdfPageCount><abstractWordCount>135</abstractWordCount></qualityIndicators><title>Effects of intracerebroventricular administration of aminophylline on hyperbaric-induced increase in carotid blood flow</title><refBibs><json:item><author><json:item><name>Jh Abraini</name></json:item><json:item><name>Jc Rostain</name></json:item></author><host><volume>40</volume><pages><last>310</last><first>305</first></pages><author></author><title>Pharmacol Biochem Behav</title><publicationDate>1991</publicationDate></host><title>Effects of administration of a-methylp-tyrosine on the striatal dopamine increase and the behavioral motor disturbances in rats exposed to high pressure</title><publicationDate>1991</publicationDate></json:item><json:item><author><json:item><name>Jh Abrain</name></json:item><json:item><name>M Ansseau</name></json:item><json:item><name>T Fechtali</name></json:item></author><host><volume>34</volume><pages><last>629</last><first>622</first></pages><author></author><title>Biol Psychiatry</title><publicationDate>1993</publicationDate></host><title>Pressure-induced disorders in neurotransmission and spontaneous behavior in rats: an animal model of psychosis</title><publicationDate>1993</publicationDate></json:item><json:item><author><json:item><name>Dt Beattie</name></json:item><json:item><name>He Connor</name></json:item></author><host><volume>112</volume><pages><last>266</last><first>262</first></pages><author></author><title>Br J Pharmacol</title><publicationDate>1994</publicationDate></host><title>The influence of the trigeminal ganglion on carotid blood flow in anesthetized guinea-pigs</title><publicationDate>1994</publicationDate></json:item><json:item><author><json:item><name>Pb Bennett</name></json:item><json:item><name>Jc Rostain</name></json:item></author><host><pages><last>237</last><first>194</first></pages><author></author><title>Physiology and medecine of diving</title><publicationDate>1993</publicationDate></host><title>The high pressure nervous syndrome</title><publicationDate>1993</publicationDate></json:item><json:item><author><json:item><name>Rm Berne</name></json:item><json:item><name>R Rubio</name></json:item><json:item><name>Br Curnish</name></json:item></author><host><volume>35</volume><pages><last>271</last><first>262</first></pages><author></author><title>Circ Res</title><publicationDate>1974</publicationDate></host><title>Release of adenosine from ischemic brain Effect on cerebral vascular resistance and incorporation into cerebral adenine nucleotides</title><publicationDate>1974</publicationDate></json:item><json:item><author><json:item><name>Rm Berne</name></json:item><json:item><name>Hr Winn</name></json:item><json:item><name>Rm Knabb</name></json:item><json:item><name>Sw Ely</name></json:item><json:item><name>R Rubio</name></json:item></author><host><pages><last>313</last><first>293</first></pages><author></author><title>Proceedings of the International Symposium on Adenosine</title><publicationDate>1982</publicationDate></host><title>Blood flow regulation by adenosine in heart, brain and skeletal muscle Developments in pharmacology 2: regulatory functions of adenosine</title><publicationDate>1982</publicationDate></json:item><json:item><author><json:item><name>Aa Buhlmann</name></json:item><json:item><name>M Matthys</name></json:item><json:item><name>G Overath</name></json:item><json:item><name>Pb Bennett</name></json:item><json:item><name>Dh Elliott</name></json:item><json:item><name>Sp Gray</name></json:item></author><host><volume>41</volume><pages><last>402</last><first>394</first></pages><author></author><title>Aerospace Med</title><publicationDate>1970</publicationDate></host><title>Saturation exposures at 31 ATA in an oxygenhelium atmosphere with excursions to 36 ATA</title><publicationDate>1970</publicationDate></json:item><json:item><author><json:item><name>Rg Burton</name></json:item><json:item><name>Rc Gorewitt</name></json:item></author><host><volume>15</volume><pages><last>73</last><first>68</first></pages><author></author><title>Med