Effects of postnatal aluminum exposure on biological parameters in the rat plasma
Identifieur interne : 000776 ( Istex/Corpus ); précédent : 000775; suivant : 000777Effects of postnatal aluminum exposure on biological parameters in the rat plasma
Auteurs : G. Cherroret ; B. Capolaghi ; M.-F. Hutin ; D. Burnel ; D. Desor ; P. R. LehrSource :
- Toxicology Letters [ 0378-4274 ] ; 1995.
Abstract
Young rats were treated by gastric intubation with aluminum chloride (100 mg Al/kg/day) and aluminum lactate (100 and 200 mg Al/kg/day) from postnatal days 5 to 14. This treatment lead to a reduction in body weight. The plasma concentrations of total proteins and albumin decreased whereas the α1 globulins increased in the treated rats. The aluminum concentrations in plasma and hepatic homogenates increased particularly at 200 mg Al lactate. The reduction in average body weight could be attributed to various causes: a decreased food consumption, a transient undernutrition, a reduction of the protein synthesis in the liver. The increase of the plasma concentration of the α1 globulins revealed an inflammation process.
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DOI: 10.1016/0378-4274(95)03239-H
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Hutin</name><affiliation><mods:affiliation>Service de Chimie Générale appliquée á la Médecine, Faculté de Médecine, Université de Nancy 1, Nancy, France</mods:affiliation></affiliation></author><author><name sortKey="Burnel, D" sort="Burnel, D" uniqKey="Burnel D" first="D." last="Burnel">D. Burnel</name><affiliation><mods:affiliation>Laboratoire de Biologie du Comportement, Faculté des Sciences, Université de Nancy 1, Nancy, France</mods:affiliation></affiliation></author><author><name sortKey="Desor, D" sort="Desor, D" uniqKey="Desor D" first="D." last="Desor">D. Desor</name><affiliation><mods:affiliation>Laboratoire de Biologie du Comportement, Faculté des Sciences, Université de Nancy 1, Nancy, France</mods:affiliation></affiliation></author><author><name sortKey="Lehr, P R" sort="Lehr, P R" uniqKey="Lehr P" first="P. R." last="Lehr">P. R. Lehr</name><affiliation><mods:affiliation>Corresponding author.</mods:affiliation></affiliation><affiliation><mods:affiliation>Centre des Sciences de l'Environnement (Neurotoxicologie), Université de Metz, 1 rue des Récollets, B.P. 4025, 57040 Metz Cedex 1. 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France</mods:affiliation></affiliation></author><author><name sortKey="Capolaghi, B" sort="Capolaghi, B" uniqKey="Capolaghi B" first="B." last="Capolaghi">B. Capolaghi</name><affiliation><mods:affiliation>Laboratoire de Biochimie, CHR de Metz-Thionville, Thionville, France</mods:affiliation></affiliation></author><author><name sortKey="Hutin, M F" sort="Hutin, M F" uniqKey="Hutin M" first="M.-F." last="Hutin">M.-F. Hutin</name><affiliation><mods:affiliation>Service de Chimie Générale appliquée á la Médecine, Faculté de Médecine, Université de Nancy 1, Nancy, France</mods:affiliation></affiliation></author><author><name sortKey="Burnel, D" sort="Burnel, D" uniqKey="Burnel D" first="D." last="Burnel">D. Burnel</name><affiliation><mods:affiliation>Laboratoire de Biologie du Comportement, Faculté des Sciences, Université de Nancy 1, Nancy, France</mods:affiliation></affiliation></author><author><name sortKey="Desor, D" sort="Desor, D" uniqKey="Desor D" first="D." last="Desor">D. Desor</name><affiliation><mods:affiliation>Laboratoire de Biologie du Comportement, Faculté des Sciences, Université de Nancy 1, Nancy, France</mods:affiliation></affiliation></author><author><name sortKey="Lehr, P R" sort="Lehr, P R" uniqKey="Lehr P" first="P. R." last="Lehr">P. R. Lehr</name><affiliation><mods:affiliation>Corresponding author.</mods:affiliation></affiliation><affiliation><mods:affiliation>Centre des Sciences de l'Environnement (Neurotoxicologie), Université de Metz, 1 rue des Récollets, B.P. 4025, 57040 Metz Cedex 1. France</mods:affiliation></affiliation></author></analytic><monogr></monogr><series><title level="j">Toxicology Letters</title><title level="j" type="abbrev">TOXLET</title><idno type="ISSN">0378-4274</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1995">1995</date><biblScope unit="volume">78</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="119">119</biblScope><biblScope unit="page" to="125">125</biblScope></imprint><idno type="ISSN">0378-4274</idno></series><idno