A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)KAkt signalling
Identifieur interne : 000E84 ( Istex/Corpus ); précédent : 000E83; suivant : 000E85A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)KAkt signalling
Auteurs : Lara Fallon ; Catherine M. L. Blanger ; Amadou T. Corera ; Maria Kontogiannea ; Elsa Regan-Klapisz ; France Moreau ; Jarno Voortman ; Michael Haber ; Genevive Rouleau ; Thorhildur Thorarinsdottir ; Alexis Brice ; Paul M. P. Van Bergen En Henegouwen ; Edward A. FonSource :
- Nature Cell Biology [ 1465-7392 ] ; 2006-08.
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DOI: 10.1038/ncb1441
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<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)KAkt signalling</title><author><name sortKey="Fallon, Lara" sort="Fallon, Lara" uniqKey="Fallon L" first="Lara" last="Fallon">Lara Fallon</name><affiliation><mods:affiliation>Centre for Neuronal Survival and Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 2B4.</mods:affiliation></affiliation></author><author><name sortKey="Blanger, Catherine M L" sort="Blanger, Catherine M L" uniqKey="Blanger C" first="Catherine M. L." last="Blanger">Catherine M. L. Blanger</name><affiliation><mods:affiliation>Centre for Neuronal Survival and Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 2B4.</mods:affiliation></affiliation></author><author><name sortKey="Corera, Amadou T" sort="Corera, Amadou T" uniqKey="Corera A" first="Amadou T." last="Corera">Amadou T. Corera</name><affiliation><mods:affiliation>Centre for Neuronal Survival and Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 2B4.</mods:affiliation></affiliation></author><author><name sortKey="Kontogiannea, Maria" sort="Kontogiannea, Maria" uniqKey="Kontogiannea M" first="Maria" last="Kontogiannea">Maria Kontogiannea</name><affiliation><mods:affiliation>Centre for Neuronal Survival and Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 2B4.</mods:affiliation></affiliation></author><author><name sortKey="Regan Klapisz, Elsa" sort="Regan Klapisz, Elsa" uniqKey="Regan Klapisz E" first="Elsa" last="Regan-Klapisz">Elsa Regan-Klapisz</name><affiliation><mods:affiliation>Molecular Cell Biology, Institute of Biomembranes, Universiteit Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands.</mods:affiliation></affiliation></author><author><name sortKey="Moreau, France" sort="Moreau, France" uniqKey="Moreau F" first="France" last="Moreau">France Moreau</name><affiliation><mods:affiliation>Centre for Neuronal Survival and Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 2B4.</mods:affiliation></affiliation></author><author><name sortKey="Voortman, Jarno" sort="Voortman, Jarno" uniqKey="Voortman J" first="Jarno" last="Voortman">Jarno Voortman</name><affiliation><mods:affiliation>Molecular Cell Biology, Institute of Biomembranes, Universiteit Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands.</mods:affiliation></affiliation></author><author><name sortKey="Haber, Michael" sort="Haber, Michael" uniqKey="Haber M" first="Michael" last="Haber">Michael Haber</name><affiliation><mods:affiliation>Centre for Neuronal Survival and Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 2B4.</mods:affiliation></affiliation></author><author><name sortKey="Rouleau, Genevive" sort="Rouleau, Genevive" uniqKey="Rouleau G" first="Genevive" last="Rouleau">Genevive Rouleau</name><affiliation><mods:affiliation>Centre for Neuronal Survival and Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 2B4.</mods:affiliation></affiliation></author><author><name sortKey="Thorarinsdottir, Thorhildur" sort="Thorarinsdottir, Thorhildur" uniqKey="Thorarinsdottir T" first="Thorhildur" last="Thorarinsdottir">Thorhildur Thorarinsdottir</name><affiliation><mods:affiliation>Centre for Neuronal Survival and Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 2B4.</mods:affiliation></affiliation></author><author><name sortKey="Brice, Alexis" sort="Brice, Alexis" uniqKey="Brice A" first="Alexis" last="Brice">Alexis Brice</name><affiliation><mods:affiliation>INSERM U. 679 and Department of Genetics, Cytogenetics and Embryology, Goupe Hospitalier Piti-Salptrire, 47, Bd de l'Hpital 75651, Paris Cedex 13, France.</mods:affiliation></affiliation></author><author><name sortKey="Van Bergen En Henegouwen, Paul M P" sort="Van Bergen En Henegouwen, Paul M P" uniqKey="Van Bergen En Henegouwen P" first="Paul M. P." last="Van Bergen En Henegouwen">Paul M. P. Van Bergen En Henegouwen</name><affiliation><mods:affiliation>Molecular Cell Biology, Institute of Biomembranes, Universiteit Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands.</mods:affiliation></affiliation></author><author><name sortKey="Fon, Edward A" sort="Fon, Edward A" uniqKey="Fon E" first="Edward A." last="Fon">Edward A. Fon</name><affiliation><mods:affiliation>Centre for Neuronal Survival and Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 2B4.</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: ted.fon@mcgill.ca</mods:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:85B9C86E147A9BCFEC452EFEFC20061B8171059A</idno><date when="2006" year="2006">2006</date><idno type="doi">10.1038/ncb1441</idno><idno type="url">https://api.istex.fr/document/85B9C86E147A9BCFEC452EFEFC20061B8171059A/fulltext/pdf</idno><idno type="wicri:Area/Istex/Corpus">000E84</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000E84</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)KAkt signalling</title><author><name sortKey="Fallon, Lara" sort="Fallon, Lara" uniqKey="Fallon L" first="Lara" last="Fallon">Lara Fallon</name><affiliation><mods:affiliation>Centre for Neuronal Survival and Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 2B4.</mods:affiliation></affiliation></author><author><name sortKey="Blanger, Catherine M L" sort="Blanger, Catherine M L" uniqKey="Blanger C" first="Catherine M. L." last="Blanger">Catherine M. L. Blanger</name><affiliation><mods:affiliation>Centre for Neuronal Survival and Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 2B4.</mods:affiliation></affiliation></author><author><name sortKey="Corera, Amadou T" sort="Corera, Amadou T" uniqKey="Corera A" first="Amadou T." last="Corera">Amadou T. 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P." last="Van Bergen En Henegouwen">Paul M. P. Van Bergen En Henegouwen</name><affiliation><mods:affiliation>Molecular Cell Biology, Institute of Biomembranes, Universiteit Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands.</mods:affiliation></affiliation></author><author><name sortKey="Fon, Edward A" sort="Fon, Edward A" uniqKey="Fon E" first="Edward A." last="Fon">Edward A. Fon</name><affiliation><mods:affiliation>Centre for Neuronal Survival and Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 2B4.</mods:affiliation></affiliation><affiliation><mods:affiliation>E-mail: ted.fon@mcgill.ca</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Nature Cell Biology</title><idno type="ISSN">1465-7392</idno><idno type="eISSN">1476-4679</idno><imprint><publisher>Nature Publishing Group</publisher><date type="published" when="2006-08">2006-08</date><biblScope unit="volume">8</biblScope><biblScope unit="issue">8</biblScope><biblScope unit="page" from="834">834</biblScope><biblScope unit="page" to="842">842</biblScope></imprint><idno type="ISSN">1465-7392</idno></series><idno type="istex">85B9C86E147A9BCFEC452EFEFC20061B8171059A</idno><idno type="DOI">10.1038/ncb1441</idno><idno type="ArticleID">ncb1441</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1465-7392</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader></TEI><istex><corpusName>nature</corpusName><author><json:item><name>Lara Fallon</name><affiliations><json:string>Centre for Neuronal Survival and Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 2B4.</json:string></affiliations></json:item><json:item><name>Catherine M.L. 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Fon</name><affiliations><json:string>Centre for Neuronal Survival and Department of Neurology & Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 2B4.</json:string><json:string>E-mail: ted.fon@mcgill.ca</json:string></affiliations></json:item></author><articleId><json:string>ncb1441</json:string></articleId><language><json:string>eng</json:string></language><originalGenre><json:string>Letter</json:string></originalGenre><qualityIndicators><score>6.012</score><pdfVersion>1.5</pdfVersion><pdfPageSize>595.276 x 782.362 pts</pdfPageSize><refBibsNative>true</refBibsNative><keywordCount>0</keywordCount><abstractCharCount>0</abstractCharCount><pdfWordCount>7626</pdfWordCount><pdfCharCount>50274</pdfCharCount><pdfPageCount>16</pdfPageCount><abstractWordCount>1</abstractWordCount></qualityIndicators><title>A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)KAkt signalling</title><refBibs><json:item><author><json:item><name>T. Kitada</name></json:item></author><host><volume>392</volume><pages><last>608</last><first>605</first></pages><author></author><title>Nature</title></host><title>Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism</title></json:item><json:item><author><json:item><name>C. B. Lucking</name></json:item></author><host><volume>342</volume><pages><last>1567</last><first>1560</first></pages><author></author><title>N. Engl. J. Med.