Electron</title><publicationDate>1984</publicationDate></host><title>Ultrasonic flowmeter use widebeam transit-time technique</title><publicationDate>1984</publicationDate></json:item><json:item><author><json:item><name>E Dora</name></json:item><json:item><name>A Koller</name></json:item><json:item><name>Agb Kovach</name></json:item></author><host><volume>4</volume><pages><last>457</last><first>447</first></pages><author></author><title>J. Cereb Blood Flow Metab</title><publicationDate>1984</publicationDate></host><title>Effect of topical adenosine deaminase treatment on the functional hyperemic and hypoxic responses of cerbrocortical microcirculation</title><publicationDate>1984</publicationDate></json:item><json:item><author><json:item><name>Nr Draper</name></json:item><json:item><name>H Smith</name></json:item></author><host><volume>58</volume><pages><last>145</last><first>141</first></pages><author></author><title>Eur J Appl Physiot</title><publicationDate>1966</publicationDate></host><title>Applied regression analysis Effects of high pressure on nervous conduction velocity in man</title><publicationDate>1966</publicationDate></json:item><json:item><host><author><json:item><name>R Hyacinthe</name></json:item><json:item><name>P Giry</name></json:item><json:item><name>R Broussolle</name></json:item></author><title>L'affinit6 de l'h6moglobine pur l'oxyg~ne en hyperbarie. In: Travaux scientifiques du service de sant6 des armies</title><publicationDate>1982</publicationDate></host></json:item><json:item><author><json:item><name>Kr Ko</name></json:item><json:item><name>Ac Ngai</name></json:item><json:item><name>Hr Winn</name></json:item></author><host><pages><last>1708</last><first>1703</first></pages><author></author><title>Am J Physiol</title><publicationDate>1990</publicationDate></host><title>Role of adenosine in regulation of regional cerebral blood flow in sensory cortex</title><publicationDate>1990</publicationDate></json:item><json:item><host><author><json:item><name>Jfr Ksnig</name></json:item><json:item><name>Ra Klippel</name></json:item></author><title>The rat brain: a stereotaxic atlas</title><publicationDate>1967</publicationDate></host></json:item><json:item><author><json:item><name>N Laudignon</name></json:item><json:item><name>E Farri</name></json:item><json:item><name>K Beharry</name></json:item><json:item><name>Rex,J Aranda</name></json:item><json:item><name>Jv </name></json:item></author><host><volume>68</volume><pages><last>1541</last><first>1534</first></pages><author></author><title>J Appl Physiol</title><publicationDate>1990</publicationDate></host><title>Influence of adenosine on cerebral blood flow during hypoxic hypoxia in the newborn piglet</title><publicationDate>1990</publicationDate></json:item><json:item><author><json:item><name>Merck Index Merck</name></json:item><json:item><name>N,J Rahway</name></json:item><json:item><name>S Morii</name></json:item><json:item><name>Ac Ngai</name></json:item><json:item><name>Kr Ko</name></json:item><json:item><name>Hr Winn</name></json:item></author><host><volume>253</volume><pages><last>175</last><first>165</first></pages><author></author><title>Am J Physiol</title><publicationDate>1987</publicationDate></host><title>Aminophylline Role of adenosine in regulation of cerebral blood flow: effects of theophylline during normoxia and hypoxia</title><publicationDate>1987</publicationDate></json:item><json:item><author><json:item><name>Tp Obrenovitch</name></json:item><json:item><name>Jl Gillard</name></json:item></author><host><volume>58</volume><pages><last>843</last><first>839</first></pages><author></author><title>J Appl Physiol</title><publicationDate>1985</publicationDate></host><title>Decreased brain levels of ascorbic acid in rats exposed to high pressures</title><publicationDate>1985</publicationDate></json:item><json:item><author></author><host><volume>98</volume><pages><last>384</last><first>381</first></pages><author></author><title>Arch