type="istex">41CA50A6820EC59167E24F8E7B3BC3C5337D8E5A</idno><idno type="DOI">10.1016/0378-4274(95)03239-H</idno><idno type="PII">0378-4274(95)03239-H</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0378-4274</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Young rats were treated by gastric intubation with aluminum chloride (100 mg Al/kg/day) and aluminum lactate (100 and 200 mg Al/kg/day) from postnatal days 5 to 14. This treatment lead to a reduction in body weight. The plasma concentrations of total proteins and albumin decreased whereas the α1 globulins increased in the treated rats. The aluminum concentrations in plasma and hepatic homogenates increased particularly at 200 mg Al lactate. The reduction in average body weight could be attributed to various causes: a decreased food consumption, a transient undernutrition, a reduction of the protein synthesis in the liver. The increase of the plasma concentration of the α1 globulins revealed an inflammation process.</div></front></TEI><istex><corpusName>elsevier</corpusName><author><json:item><name>G. Cherroret</name><affiliations><json:string>Centre des Sciences de l'Environnement (Neurotoxicologie), Université de Metz, 1 rue des Récollets, B.P. 4025, 57040 Metz Cedex 1. France</json:string></affiliations></json:item><json:item><name>B. Capolaghi</name><affiliations><json:string>Laboratoire de Biochimie, CHR de Metz-Thionville, Thionville, France</json:string></affiliations></json:item><json:item><name>M.-F. Hutin</name><affiliations><json:string>Service de Chimie Générale appliquée á la Médecine, Faculté de Médecine, Université de Nancy 1, Nancy, France</json:string></affiliations></json:item><json:item><name>D. Burnel</name><affiliations><json:string>Laboratoire de Biologie du Comportement, Faculté des Sciences, Université de Nancy 1, Nancy, France</json:string></affiliations></json:item><json:item><name>D. Desor</name><affiliations><json:string>Laboratoire de Biologie du Comportement, Faculté des Sciences, Université de Nancy 1, Nancy, France</json:string></affiliations></json:item><json:item><name>P.R. Lehr</name><affiliations><json:string>Corresponding author.</json:string><json:string>Centre des Sciences de l'Environnement (Neurotoxicologie), Université de Metz, 1 rue des Récollets, B.P. 4025, 57040 Metz Cedex 1. France</json:string></affiliations></json:item></author><subject><json:item><lang><json:string>eng</json:string></lang><value>Rat</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Aluminum</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Postnatal intoxication</value></json:item><json:item><lang><json:string>eng</json:string></lang><value>Plasma proteins</value></json:item></subject><language><json:string>eng</json:string></language><originalGenre><json:string>Full-length article</json:string></originalGenre><abstract>Young rats were treated by gastric intubation with aluminum chloride (100 mg Al/kg/day) and aluminum lactate (100 and 200 mg Al/kg/day) from postnatal days 5 to 14. This treatment lead to a reduction in body weight. The plasma concentrations of total proteins and albumin decreased whereas the α1 globulins increased in the treated rats. The aluminum concentrations in plasma and hepatic homogenates increased particularly at 200 mg Al lactate. The reduction in average body weight could be attributed to various causes: a decreased food consumption, a transient undernutrition, a reduction of the protein synthesis in the liver. 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Bohemoslov.</title></host><title>Crcadian rhythm of ketone bodies in the blood of fasting rats</title></json:item></refBibs><genre><json:string>research-article</json:string></genre><serie><volume>Vol. 1</volume><pages><last>363</last><first>353</first></pages><language><json:string>unknown</json:string></language><title>Human Gastrointestinal Development</title></serie><host><volume>78</volume><pii><json:string>S0378-4274(00)X0015-X</json:string></pii><pages><last>125</last><first>119</first></pages><issn><json:string>0378-4274</json:string></issn><issue>2</issue><genre><json:string>journal</json:string></genre><language><json:string>unknown</json:string></language><title>Toxicology Letters</title><publicationDate>1995</publicationDate></host><categories><wos><json:string>science</json:string><json:string>toxicology</json:string></wos><scienceMetrix><json:string>health