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Stereochemical aspects of MAO interactions: reversible and selective inhibitors of monoamine oxidase

Identifieur interne : 000D66 ( Istex/Corpus ); précédent : 000D65; suivant : 000D67

Stereochemical aspects of MAO interactions: reversible and selective inhibitors of monoamine oxidase

Auteurs : M. Strolin Benedetti ; P. Dostert

Source :

RBID : ISTEX:94EE8E5214CEF87B591F3008F7BAD5244013C9AE

Abstract

Monoamine oxidase inhibitors have for a long time received ’bad press’. However, the new selective and reversible MAOIs are associated with considerably reduced risk of untoward side-effects. Margherita Strolin Benedetti and Philippe Dostert review the chemistry and pharmacology of these compounds and describe the roles of functional groups and the asymmetric centres of substrates and reversible MAOIs in differential recognition by the A or B forms of MAO.

Url:
DOI: 10.1016/0165-6147(85)90116-6

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ISTEX:94EE8E5214CEF87B591F3008F7BAD5244013C9AE

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   |texte=   Stereochemical aspects of MAO interactions: reversible and selective inhibitors of monoamine oxidase
}}

Wicri

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