Int Physiol Biochem</title><publicationDate>1990</publicationDate></host><title>Changes in heart function at high pressure</title><publicationDate>1990</publicationDate></json:item><json:item><author><json:item><name>Jw Phillis</name></json:item><json:item><name>Ph Wu</name></json:item></author><host><pages><last>437</last><first>419</first></pages><author></author><title>Proceedings of the International Symposium on Adenosine</title><publicationDate>1982</publicationDate></host><title>The role of adenosine in central neuromodulation Regulatory functions of adenosine</title><publicationDate>1982</publicationDate></json:item><json:item><author><json:item><name>R Rubio</name></json:item><json:item><name>Rm Berne</name></json:item></author><host><volume>25</volume><pages><last>415</last><first>407</first></pages><author></author><title>Circ Res</title><publicationDate>1969</publicationDate></host><title>Release of adenosine by the normal myocardium in dogs and its relationship to regulation of coronary resistance</title><publicationDate>1969</publicationDate></json:item><json:item><author><json:item><name>Ka Rudolphi</name></json:item><json:item><name>P Schubert</name></json:item><json:item><name>Fe Parkinson</name></json:item><json:item><name>Bb Fredholm</name></json:item></author><host><volume>4</volume><pages><last>369</last><first>346</first></pages><author></author><title>Cereborvasc Brain Metab Rev</title><publicationDate>1992</publicationDate></host><title>Adenosine and brain ischemia</title><publicationDate>1992</publicationDate></json:item><json:item><author><json:item><name>Vm Sciotti</name></json:item><json:item><name>Ts Park</name></json:item><json:item><name>Rm Berne</name></json:item><json:item><name>Dgl Van Wylen</name></json:item></author><host><volume>613</volume><pages><last>20</last><first>16</first></pages><author></author><title>Brain Res</title><publicationDate>1993</publicationDate></host><title>Changes in extracellular adenosine during chemical or electrical brain stimulation</title><publicationDate>1993</publicationDate></json:item><json:item><author><json:item><name>P Sebert</name></json:item><json:item><name>L Barthelemy</name></json:item></author><host><volume>62</volume><pages><last>357</last><first>349</first></pages><author></author><title>Respir Physiol</title><publicationDate>1985</publicationDate></host><title>Effects of high ambiant pressure per se, 101 atm on eel metabolism</title><publicationDate>1985</publicationDate></json:item><json:item><author><json:item><name>Gl Stiles</name></json:item></author><host><pages><last>165</last><first>161</first></pages><author></author><title>News Phys Sci</title><publicationDate>1991</publicationDate></host><title>Adenosine receptors: physiological regulation and biochemical mechanisms</title><publicationDate>1991</publicationDate></json:item><json:item><author><json:item><name>Jhgm Van Beek</name></json:item><json:item><name>A Berkenbosh</name></json:item><json:item><name>De Goede</name></json:item><json:item><name>J Oliever</name></json:item><json:item><name>Cn </name></json:item></author><host><volume>63</volume><pages><last>77</last><first>65</first></pages><author></author><title>Respir Physiol</title><publicationDate>1986</publicationDate></host><title>Response of vertebral and carotid blood flow to isocapnic changes in end-tidal oxygen tension</title><publicationDate>1986</publicationDate></json:item><json:item><host><pages><last>59</last><first>55</first></pages><author><json:item><name>M Wahl</name></json:item><json:item><name>W Kuschinsky</name></json:item></author><title>The dilatory action of adenosine on pial arteries of cats and its inhibition by theophylline. Pfliigers Arch</title><publicationDate>1976</publicationDate></host></json:item><json:item><author><json:item><name>Hr Winn</name></json:item><json:item><name>R Rubio</name></json:item><json:item><name>Rm