</title></host><title>Association between early-onset Parkinson's disease and mutations in the parkin gene. French Parkinson's Disease Genetics Study Group</title></json:item><json:item><author><json:item><name>H. Shimura</name></json:item></author><host><volume>25</volume><pages><last>305</last><first>302</first></pages><author></author><title>Nature Genet.</title></host><title>Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase</title></json:item><json:item><author><json:item><name>D. J. Moore</name></json:item><json:item><name>A. B. West</name></json:item><json:item><name>V. L. Dawson</name></json:item><json:item><name>T. M. Dawson</name></json:item></author><host><volume>28</volume><pages><last>87</last><first>57</first></pages><author></author><title>Annu. Rev. Neurosci.</title></host><title>Molecular pathophysiology of Parkinson's disease</title></json:item><json:item><author><json:item><name>S. Confalonieri</name></json:item><json:item><name>A. E. Salcini</name></json:item><json:item><name>C. Puri</name></json:item><json:item><name>C. Tacchetti</name></json:item><json:item><name>P. P. Di Fiore</name></json:item></author><host><volume>150</volume><pages><last>912</last><first>905</first></pages><author></author><title>J. Cell Biol.</title></host><title>Tyrosine phosphorylation of Eps15 is required for ligand-regulated, but not constitutive, endocytosis</title></json:item><json:item><author><json:item><name>S. Sigismund</name></json:item></author><host><volume>102</volume><pages><last>2765</last><first>2760</first></pages><author></author><title>Proc. Natl Acad. Sci. USA</title></host><title>Clathrin-independent endocytosis of ubiquitinated cargos</title></json:item><json:item><author><json:item><name>A. A. de Melker</name></json:item><json:item><name>G. van der Horst</name></json:item><json:item><name>J. Borst</name></json:item></author><host><volume>117</volume><pages><last>5012</last><first>5001</first></pages><author></author><title>J. Cell Sci.</title></host><title>c-Cbl directs EGF receptors into an endocytic pathway that involves the ubiquitin-interacting motif of Eps15</title></json:item><json:item><author><json:item><name>D. Hoeller</name></json:item></author><host><volume>8</volume><pages><last>169</last><first>163</first></pages><author></author><title>Nature Cell Biol.</title></host><title>Regulation of ubiquitin-binding proteins by monoubiquitination</title></json:item><json:item><author><json:item><name>A. Brunet</name></json:item><json:item><name>S. R. Datta</name></json:item><json:item><name>M. E. Greenberg</name></json:item></author><host><volume>11</volume><pages><last>305</last><first>297</first></pages><author></author><title>Curr. Opin. Neurobiol.</title></host><title>Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway</title></json:item><json:item><author><json:item><name>A. Hershko</name></json:item><json:item><name>A. Ciechanover</name></json:item></author><host><volume>67</volume><pages><last>479</last><first>425</first></pages><author></author><title>Annu. Rev. Biochem.</title></host><title>The ubiquitin system</title></json:item><json:item><author><json:item><name>M. S. Goldberg</name></json:item></author><host><volume>278</volume><pages><last>43635</last><first>43628</first></pages><author></author><title>J. Biol. Chem.</title></host><title>Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons</title></json:item><json:item><author><json:item><name>H. S. Ko</name></json:item></author><host><volume>25</volume><pages><last>7978</last><first>7968</first></pages><author></author><title>J. Neurosci.</title></host><title>Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death</title></json:item><json:item><author><json:item><name>M. Periquet</name></json:item><json:item><name>O. Corti</name></json:item><json:item><name>S. Jacquier</name></json:item><json:item><name>A. Brice</name></json:item></author><host><volume>95</volume><pages><last>1276</last><first>1259</first></pages><author></author><title>J. Neurochem.