sciences</json:string><json:string>biomedical research</json:string><json:string>toxicology</json:string></scienceMetrix></categories><publicationDate>1995</publicationDate><copyrightDate>1995</copyrightDate><doi><json:string>10.1016/0378-4274(95)03239-H</json:string></doi><id>41CA50A6820EC59167E24F8E7B3BC3C5337D8E5A</id><score>0.14504488</score><fulltext><json:item><extension>pdf</extension><original>true</original><mimetype>application/pdf</mimetype><uri>https://api.istex.fr/document/41CA50A6820EC59167E24F8E7B3BC3C5337D8E5A/fulltext/pdf</uri></json:item><json:item><extension>zip</extension><original>false</original><mimetype>application/zip</mimetype><uri>https://api.istex.fr/document/41CA50A6820EC59167E24F8E7B3BC3C5337D8E5A/fulltext/zip</uri></json:item><istex:fulltextTEI uri="https://api.istex.fr/document/41CA50A6820EC59167E24F8E7B3BC3C5337D8E5A/fulltext/tei"><teiHeader><fileDesc><titleStmt><title level="a">Effects of postnatal aluminum exposure on biological parameters in the rat plasma</title></titleStmt><publicationStmt><authority>ISTEX</authority><publisher>ELSEVIER</publisher><availability><p>ELSEVIER</p></availability><date>1995</date></publicationStmt><notesStmt><note type="content">Section title: Research article</note></notesStmt><sourceDesc><biblStruct type="inbook"><analytic><title level="a">Effects of postnatal aluminum exposure on biological parameters in the rat plasma</title><author xml:id="author-1"><persName><forename type="first">G.</forename><surname>Cherroret</surname></persName><affiliation>Centre des Sciences de l'Environnement (Neurotoxicologie), Université de Metz, 1 rue des Récollets, B.P. 4025, 57040 Metz Cedex 1. France</affiliation></author><author xml:id="author-2"><persName><forename type="first">B.</forename><surname>Capolaghi</surname></persName><affiliation>Laboratoire de Biochimie, CHR de Metz-Thionville, Thionville, France</affiliation></author><author xml:id="author-3"><persName><forename type="first">M.-F.</forename><surname>Hutin</surname></persName><affiliation>Service de Chimie Générale appliquée á la Médecine, Faculté de Médecine, Université de Nancy 1, Nancy, France</affiliation></author><author xml:id="author-4"><persName><forename type="first">D.</forename><surname>Burnel</surname></persName><affiliation>Laboratoire de Biologie du Comportement, Faculté des Sciences, Université de Nancy 1, Nancy, France</affiliation></author><author xml:id="author-5"><persName><forename type="first">D.</forename><surname>Desor</surname></persName><affiliation>Laboratoire de Biologie du Comportement, Faculté des Sciences, Université de Nancy 1, Nancy, France</affiliation></author><author xml:id="author-6"><persName><forename type="first">P.R.</forename><surname>Lehr</surname></persName><affiliation>Corresponding author.</affiliation><affiliation>Centre des Sciences de l'Environnement (Neurotoxicologie), Université de Metz, 1 rue des Récollets, B.P. 4025, 57040 Metz Cedex 1. France</affiliation></author></analytic><monogr><title level="j">Toxicology Letters</title><title level="j" type="abbrev">TOXLET</title><idno type="pISSN">0378-4274</idno><idno type="PII">S0378-4274(00)X0015-X</idno><imprint><publisher>ELSEVIER</publisher><date type="published" when="1995"></date><biblScope unit="volume">78</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="119">119</biblScope><biblScope unit="page" to="125">125</biblScope></imprint></monogr><idno type="istex">41CA50A6820EC59167E24F8E7B3BC3C5337D8E5A</idno><idno type="DOI">10.1016/0378-4274(95)03239-H</idno><idno type="PII">0378-4274(95)03239-H</idno></biblStruct></sourceDesc></fileDesc><profileDesc><creation><date>1995</date></creation><langUsage><language ident="en">en</language></langUsage><abstract xml:lang="en"><p>Young rats were treated by gastric intubation with aluminum chloride (100 mg Al/kg/day) and aluminum lactate (100 and 200 mg Al/kg/day) from postnatal days 5 to 14. This treatment lead to a reduction in body weight. The plasma concentrations of total proteins and albumin decreased whereas the α1 globulins increased in the treated rats. The aluminum concentrations in plasma and hepatic homogenates increased particularly at 200 mg Al lactate. The reduction in average body weight could be attributed to various causes: a decreased food consumption, a transient undernutrition, a reduction of the protein synthesis in the liver. The increase of the plasma concentration of the α1 globulins revealed an inflammation process.