Berne</name></json:item></author><host><volume>45</volume><pages><last>492</last><first>486</first></pages><author></author><title>Circ Res</title><publicationDate>1979</publicationDate></host><title>Brain adenosine production in the rat during 60 seconds of ischemia</title><publicationDate>1979</publicationDate></json:item><json:item><author><json:item><name>Hr Winn</name></json:item><json:item><name>R Rubio</name></json:item><json:item><name>Rm Berne</name></json:item></author><host><volume>241</volume><pages><last>242</last><first>235</first></pages><author></author><title>Am J Physiol</title><publicationDate>1981</publicationDate></host><title>Brain adenosine concentration during hypoxia in rats</title><publicationDate>1981</publicationDate></json:item></refBibs><genre><json:string>research-article</json:string></genre><host><volume>71</volume><pages><last>94</last><first>87</first></pages><issn><json:string>0301-5548</json:string></issn><issue>1</issue><subject><json:item><value>Human Physiology</value></json:item><json:item><value>Occupational Medicine/Industrial Medicine</value></json:item><json:item><value>Sports Medicine</value></json:item></subject><journalId><json:string>421</json:string></journalId><genre><json:string>journal</json:string></genre><language><json:string>unknown</json:string></language><eissn><json:string>1439-6327</json:string></eissn><title>European Journal of Applied Physiology and Occupational Physiology</title><publicationDate>1995</publicationDate><copyrightDate>1995</copyrightDate></host><categories><wos></wos><scienceMetrix><json:string>health sciences</json:string><json:string>clinical medicine</json:string><json:string>sport sciences</json:string></scienceMetrix></categories><publicationDate>1995</publicationDate><copyrightDate>1995</copyrightDate><doi><json:string>10.1007/BF00511237</json:string></doi><id>23960377FE8C6CCCC679AC742FDD6A573AB534E1</id><score>0.1341731</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/23960377FE8C6CCCC679AC742FDD6A573AB534E1/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/23960377FE8C6CCCC679AC742FDD6A573AB534E1/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/23960377FE8C6CCCC679AC742FDD6A573AB534E1/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a" type="main" xml:lang="en">Effects of intracerebroventricular administration of aminophylline on hyperbaric-induced increase in carotid blood flow</title><respStmt><resp>Références bibliographiques récupérées via GROBID</resp><name resp="ISTEX-API">ISTEX-API (INIST-CNRS)</name></respStmt><respStmt><resp>Références bibliographiques récupérées via GROBID</resp><name resp="ISTEX-API">ISTEX-API (INIST-CNRS)</name></respStmt></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>Springer-Verlag</publisher><pubPlace>Berlin/Heidelberg</pubPlace><availability><p>Springer-Verlag, 1995</p></availability><date>1995</date></publicationStmt><notesStmt><note>Original Article</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a" type="main" xml:lang="en">Effects of intracerebroventricular administration of aminophylline on hyperbaric-induced increase in carotid blood flow</title><author xml:id="author-1"><persName><forename type="first">François</forename><surname>Guerrero</surname></persName><affiliation>Laboratoire de Physiopathologie Resporatoire-URA 1630 CNRS, Institut Jean Roche, Faculté de Médecine-Nord, Boulevard P. Dramard, F-13916, Marseille Cedex 20, France</affiliation></author><author xml:id="author-2" corresp="yes"><persName><forename type="first">Henri</forename><surname>Burnet</surname></persName><affiliation>Laboratoire de Physiopathologie Resporatoire-URA 1630 CNRS, Institut Jean Roche, Faculté de Médecine-Nord, Boulevard P. Dramard, F-13916, Marseille Cedex 20, France</affiliation></author></analytic><monogr><title level="j">European Journal of Applied Physiology and Occupational Physiology</title><title level="j" type="abbrev">Europ. J. Appl. Physiol.