</title></host><title>Proteomic analysis of parkin knockout mice: alterations in energy metabolism, protein handling and synaptic function</title></json:item><json:item><author><json:item><name>P. Young</name></json:item><json:item><name>Q. Deveraux</name></json:item><json:item><name>R. E. Beal</name></json:item><json:item><name>C. M. Pickart</name></json:item><json:item><name>M. Rechsteiner</name></json:item></author><host><volume>273</volume><pages><last>5467</last><first>5461</first></pages><author></author><title>J. Biol. Chem.</title></host><title>Characterization of two polyubiquitin binding sites in the 26 S protease subunit 5a</title></json:item><json:item><author><json:item><name>K. J. Walters</name></json:item><json:item><name>M. F. Kleijnen</name></json:item><json:item><name>A. M. Goh</name></json:item><json:item><name>G. Wagner</name></json:item><json:item><name>P. M. Howley</name></json:item></author><host><volume>41</volume><pages><last>1777</last><first>1767</first></pages><author></author><title>Biochemistry</title></host><title>Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a</title></json:item><json:item><author><json:item><name>L. Hicke</name></json:item><json:item><name>R. Dunn</name></json:item></author><host><volume>19</volume><pages><last>172</last><first>141</first></pages><author></author><title>Annu. Rev. Cell. Dev. Biol.</title></host><title>Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins</title></json:item><json:item><author><json:item><name>S. Polo</name></json:item></author><host><volume>416</volume><pages><last>455</last><first>451</first></pages><author></author><title>Nature</title></host><title>A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins</title></json:item><json:item><author><json:item><name>E. Klapisz</name></json:item></author><host><volume>277</volume><pages><last>30753</last><first>30746</first></pages><author></author><title>J. Biol. Chem.</title></host><title>A ubiquitin-interacting motif (UIM) is essential for Eps15 and Eps15R ubiquitination</title></json:item><json:item><author><json:item><name>P. P. Di Fiore</name></json:item><json:item><name>S. Polo</name></json:item><json:item><name>K. Hofmann</name></json:item></author><host><volume>4</volume><pages><last>497</last><first>491</first></pages><author></author><title>Nature Rev. Mol. Cell. Biol.</title></host><title>When ubiquitin meets ubiquitin receptors: a signalling connection</title></json:item><json:item><author><json:item><name>F. Fazioli</name></json:item><json:item><name>L. Minichiello</name></json:item><json:item><name>B. Matoskova</name></json:item><json:item><name>W. T. Wong</name></json:item><json:item><name>P. P. Di Fiore</name></json:item></author><host><volume>13</volume><pages><last>5828</last><first>5814</first></pages><author></author><title>Mol. Cell. Biol.</title></host><title>eps15, a novel tyrosine kinase substrate, exhibits transforming activity</title></json:item><json:item><author><json:item><name>S. van Delft</name></json:item><json:item><name>R. Govers</name></json:item><json:item><name>G. J. Strous</name></json:item><json:item><name>A. J. Verkleij</name></json:item><json:item><name>P. M. van Bergen en Henegouwen</name></json:item></author><host><volume>272</volume><pages><last>14016</last><first>14013</first></pages><author></author><title>J. Biol. Chem.</title></host><title>Epidermal growth factor induces ubiquitination of Eps15</title></json:item><json:item><author><json:item><name>R. Cesari</name></json:item></author><host><volume>100</volume><pages><last>5961</last><first>5956</first></pages><author></author><title>Proc. Natl Acad. Sci. USA</title></host><title>Parkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27</title></json:item><json:item><author><json:item><name>S. R. Denison</name></json:item></author><host><volume>22</volume><pages><last>8378</last><first>8370</first></pages><author></author><title>Oncogene</title></host><title>Alterations in the common fragile site gene Parkin in ovarian and other cancers</title></json:item><json:item><author><json:item><name>A. C. Pawlyk</name></json:item></author><host><volume>278</volume><pages><last>48128</last><first>48120</first></pages><author></author><title>J. Biol. Chem.