</p></abstract><textClass><keywords scheme="keyword"><list><head>Keywords</head><item><term>Rat</term></item><item><term>Aluminum</term></item><item><term>Postnatal intoxication</term></item><item><term>Plasma proteins</term></item></list></keywords></textClass></profileDesc><revisionDesc><change when="1994-11-21">Modified</change><change when="1995">Published</change></revisionDesc></teiHeader></istex:fulltextTEI><json:item><extension>txt</extension><original>false</original><mimetype>text/plain</mimetype><uri>https://api.istex.fr/document/41CA50A6820EC59167E24F8E7B3BC3C5337D8E5A/fulltext/txt</uri></json:item></fulltext><metadata><istex:metadataXml wicri:clean="Elsevier, elements deleted: tail"><istex:xmlDeclaration>version="1.0" encoding="utf-8"</istex:xmlDeclaration><istex:docType PUBLIC="-//ES//DTD journal article DTD version 4.5.2//EN//XML" URI="art452.dtd" name="istex:docType"></istex:docType><istex:document><converted-article version="4.5.2" docsubtype="fla"><item-info><jid>TOXLET</jid><aid>9503239H</aid><ce:pii>0378-4274(95)03239-H</ce:pii><ce:doi>10.1016/0378-4274(95)03239-H</ce:doi><ce:copyright type="unknown" year="1995"></ce:copyright></item-info><head><ce:dochead><ce:textfn>Research article</ce:textfn></ce:dochead><ce:title>Effects of postnatal aluminum exposure on biological parameters in the rat plasma</ce:title><ce:author-group><ce:author><ce:given-name>G.</ce:given-name><ce:surname>Cherroret</ce:surname><ce:cross-ref refid="AFF1"><ce:sup>a</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>B.</ce:given-name><ce:surname>Capolaghi</ce:surname><ce:cross-ref refid="AFF2"><ce:sup>b</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>M.-F.</ce:given-name><ce:surname>Hutin</ce:surname><ce:cross-ref refid="AFF3"><ce:sup>c</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>D.</ce:given-name><ce:surname>Burnel</ce:surname><ce:cross-ref refid="AFF4"><ce:sup>d</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>D.</ce:given-name><ce:surname>Desor</ce:surname><ce:cross-ref refid="AFF4"><ce:sup>d</ce:sup></ce:cross-ref></ce:author><ce:author><ce:given-name>P.R.</ce:given-name><ce:surname>Lehr</ce:surname><ce:cross-ref refid="COR1"><ce:sup>∗</ce:sup></ce:cross-ref><ce:cross-ref refid="AFF1"><ce:sup>a</ce:sup></ce:cross-ref></ce:author><ce:affiliation id="AFF1"><ce:label>a</ce:label><ce:textfn>Centre des Sciences de l'Environnement (Neurotoxicologie), Université de Metz, 1 rue des Récollets, B.P. 4025, 57040 Metz Cedex 1. France</ce:textfn></ce:affiliation><ce:affiliation id="AFF2"><ce:label>b</ce:label><ce:textfn>Laboratoire de Biochimie, CHR de Metz-Thionville, Thionville, France</ce:textfn></ce:affiliation><ce:affiliation id="AFF3"><ce:label>c</ce:label><ce:textfn>Service de Chimie Générale appliquée á la Médecine, Faculté de Médecine, Université de Nancy 1, Nancy, France</ce:textfn></ce:affiliation><ce:affiliation id="AFF4"><ce:label>d</ce:label><ce:textfn>Laboratoire de Biologie du Comportement, Faculté des Sciences, Université de Nancy 1, Nancy, France</ce:textfn></ce:affiliation><ce:correspondence id="COR1"><ce:label>∗</ce:label><ce:text>Corresponding author.</ce:text></ce:correspondence></ce:author-group><ce:date-received day="2" month="11" year="1993"></ce:date-received><ce:date-revised day="21" month="11" year="1994"></ce:date-revised><ce:date-accepted day="22" month="11" year="1994"></ce:date-accepted><ce:abstract><ce:section-title>Abstract</ce:section-title><ce:abstract-sec><ce:simple-para>Young rats were treated by gastric intubation with aluminum chloride (100 mg Al/kg/day) and aluminum lactate (100 and 200 mg Al/kg/day) from postnatal days 5 to 14. This treatment lead to a reduction in body weight. The plasma concentrations of total proteins and albumin decreased whereas the α1 globulins increased in the treated rats. The aluminum concentrations in plasma and hepatic homogenates increased particularly at 200 mg Al lactate. The reduction in average body weight could be attributed to various causes: a decreased food consumption, a transient undernutrition, a reduction of the protein synthesis in the liver. The increase of the plasma concentration of the α1 globulins revealed an inflammation process.