</title><idno type="journal-ID">421</idno><idno type="pISSN">0301-5548</idno><idno type="eISSN">1439-6327</idno><idno type="issue-article-count">10</idno><idno type="volume-issue-count">6</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>Berlin/Heidelberg</pubPlace><date type="published" when="1995-01-01"></date><biblScope unit="volume">71</biblScope><biblScope unit="issue">1</biblScope><biblScope unit="page" from="87">87</biblScope><biblScope unit="page" to="94">94</biblScope></imprint></monogr><idno type="istex">23960377FE8C6CCCC679AC742FDD6A573AB534E1</idno><idno type="DOI">10.1007/BF00511237</idno><idno type="ArticleID">BF00511237</idno><idno type="ArticleID">Art10</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1995</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Abstract: Carotid blood flow was measured in rats by implanted transit-time ultrasonic flowprobes during hyperbaric experiments at up to 70 bar (7 MPa) using an helium-oxygen hyperoxic (partial pressure of O2 = 400 mbar) mixture. Before the hyperbaric experiment, an intracerebroventricular injection of phosphate saline buffered solution (PBS) or aminophylline, an adenosine receptor blocker, in PBS was given. Throughout the hyperbaric experiment carotid blood flow increased with ambient pressure in both PBS, i.e. control, and aminophylline treated rats. The increase in carotid blood flow was significantly attenuated in aminophylline treated rats. Additional experiments showed that the increased carotid blood flow was independent of hyperoxia as well as of temperature. The hypothesis that the hyperbaric dependent increase in carotid blood flow was mediated by brain adenosine receptors and its implication regarding a cerebral vasodilatation are discussed.</p></abstract><textClass><keywords scheme="Journal Subject"><list><head>Biomedicine</head><item><term>Human Physiology</term></item><item><term>Occupational Medicine/Industrial Medicine</term></item><item><term>Sports Medicine</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="1995-01-01">Published</change><change xml:id="refBibs-istex" who="#ISTEX-API" when="2016-11-22">References added</change><change xml:id="refBibs-istex" who="#ISTEX-API" when="2017-01-20">References added</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/23960377FE8C6CCCC679AC742FDD6A573AB534E1/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Springer, Publisher found" wicri:toSee="no header"><istex:xmlDeclaration>version="1.0" encoding="UTF-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//Springer-Verlag//DTD A++ V2.4//EN" URI="http://devel.springer.de/A++/V2.4/DTD/A++V2.4.dtd" name="istex:docType"></istex:docType><istex:document><Publisher><PublisherInfo><PublisherName>Springer-Verlag</PublisherName><PublisherLocation>Berlin/Heidelberg</PublisherLocation></PublisherInfo><Journal><JournalInfo JournalProductType="ArchiveJournal" NumberingStyle="Unnumbered"><JournalID>421</JournalID><JournalPrintISSN>0301-5548</JournalPrintISSN><JournalElectronicISSN>1439-6327</JournalElectronicISSN><JournalTitle>European Journal of Applied Physiology and Occupational Physiology</JournalTitle><JournalAbbreviatedTitle>Europ. J. Appl. Physiol.</JournalAbbreviatedTitle><JournalSubjectGroup><JournalSubject Type="Primary">Biomedicine</JournalSubject><JournalSubject Type="Secondary">Human Physiology</JournalSubject><JournalSubject Type="Secondary">Occupational Medicine/Industrial Medicine</JournalSubject><JournalSubject Type="Secondary">Sports Medicine</JournalSubject></JournalSubjectGroup></JournalInfo><Volume><VolumeInfo VolumeType="Regular" TocLevels="0"><VolumeIDStart>71</VolumeIDStart><VolumeIDEnd>71</VolumeIDEnd><VolumeIssueCount>6</VolumeIssueCount></VolumeInfo><Issue IssueType="Regular"><IssueInfo TocLevels="0"><IssueIDStart>1</IssueIDStart><IssueIDEnd>1</IssueIDEnd><IssueArticleCount>10</IssueArticleCount><IssueHistory><CoverDate><DateString>1995</DateString><Year>1995</Year><Month>1</Month></CoverDate></IssueHistory><IssueCopyright><CopyrightHolderName>Springer-Verlag</CopyrightHolderName><CopyrightYear>1995</CopyrightYear></IssueCopyright></IssueInfo><Article