</title></host><title>Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age</title></json:item><json:item><author><json:item><name>F. Huang</name></json:item><json:item><name>A. Khvorova</name></json:item><json:item><name>W. Marshall</name></json:item><json:item><name>A. Sorkin</name></json:item></author><host><volume>279</volume><pages><last>16661</last><first>16657</first></pages><author></author><title>J. Biol. Chem.</title></host><title>Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference</title></json:item><json:item><author><json:item><name>D. J. Katzmann</name></json:item><json:item><name>G. Odorizzi</name></json:item><json:item><name>S. D. Emr</name></json:item></author><host><volume>3</volume><pages><last>905</last><first>893</first></pages><author></author><title>Nature Rev. Mol. Cell. Biol.</title></host><title>Receptor downregulation and multivesicular-body sorting</title></json:item><json:item><author><json:item><name>M. R. Torrisi</name></json:item></author><host><volume>10</volume><pages><last>434</last><first>417</first></pages><author></author><title>Mol. Biol. Cell</title></host><title>Eps15 is recruited to the plasma membrane upon epidermal growth factor receptor activation and localizes to components of the endocytic pathway during receptor internalization</title></json:item><json:item><author><json:item><name>V. Faundez</name></json:item><json:item><name>R. Krauss</name></json:item><json:item><name>L. Holuigue</name></json:item><json:item><name>J. Garrido</name></json:item><json:item><name>A. Gonzalez</name></json:item></author><host><volume>267</volume><pages><last>20370</last><first>20363</first></pages><author></author><title>J. Biol. Chem.</title></host><title>Epidermal growth factor receptor in synaptic fractions of the rat central nervous system</title></json:item><json:item><author><json:item><name>L. Fallon</name></json:item></author><host><volume>277</volume><pages><last>491</last><first>486</first></pages><author></author><title>J. Biol. Chem.</title></host><title>Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain</title></json:item><json:item><author><json:item><name>V. Koprivica</name></json:item></author><host><volume>310</volume><pages><last>110</last><first>106</first></pages><author></author><title>Science</title></host><title>EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans</title></json:item><json:item><author><json:item><name>Y. Iwakura</name></json:item></author><host><volume>93</volume><pages><last>983</last><first>974</first></pages><author></author><title>J. Neurochem.</title></host><title>Influences of dopaminergic lesion on epidermal growth factor-ErbB signals in Parkinson's disease and its model: neurotrophic implication in nigrostriatal neurons</title></json:item><json:item><author><json:item><name>R. H. Kim</name></json:item></author><host><volume>7</volume><pages><last>273</last><first>263</first></pages><author></author><title>Cancer Cell</title></host><title>DJ-1, a novel regulator of the tumor suppressor PTEN</title></json:item><json:item><author><json:item><name>Y. Yang</name></json:item></author><host><volume>102</volume><pages><last>13675</last><first>13670</first></pages><author></author><title>Proc. Natl Acad. Sci. USA</title></host><title>Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling</title></json:item><json:item><author><json:item><name>K. L. Lim</name></json:item></author><host><volume>25</volume><pages><last>2009</last><first>2002</first></pages><author></author><title>J. Neurosci.</title></host><title>Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation</title></json:item><json:item><author><json:item><name>A. A. Hicks</name></json:item></author><host><volume>52</volume><pages><last>555</last><first>549</first></pages><author></author><title>Ann. Neurol.</title></host><title>A susceptibility gene for late-onset idiopathic Parkinson's disease</title></json:item></refBibs><genre><json:string>research-article</json:string></genre><host><volume>8</volume><pages><total>8</total><last>842</last><first>834</first></pages><issn><json:string>1465-7392</json:string></issn><issue>8</issue><genre><json:string>journal</json:string></genre><language><json:string>unknown</json:string></language><eissn><json:string>1476-4679</json:string></eissn><title>Nature Cell Biology</title></host><categories><wos><json:string>science</json:string><json:string>cell biology</json:string></wos><scienceMetrix><json:string>health sciences</json:string><json:string>biomedical research</json:string><json:string>developmental 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