</ce:simple-para></ce:abstract-sec></ce:abstract><ce:keywords><ce:section-title>Keywords</ce:section-title><ce:keyword><ce:text>Rat</ce:text></ce:keyword><ce:keyword><ce:text>Aluminum</ce:text></ce:keyword><ce:keyword><ce:text>Postnatal intoxication</ce:text></ce:keyword><ce:keyword><ce:text>Plasma proteins</ce:text></ce:keyword></ce:keywords></head></converted-article></istex:document></istex:metadataXml><mods version="3.6"><titleInfo><title>Effects of postnatal aluminum exposure on biological parameters in the rat plasma</title></titleInfo><titleInfo type="alternative" contentType="CDATA"><title>Effects of postnatal aluminum exposure on biological parameters in the rat plasma</title></titleInfo><name type="personal"><namePart type="given">G.</namePart><namePart type="family">Cherroret</namePart><affiliation>Centre des Sciences de l'Environnement (Neurotoxicologie), Université de Metz, 1 rue des Récollets, B.P. 4025, 57040 Metz Cedex 1. France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">B.</namePart><namePart type="family">Capolaghi</namePart><affiliation>Laboratoire de Biochimie, CHR de Metz-Thionville, Thionville, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">M.-F.</namePart><namePart type="family">Hutin</namePart><affiliation>Service de Chimie Générale appliquée á la Médecine, Faculté de Médecine, Université de Nancy 1, Nancy, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D.</namePart><namePart type="family">Burnel</namePart><affiliation>Laboratoire de Biologie du Comportement, Faculté des Sciences, Université de Nancy 1, Nancy, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">D.</namePart><namePart type="family">Desor</namePart><affiliation>Laboratoire de Biologie du Comportement, Faculté des Sciences, Université de Nancy 1, Nancy, France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">P.R.</namePart><namePart type="family">Lehr</namePart><affiliation>Corresponding author.</affiliation><affiliation>Centre des Sciences de l'Environnement (Neurotoxicologie), Université de Metz, 1 rue des Récollets, B.P. 4025, 57040 Metz Cedex 1. France</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="research-article" displayLabel="Full-length article"></genre><originInfo><publisher>ELSEVIER</publisher><dateIssued encoding="w3cdtf">1995</dateIssued><dateModified encoding="w3cdtf">1994-11-21</dateModified><copyrightDate encoding="w3cdtf">1995</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm><languageTerm type="code" authority="rfc3066">en</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="en">Young rats were treated by gastric intubation with aluminum chloride (100 mg Al/kg/day) and aluminum lactate (100 and 200 mg Al/kg/day) from postnatal days 5 to 14. This treatment lead to a reduction in body weight. The plasma concentrations of total proteins and albumin decreased whereas the α1 globulins increased in the treated rats. The aluminum concentrations in plasma and hepatic homogenates increased particularly at 200 mg Al lactate. The reduction in average body weight could be attributed to various causes: a decreased food consumption, a transient undernutrition, a reduction of the protein synthesis in the liver. The increase of the plasma concentration of the α1 globulins revealed an inflammation process.</abstract><note type="content">Section title: Research article</note><subject><genre>Keywords</genre><topic>Rat</topic><topic>Aluminum</topic><topic>Postnatal intoxication</topic><topic>Plasma proteins</topic></subject><relatedItem type="host"><titleInfo><title>Toxicology Letters</title></titleInfo><titleInfo type="abbreviated"><title>TOXLET</title></titleInfo><genre type="journal">journal</genre><originInfo><dateIssued encoding="w3cdtf">199507</dateIssued></originInfo><identifier type="ISSN">0378-4274</identifier><identifier type="PII">S0378-4274(00)X0015-X</identifier><part><date>199507</date><detail type="volume"><number>78</number><caption>vol.</caption></detail><detail type="issue"><number>2</number><caption>no.</caption></detail><extent unit="issue pages"><start>87</start><end>174</end></extent><extent unit="pages"><start>119</start><end>125</end></extent></part></relatedItem><identifier type="istex">41CA50A6820EC59167E24F8E7B3BC3C5337D8E5A</identifier><identifier type="DOI">10.1016/0378-4274(95)03239-H</identifier><identifier type="PII">0378-4274(95)03239-H</identifier><recordInfo><recordContentSource>ELSEVIER</recordContentSource></recordInfo></mods></metadata></istex></record>Pour manipuler ce document sous Unix (Dilib)
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