ID="Art10"><ArticleInfo Language="En" ArticleType="OriginalPaper" NumberingStyle="Unnumbered" TocLevels="0" ContainsESM="No"><ArticleID>BF00511237</ArticleID><ArticleDOI>10.1007/BF00511237</ArticleDOI><ArticleSequenceNumber>10</ArticleSequenceNumber><ArticleTitle Language="En">Effects of intracerebroventricular administration of aminophylline on hyperbaric-induced increase in carotid blood flow</ArticleTitle><ArticleCategory>Original Article</ArticleCategory><ArticleFirstPage>87</ArticleFirstPage><ArticleLastPage>94</ArticleLastPage><ArticleHistory><RegistrationDate><Year>2004</Year><Month>10</Month><Day>6</Day></RegistrationDate><Accepted><Year>1995</Year><Month>1</Month><Day>5</Day></Accepted></ArticleHistory><ArticleCopyright><CopyrightHolderName>Springer-Verlag</CopyrightHolderName><CopyrightYear>1995</CopyrightYear></ArticleCopyright><ArticleGrants Type="Regular"><MetadataGrant Grant="OpenAccess"></MetadataGrant><AbstractGrant Grant="OpenAccess"></AbstractGrant><BodyPDFGrant Grant="Restricted"></BodyPDFGrant><BodyHTMLGrant Grant="Restricted"></BodyHTMLGrant><BibliographyGrant Grant="Restricted"></BibliographyGrant><ESMGrant Grant="Restricted"></ESMGrant></ArticleGrants><ArticleContext><JournalID>421</JournalID><VolumeIDStart>71</VolumeIDStart><VolumeIDEnd>71</VolumeIDEnd><IssueIDStart>1</IssueIDStart><IssueIDEnd>1</IssueIDEnd></ArticleContext></ArticleInfo><ArticleHeader><AuthorGroup><Author AffiliationIDS="Aff1"><AuthorName DisplayOrder="Western"><GivenName>François</GivenName><FamilyName>Guerrero</FamilyName></AuthorName></Author><Author AffiliationIDS="Aff1" CorrespondingAffiliationID="Aff1"><AuthorName DisplayOrder="Western"><GivenName>Henri</GivenName><FamilyName>Burnet</FamilyName></AuthorName></Author><Affiliation ID="Aff1"><OrgDivision>Laboratoire de Physiopathologie Resporatoire-URA 1630 CNRS</OrgDivision><OrgName>Institut Jean Roche, Faculté de Médecine-Nord</OrgName><OrgAddress><Street>Boulevard P. Dramard</Street><Postcode>F-13916</Postcode><City>Marseille Cedex 20</City><Country>France</Country></OrgAddress></Affiliation></AuthorGroup><Abstract ID="Abs1" Language="En"><Heading>Abstract</Heading><Para>Carotid blood flow was measured in rats by implanted transit-time ultrasonic flowprobes during hyperbaric experiments at up to 70 bar (7 MPa) using an helium-oxygen hyperoxic (partial pressure of O<Subscript>2</Subscript> = 400 mbar) mixture. Before the hyperbaric experiment, an intracerebroventricular injection of phosphate saline buffered solution (PBS) or aminophylline, an adenosine receptor blocker, in PBS was given. Throughout the hyperbaric experiment carotid blood flow increased with ambient pressure in both PBS, i.e. control, and aminophylline treated rats. The increase in carotid blood flow was significantly attenuated in aminophylline treated rats. Additional experiments showed that the increased carotid blood flow was independent of hyperoxia as well as of temperature. The hypothesis that the hyperbaric dependent increase in carotid blood flow was mediated by brain adenosine receptors and its implication regarding a cerebral vasodilatation are discussed.</Para></Abstract><KeywordGroup Language="En"><Heading>Key words</Heading><Keyword>High ambient pressure</Keyword><Keyword>Carotid blood flow</Keyword><Keyword>Adenosine</Keyword><Keyword>Aminophylline</Keyword><Keyword>Hypoxia</Keyword></KeywordGroup></ArticleHeader><NoBody></NoBody></Article></Issue></Volume></Journal></Publisher></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Effects of intracerebroventricular administration of aminophylline on hyperbaric-induced increase in carotid blood flow</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Effects of intracerebroventricular administration of aminophylline on hyperbaric-induced increase in carotid blood flow</title></titleInfo><name type="personal"><namePart type="given">François</namePart><namePart type="family">Guerrero</namePart><affiliation>Laboratoire de Physiopathologie Resporatoire-URA 1630 CNRS, Institut Jean Roche, Faculté de Médecine-Nord, Boulevard P. Dramard, F-13916, Marseille Cedex 20, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal" displayLabel="corresp"><namePart type="given">Henri</namePart><namePart type="family">Burnet</namePart><affiliation>Laboratoire de Physiopathologie Resporatoire-URA 1630 CNRS, Institut Jean Roche, Faculté de Médecine-Nord, Boulevard P. Dramard, F-13916, Marseille Cedex 20, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="OriginalPaper"></genre><originInfo><publisher>Springer-Verlag</publisher><place><placeTerm type="text">Berlin/Heidelberg</placeTerm></place><dateIssued encoding="w3cdtf">1995-01-01</dateIssued><copyrightDate encoding="w3cdtf">1995</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">Abstract: Carotid blood flow was measured in rats by implanted transit-time ultrasonic flowprobes during hyperbaric experiments at up to 70 bar (7 MPa) using an helium-oxygen hyperoxic (partial pressure of O2 = 400 mbar) mixture. Before the hyperbaric experiment, an intracerebroventricular injection of phosphate saline buffered solution (PBS) or aminophylline, an adenosine receptor blocker, in PBS was given. Throughout the hyperbaric experiment carotid blood flow increased with ambient pressure in both PBS, i.e. control, and aminophylline treated rats. The increase in carotid blood flow was significantly attenuated in aminophylline treated rats. Additional experiments showed that the increased carotid blood flow was independent of hyperoxia as well as of temperature. The hypothesis that the hyperbaric dependent increase in carotid blood flow was mediated by brain adenosine receptors and its implication regarding a cerebral vasodilatation are discussed.</abstract><note>Original Article</note><relatedItem type="host"><titleInfo><title>European Journal of Applied Physiology and Occupational Physiology</title></titleInfo><titleInfo type="abbreviated"><title>Europ. J. Appl. Physiol.</title></titleInfo><genre type="journal" displayLabel="Archive Journal"></genre><originInfo><dateIssued encoding="w3cdtf">1995-01-01</dateIssued><copyrightDate encoding="w3cdtf">1995</copyrightDate></originInfo><subject><genre>Biomedicine</genre><topic>Human Physiology</topic><topic>Occupational Medicine/Industrial Medicine</topic><topic>Sports Medicine</topic></subject><identifier type="ISSN">0301-5548</identifier><identifier type="eISSN">1439-6327</identifier><identifier type="JournalID">421</identifier><identifier type="IssueArticleCount">10</identifier><identifier type="VolumeIssueCount">6</identifier><part><date>1995</date><detail type="volume"><number>71</number><caption>vol.</caption></detail><detail type="issue"><number>1</number><caption>no.</caption></detail><extent unit="pages"><start>87</start><end>94</end></extent></part><recordInfo><recordOrigin>Springer-Verlag, 1995</recordOrigin></recordInfo></relatedItem><identifier type="istex">23960377FE8C6CCCC679AC742FDD6A573AB534E1</identifier><identifier type="DOI">10.1007/BF00511237</identifier><identifier type="ArticleID">BF00511237</identifier><identifier type="ArticleID">Art10</identifier><accessCondition type="use and reproduction" contentType="copyright">Springer-Verlag, 1995</accessCondition><recordInfo><recordContentSource>SPRINGER</recordContentSource><recordOrigin>Springer-Verlag, 1995</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Sante/explor/ParkinsonFranceV1/Data/Istex/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000F58 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Istex/Corpus/biblio.hfd -nk 000F58 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Sante
|area= ParkinsonFranceV1
|flux= Istex
|étape= Corpus
|type= RBID
|clé= ISTEX:23960377FE8C6CCCC679AC742FDD6A573AB534E1
|texte= Effects of intracerebroventricular administration of aminophylline on hyperbaric-induced increase in carotid blood flow
}}
| This area was generated with Dilib version V0.6.29. |  |